Australian New Crops Info 2016
Supported by the Rural Industries Research and Development Corporation

Listing of Interesting Plants of the World:

Taxus brevifolia

 

 

This species is usually known as:

Taxus brevifolia

 

This species has also been known as:

Taxus brevifolia var. polychaeta, Taxus brevifolia subsp. polychaeta, Taxus brevifolia var. reptaneta, Taxus brevifolia subsp. reptaneta

 

Common names:

Pacific Yew

 

 

Trends (five databases) 1901-2013:
[Number of papers mentioning Taxus brevifolia: 1559]

 

 

Popularity of Taxus brevifolia over time
[Left-hand Plot: Plot of numbers of papers mentioning Taxus brevifolia (histogram and left hand axis scale of left-hand plot) and line of best fit, 1901 to 2013 (equation and % variation accounted for in box); Right-hand Plot: Plot of a proportional micro index, derived from numbers of papers mentioning Taxus brevifolia as a proportion (scaled by multiplying by one million) of the approximate total number of papers available in databases for that year (frequency polygon and left-hand axis scale of right-hand plot) and line of best fit, 1901 to 2013 (equation and % variation accounted for in box)] 

[For larger charts showing the numbers of papers that have mentioned this species over years, select this link; there are links to come back from there]

 

Keywords

[Total number of keywords included in the papers that mentioned this species: 7228]

 

7 (2), Paclitaxel (302), taxol (144), Taxus brevifolia (98), Taxus (84), apoptosis (47), diterpenoids (45), Taxanes (39), Natural products (34), biosynthesis (33), chemotherapy (33), Cytotoxicity (33), Cancer (32), Taxus cuspidata (32), medicinal plants (31), Taxaceae (31), bark (29), docetaxel (28), drug delivery (26), secondary metabolites (26), Taxus baccata (25), Tubulin (24), chemical constituents of <ARROW plants (23), antineoplastic agents (21), Nanoparticles (20), pharmacokinetics (20), Taxoids (20), Endophytic fungus (18), microtubules (18), plant cell culture (18), alkaloids (17), yew (16), cell culture (15), chemical structure (15), Purification (15), Endophytic fungi (14), metabolic engineering (14), ovarian cancer (14), anticancer (13), conifer needles (13), drug discovery (13), Nitric oxide (13), P-Glycoprotein (12), synthesis (12), Anticancer agents (11), cell cycle (11), drugs (11), restenosis (11), endophytes (10), plant extracts (10), spectral analysis (10), tissue culture (10), anticancer drugs (9), Bioavailability (9), biodiversity (9), Breast cancer (9), British Columbia (9), Drug resistance (9), fungi (9), Nanoparticle (9), quantitative analysis (9), terpenes (9), total synthesis (9), anticancer drug (8), artemisinin (8), Bcl-2 (8), Biodegradable polymers (8), Cisplatin (8), culture media (8), Elicitation (8), growth (8), methyl jasmonate (8), Micelle (8), Signal transduction (8), Taxol® (8), Taxus canadensis (8), TaxusDOWN> chinensis var. mairei (8), Taxus media (8), Terpenoids (8), Antibiotics (7), Anti-cancer (7), Antitumor agents (7), baccatin III (7), Camptothecin (7), Cell cultures (7), drug-eluting stents (7), Endophyte (7), Fermentation (7), Gene expression (7), high performance liquid chromatography (7), Liposomes (7), mass spectrometry (7), molecular conformation (7), p53 (7), Prodrug (7), terpenoid (7), 10-Deacetylbaccatin III (6), angiogenesis (6), anticancer activity (6), Baccatin (6), Biocatalysis (6)…..

 

[If all keywords are not here (as indicated by .....), they can be accessed from this link; there are links to come back from there]

 

 

Most likely scope for crop use/product (%):
[Please note: When there are only a few papers mentioning a species, care should be taken with the interpretation of these crop use/product results; as well, a mention may relate to the use of a species, or the context in which it grows, rather than a product]

 

poison (54.07), medicinal (16.81), resin (3.84), fruit (3.46), weed (2.99), timber (2.15), genetics (1.37), grain legume (1.29), ornamental (1.11), industrial product (1.00)…..

 

[To see the full list of crop use/product outcomes, from searching abstracts of the papers that have mentioned this species, select this link; details of the analysis process have also been included; there are links to come back from there]

 

 

Recent mentions of this species in the literature:
[since 2012, with links to abstracts; The references from 1901-2013 which have been used for the trend, keyword and crop use/product analyses below, are listed below these references]

 

(2017) Subject Index. In Biotechnology for Beginners (Second Edition). (Ed.^(Eds  pp. 407-425. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128012246000254

(2017) Index A2 - Badal, Simone. In Pharmacognosy. (Ed.^(Eds Delgoda R) pp. 687-716. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128021040000512

Andrews GR and Roberts SC (2017) Bioprocess Engineering of Plant Cell Suspension Cultures. In Applied Bioengineering. (Ed.^(Eds  pp. 283-326. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527800599.ch10

Chen Y and Chen Z (2017) COF-1-modified magnetic nanoparticles for highly selective and efficient solid-phase microextraction of paclitaxel. Talanta 165, 188-193. //www.sciencedirect.com/science/article/pii/S0039914016309845

Davey M (2017) Secondary Metabolism in Plant Cell Cultures A2 - Thomas, Brian. In Encyclopedia of Applied Plant Sciences (Second Edition). (Ed.^(Eds Murray BG and Murphy DJ) pp. 462-467. (Academic Press: Oxford). //www.sciencedirect.com/science/article/pii/B9780123948076001465

Derese S, Guantai EM, Souaibou Y and Kuete V (2017) Chapter 21 - Mangifera indica L. (Anacardiaceae). In Medicinal Spices and Vegetables from Africa. (Ed.^(Eds  pp. 451-483. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780128092866000212

Dziggel C, Schäfer H and Wink M (2017) Tools of pathway reconstruction and production of economically relevant plant secondary metabolites in recombinant microorganisms. Biotechnology Journal 12, n/a-n/a. http://dx.doi.org/10.1002/biot.201600145

Garg S and Serruys PW (2017) Drug Eluting Stents. In Reference Module in Materials Science and Materials Engineering. (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780128035818101468

Gautam M, Patwardhan B, Gairola S and Jadhav S (2017) Chapter 11 - Vaccines and Immunodrugs Discovery. In Innovative Approaches in Drug Discovery. (Ed.^(Eds  pp. 315-341. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128018149000118

Geetha Bai R, Muthoosamy K, Shipton FN and Manickam S (2017) Acoustic cavitation induced generation of stabilizer-free, extremely stable reduced graphene oxide nanodispersion for efficient delivery of paclitaxel in cancer cells. Ultrasonics Sonochemistry 36, 129-138. //www.sciencedirect.com/science/article/pii/S135041771630390X

Gerwick WH (2017) Plant Sources of Drugs and Chemicals. In Reference Module in Life Sciences. (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780128096338023062

Hoyos P, Hernáiz MJ and Alcántara AR (2017) Biocatalyzed Production of Fine Chemicals. In Reference Module in Life Sciences. (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780128096338091536

Ishii HR, Sillett SC and Carroll AL (2017) Crown dynamics and wood production of Douglas-fir trees in an old-growth forest. Forest Ecology and Management 384, 157-168. //www.sciencedirect.com/science/article/pii/S0378112716308398

Kukula-Koch WA and Widelski J (2017) Chapter 9 - Alkaloids A2 - Badal, Simone. In Pharmacognosy. (Ed.^(Eds Delgoda R) pp. 163-198. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128021040000093

Lin K-H, Shibu MA, Kuo Y-H, Chen Y-C, Hsu H-H, Bau D-T, Chen M-C, Tu C-C, Viswanadha VP and Huang C-Y (2017) Taiwanin C selectively inhibits arecoline and 4-NQO-induced oral cancer cell proliferation via ERK1/2 inactivation. Environmental Toxicology 32, 62-69. http://dx.doi.org/10.1002/tox.22212

Ludwiczuk A, Skalicka-Woźniak K and Georgiev MI (2017) Chapter 11 - Terpenoids A2 - Badal, Simone. In Pharmacognosy. (Ed.^(Eds Delgoda R) pp. 233-266. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128021040000111

Mafu S, Karunanithi PS, Palazzo TA, Harrod BL, Rodriguez SM, Mollhoff IN, OBrien TE, Tong S, Fiehn O, Tantillo DJ, Bohlmann J, #x, rg and Zerbe P (2017) Biosynthesis of the microtubule-destabilizing diterpene pseudolaric acid B from golden larch involves an unusual diterpene synthase. PNAS, 1612901114. http://www.pnas.org/cgi/content/abstract/1612901114v1

Marchev A and Georgiev M (2017) 4 - Plant Cell Bioprocesses A2 - Larroche, Christian. In Current Developments in Biotechnology and Bioengineering. (Ed.^(Eds Sanromán MÁ, Du G and Pandey A) pp. 73-95. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444636638000045

Mathibe LJ, Botha J and Naidoo S (2017) Effects of Z-venusol, isolated from Gunnera perpensa L., on IL-6 and cAMP activity in human breast cancer cells in vitro. South African Journal of Botany 108, 96-99. //www.sciencedirect.com/science/article/pii/S0254629916303891

Mendes T, Castiglione F, Tieri P and Felicori L (2017) 9 - Systems and Synthetic Biology Applied to Health. In Current Developments in Biotechnology and Bioengineering. (Ed.^(Eds  pp. 183-213. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444636607000097

Murray BG (2017) Plant Diversity, Conservation and Use. In Encyclopedia of Applied Plant Sciences (Second Edition). (Ed.^(Eds  pp. 289-308. (Academic Press: Oxford). //www.sciencedirect.com/science/article/pii/B9780123948076000472

Naman CB, Benatrehina PA and Kinghorn AD (2017) Pharmaceuticals, Plant Drugs A2 - Thomas, Brian. In Encyclopedia of Applied Plant Sciences (Second Edition). (Ed.^(Eds Murray BG and Murphy DJ) pp. 93-99. (Academic Press: Oxford). //www.sciencedirect.com/science/article/pii/B9780123948076001635

Peyrat L-A, Eparvier V, Eydoux C, Guillemot J-C, Litaudon M and Stien D (2017) Betulinic Acid, The First Lupane-Type Triterpenoid Isolated from Both a Phomopsis sp. and Its Host Plant Diospyros carbonaria Benoist. Chemistry & Biodiversity 14, n/a-n/a. http://dx.doi.org/10.1002/cbdv.201600171

Renneberg R, Berkling V and Loroch V (2017) Chapter 9 - Myocardial Infarction, Cancer, and Stem Cells: Biotechnology is a Life Saver. In Biotechnology for Beginners (Second Edition). (Ed.^(Eds  pp. 311-342. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128012246000096

Renneberg R, Berkling V and Loroch V (2017) Chapter 7 - Green Biotechnology. In Biotechnology for Beginners (Second Edition). (Ed.^(Eds  pp. 233-279. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128012246000072

Shields M (2017) Chapter 14 - Chemotherapeutics A2 - Badal, Simone. In Pharmacognosy. (Ed.^(Eds Delgoda R) pp. 295-313. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128021040000147

Singh R, Kumari P and Kumar S (2017) 11 - Nanotechnology for enhanced bioactivity of bioactive phytomolecules A2 - Grumezescu, Alexandru Mihai. In Nutrient Delivery. (Ed.^(Eds  pp. 413-456. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780128043042000111

Sohn JS, Yoon D-S, Sohn JY, Park J-S and Choi J-S (2017) Development and evaluation of targeting ligands surface modified paclitaxel nanocrystals. Materials Science and Engineering: C 72, 228-237. //www.sciencedirect.com/science/article/pii/S0928493116322378

Somaiah NM and Prakash HS (2017) Diversity and bioprospecting of actinomycete endophytes from the medicinal plants. Letters in Applied Microbiology, n/a-n/a. http://dx.doi.org/10.1111/lam.12718

Tao J, Yan R, Zhao L, Wang D and Xu X (2017) Separation and purification of two taxanes and one xylosyl-containing taxane from Taxus wallichiana Zucc.: A comparison between high-speed counter-current chromatography and reversed-phase flash chromatography. Journal of Separation Science, n/a-n/a. http://dx.doi.org/10.1002/jssc.201601066

Turfus SC, Delgoda R, Picking D and Gurley BJ (2017) Chapter 25 - Pharmacokinetics. In Pharmacognosy. (Ed.^(Eds  pp. 495-512. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128021040000251

Vettraino A, Brasier CM, Webber JF, Hansen EM, Green S, Robin C, Tomassini A, Bruni N and Vannini A (2017) Contrasting microsatellite diversity in the evolutionary lineages of Phytophthora lateralis. Fungal Biology 121, 112-126. //www.sciencedirect.com/science/article/pii/S1878614616301556

Woods N, Niwasabutra K, Acevedo R, Igoli J, Altwaijry NA, Tusiimire J, Gray AI, Watson DG and Ferro VA (2017) Chapter 11 - Natural Vaccine Adjuvants and Immunopotentiators Derived From Plants, Fungi, Marine Organisms, and Insects A2 - Schijns, Virgil E.J.C. In Immunopotentiators in Modern Vaccines (Second Edition). (Ed.^(Eds OHagan DT) pp. 211-229. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780128040195000116

Yordanova ZP and Georgiev MI (2017) Cell Factories A2 - Thomas, Brian. In Encyclopedia of Applied Plant Sciences (Second Edition). (Ed.^(Eds Murray BG and Murphy DJ) pp. 72-76. (Academic Press: Oxford). //www.sciencedirect.com/science/article/pii/B9780123948076001581

Zhang T, Luo J, Fu Y, Li H, Ding R, Gong T and Zhang Z (2017) Novel oral administrated paclitaxel micelles with enhanced bioavailability and antitumor efficacy for resistant breast cancer. Colloids and Surfaces B: Biointerfaces 150, 89-97. //www.sciencedirect.com/science/article/pii/S0927776516308050

(2016) Taxaceae A2 - Aronson, J.K. In Meylers Side Effects of Drugs (Sixteenth Edition). (Ed.^(Eds  pp. 706-707. (Elsevier: Oxford). //www.sciencedirect.com/science/article/pii/B9780444537171015055

(2016) Subject Index. In Methods in Enzymology. (Ed.^(Eds Sarah EOC) pp. 419-428. (Academic Press). //www.sciencedirect.com/science/article/pii/S0076687916301884

(2016) 14 - Phytopharmaka bei Tumorerkrankungen A2 - Schilcher, Heinz. In Leitfaden Phytotherapie (5. Auflage). (Ed.^(Eds  pp. 1017-1034. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B9783437553448000144

(2016) Paclitaxel A2 - Aronson, J.K. In Meylers Side Effects of Drugs (Sixteenth Edition). (Ed.^(Eds  pp. 445-452. (Elsevier: Oxford). //www.sciencedirect.com/science/article/pii/B9780444537171012130

(2016) Subject Index. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 399-419. (Elsevier). //www.sciencedirect.com/science/article/pii/B978044463601020001X

(2016) Speed Talks. The FEBS Journal 283, 57-126. http://dx.doi.org/10.1111/febs.13807

Akyol Z, Çoker-Gürkan A, Arisan ED, Obakan-Yerlikaya P and Palavan-Ünsal N (2016) DENSpm overcame Bcl-2 mediated resistance against Paclitaxel treatment in MCF-7 breast cancer cells via activating polyamine catabolic machinery. Biomedicine & Pharmacotherapy 84, 2029-2041. //www.sciencedirect.com/science/article/pii/S0753332216312446

Ali-Seyed M, Jantan I, Vijayaraghavan K and Bukhari SNA (2016) Betulinic Acid: Recent Advances in Chemical Modifications, Effective Delivery, and Molecular Mechanisms of a Promising Anticancer Therapy. Chemical Biology & Drug Design 87, 517-536. http://dx.doi.org/10.1111/cbdd.12682

Amtul Z and Atta ur R (2016) Chapter 11 - Nutraceuticals Neuroprotect Naturally: Alzheimer’s disease, Parkinson’s disease, Stroke and Major Depressive Disorder. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 373-397. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444637499000116

Anastas PT and Hammond DG (2016) Chapter 4 - Case Studies—Green Chemistry in Practice. In Inherent Safety At Chemical Sites. (Ed.^(Eds  pp. 23-118. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780128041901000045

Anwar M, Akhter S, Mallick N, Mohapatra S, Zafar S, Rizvi MMA, Ali A and Ahmad FJ (2016) Enhanced anti-tumor efficacy of paclitaxel with PEGylated lipidic nanocapsules in presence of curcumin and poloxamer: In vitro and in vivo studies. Pharmacological Research 113, Part A, 146-165. //www.sciencedirect.com/science/article/pii/S1043661816308155

Arendt P, Pollier J, Callewaert N and Goossens A (2016) Synthetic biology for production of natural and new-to-nature terpenoids in photosynthetic organisms. The Plant Journal 87, 16-37. http://dx.doi.org/10.1111/tpj.13138

Atta ur R (2016) Preface. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. xiii-xiv. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444636010220012

Bahmani M, Shirzad H, Shahinfard N, Sheivandi L and Rafieian-Kopaei M (2016) Cancer Phytotherapy: Recent Views on the Role of Antioxidant and Angiogenesis Activities. Journal of Evidence-Based Complementary & Alternative Medicine, 2156587215625157. http://chp.sagepub.com/cgi/content/abstract/2156587215625157v2

Bakrania AK, Variya BC and Patel SS (2016) Novel targets for paclitaxel nano formulations: Hopes and hypes in triple negative breast cancer. Pharmacological Research 111, 577-591. //www.sciencedirect.com/science/article/pii/S1043661816306995

Becker J and Wittmann C (2016) Systems metabolic engineering of Escherichia coli for the heterologous production of high value molecules — a veteran at new shores. Current Opinion in Biotechnology 42, 178-188. //www.sciencedirect.com/science/article/pii/S0958166916301392

Biersack B (2016) Current state of phenolic and terpenoidal dietary factors and natural products as non-coding RNA/microRNA modulators for improved cancer therapy and prevention. Non-coding RNA Research 1, 12-34. //www.sciencedirect.com/science/article/pii/S2468054016300026

Biggs BW, Lim CG, Sagliani K, Shankar S, Stephanopoulos G, De Mey M and Ajikumar PK (2016) Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in Escherichia coli. PNAS 113, 3209-3214. http://www.pnas.org/cgi/content/abstract/113/12/3209

Bilia AR, Bergonzi MC, Guccione C, Manconi M, Fadda AM and Sinico C (2016) Vesicles and micelles: Two versatile vectors for the delivery of natural products. Journal of Drug Delivery Science and Technology 32, Part B, 241-255. //www.sciencedirect.com/science/article/pii/S1773224715300174

Bishayee A and Sethi G (2016) Bioactive natural products in cancer prevention and therapy: Progress and promise. Seminars in Cancer Biology 40–41, 1-3. //www.sciencedirect.com/science/article/pii/S1044579X16300396

Bouabdallah S, Sghaier R-M, Selmi S, Khlifi D, Laouini D and Ben-Attia M (2016) Current approaches and challenges for chemical characterization of inhibitory effect against cancer cell line isolated from Gokshur extract. Journal of Chromatography B 1026, 279-285. //www.sciencedirect.com/science/article/pii/S1570023215302877

Bretschneider A, Heckel DG and Vogel H (2016) Know your ABCs: Characterization and gene expression dynamics of ABC transporters in the polyphagous herbivore Helicoverpa armigera. Insect Biochemistry and Molecular Biology 72, 1-9. //www.sciencedirect.com/science/article/pii/S0965174816300212

Brody T (2016) Chapter 1 - Origins of Drugs. In Clinical Trials (Second Edition). (Ed.^(Eds  pp. 1-30. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128042175000011

Cadamuro M, Spagnuolo G, Sambado L, Indraccolo S, Nardo G, Rosato A, Brivio S, Caslini C, Stecca T, Massani M, Bassi N, Novelli E, Spirli C, Fabris L and Strazzabosco M (2016) Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma. Cancer Res. 76, 4775-4784. http://cancerres.aacrjournals.org/cgi/content/abstract/76/16/4775

Case MJ and Lawler JJ (2016) Integrating mechanistic and empirical model projections to assess climate impacts on tree species distributions in northwestern North America. Global Change Biology, n/a-n/a. http://dx.doi.org/10.1111/gcb.13570

Chen J, Duan B, Xu G, Korpelainen H, Niinemets U, #x, lo and Li C (2016) Sexual competition affects biomass partitioning, carbon-nutrient balance, Cd allocation and ultrastructure of Populus cathayana females and males exposed to Cd stress. Tree Physiol 36, 1353-1368. http://treephys.oxfordjournals.org/cgi/content/abstract/36/11/1353

Chen J, Liu M, Liu X, Miao J, Fu C, Gao H, Müller R, Zhang Q and Zhang L (2016) Interrogation of Streptomyces avermitilis for efficient production of avermectins. Synthetic and Systems Biotechnology 1, 7-16. //www.sciencedirect.com/science/article/pii/S2405805X16000028

Chen M, Harris GG, Pemberton TA and Christianson DW (2016) Multi-domain terpenoid cyclase architecture and prospects for proximity in bifunctional catalysis. Current Opinion in Structural Biology 41, 27-37. //www.sciencedirect.com/science/article/pii/S0959440X16300458

CHEN X, LIU Y, WU J, HUANG H, DU Z, ZHANG K, ZHOU D, HUNG K, GOODIN S and ZHENG X (2016) Mechanistic Study of Inhibitory Effects of Atorvastatin and Docetaxel in Combination on Prostate Cancer. Cancer Genomics Proteomics 13, 151-160. http://cgp.iiarjournals.org/cgi/content/abstract/13/2/151

Cheng Y-T, Yang C-C and Shyur L-F (2016) Phytomedicine—Modulating oxidative stress and the tumor microenvironment for cancer therapy. Pharmacological Research 114, 128-143. //www.sciencedirect.com/science/article/pii/S1043661816306570

Choi J-S and Park J-S (2016) Effects of paclitaxel nanocrystals surface charge on cell internalization. European Journal of Pharmaceutical Sciences 93, 90-96. //www.sciencedirect.com/science/article/pii/S0928098716303037

Chu B, Qu Y, Huang Y, Zhang L, Chen X, Long C, He Y, Ou C and Qian Z (2016) PEG-derivatized octacosanol as micellar carrier for paclitaxel delivery. International Journal of Pharmaceutics 500, 345-359. //www.sciencedirect.com/science/article/pii/S037851731630028X

Cook JG, Cook RC, Davis RW and Irwin LL (2016) Nutritional ecology of elk during summer and autumn in the Pacific Northwest. Wildlife Monographs 195, 1-81. http://dx.doi.org/10.1002/wmon.1020

Danyuo Y, Dozie-Nwachukwu S, Obayemi JD, Ani CJ, Odusanya OS, Oni Y, Anuku N, Malatesta K and Soboyejo WO (2016) Swelling of poly(N-isopropylacrylamide) P(NIPA)-based hydrogels with bacterial-synthesized prodigiosin for localized cancer drug delivery. Materials Science and Engineering: C 59, 19-29. //www.sciencedirect.com/science/article/pii/S0928493115304161

Deepika VB, Murali TS and Satyamoorthy K (2016) Modulation of genetic clusters for synthesis of bioactive molecules in fungal endophytes: A review. Microbiological Research 182, 125-140. //www.sciencedirect.com/science/article/pii/S0944501315300227

Di Marzio L, Ventura CA, Cosco D, Paolino D, Di Stefano A, Stancanelli R, Tommasini S, Cannavŕ C, Celia C and Fresta M (2016) Nanotherapeutics for anti-inflammatory delivery. Journal of Drug Delivery Science and Technology 32, Part B, 174-191. //www.sciencedirect.com/science/article/pii/S1773224715300447

Diederich M and Cerella C (2016) Non-canonical programmed cell death mechanisms triggered by natural compounds. Seminars in Cancer Biology 40–41, 4-34. //www.sciencedirect.com/science/article/pii/S1044579X16300219

Dold S-M, Cai L and Rudat J (2016) One-step purification and immobilization of a β-amino acid aminotransferase using magnetic (M-PVA) beads. Engineering in Life Sciences 16, 568-576. http://dx.doi.org/10.1002/elsc.201600042

Domalaon R, Findlay B, Ogunsina M, Arthur G and Schweizer F (2016) Ultrashort cationic lipopeptides and lipopeptoids: Evaluation and mechanistic insights against epithelial cancer cells. Peptides 84, 58-67. //www.sciencedirect.com/science/article/pii/S0196978116301450

Dong Y-s, Fu C-h, Su P, Xu X-p, Yuan J, Wang S, Zhang M, Zhao C-f and Yu L-j (2016) Mechanisms and effective control of physiological browning phenomena in plant cell cultures. Physiologia Plantarum 156, 13-28. http://dx.doi.org/10.1111/ppl.12382

Donzelli BGG and Krasnoff SB (2016) Chapter Ten - Molecular Genetics of Secondary Chemistry in Metarhizium Fungi. In Advances in Genetics. (Ed.^(Eds Brian L and Raymond JSL) pp. 365-436. (Academic Press). //www.sciencedirect.com/science/article/pii/S0065266016300050

Duchęne D and Bochot A (2016) Thirty years with cyclodextrins. International Journal of Pharmaceutics 514, 58-72. //www.sciencedirect.com/science/article/pii/S0378517316306603

Dunn CJ and Bailey JD (2016) Tree mortality and structural change following mixed-severity fire in Pseudotsuga forests of Oregon’s western Cascades, USA. Forest Ecology and Management 365, 107-118. //www.sciencedirect.com/science/article/pii/S0378112716000402

Erdoğar N, Esendağlı G, Nielsen TT, Şen M, Öner L and Bilensoy E (2016) Design and optimization of novel paclitaxel-loaded folate-conjugated amphiphilic cyclodextrin nanoparticles. International Journal of Pharmaceutics 509, 375-390. //www.sciencedirect.com/science/article/pii/S0378517316304215

Erfani M, Shabani Z, Shamsaei M, Shirmardi SP and Shafiei M (2016) 99mTc-tricarbonyl labeling of paclitaxel as an antimicrotubule agent and its evaluation in B16-F10 melanoma tumor-bearing mice. Journal of Labelled Compounds and Radiopharmaceuticals 59, 582-588. http://dx.doi.org/10.1002/jlcr.3468

Esfandyari-Manesh M, Darvishi B, Ishkuh FA, Shahmoradi E, Mohammadi A, Javanbakht M, Dinarvand R and Atyabi F (2016) Paclitaxel molecularly imprinted polymer-PEG-folate nanoparticles for targeting anticancer delivery: Characterization and cellular cytotoxicity. Materials Science and Engineering: C 62, 626-633. //www.sciencedirect.com/science/article/pii/S0928493116300583

Feng S, Chen K, Wang C, Jiang X, Dong H, Gong Z and Liu K (2016) Design, synthesis, and evaluation of water-soluble morpholino-decorated paclitaxel prodrugs with remarkably decreased toxicity. Bioorganic & Medicinal Chemistry Letters 26, 3598-3602. //www.sciencedirect.com/science/article/pii/S0960894X16306230

Firempong CK, Zhang HY, Wang Y, Chen J, Cao X, Deng W, Zhou J, Wang Q, Tong S-S, Yu J and Xu X (2016) Segetoside I, a plant-derived bisdesmosidic saponin, induces apoptosis in human hepatoma cells in vitro and inhibits tumor growth in vivo. Pharmacological Research 110, 101-110. //www.sciencedirect.com/science/article/pii/S1043661816304030

Fischer DG, Antos JA, Grandy WG and Zobel DB (2016) A little disturbance goes a long way: 33-year understory successional responses to a thin tephra deposit. Forest Ecology and Management 382, 236-243. //www.sciencedirect.com/science/article/pii/S0378112716307630

Foureau E, Carqueijeiro I, Dugé de Bernonville T, Melin C, Lafontaine F, Besseau S, Lanoue A, Papon N, Oudin A, Glévarec G, Clastre M, St-Pierre B, Giglioli-Guivarc’h N and Courdavault V (2016) Chapter Eight - Prequels to Synthetic Biology: From Candidate Gene Identification and Validation to Enzyme Subcellular Localization in Plant and Yeast Cells. In Methods in Enzymology. (Ed.^(Eds Sarah EOC) pp. 167-206. (Academic Press). //www.sciencedirect.com/science/article/pii/S0076687916000975

García-Varela R, Fajardo Ramírez OR, Serna-Saldivar SO, Altamirano J and Cardineau GA (2016) Cancer cell specific cytotoxic effect of Rhoeo discolor extracts and solvent fractions. Journal of Ethnopharmacology 190, 46-58. //www.sciencedirect.com/science/article/pii/S0378874116303348

Guerreiro DD, Lima LFd, Rodrigues GQ, Carvalho AdA, Castro SV, Campello CC, Pessoa CdÓ, Gadelha CRF, Figueiredo JRd, Bordignon V and Rodrigues APR (2016) In situ cultured preantral follicles is a useful model to evaluate the effect of anticancer drugs on caprine folliculogenesis. Microscopy Research and Technique 79, 773-781. http://dx.doi.org/10.1002/jemt.22697

Gupta R and Bhaskar A (2016) Chemotherapy-induced peripheral neuropathic pain. BJA Education 16, 115-119. http://bjaed.oxfordjournals.org

Gurung AB, Bhattacharjee A and Ali MA (2016) Exploring the physicochemical profile and the binding patterns of selected novel anticancer Himalayan plant derived active compounds with macromolecular targets. Informatics in Medicine Unlocked 5, 1-14. //www.sciencedirect.com/science/article/pii/S2352914816300235

Habib A and Finn AV (2016) Antiproliferative Drugs for Restenosis Prevention. Interventional Cardiology Clinics 5, 321-329. //www.sciencedirect.com/science/article/pii/S2211745816300189

Han R, Rai A, Nakamura M, Suzuki H, Takahashi H, Yamazaki M and Saito K (2016) Chapter Two - De Novo Deep Transcriptome Analysis of Medicinal Plants for Gene Discovery in Biosynthesis of Plant Natural Products. In Methods in Enzymology. (Ed.^(Eds Sarah EOC) pp. 19-45. (Academic Press). //www.sciencedirect.com/science/article/pii/S0076687916001130

Haq I, Salvi S, Brown L, Rennie I and Rundle P (2016) Docetaxel maculopathy. Cancer Treatment Communications 7, 4-7. //www.sciencedirect.com/science/article/pii/S2213089615300165

Hardcastle IR (2016) Protein–Protein Interaction Inhibitors in Cancer. In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780124095472123923

He B, Lu C, Zheng G, He X, Wang M, Chen G, Zhang G and Lu A (2016) Combination therapeutics in complex diseases. Journal of Cellular and Molecular Medicine 20, 2231-2240. http://dx.doi.org/10.1111/jcmm.12930

Heller L, Knorrscheidt A, Flemming F, Wiemann J, Sommerwerk S, Pavel IZ, Al-Harrasi A and Csuk R (2016) Synthesis and proapoptotic activity of oleanolic acid derived amides. Bioorganic Chemistry 68, 137-151. //www.sciencedirect.com/science/article/pii/S0045206816300797

Hiebert-Giesbrecht MR, Escalante-Erosa F, García-Sosa K, Dzib GR, Calvo-Irabien LM and Peńa-Rodríguez LM (2016) Spatio-Temporal Variation of Terpenoids in Wild Plants of Pentalinon andrieuxii. Chemistry & Biodiversity 13, 1521-1526. http://dx.doi.org/10.1002/cbdv.201600085

Hossen MJ, Kim M-Y, Kim J-H and Cho JY (2016) Codonopsis lanceolata: A Review of Its Therapeutic Potentials. Phytotherapy Research 30, 347-356. http://dx.doi.org/10.1002/ptr.5553

Hou J, Sun E, Sun C, Wang J, Yang L, Jia X-b and Zhang Z-h (2016) Improved oral bioavailability and anticancer efficacy on breast cancer of paclitaxel via Novel Soluplus®—Solutol® HS15 binary mixed micelles system. International Journal of Pharmaceutics 512, 186-193. //www.sciencedirect.com/science/article/pii/S0378517316307955

Hu Q, Sun W, Wang C and Gu Z (2016) Recent advances of cocktail chemotherapy by combination drug delivery systems. Advanced Drug Delivery Reviews 98, 19-34. //www.sciencedirect.com/science/article/pii/S0169409X15002471

Jacobo-Herrera NJ, Jacobo-Herrera FE, Zentella-Dehesa A, Andrade-Cetto A, Heinrich M and Pérez-Plasencia C (2016) Medicinal plants used in Mexican traditional medicine for the treatment of colorectal cancer. Journal of Ethnopharmacology 179, 391-402. //www.sciencedirect.com/science/article/pii/S0378874115302968

Jafri L, Saleem S, Kondrytuk TP, Haq I-u, Ullah N, Pezzuto JM and Mirza B (2016) Hedera nepalensis K. Koch: A Novel Source of Natural Cancer Chemopreventive and Anticancerous Compounds. Phytotherapy Research 30, 447-453. http://dx.doi.org/10.1002/ptr.5546

Jeandet P, Clément C, Tisserant L-P, Crouzet J and Courot É (2016) Use of grapevine cell cultures for the production of phytostilbenes of cosmetic interest. Comptes Rendus Chimie 19, 1062-1070. //www.sciencedirect.com/science/article/pii/S1631074816000758

Jiang Y, Meng X, Wu Z and Qi X (2016) Modified chitosan thermosensitive hydrogel enables sustained and efficient anti-tumor therapy via intratumoral injection. Carbohydrate Polymers 144, 245-253. //www.sciencedirect.com/science/article/pii/S0144861716301242

Jiménez-Santos JL, González-Vela JL, Villarreal G and González-Guerrero JF (2016) Docetaxel en cáncer de mama metastásico multitratado. Gaceta Mexicana de Oncología 15, 332-335. //www.sciencedirect.com/science/article/pii/S1665920116300852

Kaur S, Kumar M and Kaur S (2016) Chapter 5 - Role of Phytochemicals in MAPK Signaling Pathway-Mediated Apoptosis: A Possible Strategy in Cancer Chemoprevention. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 159-178. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444637499000050

Kawai S, Sasaki H, Okada N, Kanie K, Yokoshima S, Fukuyama T, Honda H and Kato R (2016) Morphological Evaluation of Nonlabeled Cells to Detect Stimulation of Nerve Growth Factor Expression by Lyconadin B. J Biomol Screen 21, 795-803. http://jbx.sagepub.com/cgi/content/abstract/21/8/795

Khan I, Iqbal Z, Khan A, Hassan M, Nasir F, Raza A, Ahmad L, Khan A and Akhlaq Mughal M (2016) A simple, rapid and sensitive RP-HPLC-UV method for the simultaneous determination of sorafenib &amp; paclitaxel in plasma and pharmaceutical dosage forms: Application to pharmacokinetic study. Journal of Chromatography B 1033–1034, 261-270. //www.sciencedirect.com/science/article/pii/S1570023216306511

Kim JC, Kim KS, Kim DS, Jin SG, Kim DW, Kim YI, Park J-H, Kim JO, Yong CS, Youn YS, Woo JS and Choi H-G (2016) Effect of HM30181 mesylate salt-loaded microcapsules on the oral absorption of paclitaxel as a novel P-glycoprotein inhibitor. International Journal of Pharmaceutics 506, 93-101. //www.sciencedirect.com/science/article/pii/S0378517316303180

Kinter LB and DeGeorge JJ (2016) Scientific Knowledge and Technology, Animal Experimentation, and Pharmaceutical Development. ILAR J 57, 101-108. http://ilarjournal.oxfordjournals.org/cgi/content/abstract/57/2/101

Kulkarni YA, Garud MS, Gaud RS and Gaikwad AB (2016) Chapter 24 - Recent developments in using plant-derived natural products as tubulin inhibitors for the management of cancer A2 - Watson, Ronald Ross. In Fruits, Vegetables, and Herbs. (Ed.^(Eds Preedy VR) pp. 507-524. (Academic Press). //www.sciencedirect.com/science/article/pii/B978012802972500024X

Lacourse T, Beer KW and Hoffman EH (2016) Identification of conifer stomata in pollen samples from western North America. Review of Palaeobotany and Palynology 232, 140-150. //www.sciencedirect.com/science/article/pii/S0034666715300324

Lanza K and Stone Jr B (2016) Climate adaptation in cities: What trees are suitable for urban heat management? Landscape and Urban Planning 153, 74-82. //www.sciencedirect.com/science/article/pii/S0169204615002443

Lee D, Kim IY, Saha S and Choi KS (2016) Paraptosis in the anti-cancer arsenal of natural products. Pharmacology & Therapeutics 162, 120-133. //www.sciencedirect.com/science/article/pii/S0163725816000048

Lee H-E, Nam J-S, Shin J-A, Hong I-S, Yang I-H, You M-J and Cho S-D (2016) Convallaria keiskei as a novel therapeutic alternative for salivary gland cancer treatment by targeting myeloid cell leukemia-1. Head & Neck 38, E761-E770. http://dx.doi.org/10.1002/hed.24096

Leopold EB, Dunwiddie PW, Whitlock C, Nickmann R and Watts WA (2016) Postglacial vegetation history of Orcas Island, northwestern Washington. Quaternary Research 85, 380-390. //www.sciencedirect.com/science/article/pii/S0033589416000181

Li D, Cao Z, Liao X, Yang P and Liu L (2016) The development of a quantitative and qualitative method based on UHPLC-QTOF MS/MS for evaluation paclitaxel–tetrandrine interaction and its application to a pharmacokinetic study. Talanta 160, 256-267. //www.sciencedirect.com/science/article/pii/S0039914016305148

Li R (2016) Marinopyrroles: Unique Drug Discoveries Based on Marine Natural Products. Medicinal Research Reviews 36, 169-189. http://dx.doi.org/10.1002/med.21359

Li Y, He H, Wang Q and Tang X (2016) Preparation, stability and pharmacokinetics evaluation of lipid microspheres loading a promising antitumor candidate, Timataxel. Asian Journal of Pharmaceutical Sciences 11, 771-779. //www.sciencedirect.com/science/article/pii/S181808761630054X

Lim S-L and Mohamed S (2016) Functional food and dietary supplements for lung health. Trends in Food Science & Technology 57, Part A, 74-82. //www.sciencedirect.com/science/article/pii/S0924224416303478

Lintz HE, Gray AN, Yost A, Sniezko R, Woodall C, Reilly M, Hutten K and Elliott M (2016) Quantifying density-independent mortality of temperate tree species. Ecological Indicators 66, 1-9. //www.sciencedirect.com/science/article/pii/S1470160X15006433

Ma H, Chen G, Wang T, Li Q and Liu Y (2016) Design, Synthesis, and Biological Evaluation of a Novel Water-soluble Prodrug of Docetaxel with Amino Acid as a Linker. Chemical Biology & Drug Design 88, 363-369. http://dx.doi.org/10.1111/cbdd.12762

Mady MS, Mohyeldin MM, Ebrahim HY, Elsayed HE, Houssen WE, Haggag EG, Soliman RF and El Sayed KA (2016) The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation, migration and invasion. Bioorganic & Medicinal Chemistry 24, 113-122. //www.sciencedirect.com/science/article/pii/S0968089615301619

Magdy T, Burmeister BT and Burridge PW (2016) Validating the pharmacogenomics of chemotherapy-induced cardiotoxicity: What is missing? Pharmacology & Therapeutics 168, 113-125. //www.sciencedirect.com/science/article/pii/S0163725816301656

McGonigle IV (2016) Patenting nature or protecting culture? Ethnopharmacology and indigenous intellectual property rights. J Law Biosci 3, 217-226. http://jlb.oxfordjournals.org/cgi/content/abstract/3/1/217

Muńoz Cendales DR and Cuca Suárez LE (2016) Compuestos citotóxicos de origen vegetal y su relación con proteínas inhibidoras de apoptosis (IAP). Revista Colombiana de Cancerología 20, 124-134. //www.sciencedirect.com/science/article/pii/S0123901516300038

Mutlu EC, Bostan MS, Bahadori F, Kocyigit A, Oner ET and Eroglu MS (2016) Lecithin-acrylamido-2-methylpropane sulfonate based crosslinked phospholipid nanoparticles as drug carrier. Journal of Applied Polymer Science 133, n/a-n/a. http://dx.doi.org/10.1002/app.44105

Nabors LB, Surboeck B and Grisold W (2016) Chapter 14 - Complications from pharmacotherapy. In Handbook of Clinical Neurology. (Ed.^(Eds Mitchel SB and Michael W) pp. 235-250. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780128029978000141

Němcová-Fürstová V, Kopperová D, Balušíková K, Ehrlichová M, Brynychová V, Václavíková R, Daniel P, Souček P and Kovář J (2016) Characterization of acquired paclitaxel resistance of breast cancer cells and involvement of ABC transporters. Toxicology and Applied Pharmacology 310, 215-228. //www.sciencedirect.com/science/article/pii/S0041008X16302861

Nho KJ, Chun JM and Kim HK (2016) Induction of mitochondria-dependent apoptosis in HepG2 human hepatocellular carcinoma cells by timosaponin A-III. Environmental Toxicology and Pharmacology 45, 295-301. //www.sciencedirect.com/science/article/pii/S1382668916301508

Nian S, Liu E, Fan Y, Alolga RN, Li H and Li P (2016) Orthogonal separation protocol for the simultaneous preparation of four medically active compounds from Anemarrhenae Rhizoma by sequential polyamide and macroporous resin adsorbent chromatography. Journal of Separation Science 39, 3195-3204. http://dx.doi.org/10.1002/jssc.201600274

Ning P, Zhong J-g, Jiang F, Zhang Y, Zhao J, Tian F and Li W (2016) Role of protein S in castration-resistant prostate cancer-like cells. Endocr. Relat. Cancer 23, 595-607. http://erc.endocrinology-journals.org/cgi/content/abstract/23/8/595

Noreen H, Farman M and McCullagh JSO (2016) Bioassay-guided isolation of cytotoxic flavonoids from aerial parts of Coronopus didymus. Journal of Ethnopharmacology 194, 971-980. //www.sciencedirect.com/science/article/pii/S037887411631529X

Omosa LK, Midiwo JO, Masila VM, Gisacho BM, Munayi R, Francisca K, Chemutai KP, Elhaboob G, Saeed MEM, Hamdoun S, Kuete V and Efferth T (2016) Cytotoxicity of 91 Kenyan indigenous medicinal plants towards human CCRF-CEM leukemia cells. Journal of Ethnopharmacology 179, 177-196. //www.sciencedirect.com/science/article/pii/S0378874115302798

Pal MK, Jaiswar SP, Srivastav AK, Goyal S, Dwivedi A, Verma A, Singh J, Pathak AK, Sankhwar PL and Ray RS (2016) Synergistic effect of piperine and paclitaxel on cell fate via cyt-c, Bax/Bcl-2-caspase-3 pathway in ovarian adenocarcinomas SKOV-3 cells. European Journal of Pharmacology 791, 751-762. //www.sciencedirect.com/science/article/pii/S0014299916306586

Patil RH, Patil MP and Maheshwari VL (2016) Chapter 5 - Bioactive Secondary Metabolites From Endophytic Fungi: A Review of Biotechnological Production and Their Potential Applications. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 189-205. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444636010000053

Perry TD and Jones JA (2016) Summer streamflow deficits from regenerating Douglas-fir forest in the Pacific Northwest, USA. Ecohydrology, n/a-n/a. http://dx.doi.org/10.1002/eco.1790

Petta I, Lievens S, Libert C, Tavernier J and De Bosscher K (2016) Modulation of Protein–Protein Interactions for the Development of Novel Therapeutics. Molecular Therapy 24, 707-718. //www.sciencedirect.com/science/article/pii/S1525001616309947

Pons DG, Nadal-Serrano M, Torrens-Mas M, Oliver J and Roca P (2016) The Phytoestrogen Genistein Affects Breast Cancer Cells Treatment Depending on the ERα/ERβ Ratio. Journal of Cellular Biochemistry 117, 218-229. http://dx.doi.org/10.1002/jcb.25268

Qazzaz ME, Raja VJ, Lim K-H, Kam T-S, Lee JB, Gershkovich P and Bradshaw TD (2016) In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B. Cancer Letters 370, 185-197. //www.sciencedirect.com/science/article/pii/S0304383515006448

Rastogi S, Pandey MM and Rawat AKS (2016) Traditional herbs: a remedy for cardiovascular disorders. Phytomedicine 23, 1082-1089. //www.sciencedirect.com/science/article/pii/S0944711315003311

Rengarajan T and Yaacob NS (2016) The flavonoid fisetin as an anticancer agent targeting the growth signaling pathways. European Journal of Pharmacology 789, 8-16. //www.sciencedirect.com/science/article/pii/S0014299916304319

Risuleo G (2016) Chapter 33 - Resveratrol: Multiple Activities on the Biological Functionality of the Cell A2 - Gupta, Ramesh C. In Nutraceuticals. (Ed.^(Eds  pp. 453-464. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128021477000334

Sachdev JC and Jahanzeb M (2016) Use of Cytotoxic Chemotherapy in Metastatic Breast Cancer: Putting Taxanes in Perspective. Clinical Breast Cancer 16, 73-81. //www.sciencedirect.com/science/article/pii/S1526820915002189

Safe S and Kasiappan R (2016) Natural Products as Mechanism-based Anticancer Agents: Sp Transcription Factors as Targets. Phytotherapy Research 30, 1723-1732. http://dx.doi.org/10.1002/ptr.5669

Sattarahmady N, Azarpira N, Hosseinpour A, Heli H and Zare T (2016) Albumin coated arginine-capped magnetite nanoparticles as a paclitaxel vehicle: Physicochemical characterizations and in vitro evaluation. Journal of Drug Delivery Science and Technology 36, 68-74. //www.sciencedirect.com/science/article/pii/S1773224716301253

Schläger S and Dräger B (2016) Exploiting plant alkaloids. Current Opinion in Biotechnology 37, 155-164. //www.sciencedirect.com/science/article/pii/S0958166915001664

Schrepfer P, Buettner A, Goerner C, Hertel M, van Rijn J, Wallrapp F, Eisenreich W, Sieber V, Kourist R, Bru, #x and ck T (2016) Identification of amino acid networks governing catalysis in the closed complex of class I terpene synthases. PNAS 113, E958-967. http://www.pnas.org/cgi/content/abstract/113/8/E958

Sharma N, Madan P and Lin S (2016) Effect of process and formulation variables on the preparation of parenteral paclitaxel-loaded biodegradable polymeric nanoparticles: A co-surfactant study. Asian Journal of Pharmaceutical Sciences 11, 404-416. //www.sciencedirect.com/science/article/pii/S1818087615000896

Singh B and Kaur A (2016) Antidiabetic potential of a peptide isolated from an endophytic Aspergillus awamori. Journal of Applied Microbiology 120, 301-311. http://dx.doi.org/10.1111/jam.12998

Spreen MI, Martens JM, Hansen BE, Knippenberg B, Verhey E, van Dijk LC, de Vries J-PPM, Vos J-A, de Borst GJ, Vonken E-JPA, Wever JJ, Statius van Eps RG, Mali WPTM and van Overhagen H (2016) Percutaneous Transluminal Angioplasty and Drug-Eluting Stents for Infrapopliteal Lesions in Critical Limb Ischemia (PADI) Trial. Circ Cardiovasc Interv 9, e002376-. http://circinterventions.ahajournals.org/cgi/content/abstract/9/2/e002376

Sukhorukov AY, Sukhanova AA and Zlotin SG (2016) Stereoselective reactions of nitro compounds in the synthesis of natural compound analogs and active pharmaceutical ingredients. Tetrahedron 72, 6191-6281. //www.sciencedirect.com/science/article/pii/S0040402016307256

Swaminathan S, Cavalli R and Trotta F (2016) Cyclodextrin-based nanosponges: a versatile platform for cancer nanotherapeutics development. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 8, 579-601. http://dx.doi.org/10.1002/wnan.1384

Taleb RI, Najm P, Shebaby W, Boulos JC, Demirdjian S, Hariri E, El-Sibai M, Daher C and Mroueh M (2016) β-2-himachalen-6-ol: A novel anticancer sesquiterpene unique to the Lebanese wild carrot. Journal of Ethnopharmacology 190, 59-67. //www.sciencedirect.com/science/article/pii/S0378874116303336

Tan G-Y, Zhu F, Deng Z and Liu T (2016) In vitro reconstitution guide for targeted synthetic metabolism of chemicals, nutraceuticals and drug precursors. Synthetic and Systems Biotechnology 1, 25-33. //www.sciencedirect.com/science/article/pii/S2405805X1530003X

Tanaka M, Kuriyama S, Itoh G, Kohyama A, Iwabuchi Y, Shibata H, Yashiro M and Aiba N (2016) Identification of anti-cancer chemical compounds using Xenopus embryos. Cancer Science 107, 803-811. http://dx.doi.org/10.1111/cas.12940

Tanamatayarat P (2016) Antityrosinase, antioxidative activities, and brine shrimp lethality of ethanolic extracts from Protium serratum (Wall. ex Colebr.) Engl. Asian Pacific Journal of Tropical Biomedicine 6, 1050-1055. //www.sciencedirect.com/science/article/pii/S2221169116300764

Tang M-L, Zhou L, Chang J, Hu Z-H, Qin Y and Sun X (2016) Differential metabolism of 3FDT and docetaxel in RLMs, rats, and HLMs. European Journal of Medicinal Chemistry 113, 81-91. //www.sciencedirect.com/science/article/pii/S0223523416300769

Tanney JB, McMullin DR, Green BD, Miller JD and Seifert KA (2016) Production of antifungal and antiinsectan metabolites by the Picea endophyte Diaporthe maritima sp. nov. Fungal Biology 120, 1448-1457. //www.sciencedirect.com/science/article/pii/S1878614616300496

Toogood HS, Tait S, Jervis A, Ní Cheallaigh A, Humphreys L, Takano E, Gardiner JM and Scrutton NS (2016) Chapter Eleven - Natural Product Biosynthesis in Escherichia coli: Mentha Monoterpenoids. In Methods in Enzymology. (Ed.^(Eds Sarah EOC) pp. 247-270. (Academic Press). //www.sciencedirect.com/science/article/pii/S007668791600104X

Torrens-Spence MP, Fallon TR and Weng JK (2016) Chapter Four - A Workflow for Studying Specialized Metabolism in Nonmodel Eukaryotic Organisms. In Methods in Enzymology. (Ed.^(Eds Sarah EOC) pp. 69-97. (Academic Press). //www.sciencedirect.com/science/article/pii/S0076687916001270

Tyihák E and Móricz ÁM (2016) Chapter 7 - BioArena system for studying key molecules as well as ingredients in biological samples. In Forced-Flow Layer Chromatography. (Ed.^(Eds  pp. 397-485. (Elsevier: Boston). //www.sciencedirect.com/science/article/pii/B9780124201613000071

Ullah N, Nadhman A, Siddiq S, Mehwish S, Islam A, Jafri L and Hamayun M (2016) Plants as Antileishmanial Agents: Current Scenario. Phytotherapy Research 30, 1905-1925. http://dx.doi.org/10.1002/ptr.5710

Vardanyan R and Hruby V (2016) Chapter 28 - Antineoplastic Agents. In Synthesis of Best-Seller Drugs. (Ed.^(Eds  pp. 495-547. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780124114920000286

Villaruz LC and Socinski MA (2016) Is there a role of nab-paclitaxel in the treatment of advanced non-small cell lung cancer? The data suggest yes. European Journal of Cancer 56, 162-171. //www.sciencedirect.com/science/article/pii/S0959804915011788

Wahid M, Mandal RK, Dar SA, Jawed A, Lohani M, Areeshi MY, Akhter N and Haque S (2016) Therapeutic potential and critical analysis of trastuzumab and bevacizumab in combination with different chemotherapeutic agents against metastatic breast/colorectal cancer affecting various endpoints. Critical Reviews in Oncology/Hematology 104, 124-130. //www.sciencedirect.com/science/article/pii/S1040842816301421

Wink M (2016) Alkaloids: Toxicology and Health Effects. In Encyclopedia of Food and Health. (Ed.^(Eds  pp. 106-114. (Academic Press: Oxford). //www.sciencedirect.com/science/article/pii/B9780123849472000209

Winkelmann RR, Yiannias JA, DiCaudo DJ, Trotter SC, Farhey Y, Griffing WL, Martorano LM and Winkelmann JC (2016) Paclitaxel-induced diffuse cutaneous sclerosis: a case with associated esophageal dysmotility, Raynauds phenomenon, and myositis. International Journal of Dermatology 55, 97-100. http://dx.doi.org/10.1111/ijd.12437

Wong VK-W, Law BY-K, Yao X-J, Chen X, Xu SW, Liu L and Leung EL-H (2016) Advanced research technology for discovery of new effective compounds from Chinese herbal medicine and their molecular targets. Pharmacological Research 111, 546-555. //www.sciencedirect.com/science/article/pii/S1043661816305357

Wu Y-L, Wang H, Qiu Y-K, Liow SS, Li Z and Loh XJ (2016) PHB-Based Gels as Delivery Agents of Chemotherapeutics for the Effective Shrinkage of Tumors. Advanced Healthcare Materials 5, 2679-2685. http://dx.doi.org/10.1002/adhm.201600723

Xia X, Song X, Xu J, He J, Peng J, Zhang X, Jin D, Abliz Z and Liu Y (2016) Development of a validated LC–APCI-MS/MS method to study the plasma and tumor distribution of CHO-PTX intravenous lipid emulsion. Journal of Pharmaceutical and Biomedical Analysis 117, 532-543. //www.sciencedirect.com/science/article/pii/S0731708515300042

Xiang L, Gong S, Yang L, Hao J, Xue M, Zeng F, Zhang X, Shi W, Wang H and Yu D (2016) Biocontrol potential of endophytic fungi in medicinal plants from Wuhan Botanical Garden in China. Biological Control 94, 47-55. //www.sciencedirect.com/science/article/pii/S104996441530058X

Xie J, Yang Z, Zhou C, Zhu J, Lee RJ and Teng L (2016) Nanotechnology for the delivery of phytochemicals in cancer therapy. Biotechnology Advances 34, 343-353. //www.sciencedirect.com/science/article/pii/S0734975016300453

Xu D, Zhang B-Y and Yang X-L (2016) Antifungal Monoterpene Derivatives from the Plant Endophytic Fungus Pestalotiopsis foedan. Chemistry & Biodiversity 13, 1422-1425. http://dx.doi.org/10.1002/cbdv.201600114

Yeh C-W, Kan S-C, Lin C-C, Shieh C-J and Liu Y-C (2016) Polyhydroxylated steroids and triterpenoids from an entophytic fungus, Hypocreales sp. NCHU01 isolated from Tuber magnatum. Journal of the Taiwan Institute of Chemical Engineers 64, 22-30. //www.sciencedirect.com/science/article/pii/S1876107016300438

Yeo SK, Ali AY, Hayward OA, Turnham D, Jackson T, Bowen ID and Clarkson R (2016) β-Bisabolene, a Sesquiterpene from the Essential Oil Extract of Opoponax (Commiphora guidottii), Exhibits Cytotoxicity in Breast Cancer Cell Lines. Phytotherapy Research 30, 418-425. http://dx.doi.org/10.1002/ptr.5543

Zhao D, Zhang H, Yang S, He W and Luan Y (2016) Redox-sensitive mPEG-SS-PTX/TPGS mixed micelles: An efficient drug delivery system for overcoming multidrug resistance. International Journal of Pharmaceutics 515, 281-292. //www.sciencedirect.com/science/article/pii/S0378517316309632

Zhao Y, Mu X and Du G (2016) Microtubule-stabilizing agents: New drug discovery and cancer therapy. Pharmacology & Therapeutics 162, 134-143. //www.sciencedirect.com/science/article/pii/S0163725815002326

Zheng W, Komatsu S, Zhu W, Zhang L, Li X, Cui L and Tian J (2016) Response and Defense Mechanisms of Taxus chinensis Leaves Under UV-A Radiation are Revealed Using Comparative Proteomics and Metabolomics Analyses. Plant Cell Physiol. 57, 1839-1853. http://pcp.oxfordjournals.org/cgi/content/abstract/57/9/1839

(2015) Preface. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. xiii-xiv. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444634627000154

(2015) PM 7/123 (1) Phytophthora lateralis. EPPO Bulletin 45, 397-409. http://dx.doi.org/10.1111/epp.12250

Acker SA, Boetsch JR, Bivin M, Whiteaker L, Cole C and Philippi T (2015) Recent tree mortality and recruitment in mature and old-growth forests in western Washington. Forest Ecology and Management 336, 109-118. //www.sciencedirect.com/science/article/pii/S0378112714005908

Aloysius H and Hu L (2015) Targeted Prodrug Approaches for Hormone Refractory Prostate Cancer. Medicinal Research Reviews 35, 554-585. http://dx.doi.org/10.1002/med.21333

Atanasov AG, Waltenberger B, Pferschy-Wenzig E-M, Linder T, Wawrosch C, Uhrin P, Temml V, Wang L, Schwaiger S, Heiss EH, Rollinger JM, Schuster D, Breuss JM, Bochkov V, Mihovilovic MD, Kopp B, Bauer R, Dirsch VM and Stuppner H (2015) Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnology Advances 33, 1582-1614. //www.sciencedirect.com/science/article/pii/S0734975015300276

Avendańo C and Menéndez JC (2015) Chapter 9 - Anticancer Drugs Targeting Tubulin and Microtubules. In Medicinal Chemistry of Anticancer Drugs (Second Edition). (Ed.^(Eds  pp. 359-390. (Elsevier: Boston). //www.sciencedirect.com/science/article/pii/B9780444626493000090

Azzarito T, Venturi G, Cesolini A and Fais S (2015) Lansoprazole induces sensitivity to suboptimal doses of paclitaxel in human melanoma. Cancer Letters 356, 697-703. //www.sciencedirect.com/science/article/pii/S0304383514006168

Bathaie SZ, Faridi N, Nasimian A, Heidarzadeh H and Tamanoi F (2015) Chapter One - How Phytochemicals Prevent Chemical Carcinogens and/or Suppress Tumor Growth? In The Enzymes. (Ed.^(Eds Bathaie SZ and Fuyuhiko T) pp. 1-42. (Academic Press). //www.sciencedirect.com/science/article/pii/S1874604715000098

Bernabé-Antonio A, Álvarez L, Salcedo-Pérez E, Toral FAL-D, Anzaldo-Hernández J and Cruz-Sosa F (2015) Fatty acid profile of intact plants of two different sites and callus cultures derived from seed and leaf explants of Calophyllum brasiliense Cambess: A new resource of non-edible oil. Industrial Crops and Products 77, 1014-1019. //www.sciencedirect.com/science/article/pii/S0926669015304490

Blaschke M, McKinnon R, Nguyen CH, Holzner S, Zehl M, Atanasov AG, Schelch K, Krieger S, Diaz R, Frisch R, Feistel B, Jäger W, Ecker GF, Dirsch VM, Grusch M, Zupko I, Urban E, Kopp B and Krupitza G (2015) A eudesmane-type sesquiterpene isolated from Pluchea odorata (L.) Cass. combats three hallmarks of cancer cells: Unrestricted proliferation, escape from apoptosis and early metastatic outgrowth in vitro. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 777, 79-90. //www.sciencedirect.com/science/article/pii/S0027510715001050

Calleja P, Espuelas S, Vauthier C, Ponchel G and Irache JM (2015) Controlled Release, Intestinal Transport, and Oral Bioavailablity of Paclitaxel Can be Considerably Increased Using Suitably Tailored Pegylated Poly(Anhydride) Nanoparticles. Journal of Pharmaceutical Sciences 104, 2877-2886. //www.sciencedirect.com/science/article/pii/S0022354916300673

Cariati M, Bains SK, Grootendorst MR, Suyoi A, Peters AM, Mortimer P, Ellis P, Harries M, Van Hemelrijck M and Purushotham AD (2015) Adjuvant taxanes and the development of breast cancer-related arm lymphoedema. British Journal of Surgery 102, 1071-1078. http://dx.doi.org/10.1002/bjs.9846

Castells MC (2015) Anaphylaxis to Chemotherapy and Monoclonal Antibodies. Immunology and Allergy Clinics of North America 35, 335-348. //www.sciencedirect.com/science/article/pii/S0889856115000120

Chapman BR and Bolen EG (2015) Temperate Rain Forest. In Ecology of North America. (Ed.^(Eds  pp. 203-222. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118971550.ch10

Chen J, Dong T, Duan B, Korpelainen H, Niinemets Ü and Li C (2015) Sexual competition and N supply interactively affect the dimorphism and competiveness of opposite sexes in Populus cathayana. Plant, Cell & Environment 38, 1285-1298. http://dx.doi.org/10.1111/pce.12477

Chen L, Wei D, Zhang Q, Yu X, Wang Y and Zhu X (2015) Orotidine 5′-phosphate decarboxylase-based reusable in situ genetic editing system: Development and application in taxol-producing Pestalotiopsis microspora. Engineering in Life Sciences 15, 542-549. http://dx.doi.org/10.1002/elsc.201400220

Chen L-H, Sun Y-T, Chen Y-F, Lee M-Y, Chang L-Y, Chang J-Y and Shen M-R (2015) Integrating Image-Based High-Content Screening with Mouse Models Identifies 5-Hydroxydecanoate as a Neuroprotective Drug for Paclitaxel-Induced Neuropathy. Mol. Cancer Ther. 14, 2206-2214. http://mct.aacrjournals.org/cgi/content/abstract/14/10/2206

Chen S, Liu Z, Li H, Xia G, Lu Y, He L, Huang S and She Z (2015) β-Resorcylic acid derivatives with α-glucosidase inhibitory activity from Lasiodiplodia sp. ZJ-HQ1, an endophytic fungus in the medicinal plant Acanthus ilicifolius. Phytochemistry Letters 13, 141-146. //www.sciencedirect.com/science/article/pii/S1874390015001160

CHUEH F-S, LIN J-J, LIN J-P, YU F-S, LIN J-H, MA Y-S, HUANG Y-P, LIEN J-C and CHUNG J-G (2015) Crude Extract of Polygonum Cuspidatum Promotes Immune Responses in Leukemic Mice Through Enhancing Phagocytosis of Macrophage and Natural Killer Cell Activities In Vivo. In Vivo 29, 255-261. http://iv.iiarjournals.org/cgi/content/abstract/29/2/255

Crotti S, Posocco B, Marangon E, Nitti D, Toffoli G and Agostini M (2015) Mass spectrometry in the pharmacokinetic studies of anticancer natural products. Mass Spectrometry Reviews, n/a-n/a. http://dx.doi.org/10.1002/mas.21478

Dai Z, Liu Y, Guo J, Huang L and Zhang X (2015) Yeast synthetic biology for high-value metabolites. FEMS Yeast Res 15, 1-b-11. http://femsyr.oxfordjournals.org/cgi/content/abstract/15/1/1-b

Derrick JS and Lim MH (2015) Tools of the Trade: Investigations into Design Strategies of Small Molecules to Target Components in Alzheimers Disease. ChemBioChem 16, 887-898. http://dx.doi.org/10.1002/cbic.201402718

Dupont F and Guignard J-L (2015) 8 - Gymnospermes ou Plantes ŕ ovules nus. In Botanique (16e édition). (Ed.^(Eds  pp. 59-75. (Elsevier Masson: Paris). //www.sciencedirect.com/science/article/pii/B9782294741173000086

Dutra RC, Bicca MA, Segat GC, Silva KABS, Motta EM, Pianowski LF, Costa R and Calixto JB (2015) The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε. Neuroscience 303, 126-137. //www.sciencedirect.com/science/article/pii/S0306452215005928

Eitzel MV, Battles J, York R and de Valpine P (2015) Cant see the trees for the forest: complex factors influence tree survival in a temperate second growth forest. Ecosphere 6, 1-17. http://dx.doi.org/10.1890/ES15-00105.1

Ferreira RJ, Ferreira M-JU and dos Santos DJVA (2015) Reversing cancer multidrug resistance: insights into the efflux by ABC transports from in silico studies. Wiley Interdisciplinary Reviews: Computational Molecular Science 5, 27-55. http://dx.doi.org/10.1002/wcms.1196

Floyd JA, Galperin A and Ratner BD (2015) Drug encapsulated polymeric microspheres for intracranial tumor therapy: A review of the literature. Advanced Drug Delivery Reviews 91, 23-37. //www.sciencedirect.com/science/article/pii/S0169409X15000642

Forró E, Galla Z, Nádasdi Z, Árva J and Fülöp F (2015) Novel chemo-enzymatic route to a key intermediate for the taxol side-chain through enantioselective O-acylation. Unexpected acyl migration. Journal of Molecular Catalysis B: Enzymatic 116, 101-105. //www.sciencedirect.com/science/article/pii/S1381117715000727

Freund JA, Franklin JF and Lutz JA (2015) Structure of early old-growth Douglas-fir forests in the Pacific Northwest. Forest Ecology and Management 335, 11-25. //www.sciencedirect.com/science/article/pii/S037811271400512X

Ganie SH, Upadhyay P, Das S and Prasad Sharma M (2015) Authentication of medicinal plants by DNA markers. Plant Gene 4, 83-99. //www.sciencedirect.com/science/article/pii/S235240731500030X

Ghadari R, Alavi FS and Zahedi M (2015) Evaluation of the effect of the chiral centers of Taxol on binding to β-tubulin: A docking and molecular dynamics simulation study. Computational Biology and Chemistry 56, 33-40. //www.sciencedirect.com/science/article/pii/S1476927115000468

Gottfried K, Klar U, Platzek J and Zorn L (2015) Biocatalysis at Work: Applications in the Development of Sagopilone. ChemMedChem 10, 1240-1248. http://dx.doi.org/10.1002/cmdc.201500138

Gudi G, Krähmer A, Koudous I, Strube J and Schulz H (2015) Infrared and Raman spectroscopic methods for characterization of Taxus baccata L. – Improved taxane isolation by accelerated quality control and process surveillance. Talanta 143, 42-49. //www.sciencedirect.com/science/article/pii/S0039914015003483

Gupta AP, Pandotra P, Kushwaha M, Khan S, Sharma R and Gupta S (2015) Chapter 9 - Alkaloids: A Source of Anticancer Agents from Nature. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 341-445. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444634627000099

Harmon ME and Pabst RJ (2015) Testing predictions of forest succession using long-term measurements: 100 yrs of observations in the Oregon Cascades. Journal of Vegetation Science 26, 722-732. http://dx.doi.org/10.1111/jvs.12273

He Y and Wang ZJ (2015) Nociceptor Beta II, Delta, and Epsilon Isoforms of PKC Differentially Mediate Paclitaxel-Induced Spontaneous and Evoked Pain. J. Neurosci. 35, 4614-4625. http://www.jneurosci.org/cgi/content/abstract/35/11/4614

Hegazy M-EF, Mohamed TA, ElShamy AI, Mohamed A-E-HH, Mahalel UA, Reda EH, Shaheen AM, Tawfik WA, Shahat AA, Shams KA, Abdel-Azim NS and Hammouda FM (2015) Microbial biotransformation as a tool for drug development based on natural products from mevalonic acid pathway: A review. Journal of Advanced Research 6, 17-33. //www.sciencedirect.com/science/article/pii/S2090123214001428

Heredia V, Maggio B, Beltramo DM and Dupuy FG (2015) Interfacial stabilization of the antitumoral drug Paclitaxel in monolayers of GM1 and GD1a gangliosides. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848, 2163-2171. //www.sciencedirect.com/science/article/pii/S0005273615002023

Hirai S, Utsugi M, Iwamoto M and Nakada M (2015) Formal Total Synthesis of (−)-Taxol through Pd-Catalyzed Eight-Membered Carbocyclic Ring Formation. Chemistry – A European Journal 21, 355-359. http://dx.doi.org/10.1002/chem.201404295

Houghton PJ, Kurmasheva RT, Kolb EA, Gorlick R, Maris JM, Wu J, Tong Z, Arnold MA, Chatterjee M, Williams TM and Smith MA (2015) Initial testing (stage 1) of the tubulin binding agent nanoparticle albumin-bound (nab) paclitaxel (Abraxane®) by the Pediatric Preclinical Testing Program (PPTP). Pediatric Blood & Cancer 62, 1214-1221. http://dx.doi.org/10.1002/pbc.25474

Hung F-M, Shang H-S, Tang N-Y, Lin J-J, Lu K-W, Lin J-P, Ko Y-C, Yu C-C, Wang H-L, Liao J-C, Lu H-F and Chung J-G (2015) Effects of diallyl trisulfide on induction of apoptotic death in murine leukemia WEHI-3 cells in vitro and alterations of the immune responses in normal and leukemic mice in vivo. Environmental Toxicology 30, 1343-1353. http://dx.doi.org/10.1002/tox.22005

Ignea C, Trikka FA, Nikolaidis AK, Georgantea P, Ioannou E, Loupassaki S, Kefalas P, Kanellis AK, Roussis V, Makris AM and Kampranis SC (2015) Efficient diterpene production in yeast by engineering Erg20p into a geranylgeranyl diphosphate synthase. Metabolic Engineering 27, 65-75. //www.sciencedirect.com/science/article/pii/S1096717614001384

Ikeda NEA, Novak EM, Maria DA, Velosa AS and Pereira RMS (2015) Synthesis, characterization and biological evaluation of Rutin–zinc(II) flavonoid -metal complex. Chemico-Biological Interactions 239, 184-191. //www.sciencedirect.com/science/article/pii/S0009279715002392

Ilinskaya AN, Clogston JD, McNeil SE and Dobrovolskaia MA (2015) Induction of oxidative stress by Taxol® vehicle Cremophor-EL triggers production of interleukin-8 by peripheral blood mononuclear cells through the mechanism not requiring de novo synthesis of mRNA. Nanomedicine: Nanotechnology, Biology and Medicine 11, 1925-1938. //www.sciencedirect.com/science/article/pii/S1549963415001550

Inada A, Oshima T and Baba Y (2015) Enhancing the water dispersibility of paclitaxel by complexation with hydrophobic peptides. Colloids and Surfaces B: Biointerfaces 135, 408-415. //www.sciencedirect.com/science/article/pii/S0927776515301211

Irwin LL, Rock DF, Rock SC, Loehle C and Van Deusen P (2015) Forest ecosystem restoration: Initial response of spotted owls to partial harvesting. Forest Ecology and Management 354, 232-242. //www.sciencedirect.com/science/article/pii/S0378112715003357

Khanna C, Rosenberg M and Vail DM (2015) A Review of Paclitaxel and Novel Formulations Including Those Suitable for Use in Dogs. Journal of Veterinary Internal Medicine 29, 1006-1012. http://dx.doi.org/10.1111/jvim.12596

Kim J, Doerr M and Kitchell BE (2015) Exploration of paclitaxel (Taxol) as a treatment for malignant tumors in cats: a descriptive case series. Journal of Feline Medicine and Surgery 17, 186-190. http://jfm.sagepub.com/cgi/content/abstract/17/2/186

Kitagawa RR, Vilegas W, Varanda EA and Raddi MSG (2015) Evaluation of mutagenicity and metabolism-mediated cytotoxicity of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin from Paepalanthus latipes. Revista Brasileira de Farmacognosia 25, 16-21. //www.sciencedirect.com/science/article/pii/S0102695X15000320

Kittakoop P (2015) Chapter 5 - Anticancer Drugs and Potential Anticancer Leads Inspired by Natural Products. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 251-307. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444634603000055

Krivoruchko A and Nielsen J (2015) Production of natural products through metabolic engineering of Saccharomyces cerevisiae. Current Opinion in Biotechnology 35, 7-15. //www.sciencedirect.com/science/article/pii/S0958166914002195

Ku MS (2015) Recent trends in specialty pharma business model. Journal of Food and Drug Analysis 23, 595-608. //www.sciencedirect.com/science/article/pii/S1021949815000575

Kundu CN, Das S, Nayak A, Satapathy SR, Das D and Siddharth S (2015) Anti-malarials are anti-cancers and vice versa – One arrow two sparrows. Acta Tropica 149, 113-127. //www.sciencedirect.com/science/article/pii/S0001706X15001175

KUO Y-J, LIN J-P, HSIAO Y-T, CHOU G-L, TSAI Y-H, CHIANG S-Y, LIN J-G and CHUNG J-G (2015) Ethanol Extract of Hedyotis diffusa Willd Affects Immune Responses in Normal Balb/c Mice In Vivo. In Vivo 29, 453-460. http://iv.iiarjournals.org/cgi/content/abstract/29/4/453

Kuzmov A and Minko T (2015) Nanotechnology approaches for inhalation treatment of lung diseases. Journal of Controlled Release 219, 500-518. //www.sciencedirect.com/science/article/pii/S0168365915300377

Laishram S, Moirangthem DS, Borah JC, Pal BC, Suman P, Gupta SK, Kalita MC and Talukdar NC (2015) Chrysin rich Scutellaria discolor Colebr. induces cervical cancer cell death via the induction of cell cycle arrest and caspase-dependent apoptosis. Life Sciences 143, 105-113. //www.sciencedirect.com/science/article/pii/S0024320515300618

Li P, Yang G, Qiu Y, Lin L and Dong F (2015) Paeonol produced by Chaetomium sp., an endophytic fungus isolated from Paeonia suffruticosa. Phytochemistry Letters 13, 334-342. //www.sciencedirect.com/science/article/pii/S1874390015300409

Li Q-F, Lin H-X, Cui Y-M and Xu P-P (2015) Syntheses and biological evaluation of C-3′-N-acyl modified taxane analogues from 1-deoxybaccatin-VI. European Journal of Medicinal Chemistry 104, 97-105. //www.sciencedirect.com/science/article/pii/S0223523415302634

Li Y, Zhao X, Zu Y and Zhang Y (2015) Preparation and characterization of paclitaxel nanosuspension using novel emulsification method by combining high speed homogenizer and high pressure homogenization. International Journal of Pharmaceutics 490, 324-333. //www.sciencedirect.com/science/article/pii/S0378517315004998

Liu Y-Z, Yang C-M, Chen J-Y, Liao J-W and Hu M-L (2015) Alpha-carotene inhibits metastasis in Lewis lung carcinoma in vitro, and suppresses lung metastasis and tumor growth in combination with taxol in tumor xenografted C57BL/6 mice. The Journal of Nutritional Biochemistry 26, 607-615. //www.sciencedirect.com/science/article/pii/S0955286315000285

Ma D-L, Liu L-J, Lin S, Wang M, Chan DS-H and Leung C-H (2015) Chapter 4 - Recent Advances in the Discovery and Development of Protein-Protein Interaction Modulators by Virtual Screening A2 - Ul-Haq, Zaheer. In Frontiers in Computational Chemistry. (Ed.^(Eds Madura JD) pp. 121-157. (Bentham Science Publishers). //www.sciencedirect.com/science/article/pii/B9781608058655500046

Mabeta P and Pepper MS (2015) Altered expression of platelet factor 4 and basic fibroblast growth factor correlates with the inhibition of tumor growth in mice. Biomedicine & Pharmacotherapy 69, 186-190. //www.sciencedirect.com/science/article/pii/S0753332214001796

Manček-Keber M and Jerala R (2015) Postulates for validating TLR4 agonists. European Journal of Immunology 45, 356-370. http://dx.doi.org/10.1002/eji.201444462

Mandal SC, Mandal V and Das AK (2015) Chapter 4 - What All Should Know about Plant Drugs. In Essentials of Botanical Extraction. (Ed.^(Eds  pp. 35-61. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128023259000045

Mao X-M, Xu W, Li D, Yin W-B, Chooi Y-H, Li Y-Q, Tang Y and Hu Y (2015) Epigenetic Genome Mining of an Endophytic Fungus Leads to the Pleiotropic Biosynthesis of Natural Products. Angewandte Chemie 127, 7702-7706. http://dx.doi.org/10.1002/ange.201502452

Mao X-M, Xu W, Li D, Yin W-B, Chooi Y-H, Li Y-Q, Tang Y and Hu Y (2015) Epigenetic Genome Mining of an Endophytic Fungus Leads to the Pleiotropic Biosynthesis of Natural Products. Angewandte Chemie International Edition 54, 7592-7596. http://dx.doi.org/10.1002/anie.201502452

Muria-Gonzalez MJ, Chooi Y-H, Breen S and Solomon PS (2015) The past, present and future of secondary metabolite research in the Dothideomycetes. Molecular Plant Pathology 16, 92-107. http://dx.doi.org/10.1111/mpp.12162

Nasiri J, Motamedi E and Reza Naghavi M (2015) Comparative study of adsorptive role of carbonaceous materials in removal of UV-active impurities of paclitaxel extracts. Journal of Pharmaceutical Analysis 5, 396-399. //www.sciencedirect.com/science/article/pii/S2095177915000404

Newman DJ, Cragg GM and Kingston DGI (2015) Chapter 5 - Natural Products as Pharmaceuticals and Sources for Lead Structures*. In The Practice of Medicinal Chemistry (Fourth Edition). (Ed.^(Eds  pp. 101-139. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780124172050000055

Nisa H, Kamili AN, Nawchoo IA, Shafi S, Shameem N and Bandh SA (2015) Fungal endophytes as prolific source of phytochemicals and other bioactive natural products: A review. Microbial Pathogenesis 82, 50-59. //www.sciencedirect.com/science/article/pii/S0882401015000601

OConnor SE (2015) Fighting cancer while saving the mayapple. Science 349, 1167-1168. http://science.sciencemag.org

Oliver MA and Gregory PJ (2015) Soil, food security and human health: a review. European Journal of Soil Science 66, 257-276. http://dx.doi.org/10.1111/ejss.12216

Pandey A and Agnihotri V (2015) Antimicrobials from medicinal plants. In Biotechnology of Bioactive Compounds. (Ed.^(Eds  pp. 123-150. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118733103.ch5

Pons DG, Torrens-Mas M, Nadal-Serrano M, Sastre-Serra J, Roca P and Oliver J (2015) The presence of Estrogen Receptor β modulates the response of breast cancer cells to therapeutic agents. The International Journal of Biochemistry & Cell Biology 66, 85-94. //www.sciencedirect.com/science/article/pii/S1357272515001995

Radogna F, Dicato M and Diederich M (2015) Cancer-type-specific crosstalk between autophagy, necroptosis and apoptosis as a pharmacological target. Biochemical Pharmacology 94, 1-11. //www.sciencedirect.com/science/article/pii/S0006295214007321

Rahpeyma S-A, Moieni A and Jalali Javaran M (2015) Paclitaxel production is enhanced in suspension-cultured hazel (Corylus avellana L.) cells by using a combination of sugar, precursor, and elicitor. Engineering in Life Sciences 15, 234-242. http://dx.doi.org/10.1002/elsc.201400115

Ramer R and Hinz B (2015) Chapter Two - New Insights into Antimetastatic and Antiangiogenic Effects of Cannabinoids. In International Review of Cell and Molecular Biology. (Ed.^(Eds Kwang WJ) pp. 43-116. (Academic Press). //www.sciencedirect.com/science/article/pii/S1937644814000082

Reddy DV, Sabitha G and Yadav JS (2015) A cross-metathesis approach to the synthesis of (+)-phomopsolide B. Tetrahedron Letters 56, 4112-4114. //www.sciencedirect.com/science/article/pii/S0040403915008412

Reski R, Parsons J and Decker EL (2015) Moss-made pharmaceuticals: from bench to bedside. Plant Biotechnology Journal 13, 1191-1198. http://dx.doi.org/10.1111/pbi.12401

Roopa G, Madhusudhan MC, Sunil KCR, Lisa N, Calvin R, Poornima R, Zeinab N, Kini KR, Prakash HS and Geetha N (2015) Identification of Taxol-producing endophytic fungi isolated from Salacia oblonga through genomic mining approach. Journal of Genetic Engineering and Biotechnology 13, 119-127. //www.sciencedirect.com/science/article/pii/S1687157X15000359

Saeed MEM, Abdelgadir H, Sugimoto Y, Khalid HE and Efferth T (2015) Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells. Journal of Ethnopharmacology 174, 644-658. //www.sciencedirect.com/science/article/pii/S0378874115300222

Sarkar IN (2015) Chapter 17 - Challenges in Identification of Potential Phytotherapies from Contemporary Biomedical Literature A2 - Mukherjee, Pulok K. In Evidence-Based Validation of Herbal Medicine. (Ed.^(Eds  pp. 363-371. (Elsevier: Boston). //www.sciencedirect.com/science/article/pii/B9780128008744000179

Seifert S, Weidner SM, Panne U and Kneipp J (2015) Taxonomic relationships of pollens from matrix-assisted laser desorption/ionization time-of-flight mass spectrometry data using multivariate statistics. Rapid Communications in Mass Spectrometry 29, 1145-1154. http://dx.doi.org/10.1002/rcm.7207

Sharma H and Garg M (2015) A review of traditional use, phytoconstituents and biological activities of Himalayan yew, Taxus wallichiana. Journal of Integrative Medicine 13, 80-90. //www.sciencedirect.com/science/article/pii/S2095496415601613

Sharma S, Verma A, Teja BV, Shukla P and Mishra PR (2015) Development of stabilized Paclitaxel nanocrystals: In-vitro and in-vivo efficacy studies. European Journal of Pharmaceutical Sciences 69, 51-60. //www.sciencedirect.com/science/article/pii/S0928098714004448

Shaw JJ, Berbasova T, Sasaki T, Jefferson-George K, Spakowicz DJ, Dunican BF, Portero CE, Narvaez-Trujillo A and Strobel SA (2015) Identification of a Fungal 1,8-Cineole Synthase from Hypoxylon sp. with Specificity Determinants in Common with the Plant Synthases. J. Biol. Chem. 290, 8511-8526. http://www.jbc.org/cgi/content/abstract/290/13/8511

Shiota M, Itsumi M, Yokomizo A, Takeuchi A, Imada K, Kashiwagi E, Inokuchi J, Tatsugami K, Uchiumi T and Naito S (2015) MP46-11 TARGETING RIBOSOMAL S6 KINASES/Y-BOX BINDING PROTEIN-1 SIGNALING IMPROVES CELLULAR SENSITIVITY TO TAXANE IN PROSTATE CANCER. The Journal of Urology 193, e547-e548. //www.sciencedirect.com/science/article/pii/S0022534715018856

Sloboda RD (2015) Isolation and Analysis of Microtubules and Associated Proteins. Cold Spring Harb Protoc 2015, pdb.top074526-. http://cshprotocols.cshlp.org/cgi/content/abstract/2015/2/pdb.top074526

Soliman S and Tang Y (2015) Natural and engineered production of taxadiene with taxadiene synthase. Biotechnology and Bioengineering 112, 229-235. http://dx.doi.org/10.1002/bit.25468

Sun Z-H, Chen Y, Guo Y-Q, Qiu J, Zhu C-G, Jin J, Tang G-H, Bu X-Z and Yin S (2015) Isolation and cytotoxicity evaluation of taxanes from the barks of Taxus wallichiana var. mairei. Bioorganic & Medicinal Chemistry Letters 25, 1240-1243. //www.sciencedirect.com/science/article/pii/S0960894X15000761

Szalai R, Ganczer A, Magyari L, Matyas P, Bene J and Melegh B (2015) Interethnic differences of cytochrome P450 gene polymorphisms may influence outcome of taxane therapy in Roma and Hungarian populations. Drug Metabolism and Pharmacokinetics 30, 453-456. //www.sciencedirect.com/science/article/pii/S1347436715000488

Talbot Nicholas J (2015) Plant Immunity: A Little Help from Fungal Friends. Current Biology 25, R1074-R1076. //www.sciencedirect.com/science/article/pii/S0960982215011793

Tham EH, Cheng YK, Tay MH, Alcasabas AP and Shek LP-C (2015) Evaluation and management of hypersensitivity reactions to chemotherapy agents. Postgrad. Med. J. 91, 145-150. http://pmj.bmj.com/cgi/content/abstract/91/1073/145

Thu HP, Nam NH, Quang BT, Son HA, Toan NL and Quang DT (2015) In vitro and in vivo targeting effect of folate decorated paclitaxel loaded PLA–TPGS nanoparticles. Saudi Pharmaceutical Journal 23, 683-688. //www.sciencedirect.com/science/article/pii/S1319016415000407

Trouiller AJ, Hebié S, el Bahhaj F, Napporn TW and Bertrand P (2015) Chemistry for oncotheranostic gold nanoparticles. European Journal of Medicinal Chemistry 99, 92-112. //www.sciencedirect.com/science/article/pii/S0223523415300519

Ueno S, Wen Y and Tsumura Y (2015) Development of EST-SSR markers for Taxus cuspidata from publicly available transcriptome sequences. Biochemical Systematics and Ecology 63, 20-26. //www.sciencedirect.com/science/article/pii/S0305197815002410

Wang L, Li Y-j and Li Z-w (2015) Towards validating new enzymatic routes for synthetic conversion: 7,10-bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetyl baccatin III–ethyl acetate–water (1/1/1). Acta Crystallographica Section C 71, 191-194. http://dx.doi.org/10.1107/S2053229614027399

Wang P, Henning SM, Heber D and Vadgama JV (2015) Sensitization to docetaxel in prostate cancer cells by green tea and quercetin. The Journal of Nutritional Biochemistry 26, 408-415. //www.sciencedirect.com/science/article/pii/S0955286315000078

Wang S, Qiu J, Shi Z, Wang Y and Chen M (2015) Nanoscale drug delivery for taxanes based on the mechanism of multidrug resistance of cancer. Biotechnology Advances 33, 224-241. //www.sciencedirect.com/science/article/pii/S0734975014001608

Wang Z, Ma Z, Wang L, Tang C, Hu Z, Chou G and Li W (2015) Active anti-acetylcholinesterase component of secondary metabolites produced by the endophytic fungi of Huperzia serrata. Electronic Journal of Biotechnology 18, 399-405. //www.sciencedirect.com/science/article/pii/S0717345815000986

Wicki A, Witzigmann D, Balasubramanian V and Huwyler J (2015) Nanomedicine in cancer therapy: Challenges, opportunities, and clinical applications. Journal of Controlled Release 200, 138-157. //www.sciencedirect.com/science/article/pii/S016836591400827X

Wink M (2015) Sekundärstoffe – die Geheimwaffen der Pflanzen. Biologie in unserer Zeit 45, 225-235. http://dx.doi.org/10.1002/biuz.201510569

Xu X-H, Sun B-N, Yan D-F, Wang J and Dong C (2015) A Taxus leafy branch with attached ovules from the Lower Cretaceous of Inner Mongolia, North China. Cretaceous Research 54, 266-282. //www.sciencedirect.com/science/article/pii/S0195667114002444

Yamamoto S, Hayashi S, Furusaki S and Shioya S (2015) 5-Aminolevulinic acid promotes callus growth and paclitaxel production in light-grown Taxus cuspidata suspension cultures. Engineering in Life Sciences 15, 116-121. http://dx.doi.org/10.1002/elsc.201300171

Yan X, Bai M, Ning X, Ouyang H, Zhang S, Yang M and Wu H (2015) Spatiotemporal features of microsporogenesis in the cycad species Macrozamia communis. Am. J. Botany 102, 1061-1072. http://www.amjbot.org/cgi/content/abstract/102/7/1061

Yazan LS, Ong YS, Zaaba NE, Ali RM, Foo JB and Tor YS (2015) Anti-breast cancer properties and toxicity of Dillenia suffruticosa root aqueous extract in BALB/c mice. Asian Pacific Journal of Tropical Biomedicine 5, 1018-1026. //www.sciencedirect.com/science/article/pii/S2221169115002208

Zarrabi A and Vossoughi M (2015) Paclitaxel/β-CD-g-PG inclusion complex: An insight into complexation thermodynamics and guest solubility. Journal of Molecular Liquids 208, 145-150. //www.sciencedirect.com/science/article/pii/S0167732215300234

Zerbe P and Bohlmann J (2015) Plant diterpene synthases: exploring modularity and metabolic diversity for bioengineering. Trends in Biotechnology 33, 419-428. //www.sciencedirect.com/science/article/pii/S0167779915000979

Zhang C, Zhong B, Yang S, Pan L, Yu S, Li Z, Li S, Su B and Meng X (2015) Synthesis and biological evaluation of thiabendazole derivatives as anti-angiogenesis and vascular disrupting agents. Bioorganic & Medicinal Chemistry 23, 3774-3780. //www.sciencedirect.com/science/article/pii/S0968089615002928

Zirngibl M, Fürnrohr BG, Janko C, Munoz LE, Voll RE, Gregory CD, Schett G and Herrmann M (2015) Loading of nuclear autoantigens prototypically recognized by systemic lupus erythematosus sera into late apoptotic vesicles requires intact microtubules and myosin light chain kinase activity. Clinical & Experimental Immunology 179, 39-49. http://dx.doi.org/10.1111/cei.12342

(2014) Chapter 14 - Stem Cells for Discovery of Effective and Safe New Drugs A2 - Mummery, Christine. In Stem Cells (Second Edition). (Ed.^(Eds Stolpe Avd, Roelen BAJ and Clevers H) pp. 363-379. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780124115514000143

(2014) Index A2 - Wexler, Philip. In Encyclopedia of Toxicology (Third Edition). (Ed.^(Eds  pp. 1067-1276. (Academic Press: Oxford). //www.sciencedirect.com/science/article/pii/B9780123864543180017

(2014) PM 8/2 (2) Coniferae. EPPO Bulletin 44, 403-440. http://dx.doi.org/10.1111/epp.12163

Abouzeid AH, Patel NR and Torchilin VP (2014) Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin E micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer. International Journal of Pharmaceutics 464, 178-184. //www.sciencedirect.com/science/article/pii/S0378517314000192

Abraham JE, Guo Q, Dorling L, Tyrer J, Ingle S, Hardy R, Vallier A-L, Hiller L, Burns R, Jones L, Bowden SJ, Dunn JA, Poole CJ, Caldas C, Pharoah PPD and Earl HM (2014) Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel. Clin. Cancer Res. 20, 2466-2475. http://clincancerres.aacrjournals.org/cgi/content/abstract/20/9/2466

Adelin E, Servy C, Martin M-T, Arcile G, Iorga BI, Retailleau P, Bonfill M and Ouazzani J (2014) Bicyclic and tetracyclic diterpenes from a Trichoderma symbiont of Taxus baccata. Phytochemistry 97, 55-61. //www.sciencedirect.com/science/article/pii/S0031942213004135

Adesina SK, Holly A, Kramer-Marek G, Capala J and Akala EO (2014) Polylactide-Based Paclitaxel-Loaded Nanoparticles Fabricated by Dispersion Polymerization: Characterization, Evaluation in Cancer Cell Lines, and Preliminary Biodistribution Studies. Journal of Pharmaceutical Sciences 103, 2546-2555. //www.sciencedirect.com/science/article/pii/S0022354915304779

Ahmed EM, El-Maraghy SA, Teleb ZA and Shaheen AA (2014) Pretreatment with turmeric modulates the inhibitory influence of cisplatin and paclitaxel on CYP2E1 and CYP3A1/2 in isolated rat hepatic microsomes. Chemico-Biological Interactions 220, 25-32. //www.sciencedirect.com/science/article/pii/S0009279714001653

Alvin A, Miller KI and Neilan BA (2014) Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds. Microbiological Research 169, 483-495. //www.sciencedirect.com/science/article/pii/S0944501313002140

Andoh T, Kitamura R, Fushimi H, Komatsu K, Shibahara N and Kuraishi Y (2014) Effects of Goshajinkigan, Hachimijiogan, and Rokumigan on Mechanical Allodynia Induced by Paclitaxel in Mice. Journal of Traditional and Complementary Medicine 4, 293-297. //www.sciencedirect.com/science/article/pii/S2225411016302486

Baer P, Rabe P, Citron CA, de Oliveira Mann CC, Kaufmann N, Groll M and Dickschat JS (2014) Hedycaryol Synthase in Complex with Nerolidol Reveals Terpene Cyclase Mechanism. ChemBioChem 15, 213-216. http://dx.doi.org/10.1002/cbic.201300708

Berkov S, Mutafova B and Christen P (2014) Molecular biodiversity and recent analytical developments: A marriage of convenience. Biotechnology Advances 32, 1102-1110. //www.sciencedirect.com/science/article/pii/S0734975014000524

Bermudez JM, Cid AG, Ramírez-Rigo MV, Quinteros D, Simonazzi A, Sánchez Bruni S and Palma S (2014) Challenges and opportunities in polymer technology applied to veterinary medicine. Journal of Veterinary Pharmacology and Therapeutics 37, 105-124. http://dx.doi.org/10.1111/jvp.12079

Brück T, Kourist R and Loll B (2014) Production of Macrocyclic Sesqui- and Diterpenes in Heterologous Microbial Hosts: A Systems Approach to Harness Nature’s Molecular Diversity. ChemCatChem 6, 1142-1165. http://dx.doi.org/10.1002/cctc.201300733

Búfalo MC, Bordon-Graciani AP, Conti BJ, de Assis Golim M and Sforcin JM (2014) The immunomodulatory effect of propolis on receptors expression, cytokine production and fungicidal activity of human monocytes. Journal of Pharmacy and Pharmacology 66, 1497-1504. http://dx.doi.org/10.1111/jphp.12279

Cai J, Chen S, Zhang W, Hu S, Lu J, Xing J and Dong Y (2014) Paeonol reverses paclitaxel resistance in human breast cancer cells by regulating the expression of transgelin 2. Phytomedicine 21, 984-991. //www.sciencedirect.com/science/article/pii/S0944711314001147

Calastretti A, Gatti G, Quaresmini C and Bevilacqua A (2014) Down-modulation of Bcl-2 sensitizes PTEN-mutated prostate cancer cells to starvation and taxanes. The Prostate 74, 1411-1422. http://dx.doi.org/10.1002/pros.22857

Cerella C, Teiten M-H, Radogna F, Dicato M and Diederich M (2014) From nature to bedside: Pro-survival and cell death mechanisms as therapeutic targets in cancer treatment. Biotechnology Advances 32, 1111-1122. //www.sciencedirect.com/science/article/pii/S0734975014000421

Cheng H-Y and Ko F-H (2014) Studying the enhancement of programmed cell death by combined AG1024 and paclitaxel in a model of chronic myelogenous leukemia. Life Sciences 102, 118-126. //www.sciencedirect.com/science/article/pii/S0024320514003397

Chirio D, Gallarate M, Peira E, Battaglia L, Muntoni E, Riganti C, Biasibetti E, Capucchio MT, Valazza A, Panciani P, Lanotte M, Annovazzi L, Caldera V, Mellai M, Filice G, Corona S and Schiffer D (2014) Positive-charged solid lipid nanoparticles as paclitaxel drug delivery system in glioblastoma treatment. European Journal of Pharmaceutics and Biopharmaceutics 88, 746-758. //www.sciencedirect.com/science/article/pii/S0939641114003166

Choudhury H, Gorain B, Karmakar S and Pal TK (2014) Development and Validation of RP-HPLC Method: Scope of Application in the Determination of Oil Solubility of Paclitaxel. J Chromatogr Sci 52, 68-74. http://chromsci.oxfordjournals.org/cgi/content/abstract/52/1/68

Coelho PS, Arnold FH and Lewis JC (2014) 9.15 Synthetic Biology Approaches for Organic Synthesis A2 - Knochel, Paul. In Comprehensive Organic Synthesis II (Second Edition). (Ed.^(Eds  pp. 390-420. (Elsevier: Amsterdam). //www.sciencedirect.com/science/article/pii/B9780080977423009319

Cusido RM, Onrubia M, Sabater-Jara AB, Moyano E, Bonfill M, Goossens A, Angeles Pedreńo M and Palazon J (2014) A rational approach to improving the biotechnological production of taxanes in plant cell cultures of Taxus spp. Biotechnology Advances 32, 1157-1167. //www.sciencedirect.com/science/article/pii/S073497501400038X

Dech JP, Mayhew-Hammond S, James AL and Pokharel B (2014) Modeling Canada yew (Taxus canadensis Marsh.) distribution and abundance in the boreal forest of northeastern Ontario, Canada. Ecological Indicators 36, 48-58. //www.sciencedirect.com/science/article/pii/S1470160X13002483

Ding H and Xu F (2014) Chapter 20 - Production of Phytochemicals, Dyes and Pigments as Coproducts in Bioenergy Processes. In Bioenergy Research: Advances and Applications. (Ed.^(Eds  pp. 353-365. (Elsevier: Amsterdam). //www.sciencedirect.com/science/article/pii/B9780444595614000206

Dolanc CR, Safford HD, Thorne JH and Dobrowski SZ (2014) Changing forest structure across the landscape of the Sierra Nevada, CA, USA, since the 1930s. Ecosphere 5, 1-26. http://dx.doi.org/10.1890/ES14-00103.1

Dörken VM and Jagel A (2014) Orientation and withdrawal of pollination drops in Cupressaceae s. l. (Coniferales). Flora - Morphology, Distribution, Functional Ecology of Plants 209, 34-44. //www.sciencedirect.com/science/article/pii/S036725301300128X

Eagle SR and Gad SC (2014) Natural Products A2 - Wexler, Philip. In Encyclopedia of Toxicology (Third Edition). (Ed.^(Eds  pp. 468-469. (Academic Press: Oxford). //www.sciencedirect.com/science/article/pii/B9780123864543009726

Eirich J and Sieber SA (2014) Naturstoffe und ihre zellulären Angriffsziele. Nachrichten aus der Chemie 62, 743-747. http://dx.doi.org/10.1002/nadc.201490249

Feng L, Jiang H, Zhang Y and Zhang S (2014) Sexual differences in defensive and protective mechanisms of Populus cathayana exposed to high UV-B radiation and low soil nutrient status. Physiologia Plantarum 151, 434-445. http://dx.doi.org/10.1111/ppl.12126

Fernández-Peralbo MA, Priego-Capote F, Luque de Castro MD, Casado-Adam A, Arjona-Sánchez A and Muńoz-Casares FC (2014) LC–MS/MS quantitative analysis of paclitaxel and its major metabolites in serum, plasma and tissue from women with ovarian cancer after intraperitoneal chemotherapy. Journal of Pharmaceutical and Biomedical Analysis 91, 131-137. //www.sciencedirect.com/science/article/pii/S0731708513006134

Fissell Iv WH and Earl M (2014) Chapter 15 - Pharmacokinetics of Anti-cancer Chemotherapy in Renal Insufficiency and Dialysis A2 - Finkel, Kevin W. In Renal Disease in Cancer Patients. (Ed.^(Eds Howard SC) pp. 251-269. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780124159488000155

Ghosh AK and Gemma S (2014) From Traditional Medicine to Modern Drugs: Historical Perspective of Structure-Based Drug Design. In Structure-Based Design of Drugs and Other Bioactive Molecules. (Ed.^(Eds  pp. 1-18. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527665211.ch1

Giuffrida MC, Dosio F, Castelli F and Sarpietro MG (2014) Lipophilic prodrug of paclitaxel: Interaction with a dimyristoylphosphatidylcholine monolayer. International Journal of Pharmaceutics 475, 624-631. //www.sciencedirect.com/science/article/pii/S0378517314006760

Goey AKL, Beijnen JH and Schellens JHM (2014) Herb–Drug Interactions in Oncology. Clinical Pharmacology & Therapeutics 95, 354-355. http://dx.doi.org/10.1038/clpt.2014.18

Gond SK, Kharwar RN and White JF (2014) Will fungi be the new source of the blockbuster drug taxol? Fungal biology reviews., 28. http://dx.doi.org/10.1016/j.fbr.2014.10.001

Gond SK, Kharwar RN and White Jr JF (2014) Will fungi be the new source of the blockbuster drug taxol? Fungal Biology Reviews 28, 77-84. //www.sciencedirect.com/science/article/pii/S1749461314000281

Gupta PN, Jain S, Nehate C, Alam N, Khare V, Dubey RD, Saneja A, Kour S and Singh SK (2014) Development and evaluation of paclitaxel loaded PLGA:poloxamer blend nanoparticles for cancer chemotherapy. International Journal of Biological Macromolecules 69, 393-399. //www.sciencedirect.com/science/article/pii/S0141813014003742

Hagmann RK, Franklin JF and Johnson KN (2014) Historical conditions in mixed-conifer forests on the eastern slopes of the northern Oregon Cascade Range, USA. Forest Ecology and Management 330, 158-170. //www.sciencedirect.com/science/article/pii/S0378112714004253

Hammerschmidt L, Debbab A, Ngoc TD, Wray V, Hemphil CP, Lin W, Broetz-Oesterhelt H, Kassack MU, Proksch P and Aly AH (2014) Polyketides from the mangrove-derived endophytic fungus Acremonium strictum. Tetrahedron Letters 55, 3463-3468. //www.sciencedirect.com/science/article/pii/S0040403914006881

Han F, Kang L-Z, Zeng X-L, Ye Z-W, Guo L-Q and Lin J-F (2014) Bioproduction of baccatin III, an advanced precursor of paclitaxol, with transgenic Flammulina velutipes expressing the 10-deacetylbaccatin III-10-O-acetyl transferase gene. Journal of the Science of Food and Agriculture 94, 2376-2383. http://dx.doi.org/10.1002/jsfa.6562

Hendrikx JJMA, Rosing H, Schinkel AH, Schellens JHM and Beijnen JH (2014) Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS. Biomedical Chromatography 28, 302-310. http://dx.doi.org/10.1002/bmc.3021

Hoke A and Ray M (2014) Rodent Models of Chemotherapy-Induced Peripheral Neuropathy. ILAR J 54, 273-281. http://ilarjournal.oxfordjournals.org/cgi/content/abstract/54/3/273

Howat S, Park B, Oh IS, Jin Y-W, Lee E-K and Loake GJ (2014) Paclitaxel: biosynthesis, production and future prospects. New Biotechnology 31, 242-245. //www.sciencedirect.com/science/article/pii/S1871678414000235

Huang X, Liang Z, Chen H, Zhao Z and Li P (2014) Identification of Chinese herbal medicines by fluorescence microscopy: fluorescent characteristics of medicinal bark. Journal of Microscopy 256, 6-22. http://dx.doi.org/10.1111/jmi.12153

Jain A, Gulbake A, Jain A, Shilpi S, Hurkat P, Kashaw S and Jain SK (2014) Development and Validation of the HPLC Method for Simultaneous Estimation of Paclitaxel and Topotecan. J Chromatogr Sci 52, 697-703. http://chromsci.oxfordjournals.org/cgi/content/abstract/52/7/697

Jeandet P, Clément C and Courot E (2014) Resveratrol production at large scale using plant cell suspensions. Engineering in Life Sciences 14, 622-632. http://dx.doi.org/10.1002/elsc.201400022

Jones RE and Lopez KH (2014) Chapter 2 - The Female Reproductive System. In Human Reproductive Biology (Fourth Edition). (Ed.^(Eds  pp. 23-50. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780123821843000027

Joseph B, Vishwanath L and Venugopal BK (2014) Radiosensitization in head and neck cancer: do we have an alternative to platins? Role of taxanes. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 117, 324-328. //www.sciencedirect.com/science/article/pii/S2212440313006007

Jules ES, Carroll AL, Garcia AM, Steenbock CM and Kauffman MJ (2014) Host heterogeneity influences the impact of a non-native disease invasion on populations of a foundation tree species. Ecosphere 5, 1-17. http://dx.doi.org/10.1890/ES14-00043.1

Juyal D, Thawani V, Thaledi S and Joshi M (2014) Ethnomedical Properties of Taxus Wallichiana Zucc. (Himalayan Yew). Journal of Traditional and Complementary Medicine 4, 159-161. //www.sciencedirect.com/science/article/pii/S2225411016302280

Kachooei E, Moosavi-Movahedi AA, Khodagholi F, Mozaffarian F, Sadeghi P, Hadi-Alijanvand H, Ghasemi A, Saboury AA, Farhadi M and Sheibani N (2014) Inhibition study on insulin fibrillation and cytotoxicity by paclitaxel. J. Biochem. 155, 361-373. http://jb.oxfordjournals.org/cgi/content/abstract/155/6/361

Kandel SE, Wienkers LC and Lampe JN (2014) Chapter Twenty-Two - Cytochrome P450 Enzyme Metabolites in Lead Discovery and Development. In Annual Reports in Medicinal Chemistry. (Ed.^(Eds Manoj CD) pp. 347-359. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780128001677000225

Kelly S, Grenyer R and Scotland RW (2014) Phylogenetic trees do not reliably predict feature diversity. Diversity and Distributions 20, 600-612. http://dx.doi.org/10.1111/ddi.12188

Khan M, Taibjee SM, Poole CJ and Gach JE (2014) Bullous reaction at docetaxel infusion site. Clinical and Experimental Dermatology 39, 58-60. http://dx.doi.org/10.1111/ced.12182

Khazir J, Mir BA, Pilcher L and Riley DL (2014) Role of plants in anticancer drug discovery. Phytochemistry Letters 7, 173-181. //www.sciencedirect.com/science/article/pii/S1874390013002061

Ko M-H, Hu M-E, Hsieh Y-L, Lan C-T and Tseng T-J (2014) Peptidergic intraepidermal nerve fibers in the skin contribute to the neuropathic pain in paclitaxel-induced peripheral neuropathy. Neuropeptides 48, 109-117. //www.sciencedirect.com/science/article/pii/S014341791400016X

Koudous I, Both S, Gudi G, Schulz H and Strube J (2014) Process design based on physicochemical properties for the example of obtaining valuable products from plant-based extracts. Comptes Rendus Chimie 17, 218-231. //www.sciencedirect.com/science/article/pii/S1631074813003640

Kusari S, Singh S and Jayabaskaran C (2014) Rethinking production of Taxol® (paclitaxel) using endophyte biotechnology. Trends in Biotechnology 32, 304-311. //www.sciencedirect.com/science/article/pii/S016777991400064X

Lee J, Jo D-G, Park D, Chung HY and Mattson MP (2014) Adaptive Cellular Stress Pathways as Therapeutic Targets of Dietary Phytochemicals: Focus on the Nervous System. Pharmacol. Rev. 66, 815-868. http://pharmrev.aspetjournals.org/cgi/content/abstract/66/3/815

Lee Y-H, Lee Y-R, Park C-S, Im S-A, Song S, Hong JT, Whang BY, Kim K and Lee C-K (2014) Baccatin III, a precursor for the semisynthesis of paclitaxel, inhibits the accumulation and suppressive activity of myeloid-derived suppressor cells in tumor-bearing mice. International Immunopharmacology 21, 487-493. //www.sciencedirect.com/science/article/pii/S1567576914002264

Lesgards J-F, Baldovini N, Vidal N and Pietri S (2014) Anticancer Activities of Essential Oils Constituents and Synergy with Conventional Therapies: A Review. Phytotherapy Research 28, 1423-1446. http://dx.doi.org/10.1002/ptr.5165

Li C, Qiu Y, Li X, Liu N and Yao Z (2014) Biological evaluation of new antitumor taxoids: Alteration of substitution at the C-7 and C-10 of docetaxel. Bioorganic & Medicinal Chemistry Letters 24, 855-859. //www.sciencedirect.com/science/article/pii/S0960894X13014674

Li X-Y, Zhao Y, Sun M-G, Shi J-F, Ju R-J, Zhang C-X, Li X-T, Zhao W-Y, Mu L-M, Zeng F, Lou J-N and Lu W-L (2014) Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma. Biomaterials 35, 5591-5604. //www.sciencedirect.com/science/article/pii/S0142961214003093

Li Y, Fan L, Sun Y, Miao X, Zhang F, Meng J, Han J, Zhang D, Zhang R, Yue Z and Mei Q (2014) Paris saponin VII from trillium tschonoskii reverses multidrug resistance of adriamycin-resistant MCF-7/ADR cells via P-glycoprotein inhibition and apoptosis augmentation. Journal of Ethnopharmacology 154, 728-734. //www.sciencedirect.com/science/article/pii/S0378874114003481

Li Y, Sun Y, Fan L, Zhang F, Meng J, Han J, Guo X, Zhang D, Zhang R, Yue Z and Mei Q (2014) Paris saponin VII inhibits growth of colorectal cancer cells through Ras signaling pathway. Biochemical Pharmacology 88, 150-157. //www.sciencedirect.com/science/article/pii/S0006295214000422

Lu Y, Wang Z-h, Li T, McNally H, Park K and Sturek M (2014) Development and evaluation of transferrin-stabilized paclitaxel nanocrystal formulation. Journal of Controlled Release 176, 76-85. //www.sciencedirect.com/science/article/pii/S0168365913009607

Ludwig-Müller J, Jahn L, Lippert A, Püschel J and Walter A (2014) Improvement of hairy root cultures and plants by changing biosynthetic pathways leading to pharmaceutical metabolites: Strategies and applications. Biotechnology Advances 32, 1168-1179. //www.sciencedirect.com/science/article/pii/S0734975014000433

Lutz JA, Larson AJ, Furniss TJ, Donato DC, Freund JA, Swanson ME, Bible KJ, Chen J and Franklin JF (2014) Spatially nonrandom tree mortality and ingrowth maintain equilibrium pattern in an old-growth Pseudotsuga–Tsuga forest. Ecology 95, 2047-2054. http://dx.doi.org/10.1890/14-0157.1

Lutz JA, Larson AJ, Furniss TJ, Donato DC, Freund JA, Swanson ME, Bible KJ, Chen J and Franklin JF (2014) Spatially nonrandom tree mortality and ingrowth maintain equilibrium pattern in an old?growth Pseudotsuga–Tsuga forest. Ecology. 95, 2047-2054. http://dx.doi.org/10.1890/14-0157.1

Mase N and Hayashi Y (2014) 2.07 The Aldol Reaction: Organocatalysis Approach A2 - Knochel, Paul. In Comprehensive Organic Synthesis II (Second Edition). (Ed.^(Eds  pp. 273-339. (Elsevier: Amsterdam). //www.sciencedirect.com/science/article/pii/B9780080977423002081

Mazzio E, Badisa R, Mack N, Deiab S and Soliman KFA (2014) High Throughput Screening of Natural Products for Anti-mitotic Effects in MDA-MB-231 Human Breast Carcinoma Cells. Phytotherapy Research 28, 856-867. http://dx.doi.org/10.1002/ptr.5065

Mazzio E, Badisa R, Mack N, Deiab S and Soliman KFA (2014) High Throughput Screening of Natural Products for Anti?mitotic Effects in MDA?MB?231 Human Breast Carcinoma Cells. Phytotherapy research. 28, 856-867. http://dx.doi.org/10.1002/ptr.5065

Miao YC, Lang XD, Zhang ZZ and Su JR (2014) Phylogeography and genetic effects of habitat fragmentation on endangered Taxus yunnanensis in southwest China as revealed by microsatellite data. Plant Biology 16, 365-374. http://dx.doi.org/10.1111/plb.12059

Mirata MA (2014) Microbial Cell Factories: Towards an Industrial Production of Isoprenoids. ChemCatChem 6, 955-957. http://dx.doi.org/10.1002/cctc.201300833

Morrison DJ, Cruickshank MG and Lalumičre A (2014) Control of laminated and Armillaria root diseases by stump removal and tree species mixtures: Amount and cause of mortality and impact on yield after 40 years. Forest Ecology and Management 319, 75-98. //www.sciencedirect.com/science/article/pii/S0378112714000929

Mukhtar E, Adhami VM and Mukhtar H (2014) Targeting Microtubules by Natural Agents for Cancer Therapy. Mol. Cancer Ther. 13, 275-284. http://mct.aacrjournals.org/cgi/content/abstract/13/2/275

Nepali K, Sharma S, Sharma M, Bedi PMS and Dhar KL (2014) Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids. European Journal of Medicinal Chemistry 77, 422-487. //www.sciencedirect.com/science/article/pii/S0223523414002220

Nicolaou KC (2014) Organic synthesis: the art and science of replicating the molecules of living nature and creating others like them in the laboratory. Proc R Soc A 470, 20130690-. http://rspa.royalsocietypublishing.org/cgi/content/abstract/470/2163/20130690

Nicolaou KC and Hale CRH (2014) The endeavor of total synthesis and its impact on chemistry, biology and medicine. Natl Sci Rev 1, 233-252. http://nsr.oxfordjournals.org/cgi/content/abstract/1/2/233

Nielsen MT, Ranberg JA, Christensen U, Christensen HB, Harrison SJ, Olsen CE, Hamberger B, Moller BL and Norholm MHH (2014) Microbial Synthesis of the Forskolin Precursor Manoyl Oxide in an Enantiomerically Pure Form. Appl. Envir. Microbiol. 80, 7258-7265. http://aem.asm.org/cgi/content/abstract/80/23/7258

Nohynek L, Bailey M, Tähtiharju J, Seppänen-Laakso T, Rischer H, Oksman-Caldentey K-M and Puupponen-Pimiä R (2014) Cloudberry (Rubus chamaemorus) cell culture with bioactive substances: Establishment and mass propagation for industrial use. Engineering in Life Sciences 14, 667-675. http://dx.doi.org/10.1002/elsc.201400069

Ogle K, Pathikonda S, Sartor K, Lichstein JW, Osnas JLD and Pacala SW (2014) A model-based meta-analysis for estimating species-specific wood density and identifying potential sources of variation. Journal of Ecology 102, 194-208. http://dx.doi.org/10.1111/1365-2745.12178

Ojima I, Kamath A and Seitz JD (2014) Taxol, Taxoids, and Related Taxanes. In Natural Products in Medicinal Chemistry. (Ed.^(Eds  pp. 127-180. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527676545.ch04

Oßwald W, Fleischmann F, Rigling D, Coelho AC, Cravador A, Diez J, Dalio RJ, Horta Jung M, Pfanz H, Robin C, Sipos G, Solla A, Cech T, Chambery A, Diamandis S, Hansen E, Jung T, Orlikowski LB, Parke J, Prospero S and Werres S (2014) Strategies of attack and defence in woody plant–Phytophthora interactions. Forest Pathology 44, 169-190. http://dx.doi.org/10.1111/efp.12096

Ouahab A, Cheraga N, Onoja V, Shen Y and Tu J (2014) Novel pH-sensitive charge-reversal cell penetrating peptide conjugated PEG-PLA micelles for docetaxel delivery: In vitro study. International Journal of Pharmaceutics 466, 233-245. //www.sciencedirect.com/science/article/pii/S0378517314001525

Pawar VK, Panchal SB, Singh Y, Meher JG, Sharma K, Singh P, Bora HK, Singh A, Datta D and Chourasia MK (2014) Immunotherapeutic vitamin E nanoemulsion synergies the antiproliferative activity of paclitaxel in breast cancer cells via modulating Th1 and Th2 immune response. Journal of Controlled Release 196, 295-306. //www.sciencedirect.com/science/article/pii/S0168365914006944

Pensel PE, Albani C, Gamboa GU, Benoit JP and Elissondo MC (2014) In vitro effect of 5-fluorouracil and paclitaxel on Echinococcus granulosus larvae and cells. Acta Tropica 140, 1-9. //www.sciencedirect.com/science/article/pii/S0001706X14002484

Pérez E, Fernández A, Olmo R, Teijón JM and Blanco MD (2014) pH and glutathion-responsive hydrogel for localized delivery of paclitaxel. Colloids and Surfaces B: Biointerfaces 116, 247-256. //www.sciencedirect.com/science/article/pii/S0927776514000058

Pérez E, Martínez A, Teijón C, Teijón JM and Blanco MD (2014) Bioresponsive nanohydrogels based on HEAA and NIPA for poorly soluble drugs delivery. International Journal of Pharmaceutics 470, 107-119. //www.sciencedirect.com/science/article/pii/S037851731400310X

Picard M, Matulonis UA and Castells M (2014) Chemotherapy Hypersensitivity Reactions in Ovarian Cancer. J Natl Compr Canc Netw 12, 389-402. http://www.jnccn.org/cgi/content/abstract/12/3/389

Poudel RC, Möller M, Liu J, Gao L-M, Baral SR and Li D-Z (2014) Low genetic diversity and high inbreeding of the endangered yews in Central Himalaya: implications for conservation of their highly fragmented populations. Diversity and Distributions 20, 1270-1284. http://dx.doi.org/10.1111/ddi.12237

Rai M, Agarkar G and Rathod D (2014) Multiple Applications of Endophytic Colletotrichum Species Occurring in Medicinal Plants. In Novel Plant Bioresources. (Ed.^(Eds  pp. 227-236. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118460566.ch18

Rajendran P, Rengarajan T, Nandakumar N, Palaniswami R, Nishigaki Y and Nishigaki I (2014) Kaempferol, a potential cytostatic and cure for inflammatory disorders. European Journal of Medicinal Chemistry 86, 103-112. //www.sciencedirect.com/science/article/pii/S0223523414007387

Ramkumar K, Vijayakumar R, Vanitha P, Suganya N, Manjula C, Rajaguru P, Sivasubramanian S and Gunasekaran P (2014) Protective effect of gallic acid on alloxan-induced oxidative stress and osmotic fragility in rats. Human and Experimental Toxicology 33, 638-649. http://het.sagepub.com/cgi/content/abstract/33/6/638

Raut JS and Karuppayil SM (2014) A status review on the medicinal properties of essential oils. Industrial Crops and Products 62, 250-264. //www.sciencedirect.com/science/article/pii/S0926669014005196

Roy A, Bhattacharyya M, Ernsting MJ, May JP and Li S-D (2014) Recent progress in the development of polysaccharide conjugates of docetaxel and paclitaxel. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 6, 349-368. http://dx.doi.org/10.1002/wnan.1264

Roy PP, Ray SD and Ray S (2014) Combined experimental and in silico approaches for exploring antiperoxidative potential of structurally diverse classes of antioxidants on docetaxel-induced lipid peroxidation using 4-HNE as the model marker. Bioorganic Chemistry 56, 1-7. //www.sciencedirect.com/science/article/pii/S0045206814000339

Saadat E, Amini M, Khoshayand MR, Dinarvand R and Dorkoosh FA (2014) Synthesis and optimization of a novel polymeric micelle based on hyaluronic acid and phospholipids for delivery of paclitaxel, in vitro and in-vivo evaluation. International Journal of Pharmaceutics 475, 163-173. //www.sciencedirect.com/science/article/pii/S0378517314005961

Sandhu H and Maddock H (2014) Molecular basis of cancer-therapy-induced cardiotoxicity: introducing microRNA biomarkers for early assessment of subclinical myocardial injury. Clin. Sci. 126, 377-400. http://www.clinsci.org/cgi/content/abstract/126/6/377

Santiago C, Sun L, Munro MHG and Santhanam J (2014) Polyketide and benzopyran compounds of an endophytic fungus isolated from C innamomum mollissimum: biological activity and structure. Asian Pacific Journal of Tropical Biomedicine 4, 627-632. //www.sciencedirect.com/science/article/pii/S2221169115300782

Schnekenburger M, Dicato M and Diederich M (2014) Epigenetic modulators from “The Big Blue”: A treasure to fight against cancer. Cancer Letters 351, 182-197. //www.sciencedirect.com/science/article/pii/S0304383514003097

Schweim JK and Schweim HG (2014) Status quo and future developments of combinations of medicinal products. Synergy 1, 70-75. //www.sciencedirect.com/science/article/pii/S221371301400008X

Shimane M, Ueno Y, Morisaki K, Oogami S, Natsume M, Hayashi K-i, Nozaki H and Kawaide H (2014) Molecular evolution of the substrate specificity of ent-kaurene synthases to adapt to gibberellin biosynthesis in land plants. Biochem. J. 462, 539-546. http://www.biochemj.org/cgi/content/abstract/462/3/539

Shiota M, Itsumi M, Yokomizo A, Takeuchi A, Imada K, Kashiwagi E, Inokuchi J, Tatsugami K, Uchiumi T and Naito S (2014) Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer. The Prostate 74, 829-838. http://dx.doi.org/10.1002/pros.22799

Shu Q, Shen M, Wang B, Cui Q, Zhou X and Zhu L (2014) Aqueous extract of Taxus Chinensis (Pilger) Rehd inhibits lung carcinoma A549 cells through the epidermal growth factor receptor/mitogen-activated protein kinase pathway in vitro and in vivo. Journal of Traditional Chinese Medicine 34, 293-301. //www.sciencedirect.com/science/article/pii/S0254627214600935

Sirikantaramas S, Yamazaki M and Saito K (2014) How Plants Avoid the Toxicity of Self-Produced Defense Bioactive Compounds. In Natural Products. (Ed.^(Eds  pp. 67-82. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118794623.ch4

Smirnova NF, Gayral S, Pedros C, Loirand G, Vaillant N, Malet N, Kassem S, Calise D, Goudouneche D, Wymann MP, Hirsch E, Gadeau A-P, Martinez LO, Saoudi A and Laffargue M (2014) Targeting PI3K{gamma} activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response. J. Exp. Med. 211, 1779-1792. http://jem.rupress.org/cgi/content/abstract/211/9/1779

Srivastava S, Tripathi A and Pandey R (2014) Entophytic Microbes and Biocontrol of Plant Diseases. In Biological Controls for Preventing Food Deterioration. (Ed.^(Eds  pp. 117-137. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118533024.ch6

Stierle U, Hartmann F and Wiegand U (2014) 12 - Interventionelle Therapieverfahren. In Klinikleitfaden Kardiologie (5. Auflage). (Ed.^(Eds  pp. 631-685. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B9783437222825000121

Sudha PN and Rose MH (2014) Chapter Nine - Beneficial Effects of Hyaluronic Acid. In Advances in Food and Nutrition Research. (Ed.^(Eds Se-Kwon K) pp. 137-176. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780128002698000099

Swanson ME, Studevant NM, Campbell JL and Donato DC (2014) Biological associates of early-seral pre-forest in the Pacific Northwest. Forest Ecology and Management 324, 160-171. //www.sciencedirect.com/science/article/pii/S037811271400200X

Tang Y, Chen R, Huang Y, Li G, Huang Y, Chen J, Duan L, Zhu B-T, Thrasher JB, Zhang X and Li B (2014) Natural Compound Alternol Induces Oxidative Stress-Dependent Apoptotic Cell Death Preferentially in Prostate Cancer Cells. Mol. Cancer Ther. 13, 1526-1536. http://mct.aacrjournals.org/cgi/content/abstract/13/6/1526

Taylor P, Colman L and Bajoon J (2014) The search for plants with anticancer activity: Pitfalls at the early stages. Journal of Ethnopharmacology 158, Part A, 246-254. //www.sciencedirect.com/science/article/pii/S0378874114007442

Ullah MF, Bhat SH, Husain E, Abu-Duhier F, Hadi SM, Sarkar FH and Ahmad A (2014) Cancer chemopreventive pharmacology of phytochemicals derived from plants of dietary and non-dietary origin: implication for alternative and complementary approaches. Phytochemistry reviews. 13, 811-833. http://dx.doi.org/10.1007/s11101-014-9341-9

Viúdez A, Ramírez N, Hernández-García I, Carvalho FL, Vera R and Hidalgo M (2014) Nab-paclitaxel: A flattering facelift. Critical Reviews in Oncology/Hematology 92, 166-180. //www.sciencedirect.com/science/article/pii/S1040842814001103

Wang X, Chen Y, Dahmani FZ, Yin L, Zhou J and Yao J (2014) Amphiphilic carboxymethyl chitosan-quercetin conjugate with P-gp inhibitory properties for oral delivery of paclitaxel. Biomaterials 35, 7654-7665. //www.sciencedirect.com/science/article/pii/S0142961214006103

Wang Z, Lin S, Wang D and Huang L (2014) Anti-epidermal growth factor receptor tyrosine kinase activities of traditional Chinese medicine for cancer treatment. European Journal of Integrative Medicine 6, 565-570. //www.sciencedirect.com/science/article/pii/S1876382014000857

Waye A, Annal M, Tang A, Picard G, Harnois F, Guerrero-Analco JA, Saleem A, Hewitt LM, Milestone CB, MacLatchy DL, Trudeau VL and Arnason JT (2014) Canadian boreal pulp and paper feedstocks contain neuroactive substances that interact in vitro with GABA and dopaminergic systems in the brain. Science of The Total Environment 468–469, 315-325. //www.sciencedirect.com/science/article/pii/S0048969713009546

Weaver BA (2014) How Taxol/paclitaxel kills cancer cells. Mol. Biol. Cell 25, 2677-2681. http://www.molbiolcell.org/cgi/content/abstract/25/18/2677

Wilson SA and Roberts SC (2014) Metabolic engineering approaches for production of biochemicals in food and medicinal plants. Current Opinion in Biotechnology 26, 174-182. //www.sciencedirect.com/science/article/pii/S0958166914000172

Xu Q (2014) Paclitaxel. In Handbook of Metabolic Pathways of Xenobiotics. (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118541203.xen444

Xu X, Liu L, Zhang F, Wang W, Li J, Guo L, Che Y and Liu G (2014) Identification of the First Diphenyl Ether Gene Cluster for Pestheic Acid Biosynthesis in Plant Endophyte Pestalotiopsis fici. ChemBioChem 15, 284-292. http://dx.doi.org/10.1002/cbic.201300626

Yadav VG and Stephanopoulos G (2014) Metabolic Engineering: The Ultimate Paradigm for Continuous Pharmaceutical Manufacturing. ChemSusChem 7, 1847-1853. http://dx.doi.org/10.1002/cssc.201301219

Yan H, Wang X, Wang Y, Wang P and Xiao Y (2014) Antiproliferation and anti-migration induced by gypenosides in human colon cancer SW620 and esophageal cancer Eca-109 cells. Human and Experimental Toxicology 33, 522-533. http://het.sagepub.com/cgi/content/abstract/33/5/522

Yang M-Y, Wang C-J, Chen N-F, Ho W-H, Lu F-J and Tseng T-H (2014) Luteolin enhances paclitaxel-induced apoptosis in human breast cancer MDA-MB-231 cells by blocking STAT3. Chemico-Biological Interactions 213, 60-68. //www.sciencedirect.com/science/article/pii/S0009279714000477

You L-F, Guo L-Q, Lin J-F, Ren T and Wang J-R (2014) Overproduction of geranylgeraniol in Coprinopsis cinerea by the expression of geranylgeranyl diphosphate synthase gene. Journal of Basic Microbiology 54, 1387-1394. http://dx.doi.org/10.1002/jobm.201400152

Zhang S, Jiang H, Zhao H, Korpelainen H and Li C (2014) Sexually different physiological responses of Populus cathayana to nitrogen and phosphorus deficiencies. Tree Physiol 34, 343-354. http://treephys.oxfordjournals.org/cgi/content/abstract/34/4/343

(2013) Kapitel 36 - Wichtige Gifte und Vergiftungen. In Allgemeine und spezielle Pharmakologie und Toxikologie (11., Überarbeitete Auflage). (Ed.^(Eds  pp. 967-1099. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B9783437425233000361

(2013) 6 - Komplementäre Verfahren in der Onkologie II A2 - Dobos, Gustav J. In Integrative Onkologie. (Ed.^(Eds  pp. 61-74. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B9783437316289000067

(2013) Index A2 - Grebner, Donald L. In Introduction to Forestry and Natural Resources. (Ed.^(Eds Bettinger P and Siry JP) pp. 479-496. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780123869012180017

(2013) 8 - Herbal approaches to pathological states A2 - Bone, Kerry. In Principles and Practice of Phytotherapy (Second Edition). (Ed.^(Eds Mills S) pp. 140-182. (Churchill Livingstone: Saint Louis). //www.sciencedirect.com/science/article/pii/B9780443069925000086

(2013) Reviews. Chemistry & Industry 77, 46-49. http://dx.doi.org/10.1002/cind.7701_15.x

Aktories K and Unger C (2013) Kapitel 35 - Mittel zur Behandlung von Tumoren - Tumorchemotherapie. In Allgemeine und spezielle Pharmakologie und Toxikologie (11., Überarbeitete Auflage). (Ed.^(Eds  pp. 883-965. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B978343742523300035X

Alan Cox P (2013) Pharmacology, Biodiversity and A2 - Levin, Simon A. In Encyclopedia of Biodiversity (Second Edition). (Ed.^(Eds  pp. 703-715. (Academic Press: Waltham). //www.sciencedirect.com/science/article/pii/B9780123847195001064

Ali I, Haque A, Wani WA, Saleem K and Al Zaabi M (2013) Analyses of anticancer drugs by capillary electrophoresis: a review. Biomedical Chromatography 27, 1296-1311. http://dx.doi.org/10.1002/bmc.2953

Ambhaikar NB (2013) Cancer Drugs. In Drug Discovery. (Ed.^(Eds  pp. 287-336. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118354483.ch8

Asai T, Otsuki S, Taniguchi T, Monde K, Yamashita K, Sakurai H, Ozeki T and Oshima Y (2013) Structures and absolute configurations of short-branched fatty acid dimers from an endophytic fungus of Aloe arborescens. Tetrahedron Letters 54, 3402-3405. //www.sciencedirect.com/science/article/pii/S0040403913006588

Bonini SA, Ferrari-Toninelli G, Montinaro M and Memo M (2013) Notch signalling in adult neurons: a potential target for microtubule stabilization. Therapeutic Advances in Neurological Disorders 6, 375-385. http://tan.sagepub.com/cgi/content/abstract/6/6/375

Bontempo P, Rigano D, Doto A, Formisano C, Conte M, Nebbioso A, Carafa V, Caserta G, Sica V, Molinari AM and Altucci L (2013) Genista sessilifolia DC. extracts induce apoptosis across a range of cancer cell lines. Cell Proliferation 46, 183-192. http://dx.doi.org/10.1111/cpr.12022

Bournine L, Bensalem S, Peixoto P, Gonzalez A, Maiza-Benabdesselam F, Bedjou F, Wauters J-N, Tits M, Frédérich M, Castronovo V and Bellahcčne A (2013) Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells. Phytomedicine 20, 1211-1218. //www.sciencedirect.com/science/article/pii/S0944711313002134

Cameron KS, Howard CB, Izevbigie EB, Hill BJ and Tchounwou PB (2013) Sensitivity and mechanisms of taxol-resistant prostate adenocarcinoma cells to Vernonia amygdalina extract. Experimental and Toxicologic Pathology 65, 759-765. //www.sciencedirect.com/science/article/pii/S094029931200108X

Caron J, Maksimenko A, Wack S, Lepeltier E, Bourgaux C, Morvan E, Leblanc K, Couvreur P and Desmaële D (2013) Improving the Antitumor Activity of Squalenoyl-Paclitaxel Conjugate Nanoassemblies by Manipulating the Linker between Paclitaxel and Squalene. Advanced Healthcare Materials 2, 172-185. http://dx.doi.org/10.1002/adhm.201200099

Chang J, Hao X-D, Hao Y-P, Lu H-F, Yu J-M and Sun X (2013) Design, synthesis and cytotoxicity of novel 3′-N-alkoxycarbonyl docetaxel analogs. Bioorganic & Medicinal Chemistry Letters 23, 6834-6837. //www.sciencedirect.com/science/article/pii/S0960894X13011955

Chen Y, Xie X-G, Ren C-G and Dai C-C (2013) Degradation of N-heterocyclic indole by a novel endophytic fungus Phomopsis liquidambari. Bioresource Technology 129, 568-574. //www.sciencedirect.com/science/article/pii/S0960852412017968

Cheng H-L, Zhao R-Y, Chen T-J, Yu W-B, Wang F, Cheng K-D and Zhu P (2013) Cloning and Characterization of the Glycoside Hydrolases That Remove Xylosyl Groups from 7-{beta}-xylosyl-10-deacetyltaxol and Its Analogues. Mol. Cell. Proteomics 12, 2236-2248. http://www.mcponline.org/cgi/content/abstract/12/8/2236

Choudhury H, Gorain B, Karmakar S and Pal TK (2013) Development and Validation of RP-HPLC Method: Scope of Application in the Determination of Oil Solubility of Paclitaxel. J Chromatogr Sci, bms206. http://chromsci.oxfordjournals.org/cgi/content/abstract/bms206v1

Cleary MR, Arhipova N, Morrison DJ, Thomsen IM, Sturrock RN, Vasaitis R, Gaitnieks T and Stenlid J (2013) Stump removal to control root disease in Canada and Scandinavia: A synthesis of results from long-term trials. Forest Ecology and Management 290, 5-14. //www.sciencedirect.com/science/article/pii/S0378112712003179

Cobb RE, Luo Y, Freestone T and Zhao H (2013) Chapter 10 - Drug Discovery and Development via Synthetic Biology. In Synthetic Biology. (Ed.^(Eds  pp. 183-206. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780123944306000108

Cox PA and King S (2013) Bioprospecting A2 - Levin, Simon A. In Encyclopedia of Biodiversity (Second Edition). (Ed.^(Eds  pp. 588-599. (Academic Press: Waltham). //www.sciencedirect.com/science/article/pii/B9780123847195003506

Crismaru CG, Wybenga GG, Szymanski W, Wijma HJ, Wu B, Bartsch S, de Wildeman S, Poelarends GJ, Feringa BL, Dijkstra BW and Janssen DB (2013) Biochemical Properties and Crystal Structure of a {beta}-Phenylalanine Aminotransferase from Variovorax paradoxus. Appl. Envir. Microbiol. 79, 185-195. http://aem.asm.org/cgi/content/abstract/79/1/185

Cuthbertson DJ, Johnson SR, Piljac-Žegarac J, Kappel J, Schäfer S, Wüst M, Ketchum REB, Croteau RB, Marques JV, Davin LB, Lewis NG, Rolf M, Kutchan TM, Soejarto DD and Lange BM (2013) Accurate mass–time tag library for LC/MS-based metabolite profiling of medicinal plants. Phytochemistry 91, 187-197. //www.sciencedirect.com/science/article/pii/S0031942213000733

Doran PM (2013) Chapter 1 - Bioprocess Development: An Interdisciplinary Challenge. In Bioprocess Engineering Principles (Second Edition). (Ed.^(Eds  pp. 3-11. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780122208515000010

El-Seedi HR, Burman R, Mansour A, Turki Z, Boulos L, Gullbo J and Göransson U (2013) The traditional medical uses and cytotoxic activities of sixty-one Egyptian plants: Discovery of an active cardiac glycoside from Urginea maritima. Journal of Ethnopharmacology 145, 746-757. //www.sciencedirect.com/science/article/pii/S037887411200829X

Elvira Sánchez-Fernández R, Lorena Sánchez-Ortiz B, Monserrat Sandoval-Espinosa YK, Ulloa-Benítez Á, Armendáriz-Guillén B, Claudia García-Méndez M and Lydia Macías-Rubalcava M (2013) Hongos endófitos: fuente potencial de metabolitos secundarios bioactivos con utilidad en agricultura y medicina. TIP 16, 132-146. //www.sciencedirect.com/science/article/pii/S1405888X13720849

Fesko K and Gruber-Khadjawi M (2013) Biocatalytic Methods for CC Bond Formation. ChemCatChem 5, 1248-1272. http://dx.doi.org/10.1002/cctc.201200709

França HS, Rocha L, Fernande CP, Ruiz ALTG and de Carvalho JE (2013) Antiproliferative activity of the hexanic extract and phloroglucinols from Hypericum brasiliense. Revista Brasileira de Farmacognosia 23, 844-847. //www.sciencedirect.com/science/article/pii/S0102695X13701133

Gao F, Wang D and Huang X (2013) Synthesis, isolation, stereostructure and cytotoxicity of paclitaxel analogs from cephalomannine. Fitoterapia 90, 79-84. //www.sciencedirect.com/science/article/pii/S0367326X13001822

Gao L, Liu G, Kang J, Niu M, Wang Z, Wang H, Ma J and Wang X (2013) Paclitaxel nanosuspensions coated with P-gp inhibitory surfactants: I. Acute toxicity and pharmacokinetics studies. Colloids and Surfaces B: Biointerfaces 111, 277-281. //www.sciencedirect.com/science/article/pii/S0927776513003706

Gerwick WH (2013) Plant Sources of Drugs and Chemicals A2 - Levin, Simon A. In Encyclopedia of Biodiversity (Second Edition). (Ed.^(Eds  pp. 129-139. (Academic Press: Waltham). //www.sciencedirect.com/science/article/pii/B9780123847195001118

Gonzalez-Coloma A, Reina M, Diaz CE, Fraga BM and Santana-Meridas O (2013) Natural Product-Based Biopesticides for Insect Control. In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780124095472027700

Gonzalez-Vallinas M, Gonzalez-Castejon M, Rodriguez-Casado A and Ramirez de Molina A (2013) Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives. Nutrition Reviews 71, 585-599. http://nutritionreviews.oxfordjournals.org/cgi/content/abstract/71/9/585

González-Vallinas M, González-Castejón M, Rodríguez-Casado A and Ramírez de Molina A (2013) Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives. Nutrition Reviews 71, 585-599. http://dx.doi.org/10.1111/nure.12051

Grebner DL, Bettinger P and Siry JP (2013) Chapter 1 - A Brief History of Forestry and Natural Resource Management. In Introduction to Forestry and Natural Resources. (Ed.^(Eds  pp. 1-20. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780123869012000014

Grebner DL, Bettinger P and Siry JP (2013) Chapter 9 - Tree Anatomy and Physiology. In Introduction to Forestry and Natural Resources. (Ed.^(Eds  pp. 221-241. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780123869012000099

Grebner DL, Bettinger P and Siry JP (2013) Chapter 4 - Forest Products. In Introduction to Forestry and Natural Resources. (Ed.^(Eds  pp. 97-124. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B978012386901200004X

Grebner DL, Bettinger P and Siry JP (2013) Chapter 2 - Forest Regions of the World. In Introduction to Forestry and Natural Resources. (Ed.^(Eds  pp. 21-76. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780123869012000026

Green S, Brasier CM, Schlenzig A, McCracken A, MacAskill GA, Wilson M and Webber JF (2013) The destructive invasive pathogen Phytophthora lateralis found on Chamaecyparis lawsoniana across the UK. Forest Pathology 43, 19-28. http://dx.doi.org/10.1111/j.1439-0329.2012.00788.x

Gruwez R, Leroux O, De Frenne P, Tack W, Viane R and Verheyen K (2013) Critical phases in the seed development of common juniper (Juniperus communis). Plant Biology 15, 210-219. http://dx.doi.org/10.1111/j.1438-8677.2012.00628.x

Günnewich N, Higashi Y, Feng X, Choi K-B, Schmidt J and Kutchan TM (2013) A diterpene synthase from the clary sage Salvia sclarea catalyzes the cyclization of geranylgeranyl diphosphate to (8R)-hydroxy-copalyl diphosphate. Phytochemistry 91, 93-99. //www.sciencedirect.com/science/article/pii/S0031942212003421

Gupta AP, Pandotra P, Sharma R, Kushwaha M and Gupta S (2013) Chapter 8 - Marine Resource: A Promising Future for Anticancer Drugs. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 229-325. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444596031000084

Hagiwara K, Gailhouste L, Kosaka N and Ochiya T (2013) The Emerging Function of Natural Products as Regulators of miRNAs in Human Diseases. In microRNAs in Toxicology and Medicine. (Ed.^(Eds  pp. 237-248. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118695999.ch15

Hall DE, Zerbe P, Jancsik S, Quesada AL, Dullat H, Madilao LL, Yuen M and Bohlmann J (2013) Evolution of Conifer Diterpene Synthases: Diterpene Resin Acid Biosynthesis in Lodgepole Pine and Jack Pine Involves Monofunctional and Bifunctional Diterpene Synthases. Plant Physiology 161, 600-616. http://www.plantphysiol.org/cgi/content/abstract/161/2/600

Hamann A and Aitken SN (2013) Conservation planning under climate change: accounting for adaptive potential and migration capacity in species distribution models. Diversity and Distributions 19, 268-280. http://dx.doi.org/10.1111/j.1472-4642.2012.00945.x

Heinrich M (2013) Ethnopharmacology and Drug Discovery. In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780124095472027736

Hendrikx JJMA, Lagas JS, Rosing H, Schellens JHM, Beijnen JH and Schinkel AH (2013) P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel. International Journal of Cancer 132, 2439-2447. http://dx.doi.org/10.1002/ijc.27912

Intaraudom C, Boonyuen N, Suvannakad R, Rachtawee P and Pittayakhajonwut P (2013) Penicolinates A–E from endophytic Penicillium sp. BCC16054. Tetrahedron Letters 54, 744-748. //www.sciencedirect.com/science/article/pii/S0040403912019582

Iqbal J, Gunn J and Serruys PW (2013) Coronary stents: historical development, current status and future directions. Br. Med. Bull. 106, 193-211. http://bmb.oxfordjournals.org/cgi/content/abstract/106/1/193

Jain A, Gulbake A, Jain A, Shilpi S, Hurkat P, Kashaw S and Jain SK (2013) Development and Validation of the HPLC Method for Simultaneous Estimation of Paclitaxel and Topotecan. J Chromatogr Sci, bmt101. http://chromsci.oxfordjournals.org/cgi/content/abstract/bmt101v1

Jiang S, Qian D-w, Yang N-y, Tao J-h and Duan J-a (2013) Biodiversity and Antimicrobial Activity of Endophytic Fungi in Angelica sinensis. Chinese Herbal Medicines 5, 264-271. //www.sciencedirect.com/science/article/pii/S1674638413600398

Johnson LM (2013) revisiting the origins of northwest coast packstraps. Museum Anthropology 36, 128-146. http://dx.doi.org/10.1111/muan.12028

Khaled M, Jiang Z-Z and Zhang L-Y (2013) Deoxypodophyllotoxin: A promising therapeutic agent from herbal medicine. Journal of Ethnopharmacology 149, 24-34. //www.sciencedirect.com/science/article/pii/S0378874113004418

Khan KN, Kitajima M, Fujishita A, Nakashima M and Masuzaki H (2013) Toll-like receptor system and endometriosis. Journal of Obstetrics and Gynaecology Research 39, 1281-1292. http://dx.doi.org/10.1111/jog.12117

Kraitzer A, Alperstein D, Kloog Y and Zilberman M (2013) Mechanisms of antiproliferative drug release from bioresorbable porous structures. Journal of Biomedical Materials Research Part A 101A, 1302-1310. http://dx.doi.org/10.1002/jbm.a.34436

Kuppusamy P, Yusoff MM, Maniam GP and Govindan N (2013) A case study – Regulation and functional mechanisms of cancer cells and control its activity using plants and their derivatives. Journal of Pharmacy Research 6, 884-892. //www.sciencedirect.com/science/article/pii/S0974694313003150

Lange BM and Ahkami A (2013) Metabolic engineering of plant monoterpenes, sesquiterpenes and diterpenes—current status and future opportunities. Plant Biotechnology Journal 11, 169-196. http://dx.doi.org/10.1111/pbi.12022

Le Broc-Ryckewaert D, Carpentier R, Lipka E, Daher S, Vaccher C, Betbeder D and Furman C (2013) Development of innovative paclitaxel-loaded small PLGA nanoparticles: Study of their antiproliferative activity and their molecular interactions on prostatic cancer cells. International Journal of Pharmaceutics 454, 712-719. //www.sciencedirect.com/science/article/pii/S0378517313004213

Li J, Cai D, Bi H, Jin J and Huang M (2013) Effects of flavonoids derived from Taxus yunnanensis on p-glycoprotein and cytochrome P450 3A4. Asian Journal of Pharmaceutical Sciences 8, 168-173. //www.sciencedirect.com/science/article/pii/S1818087613000238

Li JJ (2013) History of Drug Discovery. In Drug Discovery. (Ed.^(Eds  pp. 1-42. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118354483.ch1

Li L-q, Li X-l, Fu C-h, Zhao C-f and Yu L-j (2013) Sustainable use of Taxus media cell cultures through minimal growth conservation and manipulation of genome methylation. Process Biochemistry 48, 525-531. //www.sciencedirect.com/science/article/pii/S1359511313000366

Li P, Albrecht BJ, Yan X, Gao M, Weng H-R and Bartlett MG (2013) A rapid analytical method for the quantification of paclitaxel in rat plasma and brain tissue by high-performance liquid chromatography and tandem mass spectrometry. Rapid Communications in Mass Spectrometry 27, 2127-2134. http://dx.doi.org/10.1002/rcm.6671

Li S, Zhang P, Zhang M, Fu C and Yu L (2013) Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biology 15, 19-26. http://dx.doi.org/10.1111/j.1438-8677.2012.00611.x

Lin Y-C, Kuo J-Y, Hsu C-C, Tsai W-C, Li W-C, Yu M-C and Wen H-W (2013) Optimizing manufacture of liposomal berberine with evaluation of its antihepatoma effects in a murine xenograft model. International Journal of Pharmaceutics 441, 381-388. //www.sciencedirect.com/science/article/pii/S0378517312010241

Liu J, Möller M, Provan J, Gao L-M, Poudel RC and Li D-Z (2013) Geological and ecological factors drive cryptic speciation of yews in a biodiversity hotspot. New Phytologist 199, 1093-1108. http://dx.doi.org/10.1111/nph.12336

Liu M, Lin Y-l, Chen X-R, Liao C-C and Poo W-K (2013) In vitro assessment of Macleaya cordata crude extract bioactivity and anticancer properties in normal and cancerous human lung cells. Experimental and Toxicologic Pathology 65, 775-787. //www.sciencedirect.com/science/article/pii/S0940299312001406

Magallon S, Hilu KW and Quandt D (2013) Land plant evolutionary timeline: Gene effects are secondary to fossil constraints in relaxed clock estimation of age and substitution rates. Am. J. Botany 100, 556-573. http://www.amjbot.org/cgi/content/abstract/100/3/556

Mao J, Song B, Shi Y, Wang B, Fan S, Yu X, Tang J and Li L (2013) ShRNA targeting Notch1 sensitizes breast cancer stem cell to paclitaxel. The International Journal of Biochemistry & Cell Biology 45, 1064-1073. //www.sciencedirect.com/science/article/pii/S1357272513000691

Marienhagen J and Bott M (2013) Metabolic engineering of microorganisms for the synthesis of plant natural products. Journal of Biotechnology 163, 166-178. //www.sciencedirect.com/science/article/pii/S0168165612002933

McPherson BA, Erbilgin N, Bonello P and Wood DL (2013) Fungal species assemblages associated with Phytophthora ramorum-infected coast live oaks following bark and ambrosia beetle colonization in northern California. Forest Ecology and Management 291, 30-42. //www.sciencedirect.com/science/article/pii/S037811271200686X

Mercuri AM, Torri P, Casini E and Olmi L (2013) Climate warming and the decline of Taxus airborne pollen in urban pollen rain (Emilia Romagna, northern Italy). Plant Biology 15, 70-82. http://dx.doi.org/10.1111/j.1438-8677.2012.00624.x

Mora-Pale M, Sanchez-Rodriguez SP, Linhardt RJ, Dordick JS and Koffas MAG (2013) Metabolic engineering and in vitro biosynthesis of phytochemicals and non-natural analogues. Plant Science 210, 10-24. //www.sciencedirect.com/science/article/pii/S0168945213001131

Morgan ED (2013) NATURAL PRODUCTS | Supercritical Fluid Chromatography. In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780124095472048319

Morkunas I, Formela M, Floryszak-Wieczorek J, Marczak Ł, Narożna D, Nowak W and Bednarski W (2013) Cross-talk interactions of exogenous nitric oxide and sucrose modulates phenylpropanoid metabolism in yellow lupine embryo axes infected with Fusarium oxysporum. Plant Science 211, 102-121. //www.sciencedirect.com/science/article/pii/S0168945213001635

Nahata A, Saxena A, Suri N, Saxena AK and Dixit VK (2013) Sphaeranthus indicus Induces Apoptosis Through Mitochondrial-Dependent Pathway in HL-60 Cells and Exerts Cytotoxic Potential on Several Human Cancer Cell Lines. Integr Cancer Ther 12, 236-247. http://ict.sagepub.com/cgi/content/abstract/12/3/236

Nakamura K, Shimura N, Otabe Y, Hirai-Morita A, Nakamura Y, Ono N, Ul-Amin MA and Kanaya S (2013) KNApSAcK-3D: A Three-Dimensional Structure Database of Plant Metabolites. Plant Cell Physiol. 54, e4-. http://pcp.oxfordjournals.org/cgi/content/abstract/54/2/e4

Paoli M, Bighelli A, Castola V, Tomi F and Casanova J (2013) Quantification of taxanes in a leaf and twig extract from Taxus baccata L. using 13C NMR spectroscopy. Magnetic Resonance in Chemistry 51, 756-761. http://dx.doi.org/10.1002/mrc.4006

Pessina A, Bonomi A, Parati E, Pallini R and Alessandri G (2013) Primed Mesenchymal Stromal Cells for Cancer Therapy. In Stem Cell Therapeutics for Cancer. (Ed.^(Eds  pp. 187-202. (John Wiley & Sons, Inc). http://dx.doi.org/10.1002/9781118660423.ch14

Peterson FS, Sexton J and Lajtha K (2013) Scaling litter fall in complex terrain: A study from the western Cascades Range, Oregon. Forest Ecology and Management 306, 118-127. //www.sciencedirect.com/science/article/pii/S0378112713003605

Pevida M, Lastra A, Hidalgo A, Baamonde A and Menéndez L (2013) Spinal CCL2 and microglial activation are involved in paclitaxel-evoked cold hyperalgesia. Brain Research Bulletin 95, 21-27. //www.sciencedirect.com/science/article/pii/S0361923013000580

Pham T, Jones J, Metoyer R, Swanson F and Pabst R (2013) Interactive visual analysis promotes exploration of long-term ecological data. Ecosphere 4, 1-22. http://dx.doi.org/10.1890/ES13-00121.1

Pieniążek A, Czepas J, Piasecka-Zelga J, Gwoździński K and Koceva-Chyła A (2013) Oxidative stress induced in rat liver by anticancer drugs doxorubicin, paclitaxel and docetaxel. Advances in Medical Sciences 58, 104-111. //www.sciencedirect.com/science/article/pii/S1896112614601784

Pillai G and Ceballos-Coronel ML (2013) Science and technology of the emerging nanomedicines in cancer therapy: A primer for physicians and pharmacists. SAGE Open Medicine 1, 2050312113513759-. http://smo.sagepub.com/cgi/content/abstract/1/0/2050312113513759

Ramkumar K, Vijayakumar R, Vanitha P, Suganya N, Manjula C, Rajaguru P, Sivasubramanian S and Gunasekaran P (2013) Protective effect of gallic acid on alloxan-induced oxidative stress and osmotic fragility in rats. Human and Experimental Toxicology, 0960327113504792. http://het.sagepub.com/cgi/content/abstract/0960327113504792v1

Ray S, Kundu LM, Goswami S, Roy GC, Chatterjee S, Dutta S, Chaudhuri A and Chakrabarti CS (2013) Metaphase arrest and delay in cell cycle kinetics of root apical meristems and mouse bone marrow cells treated with leaf aqueous extract of Clerodendrum viscosum Vent. Cell Proliferation 46, 109-117. http://dx.doi.org/10.1111/cpr.12011

Roberts AD and Zhang H (2013) Poorly water-soluble drug nanoparticles via solvent evaporation in water-soluble porous polymers. International Journal of Pharmaceutics 447, 241-250. //www.sciencedirect.com/science/article/pii/S037851731300210X

Savietto JP, Furlan CM, Motta LB, Salatino MLF, Carvalho JE, Ruiz ALTG, Salatino A and Santos DYAC (2013) Antiproliferative activity of methanol extracts of four species of Croton on different human cell lines. Revista Brasileira de Farmacognosia 23, 662-667. //www.sciencedirect.com/science/article/pii/S0102695X13700838

Scott PJH (2013) Solid-phase Organic Synthesis of Drugs and Natural Products. In Stereoselective Synthesis of Drugs and Natural Products. (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118596784.ssd003

Seo J-B, Kang S-H, Hur S-H, Park KW, Youn T-J, Park J-S, Yang H-M, Lee H-Y, Kang H-J, Koo B-K, Bae J-H, Kim S-W, Moon K-W, Choi J-W, Lee S-G, Chung W-Y, Kim S-J, Kim D-I, Kim B-O, Hyon M-S, Park K-S, Cha T-J, Yoo C-W, Jeon H-K and Kim H-S (2013) Randomized trial comparing the efficacy between different types of paclitaxel-eluting stents: The comparison of Efficacy between COroflex PLEASe ANd Taxus stent (ECO-PLEASANT) randomized controlled trial. American Heart Journal 165, 733-743. //www.sciencedirect.com/science/article/pii/S0002870313001312

Shah U, Shah R, Acharya S and Acharya N (2013) Novel anticancer agents from plant sources. Chinese Journal of Natural Medicines 11, 16-23. //www.sciencedirect.com/science/article/pii/S1875536413600023

Sharma V and Sarkar IN (2013) Leveraging biodiversity knowledge for potential phyto-therapeutic applications. JAMIA 20, 668-679. http://jamia.bmj.com/cgi/content/abstract/20/4/668

Sharma V and Sarkar IN (2013) Leveraging biodiversity knowledge for potential phyto-therapeutic applications. J Am Med Inform Assoc 20, 668-679. http://jamia.oxfordjournals.org/cgi/content/abstract/20/4/668

Singh S, Ishar MPS, Saxena AK and Kaur A (2013) Cytotoxic effect of Anthocephalus cadamba Miq. leaves on human cancer cell lines. Pharmacognosy Journal 5, 127-129. //www.sciencedirect.com/science/article/pii/S0975357513000291

Takao K-I and Tadano K-I (2013) Chapter 5 - Recent Advances in the Synthetic Studies of Pestalotiopsin A and Related Caryophyllene-Type Sesquiterpenoids. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 161-187. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444626158000059

Taylor P, Arsenak M, Abad MJ, Fernández Á, Milano B, Gonto R, Ruiz M-C, Fraile S, Taylor S, Estrada O and Michelangeli F (2013) Screening of Venezuelan Medicinal Plant Extracts for Cytostatic and Cytotoxic Activity Against Tumor Cell Lines. Phytotherapy Research 27, 530-539. http://dx.doi.org/10.1002/ptr.4752

Tepley AJ, Swanson FJ and Spies TA (2013) Fire-mediated pathways of stand development in Douglas-fir/western hemlock forests of the Pacific Northwest, USA. Ecology 94, 1729-1743. http://dx.doi.org/10.1890/12-1506.1

Thipparaboina R, Khan W and Domb AJ (2013) Eluting combination drugs from stents. International Journal of Pharmaceutics 454, 4-10. //www.sciencedirect.com/science/article/pii/S0378517313006091

Threlfall R (2013) Editorial: Forty Years and Counting. Asian Journal of Organic Chemistry 2, 888-889. http://dx.doi.org/10.1002/ajoc.201300207

Tushingham S, Ardura D, Eerkens JW, Palazoglu M, Shahbaz S and Fiehn O (2013) Hunter-gatherer tobacco smoking: earliest evidence from the Pacific Northwest Coast of North America. Journal of Archaeological Science 40, 1397-1407. //www.sciencedirect.com/science/article/pii/S0305440312004219

Urgenson LS, Halpern CB and Anderson PD (2013) Level and pattern of overstory retention influence rates and forms of tree mortality in mature, coniferous forests of the Pacific Northwest, USA. Forest Ecology and Management 308, 116-127. //www.sciencedirect.com/science/article/pii/S0378112713004544

Varlet V and Augsburger M (2013) Monitoring of aglycons of yew glycosides (3,5-dimethoxyphenol, myrtenol and 1-octen-3-ol) as first indicator of yew presence. Drug Testing and Analysis 5, 474-479. http://dx.doi.org/10.1002/dta.391

Vaughan MM, Wang Q, Webster FX, Kiemle D, Hong YJ, Tantillo DJ, Coates RM, Wray AT, Askew W, ODonnell C, Tokuhisa JG and Tholl D (2013) Formation of the Unusual Semivolatile Diterpene Rhizathalene by the Arabidopsis Class I Terpene Synthase TPS08 in the Root Stele Is Involved in Defense against Belowground Herbivory. PLANT CELL 25, 1108-1125. http://www.plantcell.org/cgi/content/abstract/25/3/1108

Vella-zarb L, Baisch U and Dinnebier RE (2013) Small molecule, big difference: The role of water in the crystallization of paclitaxel. Journal of Pharmaceutical Sciences 102, 674-683. http://dx.doi.org/10.1002/jps.23404

Vieira ILBF, de Souza DCP, da Silva Coelho L, Chen LC and Guillo LA (2013) In vitro mutagenicity and blood compatibility of paclitaxel and curcumin in poly (dl-lactide-co-glicolide) films. Toxicology in Vitro 27, 198-203. //www.sciencedirect.com/science/article/pii/S0887233312002901

Vieira JM and Riley PR (2013) Chemical genetics and its potential in cardiac stem cell therapy. British Journal of Pharmacology 169, 318-327. http://dx.doi.org/10.1111/j.1476-5381.2012.01928.x

Vilos C, Morales FA, Solar PA, Herrera NS, Gonzalez-Nilo FD, Aguayo DA, Mendoza HL, Comer J, Bravo ML, Gonzalez PA, Kato S, Cuello MA, Alonso C, Bravo EJ, Bustamante EI, Owen GI and Velasquez LA (2013) Paclitaxel-PHBV nanoparticles and their toxicity to endometrial and primary ovarian cancer cells. Biomaterials 34, 4098-4108. //www.sciencedirect.com/science/article/pii/S0142961213002032

von Euler H, Rivera P, Nyman H, Häggström J and Borgĺ O (2013) A dose-finding study with a novel water-soluble formulation of paclitaxel for the treatment of malignant high-grade solid tumours in dogs. Veterinary and Comparative Oncology 11, 243-255. http://dx.doi.org/10.1111/j.1476-5829.2011.00314.x

Wacker M (2013) Nanocarriers for intravenous injection—The long hard road to the market. International Journal of Pharmaceutics 457, 50-62. //www.sciencedirect.com/science/article/pii/S0378517313008120

Wessjohann LA, Keim J, Weigel B and Dippe M (2013) Alkylating enzymes. Current Opinion in Chemical Biology 17, 229-235. //www.sciencedirect.com/science/article/pii/S1367593113000318

Wierstra I (2013) Chapter Six - FOXM1 (Forkhead box M1) in Tumorigenesis: Overexpression in Human Cancer, Implication in Tumorigenesis, Oncogenic Functions, Tumor-Suppressive Properties, and Target of Anticancer Therapy. In Advances in Cancer Research. (Ed.^(Eds Kenneth DT and Paul BF) pp. 191-419. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780124071902000162

Wong BS, Yoong SL, Jagusiak A, Panczyk T, Ho HK, Ang WH and Pastorin G (2013) Carbon nanotubes for delivery of small molecule drugs. Advanced Drug Delivery Reviews 65, 1964-2015. //www.sciencedirect.com/science/article/pii/S0169409X13001889

Wriessnegger T and Pichler H (2013) Yeast metabolic engineering – Targeting sterol metabolism and terpenoid formation. Progress in Lipid Research 52, 277-293. //www.sciencedirect.com/science/article/pii/S0163782713000210

Xiao M, Zhang Y, Chen X, Lee E-J, Barber CJS, Chakrabarty R, Desgagné-Penix I, Haslam TM, Kim Y-B, Liu E, MacNevin G, Masada-Atsumi S, Reed DW, Stout JM, Zerbe P, Zhang Y, Bohlmann J, Covello PS, De Luca V, Page JE, Ro D-K, Martin VJJ, Facchini PJ and Sensen CW (2013) Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest. Journal of Biotechnology 166, 122-134. //www.sciencedirect.com/science/article/pii/S0168165613001843

Xie C, Chang J, Hao X-D, Yu J-M, Liu H-R and Sun X (2013) Mitochondrial-targeted prodrug cancer therapy using a rhodamine B labeled fluorinated docetaxel. European Journal of Pharmaceutics and Biopharmaceutics 85, 541-549. //www.sciencedirect.com/science/article/pii/S0939641113002269

Yan C, Yin Y, Zhang D, Yang W and Yu R (2013) Structural characterization and in vitro antitumor activity of a novel polysaccharide from Taxus yunnanensis. Carbohydrate Polymers 96, 389-395. //www.sciencedirect.com/science/article/pii/S0144861713003652

Yang X, Ye Z, Yuan Y, Zheng Z, Shi J, Ying Y and Huang P (2013) Insights into the binding of paclitaxel to human serum albumin: multispectroscopic studies. Luminescence 28, 427-434. http://dx.doi.org/10.1002/bio.2522

Yang X-L, Awakawa T, Wakimoto T and Abe I (2013) Induced production of novel prenyldepside and coumarins in endophytic fungi Pestalotiopsis acaciae. Tetrahedron Letters 54, 5814-5817. //www.sciencedirect.com/science/article/pii/S0040403913014275

Yang X-y, Li Y-x, Li M, Zhang L, Feng L-x and Zhang N (2013) Hyaluronic acid-coated nanostructured lipid carriers for targeting paclitaxel to cancer. Cancer Letters 334, 338-345. //www.sciencedirect.com/science/article/pii/S0304383512003837

Yerlikaya F, Ozgen A, Vural I, Guven O, Karaagaoglu E, Khan MA and Capan Y (2013) Development and Evaluation of Paclitaxel Nanoparticles Using a Quality-by-Design Approach. Journal of Pharmaceutical Sciences 102, 3748-3761. //www.sciencedirect.com/science/article/pii/S0022354915308935

You P, Qiu J, Su E and Wei D (2013) Carica papaya Lipase Catalysed Resolution of β-Amino Esters for the Highly Enantioselective Synthesis of (S)-Dapoxetine. European Journal of Organic Chemistry 2013, 557-565. http://dx.doi.org/10.1002/ejoc.201201055

Yuan J-X, Zeng Y, Zou C and Zhao P-J (2013) Four new β-lactones from the endophytic Streptomyces sp. T1B1. Phytochemistry Letters 6, 625-628. //www.sciencedirect.com/science/article/pii/S1874390013001468

Yue GGL, Chan BCL, Kwok H-F, Wong Y-L, Leung H-W, Ji C-J, Fung K-P, Leung P-C, Tan N-H and Lau CBS (2013) Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica. European Journal of Medicinal Chemistry 59, 243-252. //www.sciencedirect.com/science/article/pii/S0223523412006988

Zabaleta V, Calleja P, Espuelas S, Corrales L, Pío R, Agüeros M and Irache JM (2013) Nanoparticules mucopénétrantes : véhicules pour l’administration orale du paclitaxel. Annales Pharmaceutiques Françaises 71, 109-118. //www.sciencedirect.com/science/article/pii/S0003450913000035

Zacharaki P, Stephanou G and Demopoulos NA (2013) Comparison of the aneugenic properties of nocodazole, paclitaxel and griseofulvin in vitro. Centrosome defects and alterations in protein expression profiles. Journal of Applied Toxicology 33, 869-879. http://dx.doi.org/10.1002/jat.2745

Zerbe P, Hamberger B, Yuen MMS, Chiang A, Sandhu HK, Madilao LL, Nguyen A, Hamberger B, Bach SS and Bohlmann J (2013) Gene Discovery of Modular Diterpene Metabolism in Nonmodel Systems. Plant Physiology 162, 1073-1091. http://www.plantphysiol.org/cgi/content/abstract/162/2/1073

Zhang B, Sun X, Mei H, Wang Y, Liao Z, Chen J, Zhang Q, Hu Y, Pang Z and Jiang X (2013) LDLR-mediated peptide-22-conjugated nanoparticles for dual-targeting therapy of brain glioma. Biomaterials 34, 9171-9182. //www.sciencedirect.com/science/article/pii/S0142961213009873

Zhang L, Marrano P, Kumar S, Leadley M, Elias E, Thorner P and Baruchel S (2013) Nab-Paclitaxel Is an Active Drug in Preclinical Model of Pediatric Solid Tumors. Clin. Cancer Res. 19, 5972-5983. http://clincancerres.aacrjournals.org/cgi/content/abstract/19/21/5972

Zhou J, Zhao W-Y, Ma X, Ju R-J, Li X-Y, Li N, Sun M-G, Shi J-F, Zhang C-X and Lu W-L (2013) The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer. Biomaterials 34, 3626-3638. //www.sciencedirect.com/science/article/pii/S0142961213001191

(2012) Index. In Natural Products in Chemical Biology. (Ed.^(Eds  pp. 389-425. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.index

(2012) Author Index. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 383-401. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444538369000281

(2012) Subject Index. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 377-404. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444595140180010

(2012) Index. In Handbook of Clinical Neurology. (Ed.^(Eds Wolfgang G and Riccardo S) pp. I1-I16. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444535023000343

(2012) Index. In Comprehensive Chiroptical Spectroscopy. (Ed.^(Eds  pp. 843-853. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118120392.index

Ang ESM, Pavlos NJ, Chim SM, Feng HT, Scaife RM, Steer JH, Zheng MH and Xu J (2012) Paclitaxel inhibits osteoclast formation and bone resorption via influencing mitotic cell cycle arrest and RANKL-induced activation of NF-κB and ERK. Journal of Cellular Biochemistry 113, 946-955. http://dx.doi.org/10.1002/jcb.23423

Ben-Arye E, Schiff E, Hassan E, Mutafoglu K, Lev-Ari S, Steiner M, Lavie O, Polliack A, Silbermann M and Lev E (2012) Integrative oncology in the Middle East: from traditional herbal knowledge to contemporary cancer care. Ann. Onc. 23, 211-221. http://annonc.oxfordjournals.org/cgi/content/abstract/23/1/211

Bouchard H, Semiond D, Risse M-L and Vrignaud P (2012) Novel Taxanes: Cabazitaxel Case Study. In Analogue-Based Drug Discovery III. (Ed.^(Eds  pp. 319-341. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527651085.ch13

Brody T (2012) Chapter 1 - The Origins of Drugs. In Clinical Trials. (Ed.^(Eds  pp. 1-15. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780123919113000013

Burrows GE and Tyrl RJ (2012) Taxaceae A.Gray. In Toxic Plants of North America. (Ed.^(Eds  pp. 1177-1185. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781118413425.ch70

Calcul L, Zhang B, Jinwal U, Dickey C and Baker B (2012) Natural products as a rich source of tau-targeting drugs for Alzheimers disease. Future Med Chem 4, 1751-61.

Campos SM and Dizon DS (2012) Antimitotic Inhibitors. Hematology/Oncology Clinics of North America 26, 607-628. http://www.sciencedirect.com/science/article/pii/S0889858812000081

Caron J, Maksimenko A, Wack S, Lepeltier E, Bourgaux C, Morvan E, Leblanc K, Couvreur P and Desmaële D (2012) Improving the Antitumor Activity of Squalenoyl-Paclitaxel Conjugate Nanoassemblies by Manipulating the Linker between Paclitaxel and Squalene. Advanced Healthcare Materials, n/a-n/a. http://dx.doi.org/10.1002/adhm.201200099

Cha M, Shim S, Kim S, Kim O, Lee S, Kwon S and Baek K (2012) Production of taxadiene from cultured ginseng roots transformed with taxadiene synthase gene. BMB Rep 45, 589-94.

Chen M, Shao Z and Chen X (2012) Paclitaxel-loaded silk fibroin nanospheres. Journal of Biomedical Materials Research Part A 100A, 203-210. http://dx.doi.org/10.1002/jbm.a.33265

Chen W, Shen Y, Rong H, Lei L and Guo S (2012) Development and application of a validated gradient elution HPLC method for simultaneous determination of 5-fluorouracil and paclitaxel in dissolution samples of 5-fluorouracil/paclitaxel-co-eluting stents. Journal of Pharmaceutical and Biomedical Analysis 59, 179-183. http://www.sciencedirect.com/science/article/pii/S0731708511005814

Chuang J-C, Sheu G-T, Wang P-C, Liao F-T, Liu W-S, Huang C-F, Tseng M-H and Wu M-F (2012) Docetaxel and 5-fluorouracil induce human p53 tumor suppressor gene transcription via a short sequence at core promoter element. Toxicology in Vitro 26, 678-685. http://www.sciencedirect.com/science/article/pii/S0887233312000653

Cieckiewicz E, Angenot L, Gras T, Kiss R and Frédérich M (2012) Potential anticancer activity of young Carpinus betulus leaves. Phytomedicine 19, 278-283. http://www.sciencedirect.com/science/article/pii/S0944711311004600

Cortese B and Bertoletti A (2012) Paclitaxel coated balloons for coronary artery interventions: A comprehensive review of preclinical and clinical data. International Journal of Cardiology 161, 4-12. //www.sciencedirect.com/science/article/pii/S0167527311017116

Cui Y, Yi D, Bai X, Sun B, Zhao Y and Zhang Y (2012) Ginkgolide B produced endophytic fungus (Fusarium oxysporum) isolated from Ginkgo biloba. Fitoterapia 83, 913-920. http://www.sciencedirect.com/science/article/pii/S0367326X12001165

Dahmani FZ, Yang H, Zhou J, Yao J, Zhang T and Zhang Q (2012) Enhanced oral bioavailability of paclitaxel in pluronic/LHR mixed polymeric micelles: Preparation, in vitro and in vivo evaluation. European Journal of Pharmaceutical Sciences 47, 179-189. http://www.sciencedirect.com/science/article/pii/S0928098712002424

Danhier F, Pourcelle V, Marchand-Brynaert J, Jérôme C, Feron O and Préat V (2012) Chapter eight - Targeting of Tumor Endothelium by RGD-Grafted PLGA-Nanoparticles. In Methods in Enzymology. (Ed.^(Eds Nejat D) pp. 157-175. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123918604000082

De Andrés Del Rosario A, Almagro Sánchez M, Rosende Maceiras L and Fonseca Capdevila E (2012) Sarcoma de Kaposi parte II: tratamiento. Piel 27, 243-252. http://www.sciencedirect.com/science/article/pii/S0213925111004618

Deshpande A, Dhadi SR, Hager EJ and Ramakrishna W (2012) Anticancer Activity of Rice Callus Suspension Culture. Phytotherapy Research 26, 1075-1081. http://dx.doi.org/10.1002/ptr.3699

Dupont F and Guignard J-L (2012) 8 - Classe des Gymnospermes ou Plantes ŕ ovules nus. In Botanique (15e édition). (Ed.^(Eds  pp. 46-60. (Elsevier Masson: Paris). //www.sciencedirect.com/science/article/pii/B9782294714269000087

Eisenberger MA and Antonarakis ES (2012) The Experience with Cytotoxic Chemotherapy in Metastatic Castration-Resistant Prostate Cancer. Urologic Clinics of North America 39, 573-581. //www.sciencedirect.com/science/article/pii/S0094014312000730

Eisenhauer EL, Salani R and Copeland LJ (2012) Chapter 11 - Epithelial Ovarian Cancer. In Clinical Gynecologic Oncology (Eighth Edition). (Ed.^(Eds  pp. 285-328. (Mosby: Philadelphia). http://www.sciencedirect.com/science/article/pii/B9780323074193000114

Eisenhauer EL, Salani R and Copeland LJ (2012) Chapter 11 - Epithelial Ovarian Cancer A2 - Saia, Philip J. Di. In Clinical Gynecologic Oncology (Eighth Edition). (Ed.^(Eds Creasman WT) pp. 285-328.e12. (Mosby: Philadelphia). //www.sciencedirect.com/science/article/pii/B9780323074193000114

Elavarasi A, Rathna GS and Kalaiselvam M (2012) Taxol producing mangrove endophytic fungi Fusarium oxysporum from Rhizophora annamalayana. Asian Pacific Journal of Tropical Biomedicine 2, S1081-S1085. //www.sciencedirect.com/science/article/pii/S2221169112603657

Fred Wong WS (2012) Introduction. Clinical and Experimental Pharmacology and Physiology 39, 253-255. http://dx.doi.org/10.1111/j.1440-1681.2012.05682.x

Friedmann DR, Aguilar A, Fan J, Nachury MV and Marmorstein R (2012) Structure of the {alpha}-tubulin acetyltransferase, {alpha}TAT1, and implications for tubulin-specific acetylation. PNAS 109, 19655-19660. http://www.pnas.org/cgi/content/abstract/109/48/19655

Galata M and Mahmoud S (2012) Chapter 5 - Bioactive Plant Isoprenoids: Biosynthetic and Biotechnological Approaches. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 135-171. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444595140000055

Genis D, Kirpichenok M and Kombarov R (2012) A minimalist fragment approach for the design of natural-product-like synthetic scaffolds. Drug Discovery Today 17, 1170-1174. //www.sciencedirect.com/science/article/pii/S1359644612001900

Gond SK, Mishra A, Sharma VK, Verma SK, Kumar J, Kharwar RN and Kumar A (2012) Diversity and antimicrobial activity of endophytic fungi isolated from Nyctanthes arbor-tristis, a well-known medicinal plant of India. Mycoscience 53, 113-121. //www.sciencedirect.com/science/article/pii/S1340354012700165

Gouvea DR, Gobbo-Neto L and Lopes NP (2012) The Influence of Biotic and Abiotic Factors on the Production of Secondary Metabolites in Medicinal Plants. In Plant Bioactives and Drug Discovery. (Ed.^(Eds  pp. 419-452. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118260005.ch12

Gray AN, Spies TA and Pabst RJ (2012) Canopy gaps affect long-term patterns of tree growth and mortality in mature and old-growth forests in the Pacific Northwest. Forest Ecology and Management 281, 111-120. http://www.sciencedirect.com/science/article/pii/S0378112712003647

Green S, Brasier CM, Schlenzig A, McCracken A, MacAskill GA, Wilson M and Webber JF (2012) The destructive invasive pathogen Phytophthora lateralis found on Chamaecyparis lawsoniana across the UK. Forest Pathology, n/a-n/a. http://dx.doi.org/10.1111/j.1439-0329.2012.00788.x

Grobosch T, Schwarze B, Stoecklein D and Binscheck T (2012) Fatal poisoning with Taxus baccata. Quantification of Paclitaxel (taxol A), 10-Deacetyltaxol, Baccatin III, 10-Deacetylbaccatin III, Cephalomannine (taxol B), and 3,5-Dimethoxyphenol in Body Fluids by Liquid Chromatography-Tandem Mass Spectrometry. J Anal Toxicol 36, 36-43. http://jat.oxfordjournals.org/cgi/content/abstract/36/1/36

Gruwez R, Leroux O, De Frenne P, Tack W, Viane R and Verheyen K (2012) Critical phases in the seed development of common juniper (Juniperus communis). Plant Biology, no-no. http://dx.doi.org/10.1111/j.1438-8677.2012.00628.x

Gunatilaka AL (2012) Plant Natural Products. In Natural Products in Chemical Biology. (Ed.^(Eds  pp. 1-29. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch1

Hackenberg S, Scherzed A, Harnisch W, Froelich K, Ginzkey C, Koehler C, Hagen R and Kleinsasser N (2012) Antitumor activity of photo-stimulated zinc oxide nanoparticles combined with paclitaxel or cisplatin in HNSCC cell lines. Journal of Photochemistry and Photobiology B: Biology 114, 87-93. http://www.sciencedirect.com/science/article/pii/S1011134412001091

Ham Y-M, Yoon W-J, Park S-Y, Jung Y-H, Kim D, Jeon Y-J, Wijesinghe WAJP, Kang S-M and Kim K-N (2012) Investigation of the component of Lycopodium serratum extract that inhibits proliferation and mediates apoptosis of human HL-60 leukemia cells. Food and Chemical Toxicology 50, 2629-2634. http://www.sciencedirect.com/science/article/pii/S0278691512003626

Hamann A and Aitken SN (2012) Conservation planning under climate change: accounting for adaptive potential and migration capacity in species distribution models. Diversity and Distributions, n/a-n/a. http://dx.doi.org/10.1111/j.1472-4642.2012.00945.x

Hammerschmidt L, Wray V, Lin W, Kamilova E, Proksch P and Aly AH (2012) New styrylpyrones from the fungal endophyte Penicillium glabrum isolated from Punica granatum. Phytochemistry Letters 5, 600-603. //www.sciencedirect.com/science/article/pii/S1874390012001164

Hao D-C, Xiao P-G, Ge G-B and Liu M (2012) Biological, Chemical, and Omics Research of Taxus Medicinal Resources. Drug Development Research 73, 477-486. http://dx.doi.org/10.1002/ddr.21040

Hartley RM, Peng J, Fest GA, Dakshanamurthy S, Frantz DE, Brown ML and Mooberry SL (2012) Polygamain, a New Microtubule Depolymerizing Agent That Occupies a Unique Pharmacophore in the Colchicine Site. Mol. Pharmacol. 81, 431-439. http://molpharm.aspetjournals.org/cgi/content/abstract/81/3/431

Hazalin NAMN, Ramasamy K, Lim SM, Cole ALJ and Majeed ABA (2012) Induction of apoptosis against cancer cell lines by four ascomycetes (endophytes) from Malaysian rainforest. Phytomedicine 19, 609-617. http://www.sciencedirect.com/science/article/pii/S0944711312000396

Heck T, Geueke B and Kohler H-PE (2012) Bacterial β-Aminopeptidases: Structural Insights and Applications for Biocatalysis. Chemistry & Biodiversity 9, 2388-2409. http://dx.doi.org/10.1002/cbdv.201200305

Hendrawati O, Woerdenbag HJ, Hille J and Kayser O (2012) Metabolic Engineering of Medicinal Plants and Microorganisms for the Production of Natural Products. In Pharmaceutical Biotechnology. (Ed.^(Eds  pp. 491-526. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527632909.ch19

Hendrikx JJMA, Lagas JS, Rosing H, Schellens JHM, Beijnen JH and Schinkel AH (2012) P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel. International Journal of Cancer, n/a-n/a. http://dx.doi.org/10.1002/ijc.27912

Hodgson E (2012) Chapter Fourteen - Toxins and Venoms. In Progress in Molecular Biology and Translational Science. (Ed.^(Eds Ernest H) pp. 373-415. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780124158139000143

Honda H, Nagai Y, Matsunaga T, Saitoh S-i, Akashi-Takamura S, Hayashi H, Fujii I, Miyake K, Muraguchi A and Takatsu K (2012) Glycyrrhizin and isoliquiritigenin suppress the LPS sensor Toll-like receptor 4/MD-2 complex signaling in a different manner. J. Leukoc. Biol. 91, 967-976. http://www.jleukbio.org/cgi/content/abstract/91/6/967

Hu Q, Li W, Hu X, Hu Q, Shen J, Jin X, Zhou J, Tang G and Chu PK (2012) Synergistic treatment of ovarian cancer by co-delivery of survivin shRNA and paclitaxel via supramolecular micellar assembly. Biomaterials 33, 6580-6591. http://www.sciencedirect.com/science/article/pii/S014296121200614X

Ilisz I, Aranyi A, Pataj Z and Péter A (2012) Enantiomeric separation of nonproteinogenic amino acids by high-performance liquid chromatography. Journal of Chromatography A 1269, 94-121. //www.sciencedirect.com/science/article/pii/S002196731201045X

Inamdar SR, Savanur MA, Eligar SM, Chachadi VB, Nagre NN, Chen C, Barclays M, Ingle A, Mahajan P, Borges A, Shastry P, Kalraiya RD, Swamy BM, Rhodes JM and Yu L-G (2012) The TF-antigen binding lectin from Sclerotium rolfsii inhibits growth of human colon cancer cells by inducing apoptosis in vitro and suppresses tumor growth in vivo. Glycobiology 22, 1227-1235. http://glycob.oxfordjournals.org/cgi/content/abstract/22/9/1227

Jensen KH, Liesche J, Bohr T and Schulz A (2012) Universality of phloem transport in seed plants. Plant, Cell & Environment 35, 1065-1076. http://dx.doi.org/10.1111/j.1365-3040.2011.02472.x

Jiang M, Stephanopoulos G and Pfeifer B (2012) Downstream reactions and engineering in the microbially reconstituted pathway for Taxol. Appl Microbiol Biotechnol 94, 841-9.

Jiang M, Stephanopoulos G and Pfeifer BA (2012) Toward Biosynthetic Design and Implementation of Escherichia coli-Derived Paclitaxel and Other Heterologous Polyisoprene Compounds. Appl. Envir. Microbiol. 78, 2497-2504. http://aem.asm.org/cgi/content/abstract/78/8/2497

Jiang M, Stephanopoulos G and Pfeifer BA (2012) Downstream reactions and engineering in the microbially reconstituted pathway for Taxol. Applied microbiology and biotechnology.. 94, 841-849. http://dx.doi.org/10.1007/s00253-012-4016-1

Kajani AA, Moghim S and Mofid MR (2012) Enhanced taxane production and secretion from Taxus baccata cell culture by adding dimethylsulfoxide. Biotechnology and Applied Biochemistry 59, 223-227. http://dx.doi.org/10.1002/bab.1017

Kamath A and Ojima I (2012) Advances in the chemistry of β-lactam and its medicinal applications. Tetrahedron 68, 10640-10664. //www.sciencedirect.com/science/article/pii/S0040402012011854

Keeling CI and Bohlmann J (2012) Plant Terpenoids. In Natural Products in Chemical Biology. (Ed.^(Eds  pp. 127-142. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch5

Kelber O, Steinhoff B and Kraft K (2012) Assessment of genotoxicity of herbal medicinal products: A co-ordinated approach. Phytomedicine 19, 472-476. http://www.sciencedirect.com/science/article/pii/S0944711311005332

Khan W, Farah S and Domb AJ (2012) Drug eluting stents: Developments and current status. Journal of Controlled Release 161, 703-712. http://www.sciencedirect.com/science/article/pii/S0168365912000879

Kim M-S, Stewart JE, Dumroese RK and Klopfenstein NB (2012) Occurrence of the Root Rot Pathogen, Fusarium commune, in Forest Nurseries of?the Midwestern and Western United States. Journal of Phytopathology 160, 112-114. http://dx.doi.org/10.1111/j.1439-0434.2011.01865.x

Kingston DGI and Newman DJ (2012) Natural Products as Anticancer Agents. In Natural Products in Chemical Biology. (Ed.^(Eds  pp. 325-349. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch13

Kirschning A and Hahn F (2012) Vereinigung von chemischer Synthese und Biosynthese: ein neues Kapitel in der Totalsynthese von Naturstoffen und Naturstoffbibliotheken. Angewandte Chemie 124, 4086-4096. http://dx.doi.org/10.1002/ange.201107386

Kirschning A and Hahn F (2012) Merging Chemical Synthesis and Biosynthesis: A New Chapter in the Total Synthesis of Natural Products and Natural Product Libraries. Angewandte Chemie International Edition 51, 4012-4022. http://dx.doi.org/10.1002/anie.201107386

Koskinen AMP (2012) Alkaloids. In Asymmetric Synthesis of Natural Products. (Ed.^(Eds  pp. 257-287. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118347300.ch10

Koskinen AMP (2012) Index. In Asymmetric Synthesis of Natural Products. (Ed.^(Eds  pp. 289-306. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118347300.index

Kraitzer A, Alperstein D, Kloog Y and Zilberman M (2012) Mechanisms of antiproliferative drug release from bioresorbable porous structures. Journal of Biomedical Materials Research Part A, n/a-n/a. http://dx.doi.org/10.1002/jbm.a.34436

Lange BM and Ahkami A (2012) Metabolic engineering of plant monoterpenes, sesquiterpenes and diterpenes—current status and future opportunities. Plant Biotechnology Journal, n/a-n/a. http://dx.doi.org/10.1111/pbi.12022

Leandro-Garcia LJ, Leskela S, Jara C, Green H, Avall-Lundqvist E, Wheeler HE, Dolan ME, Inglada-Perez L, Maliszewska A, de Cubas AA, Comino-Mendez I, Mancikova V, Cascon A, Robledo M and Rodriguez-Antona C (2012) Regulatory Polymorphisms in {beta}-Tubulin IIa Are Associated with Paclitaxel-Induced Peripheral Neuropathy. Clin. Cancer Res. 18, 4441-4448. http://clincancerres.aacrjournals.org/cgi/content/abstract/18/16/4441

Lee K-H, Itokawa H, Akiyama T and Morris-Natschke SL (2012) Plant-Derived Natural Products Research in Drug Discovery. In Natural Products in Chemical Biology. (Ed.^(Eds  pp. 351-388. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch14

Lee W-L, Shiau J-Y and Shyur L-F (2012) Chapter 4 - Taxol, Camptothecin and Beyond for Cancer Therapy. In Advances in Botanical Research. (Ed.^(Eds Lie-Fen S and Allan SYL) pp. 133-178. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123945914000088

Lee W-L, Shiau J-Y and Shyur L-F (2012) Taxol, Camptothecin and Beyond for Cancer Therapy. Advances in Botanical Research., 62. http://dx.doi.org/10.1016/B978-0-12-394591-4.00008-8

Lee W-L and Shyur L-F (2012) Deoxyelephantopin impedes mammary adenocarcinoma cell motility by inhibiting calpain-mediated adhesion dynamics and inducing reactive oxygen species and aggresome formation. Free Radical Biology and Medicine 52, 1423-1436. http://www.sciencedirect.com/science/article/pii/S0891584912000640

Leslie AB, Beaulieu JM, Rai HS, Crane PR, Donoghue MJ and Mathews S (2012) Hemisphere-scale differences in conifer evolutionary dynamics. PNAS 109, 16217-16221. http://www.pnas.org/cgi/content/abstract/109/40/16217

Levy SM (2012) Section 7 - Lumber—Calculations to Select Framing and Trim Materials. In Construction Calculations Manual. (Ed.^(Eds  pp. 351-440. (Butterworth-Heinemann: Boston). http://www.sciencedirect.com/science/article/pii/B9780123822437000115

Li G, Kollner TG, Yin Y, Jiang Y, Chen H, Xu Y, Gershenzon J, Pichersky E and Chen F (2012) Nonseed plant Selaginella moellendorffii has both seed plant and microbial types of terpene synthases. PNAS 109, 14711-14715. http://www.pnas.org/cgi/content/abstract/109/36/14711

Li L, Kim JK, Huh KM, Lee Y-k and Kim SY (2012) Targeted delivery of paclitaxel using folate-conjugated heparin-poly(β-benzyl-l-aspartate) self-assembled nanoparticles. Carbohydrate Polymers 87, 2120-2128. http://www.sciencedirect.com/science/article/pii/S0144861711009362

Li S, Zhang P, Zhang M, Fu C and Yu L (2012) Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biology, no-no. http://dx.doi.org/10.1111/j.1438-8677.2012.00611.x

Liang L, Lin S-W, Dai W, Lu J-K, Yang T-Y, Xiang Y, Zhang Y, Li R-T and Zhang Q (2012) Novel cathepsin B-sensitive paclitaxel conjugate: Higher water solubility, better efficacy and lower toxicity. Journal of Controlled Release 160, 618-629. http://www.sciencedirect.com/science/article/pii/S0168365912001459

Lim J and Simanek EE (2012) Triazine dendrimers as drug delivery systems: From synthesis to therapy. Advanced Drug Delivery Reviews 64, 826-835. http://www.sciencedirect.com/science/article/pii/S0169409X12001044

Loh XJ, Yee BJH and Chia FS (2012) Sustained delivery of paclitaxel using thermogelling poly(PEG/PPG/PCL urethane)s for enhanced toxicity against cancer cells. Journal of Biomedical Materials Research Part A, n/a-n/a. http://dx.doi.org/10.1002/jbm.a.34198

Lohr M, Schwender J and Polle JEW (2012) Isoprenoid biosynthesis in eukaryotic phototrophs: A spotlight on algae. Plant Science 185–186, 9-22. http://www.sciencedirect.com/science/article/pii/S0168945211002202

Lu F, Shen Y-Y, Shen Y-Q, Hou J-W, Wang Z-M and Guo S-R (2012) Treatments of paclitaxel with poly(vinyl pyrrolidone) to improve drug release from poly(ɛ-caprolactone) matrix for film-based stent. International Journal of Pharmaceutics 434, 161-168. http://www.sciencedirect.com/science/article/pii/S0378517312005431

Lv Y, Song Q, Shao Q, Gao W, Mao H, Lou H, Qu X and Li X (2012) Comparison of the effects of marchantin C and fucoidan on sFlt-1 and angiogenesis in glioma microenvironment. Journal of Pharmacy and Pharmacology 64, 604-609. http://dx.doi.org/10.1111/j.2042-7158.2011.01430.x

Manosroi J, Sainakham M, Manosroi W and Manosroi A (2012) Anti-proliferative and apoptosis induction activities of extracts from Thai medicinal plant recipes selected from MANOSROI II database. Journal of Ethnopharmacology 141, 451-459. http://www.sciencedirect.com/science/article/pii/S0378874112001584

Mase N (2012) 6.4 C–C Bond Formation: Aldol Reaction with Proline Derivatives. In Comprehensive Chirality. (Ed.^(Eds  pp. 97-124. (Elsevier: Amsterdam). //www.sciencedirect.com/science/article/pii/B9780080951676006042

McPartland TJ, Patil RA, Malone MF and Roberts SC (2012) Liquid–liquid extraction for recovery of paclitaxel from plant cell culture: Solvent evaluation and use of extractants for partitioning and selectivity. Biotechnology Progress, n/a-n/a. http://dx.doi.org/10.1002/btpr.1562

Messier MS, Shatford JPA and Hibbs DE (2012) Fire exclusion effects on riparian forest dynamics in southwestern Oregon. Forest Ecology and Management 264, 60-71. http://www.sciencedirect.com/science/article/pii/S0378112711006050

Miele M, Mumot AM, Zappa A, Romano P and Ottaggio L (2012) Hazel and other sources of paclitaxel and related compounds. Phytochemistry reviews. 11, 211-225. http://dx.doi.org/10.1007/s11101-012-9234-8

Mirjalili MH, Farzaneh M, Bonfill M, Rezadoost H and Ghassempour A (2012) Isolation and characterization of Stemphylium sedicola SBU-16 as a new endophytic taxol-producing fungus from Taxus baccata grown in Iran. FEMS Microbiology Letters 328, 122-129. http://dx.doi.org/10.1111/j.1574-6968.2011.02488.x

Mirjalili MH, Farzaneh M, Bonfill M, Rezadoost H and Ghassempour A (2012) Isolation and characterization of Stemphylium sedicola SBU-16 as a new endophytic taxol-producing fungus from Taxus baccata grown in Iran. FEMS Microbiol Lett 328, 122-129. http://femsle.oxfordjournals.org/cgi/content/abstract/328/2/122

Mo M, Erdelyi I, Szigeti-Buck K, Benbow JH and Ehrlich BE (2012) Prevention of paclitaxel-induced peripheral neuropathy by lithium pretreatment. FASEB J 26, 4696-4709. http://www.fasebj.org/cgi/content/abstract/26/11/4696

MOSBY TT, COSGROVE M, SARKARDEI S, PLATT KL and KAINA B (2012) Nutrition in Adult and Childhood Cancer: Role of Carcinogens and Anti-carcinogens. Anticancer Res 32, 4171-4192. http://ar.iiarjournals.org/cgi/content/abstract/32/10/4171

Muńoz Solano D, Hoyos P, Hernáiz MJ, Alcántara AR and Sánchez-Montero JM (2012) Industrial biotransformations in the synthesis of building blocks leading to enantiopure drugs. Bioresource Technology 115, 196-207. http://www.sciencedirect.com/science/article/pii/S0960852411017421

Murray S, Briasoulis E, Linardou H, Bafaloukos D and Papadimitriou C (2012) Taxane resistance in breast cancer: Mechanisms, predictive biomarkers and circumvention strategies. Cancer Treatment Reviews 38, 890-903. //www.sciencedirect.com/science/article/pii/S0305737212000497

Naciri Y, Caetano S and Salamin N (2012) Plant DNA barcodes and the influence of gene flow. Molecular Ecology Resources 12, 575-580. http://dx.doi.org/10.1111/j.1755-0998.2012.03130.x

Naill MC, Kolewe ME and Roberts SC (2012) Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochemical Engineering Journal 63, 50-56. http://www.sciencedirect.com/science/article/pii/S1369703X12000125

Nicolaou KC, Hale CRH and Nilewski C (2012) A total synthesis trilogy: Calicheamicin γ1I, Taxol®, and brevetoxin A. The Chemical Record, n/a-n/a. http://dx.doi.org/10.1002/tcr.201200005

OCathail S and Stebbing J (2012) Ayurveda: alternative or complementary? The Lancet Oncology 13, 865. //www.sciencedirect.com/science/article/pii/S1470204512704059

Oh H-J, Jang HR, Jung KY and Kim J-H (2012) Evaluation of adsorbents for separation and purification of paclitaxel from plant cell cultures. Process Biochemistry 47, 331-334. http://www.sciencedirect.com/science/article/pii/S1359511311004016

Park JH, Park JH, Hur HJ, Woo JS and Lee HJ (2012) Effects of silymarin and formulation on the oral bioavailability of paclitaxel in rats. European Journal of Pharmaceutical Sciences 45, 296-301. http://www.sciencedirect.com/science/article/pii/S0928098711004283

Park SH, Kim ND, Jung J-K, Lee C-K, Han S-B and Kim Y (2012) Myeloid differentiation 2 as a therapeutic target of inflammatory disorders. Pharmacology &amp; Therapeutics 133, 291-298. http://www.sciencedirect.com/science/article/pii/S0163725811002038

Park SH, Kim ND, Jung J-K, Lee C-K, Han S-B and Kim Y (2012) Myeloid differentiation 2 as a therapeutic target of inflammatory disorders. Pharmacology & Therapeutics 133, 291-298. //www.sciencedirect.com/science/article/pii/S0163725811002038

Polavarapu PL (2012) Determination of the Structures of Chiral Natural Products Using Vibrational Circular Dichroism. In Comprehensive Chiroptical Spectroscopy. (Ed.^(Eds  pp. 387-420. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118120392.ch11

Postma TJ and Heimans JJ (2012) Chapter 60 - Neurological complications of chemotherapy to the peripheral nervous system. In Handbook of Clinical Neurology. (Ed.^(Eds Wolfgang G and Riccardo S) pp. 917-936. (Elsevier). http://www.sciencedirect.com/science/article/pii/B978044453502300032X

Pourmohammadi N, Alimoradi H, Mehr SE, Hassanzadeh G, Hadian MR, Sharifzadeh M, Bakhtiarian A and Dehpour AR (2012) Lithium Attenuates Peripheral Neuropathy Induced by Paclitaxel in Rats. Basic & Clinical Pharmacology & Toxicology 110, 231-237. http://dx.doi.org/10.1111/j.1742-7843.2011.00795.x

Prado S, Li Y and Nay B (2012) Chapter 8 - Diversity and Ecological Significance of Fungal Endophyte Natural Products. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 249-296. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444538369000256

Prasad KR and Gutala P (2012) Total synthesis of (+)-phomopsolide B. Tetrahedron 68, 7489-7493. http://www.sciencedirect.com/science/article/pii/S0040402012008824

Qi J, Zhao J and Kingston DGI (2012) Recent Progress in the Chemistry and Biology of Paclitaxel (TaxolTM) and Related Taxanes. In Plant Bioactives and Drug Discovery. (Ed.^(Eds  pp. 263-336. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118260005.ch8

Rathee P, Rathee D, Rathee D and Rathee S (2012) In-vitro cytotoxic activity of β-Sitosterol triacontenate isolated from Capparis decidua (Forsk.) Edgew. Asian Pacific Journal of Tropical Medicine 5, 225-230. http://www.sciencedirect.com/science/article/pii/S1995764512600297

Rodriguez G, Fernandez-Gutierrez M, Parra J, Lopez-Bravo A, Molina M, Duocastella L and San Roman J (2012) Bioactive coatings for coronary stents: Modulation of cell proliferation by controlled release of anti-proliferative drugs. Journal of Bioactive and Compatible Polymers 27, 550-564. http://jbc.sagepub.com/cgi/content/abstract/27/6/550

Rodríguez J, Castańeda G, Contento AM and Muńoz L (2012) Direct and fast determination of paclitaxel, morphine and codeine in urine by micellar electrokinetic chromatography. Journal of Chromatography A 1231, 66-72. http://www.sciencedirect.com/science/article/pii/S0021967312002312

Rukachaisirikul V, Rodglin A, Phongpaichit S, Buatong J and Sakayaroj J (2012) α-Pyrone and seiricuprolide derivatives from the mangrove-derived fungi Pestalotiopsis spp. PSU-MA92 and PSU-MA119. Phytochemistry Letters 5, 13-17. http://www.sciencedirect.com/science/article/pii/S1874390011001078

Sarpietro MG, Ottimo S, Paolino D, Ferrero A, Dosio F and Castelli F (2012) Squalenoyl prodrug of paclitaxel: Synthesis and evaluation of its incorporation in phospholipid bilayers. International Journal of Pharmaceutics 436, 135-140. http://www.sciencedirect.com/science/article/pii/S0378517312006321

Siddiqui MS, Thodey K, Trenchard I and Smolke CD (2012) Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools. FEMS Yeast Research 12, 144-170. http://dx.doi.org/10.1111/j.1567-1364.2011.00774.x

Siddiqui MS, Thodey K, Trenchard I and Smolke CD (2012) Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools. FEMS Yeast Res 12, 144-170. http://femsyr.oxfordjournals.org/cgi/content/abstract/12/2/144

Sim HA, Lee J-Y and Kim J-H (2012) Evaluation of a high surface area acetone/pentane precipitation process for the purification of paclitaxel from plant cell cultures. Separation and Purification Technology 89, 112-116. http://www.sciencedirect.com/science/article/pii/S1383586612000421

Singh SB (2012) Pharmaceuticals: Natural Products and Natural Product Models. In Natural Products in Chemical Biology. (Ed.^(Eds  pp. 287-324. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch12

Singh SB (2012) Pharmaceuticals: Natural Products and Natural Product Models. In Chemical Biology. (Ed.^(Eds  pp. 165-201. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118435762.ch10

Skrzypczak-Pietraszek E and Pietraszek J (2012) Chemical profile and seasonal variation of phenolic acid content in bastard balm (Melittis melissophyllum L., Lamiaceae). Journal of Pharmaceutical and Biomedical Analysis 66, 154-161. http://www.sciencedirect.com/science/article/pii/S0731708512001604

Sun J, Awakawa T, Noguchi H and Abe I (2012) Induced production of mycotoxins in an endophytic fungus from the medicinal plant Datura stramonium L. Bioorganic & Medicinal Chemistry Letters 22, 6397-6400. //www.sciencedirect.com/science/article/pii/S0960894X12010748

Talwar PS, Gupta R, Maurya AK and Deswal R (2012) Brassica juncea nitric oxide synthase like activity is stimulated by PKC activators and calcium suggesting modulation by PKC-like kinase. Plant Physiology and Biochemistry 60, 157-164. //www.sciencedirect.com/science/article/pii/S0981942812002240

Taylor P, Arsenak M, Abad MJ, Fernández Á, Milano B, Gonto R, Ruiz M-C, Fraile S, Taylor S, Estrada O and Michelangeli F (2012) Screening of Venezuelan medicinal plant extracts for cytostatic and cytotoxic activity against tumor cell lines. Phytotherapy Research, n/a-n/a. http://dx.doi.org/10.1002/ptr.4752

Thiel P, Kaiser M and Ottmann C (2012) Niedermolekulare Stabilisatoren von Protein-Protein-Wechselwirkungen: ein unterschätztes Konzept in der Wirkstoffentwicklung? Angewandte Chemie 124, 2052-2059. http://dx.doi.org/10.1002/ange.201107616

Thiel P, Kaiser M and Ottmann C (2012) Small-Molecule Stabilization of Protein–Protein Interactions: An Underestimated Concept in Drug Discovery? Angewandte Chemie International Edition 51, 2012-2018. http://dx.doi.org/10.1002/anie.201107616

Towne DL, Nicholl EE, Comess KM, Galasinski SC, Hajduk PJ and Abraham VC (2012) Development of a High-Content Screening Assay Panel to Accelerate Mechanism of Action Studies for Oncology Research. J Biomol Screen 17, 1005-1017. http://jbx.sagepub.com/cgi/content/abstract/17/8/1005

Urlacher VB (2012) 7.13 Oxidation: Stereoselective Oxidations with Cytochrome P450 Monooxygenases. In Comprehensive Chirality. (Ed.^(Eds  pp. 275-294. (Elsevier: Amsterdam). //www.sciencedirect.com/science/article/pii/B9780080951676007163

Valentijn JA, van Driel LF, Jansen KA, Valentijn KM and Koster AJ (2012) Toward A 3D View of Cellular Architecture: Correlative Light Microscopy and Electron Tomography. In Biomedical Imaging. (Ed.^(Eds  pp. 180-214. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118271933.ch6

Varlet V and Augsburger M (2012) Monitoring of aglycons of yew glycosides (3,5-dimethoxyphenol, myrtenol and 1-octen-3-ol) as first indicator of yew presence. Drug Testing and Analysis, n/a-n/a. http://dx.doi.org/10.1002/dta.391

Vasantha Kumar S, Srinath S and Saha RN (2012) A Simple and Rapid 3D View Method for Selective and Sensitive Determination of Paclitaxel in Micro Volume Rat Plasma by LC-Diode Array UV and Its Application to a Pharmacokinetic Study. J Chromatogr Sci 50, 259-270. http://chromsci.oxfordjournals.org/cgi/content/abstract/50/3/259

Vella-zarb L, Baisch U and Dinnebier RE (2012) Small molecule, big difference: The role of water in the crystallization of paclitaxel. Journal of Pharmaceutical Sciences, n/a-n/a. http://dx.doi.org/10.1002/jps.23404

Vennila R, Kamalraj S and Muthumary J (2012) In vitro studies on anticancer activity of fungal taxol against human breast cancer cell line MCF-7 cells. Biomedicine &amp; Aging Pathology 2, 16-18. http://www.sciencedirect.com/science/article/pii/S2210522012000020

Vennila R, Kamalraj S and Muthumary J (2012) In vitro studies on anticancer activity of fungal taxol against human breast cancer cell line MCF-7 cells. Biomedicine & Aging Pathology 2, 16-18. //www.sciencedirect.com/science/article/pii/S2210522012000020

Vennila R, Kamalraj S and Muthumary J (2012) In vitro Studies on anticancer activity of fungal taxol against human breast cancer cell line MCF-7 cells. Asian Pacific Journal of Tropical Biomedicine 2, S1159-S1161. //www.sciencedirect.com/science/article/pii/S2221169112603785

Vergara D, Bellomo C, Zhang X, Vergaro V, Tinelli A, Lorusso V, Rinaldi R, Lvov YM, Leporatti S and Maffia M (2012) Lapatinib/Paclitaxel polyelectrolyte nanocapsules for overcoming multidrug resistance in ovarian cancer. Nanomedicine: Nanotechnology, Biology and Medicine 8, 891-899. http://www.sciencedirect.com/science/article/pii/S1549963411005223

Vieira JM and Riley PR (2012) Chemical genetics and its potential in cardiac stem cell therapy. British Journal of Pharmacology, no-no. http://dx.doi.org/10.1111/j.1476-5381.2012.01928.x

von Euler H, Rivera P, Nyman H, Häggström J and Borgĺ O (2012) A dose-finding study with a novel water-soluble formulation of paclitaxel for the treatment of malignant high-grade solid tumours in dogs. Veterinary and Comparative Oncology, n/a-n/a. http://dx.doi.org/10.1111/j.1476-5829.2011.00314.x

Wakabayashi K, Mintz GS, Weissman NJ, Stone GW, Ellis SG, Grube E, Ormiston JA, Turco MA, Pakala R, Xue Z, Desale S, Laynez-Carnicero A, Romaguera R, Sardi G, Pichard AD and Waksman R (2012) Impact of Drug-Eluting Stents on Distal Vessels. Circ Cardiovasc Interv 5, 211-219. http://circinterventions.ahajournals.org/cgi/content/abstract/5/2/211

Ward OP (2012) Production of recombinant proteins by filamentous fungi. Biotechnology Advances 30, 1119-1139. //www.sciencedirect.com/science/article/pii/S0734975011001650

Wen C-C, Chen H-M and Yang N-S (2012) Chapter 6 - Developing Phytocompounds from Medicinal Plants as Immunomodulators. In Advances in Botanical Research. (Ed.^(Eds Lie-Fen S and Allan SYL) pp. 197-272. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123945914000040

Wender PA, Galliher WC, Bhat NM, Pillow TH, Bieber MM and Teng NNH (2012) Taxol-oligoarginine conjugates overcome drug resistance in-vitro in human ovarian carcinoma. Gynecologic Oncology 126, 118-123. http://www.sciencedirect.com/science/article/pii/S0090825812002508

Wiese JL, Meadow JF and Lapp JA (2012) Seed weights for northern Rocky Mountain native plants: With an Emphasis on Glacier National Park. NPJ 13, 39-50. http://npj.uwpress.org/cgi/content/abstract/13/1/39

Wilson CR and Hooser SB (2012) Chapter 82 - Toxicity of yew (Taxus spp.) alkaloids. In Veterinary Toxicology (Second Edition). (Ed.^(Eds  pp. 1121-1127. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780123859266001101

Wilson CR and Hooser SB (2012) Chapter 82 - Toxicity of yew (Taxus spp.) alkaloids A2 - Gupta, Ramesh C. In Veterinary Toxicology (Second Edition). (Ed.^(Eds  pp. 1121-1127. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780123859266001101

Wilson SA and Roberts SC (2012) Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules. Plant Biotechnology Journal 10, 249-268. http://dx.doi.org/10.1111/j.1467-7652.2011.00664.x

Wittmann A and Süß B (2012) RNA-Schalter. Biologie in unserer Zeit 42, 159-164. http://dx.doi.org/10.1002/biuz.201210477

Woo CC, Kumar AP, Sethi G and Tan KHB (2012) Thymoquinone: Potential cure for inflammatory disorders and cancer. Biochemical Pharmacology 83, 443-451. http://www.sciencedirect.com/science/article/pii/S0006295211007350

Wünschiers R, Jahn M, Jahn D, Schomburg I, Peifer S, Heinzle E, Burtscher H, Garbe J, Steen A, Schobert M, Oesterhelt D, Wachtveitl J and Chang A (2012) Metabolism. In Biochemical Pathways. (Ed.^(Eds  pp. 37-209. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118657072.ch3

Xiao Y, Liu Y and Wang G (2012) Involvement of nitric oxide in the mechanism of biochemical alterations induced by simulated microgravity in Microcystis aeruginosa. Advances in Space Research 49, 850-858. http://www.sciencedirect.com/science/article/pii/S0273117711007629

Xu B, Ding J, Chen K-X, Miao Z-H, Huang H, Liu H and Luo X-M (2012) 12 - Advances in Cancer Chemotherapeutic Drug Research in China. In Recent Advances in Cancer Research and Therapy. (Ed.^(Eds  pp. 287-350. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780123978332000121

Xu J, Ma L, Liu Y, Xu F, Nie J and Ma G (2012) Design and characterization of antitumor drug paclitaxel-loaded chitosan nanoparticles by W/O emulsions. International Journal of Biological Macromolecules 50, 438-443. http://www.sciencedirect.com/science/article/pii/S0141813011004958

Xu Q, Liu Y, Su S, Li W, Chen C and Wu Y (2012) Anti-tumor activity of paclitaxel through dual-targeting carrier of cyclic RGD and transferrin conjugated hyperbranched copolymer nanoparticles. Biomaterials 33, 1627-1639. http://www.sciencedirect.com/science/article/pii/S0142961211013500

YANG J-S, LIU C-W, MA Y-S, WENG S-W, TANG N-Y, WU S-H, JI B-C, MA C-Y, KO Y-C, FUNAYAMA S and KUO C-L (2012) Chlorogenic Acid Induces Apoptotic Cell Death in U937 Leukemia Cells through Caspase- and Mitochondria-dependent Pathways. In Vivo 26, 971-978. http://iv.iiarjournals.org/cgi/content/abstract/26/6/971

Yang L-Q, Wang B, Gan H, Fu S-T, Zhu X-X, Wu Z-N, Zhan D-W, Gu R-L, Dou G-F and Meng Z-Y (2012) Enhanced oral bioavailability and anti-tumour effect of paclitaxel by 20(s)-ginsenoside Rg3 in vivo. Biopharmaceutics & Drug Disposition 33, 425-436. http://dx.doi.org/10.1002/bdd.1806

Yang W-X, Zhao Z-G, Wang L-H, Yu S-J and Liang Z-S (2012) Control of hypertension in rats using volatile components of leaves of Taxus chinensis var. mairei. Journal of Ethnopharmacology 141, 309-313. http://www.sciencedirect.com/science/article/pii/S0378874112001213

Yao Y, Zhang B, Chen H, Chen N, Liu L, Yishan W, Li C and Zheng Q (2012) Alteronol inhibits proliferation in HeLa cells through inducing a G1-phase arrest. Journal of Pharmacy and Pharmacology 64, 101-107. http://dx.doi.org/10.1111/j.2042-7158.2011.01375.x

YE L, JI K, FREWER N, JI J and JIANG WG (2012) Impact of Yangzheng Xiaoji on the Adhesion and Migration of Human Cancer Cells: the Role of the AKT Signalling Pathway. Anticancer Res 32, 2537-2543. http://ar.iiarjournals.org/cgi/content/abstract/32/7/2537

Ye VM and Bhatia SK (2012) Metabolic engineering for the production of clinically important molecules: Omega-3 fatty acids, artemisinin, and taxol. Biotechnology Journal 7, 20-33. http://dx.doi.org/10.1002/biot.201100289

Yeung ED, Morrison A, Plumeri D, Wang J, Tong C, Yan X and Li J (2012) Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway. The Prostate 72, 165-172. http://dx.doi.org/10.1002/pros.21417

You P, Qiu J, Su E and Wei D (2012) Carica papaya Lipase Catalysed Resolution of β-Amino Esters for the Highly Enantioselective Synthesis of (S)-Dapoxetine. European Journal of Organic Chemistry, n/a-n/a. http://dx.doi.org/10.1002/ejoc.201201055

Yu J, Wang Y, Qian H, Zhao Y, Liu B and Fu C (2012) Polyprenols from the needles of Taxus chinensis var. mairei. Fitoterapia 83, 831-837. http://www.sciencedirect.com/science/article/pii/S0367326X12000342

Yuan D-m, Lv Y-l, Yao Y-w, Miao X-h, Wang Q, Xiao X-w, Yin J, Shi Y, Shi M-q, Zhang X-w and Song Y (2012) Efficacy and safety of Abraxane in treatment of progressive and recurrent non- small cell lung cancer patients: a retrospective clinical study. Thoracic Cancer, no-no. http://dx.doi.org/10.1111/j.1759-7714.2012.00113.x

Zabaleta V, Ponchel G, Salman H, Agüeros M, Vauthier C and Irache JM (2012) Oral administration of paclitaxel with pegylated poly(anhydride) nanoparticles: Permeability and pharmacokinetic study. European Journal of Pharmaceutics and Biopharmaceutics 81, 514-523. http://www.sciencedirect.com/science/article/pii/S0939641112000975

Zacharaki P, Stephanou G and Demopoulos NA (2012) Comparison of the aneugenic properties of nocodazole, paclitaxel and griseofulvin in vitro. Centrosome defects and alterations in protein expression profiles. Journal of Applied Toxicology, n/a-n/a. http://dx.doi.org/10.1002/jat.2745

Zaragoza Dörwald F (2012) Taxanes. In Lead Optimization for Medicinal Chemists. (Ed.^(Eds  pp. 554-556. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527645640.ch75

Zerbe P, Chiang A and Bohlmann J (2012) Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism. Phytochemistry 74, 30-39. http://www.sciencedirect.com/science/article/pii/S0031942211004900

Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R and Bohlmann J (2012) Bifunctional cis-Abienol Synthase from Abies balsamea Discovered by Transcriptome Sequencing and Its Implications for Diterpenoid Fragrance Production. J. Biol. Chem. 287, 12121-12131. http://www.jbc.org/cgi/content/abstract/287/15/12121

Zhang K, Li Y, Ni Z-Y, Zhang M-L, Wang Y-F, Shi Q-W, Huo C-H, Sauriol F, Kiyota H, Gu Y-C and Dong M (2012) New 6/8/6-Taxanes Isolated from the Heartwood of Taxus cuspidata. Helvetica Chimica Acta 95, 1566-1572. http://dx.doi.org/10.1002/hlca.201200045

Zhang Q, Wei X and Wang J (2012) Phillyrin produced by Colletotrichum gloeosporioides, an endophytic fungus isolated from Forsythia suspensa. Fitoterapia 83, 1500-1505. //www.sciencedirect.com/science/article/pii/S0367326X12002407

Zhao H, Li Y, Zhang X, Korpelainen H and Li C (2012) Sex-related and stage-dependent source-to-sink transition in Populus cathayana grown at elevated CO2 and elevated temperature. Tree Physiol 32, 1325-1338. http://treephys.oxfordjournals.org/cgi/content/abstract/32/11/1325

Zhao P and Astruc D (2012) Docetaxel Nanotechnology in Anticancer Therapy. ChemMedChem 7, 952-972. http://dx.doi.org/10.1002/cmdc.201200052

Zhao Y, Li J, Yu H, Wang G and Liu W (2012) Synthesis and characterization of a novel polydepsipeptide contained tri-block copolymer (mPEG–PLLA–PMMD) as self-assembly micelle delivery system for paclitaxel. International Journal of Pharmaceutics 430, 282-291. http://www.sciencedirect.com/science/article/pii/S0378517312002840

Zhou K, Gao Y, Hoy JA, Mann FM, Honzatko RB and Peters RJ (2012) Insights into Diterpene Cyclization from Structure of Bifunctional Abietadiene Synthase from Abies grandis. J. Biol. Chem. 287, 6840-6850. http://www.jbc.org/cgi/content/abstract/287/9/6840

Zonneveld BJM (2012) Conifer genome sizes of 172 species, covering 64 of 67 genera, range from 8 to 72 picogram. Nordic Journal of Botany, no-no. http://dx.doi.org/10.1111/j.1756-1051.2012.01516.x

 

 

References 1901-2013 (and links to abstracts):
[Number of papers mentioning Taxus brevifolia: 1559; Any undated papers have been included at the end]

 

Bonini SA, Ferrari-Toninelli G, Montinaro M and Memo M (2013) Notch signalling in adult neurons: a potential target for microtubule stabilization. Therapeutic Advances in Neurological Disorders 6, 375-385.  http://tan.sagepub.com/cgi/content/abstract/6/6/375

Cheng H-L, Zhao R-Y, Chen T-J, Yu W-B, Wang F, Cheng K-D and Zhu P (2013) Cloning and Characterization of the Glycoside Hydrolases That Remove Xylosyl Groups from 7-{beta}-xylosyl-10-deacetyltaxol and Its Analogues. Mol. Cell. Proteomics 12, 2236-2248.  http://www.mcponline.org/cgi/content/abstract/12/8/2236

Choudhury H, Gorain B, Karmakar S and Pal TK (2013) Development and Validation of RP-HPLC Method: Scope of Application in the Determination of Oil Solubility of Paclitaxel. J Chromatogr Sci, bms206.  http://chromsci.oxfordjournals.org/cgi/content/abstract/bms206v1

Crismaru CG, Wybenga GG, et al. (2013) Biochemical Properties and Crystal Structure of a {beta}-Phenylalanine Aminotransferase from Variovorax paradoxus. Appl. Envir. Microbiol. 79, 185-195.  http://aem.asm.org/cgi/content/abstract/79/1/185

Doran PM (2013) Chapter 1 - Bioprocess Development: An Interdisciplinary Challenge. In ‘Bioprocess Engineering Principles (Second Edition)’ (Ed.^(Eds  pp. 3-11. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780122208515000010

Gruwez R, Leroux O, De Frenne P, Tack W, Viane R and Verheyen K (2013) Critical phases in the seed development of common juniper (Juniperus communis). Plant Biology 15, 210-219.  http://dx.doi.org/10.1111/j.1438-8677.2012.00628.x

Hall DE, Zerbe P, Jancsik S, Quesada AL, Dullat H, Madilao LL, Yuen M and Bohlmann J (2013) Evolution of Conifer Diterpene Synthases: Diterpene Resin Acid Biosynthesis in Lodgepole Pine and Jack Pine Involves Monofunctional and Bifunctional Diterpene Synthases. Plant Physiology 161, 600-616.  http://www.plantphysiol.org/cgi/content/abstract/161/2/600

Iqbal J, Gunn J and Serruys PW (2013) Coronary stents: historical development, current status and future directions. Br. Med. Bull. 106, 193-211.  http://bmb.oxfordjournals.org/cgi/content/abstract/106/1/193

Jain A, Gulbake A, Jain A, Shilpi S, Hurkat P, Kashaw S and Jain SK (2013) Development and Validation of the HPLC Method for Simultaneous Estimation of Paclitaxel and Topotecan. J Chromatogr Sci, bmt101.  http://chromsci.oxfordjournals.org/cgi/content/abstract/bmt101v1

Li S, Zhang P, Zhang M, Fu C and Yu L (2013) Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biology 15, 19-26.  http://dx.doi.org/10.1111/j.1438-8677.2012.00611.x

Magallon S, Hilu KW and Quandt D (2013) Land plant evolutionary timeline: Gene effects are secondary to fossil constraints in relaxed clock estimation of age and substitution rates. Am. J. Botany 100, 556-573.  http://www.amjbot.org/cgi/content/abstract/100/3/556

Mercuri AM, Torri P, Casini E and Olmi L (2013) Climate warming and the decline of Taxus airborne pollen in urban pollen rain (Emilia Romagna, northern Italy). Plant Biology 15, 70-82.  http://dx.doi.org/10.1111/j.1438-8677.2012.00624.x

Nahata A, Saxena A, Suri N, Saxena AK and Dixit VK (2013) Sphaeranthus indicus Induces Apoptosis Through Mitochondrial-Dependent Pathway in HL-60 Cells and Exerts Cytotoxic Potential on Several Human Cancer Cell Lines. Integr Cancer Ther 12, 236-247.  http://ict.sagepub.com/cgi/content/abstract/12/3/236

Nakamura K, Shimura N, Otabe Y, Hirai-Morita A, Nakamura Y, Ono N, Ul-Amin MA and Kanaya S (2013) KNApSAcK-3D: A Three-Dimensional Structure Database of Plant Metabolites. Plant Cell Physiol. 54, e4-.  http://pcp.oxfordjournals.org/cgi/content/abstract/54/2/e4

Ramkumar K, Vijayakumar R, Vanitha P, Suganya N, Manjula C, Rajaguru P, Sivasubramanian S and Gunasekaran P (2013) Protective effect of gallic acid on alloxan-induced oxidative stress and osmotic fragility in rats. Human and Experimental Toxicology, 0960327113504792.  http://het.sagepub.com/cgi/content/abstract/0960327113504792v1

Sharma V and Sarkar IN (2013) Leveraging biodiversity knowledge for potential phyto-therapeutic applications. JAMIA 20, 668-679.  http://jamia.bmj.com/cgi/content/abstract/20/4/668

Vaughan MM, Wang Q, et al. (2013) Formation of the Unusual Semivolatile Diterpene Rhizathalene by the Arabidopsis Class I Terpene Synthase TPS08 in the Root Stele Is Involved in Defense against Belowground Herbivory. PLANT CELL 25, 1108-1125.  http://www.plantcell.org/cgi/content/abstract/25/3/1108

Zerbe P, Hamberger B, et al. (2013) Gene Discovery of Modular Diterpene Metabolism in Nonmodel Systems. Plant Physiology 162, 1073-1091.  http://www.plantphysiol.org/cgi/content/abstract/162/2/1073

Zhang L, Marrano P, Kumar S, Leadley M, Elias E, Thorner P and Baruchel S (2013) Nab-Paclitaxel Is an Active Drug in Preclinical Model of Pediatric Solid Tumors. Clin. Cancer Res. 19, 5972-5983.  http://clincancerres.aacrjournals.org/cgi/content/abstract/19/21/5972

(2012) Index. In ‘Natural Products in Chemical Biology’ (Ed.^(Eds  pp. 389-425. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.index

(2012) Author Index. In ‘Studies in Natural Products Chemistry’ (Ed.^(Eds Atta ur R) pp. 383-401. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444538369000281

(2012) Subject Index. In ‘Studies in Natural Products Chemistry’ (Ed.^(Eds Atta ur R) pp. 377-404. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444595140180010

Ang ESM, Pavlos NJ, Chim SM, Feng HT, Scaife RM, Steer JH, Zheng MH and Xu J (2012) Paclitaxel inhibits osteoclast formation and bone resorption via influencing mitotic cell cycle arrest and RANKL-induced activation of NF-κB and ERK. Journal of Cellular Biochemistry 113, 946-955.  http://dx.doi.org/10.1002/jcb.23423

Ben-Arye E, Schiff E, et al. (2012) Integrative oncology in the Middle East: from traditional herbal knowledge to contemporary cancer care. Ann. Onc. 23, 211-221.  http://annonc.oxfordjournals.org/cgi/content/abstract/23/1/211

Bouchard H, Semiond D, Risse M-L and Vrignaud P (2012) Novel Taxanes: Cabazitaxel Case Study. In ‘Analogue-Based Drug Discovery III’ (Ed.^(Eds  pp. 319-341. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527651085.ch13

Brody T (2012) Chapter 1 - The Origins of Drugs. In ‘Clinical Trials’ (Ed.^(Eds  pp. 1-15. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780123919113000013

Burrows GE and Tyrl RJ (2012) Taxaceae A.Gray. In ‘Toxic Plants of North America’ (Ed.^(Eds  pp. 1177-1185. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781118413425.ch70

Calcul L, Zhang B, Jinwal U, Dickey C and Baker B (2012) Natural products as a rich source of tau-targeting drugs for Alzheimer’s disease. Future Med Chem 4, 1751-61.

Campos SM and Dizon DS (2012) Antimitotic Inhibitors. Hematology/Oncology Clinics of North America 26, 607-628.  http://www.sciencedirect.com/science/article/pii/S0889858812000081

Caron J, Maksimenko A, Wack S, Lepeltier E, Bourgaux C, Morvan E, Leblanc K, Couvreur P and Desmaële D (2012) Improving the Antitumor Activity of Squalenoyl-Paclitaxel Conjugate Nanoassemblies by Manipulating the Linker between Paclitaxel and Squalene. Advanced Healthcare Materials, n/a-n/a.  http://dx.doi.org/10.1002/adhm.201200099

Cha M, Shim S, Kim S, Kim O, Lee S, Kwon S and Baek K (2012) Production of taxadiene from cultured ginseng roots transformed with taxadiene synthase gene. BMB Rep 45, 589-94.

Chen M, Shao Z and Chen X (2012) Paclitaxel-loaded silk fibroin nanospheres. Journal of Biomedical Materials Research Part A 100A, 203-210.  http://dx.doi.org/10.1002/jbm.a.33265

Chen W, Shen Y, Rong H, Lei L and Guo S (2012) Development and application of a validated gradient elution HPLC method for simultaneous determination of 5-fluorouracil and paclitaxel in dissolution samples of 5-fluorouracil/paclitaxel-co-eluting stents. Journal of Pharmaceutical and Biomedical Analysis 59, 179-183.  http://www.sciencedirect.com/science/article/pii/S0731708511005814

Chuang J-C, Sheu G-T, Wang P-C, Liao F-T, Liu W-S, Huang C-F, Tseng M-H and Wu M-F (2012) Docetaxel and 5-fluorouracil induce human p53 tumor suppressor gene transcription via a short sequence at core promoter element. Toxicology in Vitro 26, 678-685.  http://www.sciencedirect.com/science/article/pii/S0887233312000653

Cieckiewicz E, Angenot L, Gras T, Kiss R and Frédérich M (2012) Potential anticancer activity of young Carpinus betulus leaves. Phytomedicine 19, 278-283.  http://www.sciencedirect.com/science/article/pii/S0944711311004600

Cui Y, Yi D, Bai X, Sun B, Zhao Y and Zhang Y (2012) Ginkgolide B produced endophytic fungus (Fusarium oxysporum) isolated from Ginkgo biloba. Fitoterapia 83, 913-920.  http://www.sciencedirect.com/science/article/pii/S0367326X12001165

Dahmani FZ, Yang H, Zhou J, Yao J, Zhang T and Zhang Q (2012) Enhanced oral bioavailability of paclitaxel in pluronic/LHR mixed polymeric micelles: Preparation, in vitro and in vivo evaluation. European Journal of Pharmaceutical Sciences 47, 179-189.  http://www.sciencedirect.com/science/article/pii/S0928098712002424

Danhier F, Pourcelle V, Marchand-Brynaert J, Jérôme C, Feron O and Préat V (2012) Chapter eight - Targeting of Tumor Endothelium by RGD-Grafted PLGA-Nanoparticles. In ‘Methods in Enzymology’ (Ed.^(Eds Nejat D) pp. 157-175. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123918604000082

De Andrés Del Rosario A, Almagro Sánchez M, Rosende Maceiras L and Fonseca Capdevila E (2012) Sarcoma de Kaposi parte II: tratamiento. Piel 27, 243-252.  http://www.sciencedirect.com/science/article/pii/S0213925111004618

Deshpande A, Dhadi SR, Hager EJ and Ramakrishna W (2012) Anticancer Activity of Rice Callus Suspension Culture. Phytotherapy Research 26, 1075-1081.  http://dx.doi.org/10.1002/ptr.3699

Eisenhauer EL, Salani R and Copeland LJ (2012) Chapter 11 - Epithelial Ovarian Cancer. In ‘Clinical Gynecologic Oncology (Eighth Edition)’ (Ed.^(Eds  pp. 285-328. (Mosby: Philadelphia). http://www.sciencedirect.com/science/article/pii/B9780323074193000114

Fred Wong WS (2012) Introduction. Clinical and Experimental Pharmacology and Physiology 39, 253-255.  http://dx.doi.org/10.1111/j.1440-1681.2012.05682.x

Friedmann DR, Aguilar A, Fan J, Nachury MV and Marmorstein R (2012) Structure of the {alpha}-tubulin acetyltransferase, {alpha}TAT1, and implications for tubulin-specific acetylation. PNAS 109, 19655-19660.  http://www.pnas.org/cgi/content/abstract/109/48/19655

Galata M and Mahmoud S (2012) Chapter 5 - Bioactive Plant Isoprenoids: Biosynthetic and Biotechnological Approaches. In ‘Studies in Natural Products Chemistry’ (Ed.^(Eds Atta ur R) pp. 135-171. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444595140000055

Gouvea DR, Gobbo-Neto L and Lopes NP (2012) The Influence of Biotic and Abiotic Factors on the Production of Secondary Metabolites in Medicinal Plants. In ‘Plant Bioactives and Drug Discovery’ (Ed.^(Eds  pp. 419-452. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118260005.ch12

Gray AN, Spies TA and Pabst RJ (2012) Canopy gaps affect long-term patterns of tree growth and mortality in mature and old-growth forests in the Pacific Northwest. Forest Ecology and Management 281, 111-120.  http://www.sciencedirect.com/science/article/pii/S0378112712003647

Green S, Brasier CM, Schlenzig A, McCracken A, MacAskill GA, Wilson M and Webber JF (2012) The destructive invasive pathogen Phytophthora lateralis found on Chamaecyparis lawsoniana across the UK. Forest Pathology, n/a-n/a.  http://dx.doi.org/10.1111/j.1439-0329.2012.00788.x

Grobosch T, Schwarze B, Stoecklein D and Binscheck T (2012) Fatal poisoning with Taxus baccata. Quantification of Paclitaxel (taxol A), 10-Deacetyltaxol, Baccatin III, 10-Deacetylbaccatin III, Cephalomannine (taxol B), and 3,5-Dimethoxyphenol in Body Fluids by Liquid Chromatography-Tandem Mass Spectrometry. J Anal Toxicol 36, 36-43.  http://jat.oxfordjournals.org/cgi/content/abstract/36/1/36

Gruwez R, Leroux O, De Frenne P, Tack W, Viane R and Verheyen K (2012) Critical phases in the seed development of common juniper (Juniperus communis). Plant Biology, no-no.  http://dx.doi.org/10.1111/j.1438-8677.2012.00628.x

Gunatilaka AL (2012) Plant Natural Products. In ‘Natural Products in Chemical Biology’ (Ed.^(Eds  pp. 1-29. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch1

Hackenberg S, Scherzed A, Harnisch W, Froelich K, Ginzkey C, Koehler C, Hagen R and Kleinsasser N (2012) Antitumor activity of photo-stimulated zinc oxide nanoparticles combined with paclitaxel or cisplatin in HNSCC cell lines. Journal of Photochemistry and Photobiology B: Biology 114, 87-93.  http://www.sciencedirect.com/science/article/pii/S1011134412001091

Ham Y-M, Yoon W-J, Park S-Y, Jung Y-H, Kim D, Jeon Y-J, Wijesinghe WAJP, Kang S-M and Kim K-N (2012) Investigation of the component of Lycopodium serratum extract that inhibits proliferation and mediates apoptosis of human HL-60 leukemia cells. Food and Chemical Toxicology 50, 2629-2634.  http://www.sciencedirect.com/science/article/pii/S0278691512003626

Hamann A and Aitken SN (2012) Conservation planning under climate change: accounting for adaptive potential and migration capacity in species distribution models. Diversity and Distributions, n/a-n/a.  http://dx.doi.org/10.1111/j.1472-4642.2012.00945.x

Hao D-C, Xiao P-G, Ge G-B and Liu M (2012) Biological, Chemical, and Omics Research of Taxus Medicinal Resources. Drug Development Research 73, 477-486.  http://dx.doi.org/10.1002/ddr.21040

Hartley RM, Peng J, Fest GA, Dakshanamurthy S, Frantz DE, Brown ML and Mooberry SL (2012) Polygamain, a New Microtubule Depolymerizing Agent That Occupies a Unique Pharmacophore in the Colchicine Site. Mol. Pharmacol. 81, 431-439.  http://molpharm.aspetjournals.org/cgi/content/abstract/81/3/431

Hazalin NAMN, Ramasamy K, Lim SM, Cole ALJ and Majeed ABA (2012) Induction of apoptosis against cancer cell lines by four ascomycetes (endophytes) from Malaysian rainforest. Phytomedicine 19, 609-617.  http://www.sciencedirect.com/science/article/pii/S0944711312000396

Heck T, Geueke B and Kohler H-PE (2012) Bacterial β-Aminopeptidases: Structural Insights and Applications for Biocatalysis. Chemistry & Biodiversity 9, 2388-2409.  http://dx.doi.org/10.1002/cbdv.201200305

Hendrawati O, Woerdenbag HJ, Hille J and Kayser O (2012) Metabolic Engineering of Medicinal Plants and Microorganisms for the Production of Natural Products. In ‘Pharmaceutical Biotechnology’ (Ed.^(Eds  pp. 491-526. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527632909.ch19

Hendrikx JJMA, Lagas JS, Rosing H, Schellens JHM, Beijnen JH and Schinkel AH (2012) P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel. International Journal of Cancer, n/a-n/a.  http://dx.doi.org/10.1002/ijc.27912

Honda H, Nagai Y, et al. (2012) Glycyrrhizin and isoliquiritigenin suppress the LPS sensor Toll-like receptor 4/MD-2 complex signaling in a different manner. J. Leukoc. Biol. 91, 967-976.  http://www.jleukbio.org/cgi/content/abstract/91/6/967

Hu Q, Li W, Hu X, Hu Q, Shen J, Jin X, Zhou J, Tang G and Chu PK (2012) Synergistic treatment of ovarian cancer by co-delivery of survivin shRNA and paclitaxel via supramolecular micellar assembly. Biomaterials 33, 6580-6591.  http://www.sciencedirect.com/science/article/pii/S014296121200614X

Inamdar SR, Savanur MA, et al. (2012) The TF-antigen binding lectin from Sclerotium rolfsii inhibits growth of human colon cancer cells by inducing apoptosis in vitro and suppresses tumor growth in vivo. Glycobiology 22, 1227-1235.  http://glycob.oxfordjournals.org/cgi/content/abstract/22/9/1227

Jensen KH, Liesche J, Bohr T and Schulz A (2012) Universality of phloem transport in seed plants. Plant, Cell & Environment 35, 1065-1076.  http://dx.doi.org/10.1111/j.1365-3040.2011.02472.x

Jiang M, Stephanopoulos G and Pfeifer B (2012) Downstream reactions and engineering in the microbially reconstituted pathway for Taxol. Appl Microbiol Biotechnol 94, 841-9.

Jiang M, Stephanopoulos G and Pfeifer BA (2012) Toward Biosynthetic Design and Implementation of Escherichia coli-Derived Paclitaxel and Other Heterologous Polyisoprene Compounds. Appl. Envir. Microbiol. 78, 2497-2504.  http://aem.asm.org/cgi/content/abstract/78/8/2497

Kajani AA, Moghim S and Mofid MR (2012) Enhanced taxane production and secretion from Taxus baccata cell culture by adding dimethylsulfoxide. Biotechnology and Applied Biochemistry 59, 223-227.  http://dx.doi.org/10.1002/bab.1017

Keeling CI and Bohlmann J (2012) Plant Terpenoids. In ‘Natural Products in Chemical Biology’ (Ed.^(Eds  pp. 127-142. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch5

Kelber O, Steinhoff B and Kraft K (2012) Assessment of genotoxicity of herbal medicinal products: A co-ordinated approach. Phytomedicine 19, 472-476.  http://www.sciencedirect.com/science/article/pii/S0944711311005332

Khan W, Farah S and Domb AJ (2012) Drug eluting stents: Developments and current status. Journal of Controlled Release 161, 703-712.  http://www.sciencedirect.com/science/article/pii/S0168365912000879

Kim M-S, Stewart JE, Dumroese RK and Klopfenstein NB (2012) Occurrence of the Root Rot Pathogen, Fusarium commune, in Forest Nurseries of?the Midwestern and Western United States. Journal of Phytopathology 160, 112-114.  http://dx.doi.org/10.1111/j.1439-0434.2011.01865.x

Kingston DGI and Newman DJ (2012) Natural Products as Anticancer Agents. In ‘Natural Products in Chemical Biology’ (Ed.^(Eds  pp. 325-349. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch13

Kirschning A and Hahn F (2012) Vereinigung von chemischer Synthese und Biosynthese: ein neues Kapitel in der Totalsynthese von Naturstoffen und Naturstoffbibliotheken. Angewandte Chemie 124, 4086-4096.  http://dx.doi.org/10.1002/ange.201107386

Kirschning A and Hahn F (2012) Merging Chemical Synthesis and Biosynthesis: A New Chapter in the Total Synthesis of Natural Products and Natural Product Libraries. Angewandte Chemie International Edition 51, 4012-4022.  http://dx.doi.org/10.1002/anie.201107386

Koskinen AMP (2012) Alkaloids. In ‘Asymmetric Synthesis of Natural Products’ (Ed.^(Eds  pp. 257-287. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118347300.ch10

Koskinen AMP (2012) Index. In ‘Asymmetric Synthesis of Natural Products’ (Ed.^(Eds  pp. 289-306. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118347300.index

Kraitzer A, Alperstein D, Kloog Y and Zilberman M (2012) Mechanisms of antiproliferative drug release from bioresorbable porous structures. Journal of Biomedical Materials Research Part A, n/a-n/a.  http://dx.doi.org/10.1002/jbm.a.34436

Lange BM and Ahkami A (2012) Metabolic engineering of plant monoterpenes, sesquiterpenes and diterpenes—current status and future opportunities. Plant Biotechnology Journal, n/a-n/a.  http://dx.doi.org/10.1111/pbi.12022

Leandro-Garcia LJ, Leskela S, et al. (2012) Regulatory Polymorphisms in {beta}-Tubulin IIa Are Associated with Paclitaxel-Induced Peripheral Neuropathy. Clin. Cancer Res. 18, 4441-4448.  http://clincancerres.aacrjournals.org/cgi/content/abstract/18/16/4441

Lee K-H, Itokawa H, Akiyama T and Morris-Natschke SL (2012) Plant-Derived Natural Products Research in Drug Discovery. In ‘Natural Products in Chemical Biology’ (Ed.^(Eds  pp. 351-388. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch14

Lee W-L, Shiau J-Y and Shyur L-F (2012) Chapter 4 - Taxol, Camptothecin and Beyond for Cancer Therapy. In ‘Advances in Botanical Research’ (Ed.^(Eds Lie-Fen S and Allan SYL) pp. 133-178. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123945914000088

Lee W-L and Shyur L-F (2012) Deoxyelephantopin impedes mammary adenocarcinoma cell motility by inhibiting calpain-mediated adhesion dynamics and inducing reactive oxygen species and aggresome formation. Free Radical Biology and Medicine 52, 1423-1436.  http://www.sciencedirect.com/science/article/pii/S0891584912000640

Levy SM (2012) Section 7 - Lumber—Calculations to Select Framing and Trim Materials. In ‘Construction Calculations Manual’ (Ed.^(Eds  pp. 351-440. (Butterworth-Heinemann: Boston). http://www.sciencedirect.com/science/article/pii/B9780123822437000115

Li G, Kollner TG, Yin Y, Jiang Y, Chen H, Xu Y, Gershenzon J, Pichersky E and Chen F (2012) Nonseed plant Selaginella moellendorffii has both seed plant and microbial types of terpene synthases. PNAS 109, 14711-14715.  http://www.pnas.org/cgi/content/abstract/109/36/14711

Li L, Kim JK, Huh KM, Lee Y-k and Kim SY (2012) Targeted delivery of paclitaxel using folate-conjugated heparin-poly(β-benzyl-l-aspartate) self-assembled nanoparticles. Carbohydrate Polymers 87, 2120-2128.  http://www.sciencedirect.com/science/article/pii/S0144861711009362

Li S, Zhang P, Zhang M, Fu C and Yu L (2012) Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biology, no-no.  http://dx.doi.org/10.1111/j.1438-8677.2012.00611.x

Liang L, Lin S-W, Dai W, Lu J-K, Yang T-Y, Xiang Y, Zhang Y, Li R-T and Zhang Q (2012) Novel cathepsin B-sensitive paclitaxel conjugate: Higher water solubility, better efficacy and lower toxicity. Journal of Controlled Release 160, 618-629.  http://www.sciencedirect.com/science/article/pii/S0168365912001459

Lim J and Simanek EE (2012) Triazine dendrimers as drug delivery systems: From synthesis to therapy. Advanced Drug Delivery Reviews 64, 826-835.  http://www.sciencedirect.com/science/article/pii/S0169409X12001044

Loh XJ, Yee BJH and Chia FS (2012) Sustained delivery of paclitaxel using thermogelling poly(PEG/PPG/PCL urethane)s for enhanced toxicity against cancer cells. Journal of Biomedical Materials Research Part A, n/a-n/a.  http://dx.doi.org/10.1002/jbm.a.34198

Lohr M, Schwender J and Polle JEW (2012) Isoprenoid biosynthesis in eukaryotic phototrophs: A spotlight on algae. Plant Science 185–186, 9-22.  http://www.sciencedirect.com/science/article/pii/S0168945211002202

Lu F, Shen Y-Y, Shen Y-Q, Hou J-W, Wang Z-M and Guo S-R (2012) Treatments of paclitaxel with poly(vinyl pyrrolidone) to improve drug release from poly(ɛ-caprolactone) matrix for film-based stent. International Journal of Pharmaceutics 434, 161-168.  http://www.sciencedirect.com/science/article/pii/S0378517312005431

Lv Y, Song Q, Shao Q, Gao W, Mao H, Lou H, Qu X and Li X (2012) Comparison of the effects of marchantin C and fucoidan on sFlt-1 and angiogenesis in glioma microenvironment. Journal of Pharmacy and Pharmacology 64, 604-609.  http://dx.doi.org/10.1111/j.2042-7158.2011.01430.x

Manosroi J, Sainakham M, Manosroi W and Manosroi A (2012) Anti-proliferative and apoptosis induction activities of extracts from Thai medicinal plant recipes selected from MANOSROI II database. Journal of Ethnopharmacology 141, 451-459.  http://www.sciencedirect.com/science/article/pii/S0378874112001584

McPartland TJ, Patil RA, Malone MF and Roberts SC (2012) Liquid–liquid extraction for recovery of paclitaxel from plant cell culture: Solvent evaluation and use of extractants for partitioning and selectivity. Biotechnology Progress, n/a-n/a.  http://dx.doi.org/10.1002/btpr.1562

Messier MS, Shatford JPA and Hibbs DE (2012) Fire exclusion effects on riparian forest dynamics in southwestern Oregon. Forest Ecology and Management 264, 60-71.  http://www.sciencedirect.com/science/article/pii/S0378112711006050

Mirjalili MH, Farzaneh M, Bonfill M, Rezadoost H and Ghassempour A (2012) Isolation and characterization of Stemphylium sedicola SBU-16 as a new endophytic taxol-producing fungus from Taxus baccata grown in Iran. FEMS Microbiology Letters 328, 122-129.  http://dx.doi.org/10.1111/j.1574-6968.2011.02488.x

Mo M, Erdelyi I, Szigeti-Buck K, Benbow JH and Ehrlich BE (2012) Prevention of paclitaxel-induced peripheral neuropathy by lithium pretreatment. FASEB J 26, 4696-4709.  http://www.fasebj.org/cgi/content/abstract/26/11/4696

MOSBY TT, COSGROVE M, SARKARDEI S, PLATT KL and KAINA B (2012) Nutrition in Adult and Childhood Cancer: Role of Carcinogens and Anti-carcinogens. Anticancer Res 32, 4171-4192.  http://ar.iiarjournals.org/cgi/content/abstract/32/10/4171

Muńoz Solano D, Hoyos P, Hernáiz MJ, Alcántara AR and Sánchez-Montero JM (2012) Industrial biotransformations in the synthesis of building blocks leading to enantiopure drugs. Bioresource Technology 115, 196-207.  http://www.sciencedirect.com/science/article/pii/S0960852411017421

Naciri Y, Caetano S and Salamin N (2012) Plant DNA barcodes and the influence of gene flow. Molecular Ecology Resources 12, 575-580.  http://dx.doi.org/10.1111/j.1755-0998.2012.03130.x

Naill MC, Kolewe ME and Roberts SC (2012) Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochemical Engineering Journal 63, 50-56.  http://www.sciencedirect.com/science/article/pii/S1369703X12000125

Nicolaou KC, Hale CRH and Nilewski C (2012) A total synthesis trilogy: Calicheamicin γ1I, Taxol®, and brevetoxin A. The Chemical Record, n/a-n/a.  http://dx.doi.org/10.1002/tcr.201200005

Oh H-J, Jang HR, Jung KY and Kim J-H (2012) Evaluation of adsorbents for separation and purification of paclitaxel from plant cell cultures. Process Biochemistry 47, 331-334.  http://www.sciencedirect.com/science/article/pii/S1359511311004016

Park JH, Park JH, Hur HJ, Woo JS and Lee HJ (2012) Effects of silymarin and formulation on the oral bioavailability of paclitaxel in rats. European Journal of Pharmaceutical Sciences 45, 296-301.  http://www.sciencedirect.com/science/article/pii/S0928098711004283

Park SH, Kim ND, Jung J-K, Lee C-K, Han S-B and Kim Y (2012) Myeloid differentiation 2 as a therapeutic target of inflammatory disorders. Pharmacology &amp; Therapeutics 133, 291-298.  http://www.sciencedirect.com/science/article/pii/S0163725811002038

Polavarapu PL (2012) Determination of the Structures of Chiral Natural Products Using Vibrational Circular Dichroism. In ‘Comprehensive Chiroptical Spectroscopy’ (Ed.^(Eds  pp. 387-420. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118120392.ch11

Postma TJ and Heimans JJ (2012) Chapter 60 - Neurological complications of chemotherapy to the peripheral nervous system. In ‘Handbook of Clinical Neurology’ (Ed.^(Eds Wolfgang G and Riccardo S) pp. 917-936. (Elsevier). http://www.sciencedirect.com/science/article/pii/B978044453502300032X

Pourmohammadi N, Alimoradi H, Mehr SE, Hassanzadeh G, Hadian MR, Sharifzadeh M, Bakhtiarian A and Dehpour AR (2012) Lithium Attenuates Peripheral Neuropathy Induced by Paclitaxel in Rats. Basic & Clinical Pharmacology & Toxicology 110, 231-237.  http://dx.doi.org/10.1111/j.1742-7843.2011.00795.x

Prado S, Li Y and Nay B (2012) Chapter 8 - Diversity and Ecological Significance of Fungal Endophyte Natural Products. In ‘Studies in Natural Products Chemistry’ (Ed.^(Eds Atta ur R) pp. 249-296. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444538369000256

Prasad KR and Gutala P (2012) Total synthesis of (+)-phomopsolide B. Tetrahedron 68, 7489-7493.  http://www.sciencedirect.com/science/article/pii/S0040402012008824

Qi J, Zhao J and Kingston DGI (2012) Recent Progress in the Chemistry and Biology of Paclitaxel (TaxolTM) and Related Taxanes. In ‘Plant Bioactives and Drug Discovery’ (Ed.^(Eds  pp. 263-336. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118260005.ch8

Rathee P, Rathee D, Rathee D and Rathee S (2012) In-vitro cytotoxic activity of β-Sitosterol triacontenate isolated from Capparis decidua (Forsk.) Edgew. Asian Pacific Journal of Tropical Medicine 5, 225-230.  http://www.sciencedirect.com/science/article/pii/S1995764512600297

Rodriguez G, Fernandez-Gutierrez M, Parra J, Lopez-Bravo A, Molina M, Duocastella L and San Roman J (2012) Bioactive coatings for coronary stents: Modulation of cell proliferation by controlled release of anti-proliferative drugs. Journal of Bioactive and Compatible Polymers 27, 550-564.  http://jbc.sagepub.com/cgi/content/abstract/27/6/550

Rodríguez J, Castańeda G, Contento AM and Muńoz L (2012) Direct and fast determination of paclitaxel, morphine and codeine in urine by micellar electrokinetic chromatography. Journal of Chromatography A 1231, 66-72.  http://www.sciencedirect.com/science/article/pii/S0021967312002312

Rukachaisirikul V, Rodglin A, Phongpaichit S, Buatong J and Sakayaroj J (2012) α-Pyrone and seiricuprolide derivatives from the mangrove-derived fungi Pestalotiopsis spp. PSU-MA92 and PSU-MA119. Phytochemistry Letters 5, 13-17.  http://www.sciencedirect.com/science/article/pii/S1874390011001078

Sarpietro MG, Ottimo S, Paolino D, Ferrero A, Dosio F and Castelli F (2012) Squalenoyl prodrug of paclitaxel: Synthesis and evaluation of its incorporation in phospholipid bilayers. International Journal of Pharmaceutics 436, 135-140.  http://www.sciencedirect.com/science/article/pii/S0378517312006321

Siddiqui MS, Thodey K, Trenchard I and Smolke CD (2012) Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools. FEMS Yeast Research 12, 144-170.  http://dx.doi.org/10.1111/j.1567-1364.2011.00774.x

Sim HA, Lee J-Y and Kim J-H (2012) Evaluation of a high surface area acetone/pentane precipitation process for the purification of paclitaxel from plant cell cultures. Separation and Purification Technology 89, 112-116.  http://www.sciencedirect.com/science/article/pii/S1383586612000421

Singh SB (2012) Pharmaceuticals: Natural Products and Natural Product Models. In ‘Natural Products in Chemical Biology’ (Ed.^(Eds  pp. 287-324. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch12

Skrzypczak-Pietraszek E and Pietraszek J (2012) Chemical profile and seasonal variation of phenolic acid content in bastard balm (Melittis melissophyllum L., Lamiaceae). Journal of Pharmaceutical and Biomedical Analysis 66, 154-161.  http://www.sciencedirect.com/science/article/pii/S0731708512001604

Taylor P, Arsenak M, et al. (2012) Screening of Venezuelan medicinal plant extracts for cytostatic and cytotoxic activity against tumor cell lines. Phytotherapy Research, n/a-n/a.  http://dx.doi.org/10.1002/ptr.4752

Thiel P, Kaiser M and Ottmann C (2012) Niedermolekulare Stabilisatoren von Protein-Protein-Wechselwirkungen: ein unterschätztes Konzept in der Wirkstoffentwicklung? Angewandte Chemie 124, 2052-2059.  http://dx.doi.org/10.1002/ange.201107616

Thiel P, Kaiser M and Ottmann C (2012) Small-Molecule Stabilization of Protein–Protein Interactions: An Underestimated Concept in Drug Discovery? Angewandte Chemie International Edition 51, 2012-2018.  http://dx.doi.org/10.1002/anie.201107616

Towne DL, Nicholl EE, Comess KM, Galasinski SC, Hajduk PJ and Abraham VC (2012) Development of a High-Content Screening Assay Panel to Accelerate Mechanism of Action Studies for Oncology Research. J Biomol Screen 17, 1005-1017.  http://jbx.sagepub.com/cgi/content/abstract/17/8/1005

Valentijn JA, van Driel LF, Jansen KA, Valentijn KM and Koster AJ (2012) Toward A 3D View of Cellular Architecture: Correlative Light Microscopy and Electron Tomography. In ‘Biomedical Imaging’ (Ed.^(Eds  pp. 180-214. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118271933.ch6

Varlet V and Augsburger M (2012) Monitoring of aglycons of yew glycosides (3,5-dimethoxyphenol, myrtenol and 1-octen-3-ol) as first indicator of yew presence. Drug Testing and Analysis, n/a-n/a.  http://dx.doi.org/10.1002/dta.391

Vasantha Kumar S, Srinath S and Saha RN (2012) A Simple and Rapid 3D View Method for Selective and Sensitive Determination of Paclitaxel in Micro Volume Rat Plasma by LC-Diode Array UV and Its Application to a Pharmacokinetic Study. J Chromatogr Sci 50, 259-270.  http://chromsci.oxfordjournals.org/cgi/content/abstract/50/3/259

Vella-zarb L, Baisch U and Dinnebier RE (2012) Small molecule, big difference: The role of water in the crystallization of paclitaxel. Journal of Pharmaceutical Sciences, n/a-n/a.  http://dx.doi.org/10.1002/jps.23404

Vennila R, Kamalraj S and Muthumary J (2012) In vitro studies on anticancer activity of fungal taxol against human breast cancer cell line MCF-7 cells. Biomedicine &amp; Aging Pathology 2, 16-18.  http://www.sciencedirect.com/science/article/pii/S2210522012000020

Vergara D, Bellomo C, et al. (2012) Lapatinib/Paclitaxel polyelectrolyte nanocapsules for overcoming multidrug resistance in ovarian cancer. Nanomedicine: Nanotechnology, Biology and Medicine 8, 891-899.  http://www.sciencedirect.com/science/article/pii/S1549963411005223

Vieira JM and Riley PR (2012) Chemical genetics and its potential in cardiac stem cell therapy. British Journal of Pharmacology, no-no.  http://dx.doi.org/10.1111/j.1476-5381.2012.01928.x

von Euler H, Rivera P, Nyman H, Häggström J and BorgŠO (2012) A dose-finding study with a novel water-soluble formulation of paclitaxel for the treatment of malignant high-grade solid tumours in dogs. Veterinary and Comparative Oncology, n/a-n/a.  http://dx.doi.org/10.1111/j.1476-5829.2011.00314.x

Wakabayashi K, Mintz GS, et al. (2012) Impact of Drug-Eluting Stents on Distal Vessels. Circ Cardiovasc Interv 5, 211-219.  http://circinterventions.ahajournals.org/cgi/content/abstract/5/2/211

Wen C-C, Chen H-M and Yang N-S (2012) Chapter 6 - Developing Phytocompounds from Medicinal Plants as Immunomodulators. In ‘Advances in Botanical Research’ (Ed.^(Eds Lie-Fen S and Allan SYL) pp. 197-272. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123945914000040

Wender PA, Galliher WC, Bhat NM, Pillow TH, Bieber MM and Teng NNH (2012) Taxol-oligoarginine conjugates overcome drug resistance in-vitro in human ovarian carcinoma. Gynecologic Oncology 126, 118-123.  http://www.sciencedirect.com/science/article/pii/S0090825812002508

Wilson CR and Hooser SB (2012) Chapter 82 - Toxicity of yew (Taxus spp.) alkaloids. In ‘Veterinary Toxicology (Second Edition)’ (Ed.^(Eds  pp. 1121-1127. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780123859266001101

Wilson SA and Roberts SC (2012) Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules. Plant Biotechnology Journal 10, 249-268.  http://dx.doi.org/10.1111/j.1467-7652.2011.00664.x

Wittmann A and Süß B (2012) RNA-Schalter. Biologie in unserer Zeit 42, 159-164.  http://dx.doi.org/10.1002/biuz.201210477

Woo CC, Kumar AP, Sethi G and Tan KHB (2012) Thymoquinone: Potential cure for inflammatory disorders and cancer. Biochemical Pharmacology 83, 443-451.  http://www.sciencedirect.com/science/article/pii/S0006295211007350

Xiao Y, Liu Y and Wang G (2012) Involvement of nitric oxide in the mechanism of biochemical alterations induced by simulated microgravity in Microcystis aeruginosa. Advances in Space Research 49, 850-858.  http://www.sciencedirect.com/science/article/pii/S0273117711007629

Xu B, Ding J, Chen K-X, Miao Z-H, Huang H, Liu H and Luo X-M (2012) 12 - Advances in Cancer Chemotherapeutic Drug Research in China. In ‘Recent Advances in Cancer Research and Therapy’ (Ed.^(Eds  pp. 287-350. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780123978332000121

Xu J, Ma L, Liu Y, Xu F, Nie J and Ma G (2012) Design and characterization of antitumor drug paclitaxel-loaded chitosan nanoparticles by W/O emulsions. International Journal of Biological Macromolecules 50, 438-443.  http://www.sciencedirect.com/science/article/pii/S0141813011004958

Xu Q, Liu Y, Su S, Li W, Chen C and Wu Y (2012) Anti-tumor activity of paclitaxel through dual-targeting carrier of cyclic RGD and transferrin conjugated hyperbranched copolymer nanoparticles. Biomaterials 33, 1627-1639.  http://www.sciencedirect.com/science/article/pii/S0142961211013500

YANG J-S, LIU C-W, et al. (2012) Chlorogenic Acid Induces Apoptotic Cell Death in U937 Leukemia Cells through Caspase- and Mitochondria-dependent Pathways. In Vivo 26, 971-978.  http://iv.iiarjournals.org/cgi/content/abstract/26/6/971

Yang L-Q, Wang B, et al. (2012) Enhanced oral bioavailability and anti-tumour effect of paclitaxel by 20(s)-ginsenoside Rg3 in vivo. Biopharmaceutics & Drug Disposition 33, 425-436.  http://dx.doi.org/10.1002/bdd.1806

Yang W-X, Zhao Z-G, Wang L-H, Yu S-J and Liang Z-S (2012) Control of hypertension in rats using volatile components of leaves of Taxus chinensis var. mairei. Journal of Ethnopharmacology 141, 309-313.  http://www.sciencedirect.com/science/article/pii/S0378874112001213

Yao Y, Zhang B, Chen H, Chen N, Liu L, Yishan W, Li C and Zheng Q (2012) Alteronol inhibits proliferation in HeLa cells through inducing a G1-phase arrest. Journal of Pharmacy and Pharmacology 64, 101-107.  http://dx.doi.org/10.1111/j.2042-7158.2011.01375.x

YE L, JI K, FREWER N, JI J and JIANG WG (2012) Impact of Yangzheng Xiaoji on the Adhesion and Migration of Human Cancer Cells: the Role of the AKT Signalling Pathway. Anticancer Res 32, 2537-2543.  http://ar.iiarjournals.org/cgi/content/abstract/32/7/2537

Ye VM and Bhatia SK (2012) Metabolic engineering for the production of clinically important molecules: Omega-3 fatty acids, artemisinin, and taxol. Biotechnology Journal 7, 20-33.  http://dx.doi.org/10.1002/biot.201100289

Yeung ED, Morrison A, Plumeri D, Wang J, Tong C, Yan X and Li J (2012) Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway. The Prostate 72, 165-172.  http://dx.doi.org/10.1002/pros.21417

You P, Qiu J, Su E and Wei D (2012) Carica papaya Lipase Catalysed Resolution of β-Amino Esters for the Highly Enantioselective Synthesis of (S)-Dapoxetine. European Journal of Organic Chemistry, n/a-n/a.  http://dx.doi.org/10.1002/ejoc.201201055

Yu J, Wang Y, Qian H, Zhao Y, Liu B and Fu C (2012) Polyprenols from the needles of Taxus chinensis var. mairei. Fitoterapia 83, 831-837.  http://www.sciencedirect.com/science/article/pii/S0367326X12000342

Yuan D-m, Lv Y-l, et al. (2012) Efficacy and safety of Abraxane in treatment of progressive and recurrent non- small cell lung cancer patients: a retrospective clinical study. Thoracic Cancer, no-no.  http://dx.doi.org/10.1111/j.1759-7714.2012.00113.x

Zabaleta V, Ponchel G, Salman H, Agüeros M, Vauthier C and Irache JM (2012) Oral administration of paclitaxel with pegylated poly(anhydride) nanoparticles: Permeability and pharmacokinetic study. European Journal of Pharmaceutics and Biopharmaceutics 81, 514-523.  http://www.sciencedirect.com/science/article/pii/S0939641112000975

Zacharaki P, Stephanou G and Demopoulos NA (2012) Comparison of the aneugenic properties of nocodazole, paclitaxel and griseofulvin in vitro. Centrosome defects and alterations in protein expression profiles. Journal of Applied Toxicology, n/a-n/a.  http://dx.doi.org/10.1002/jat.2745

Zerbe P, Chiang A and Bohlmann J (2012) Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism. Phytochemistry 74, 30-39.  http://www.sciencedirect.com/science/article/pii/S0031942211004900

Zerbe P, Chiang A and Bohlmann J (2012) Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism. Phytochemistry 74, 30-9.

Zerbe P, Chiang A, Yuen M, Hamberger B, Hamberger B, Draper JA, Britton R and Bohlmann J (2012) Bifunctional cis-Abienol Synthase from Abies balsamea Discovered by Transcriptome Sequencing and Its Implications for Diterpenoid Fragrance Production. J. Biol. Chem. 287, 12121-12131.  http://www.jbc.org/cgi/content/abstract/287/15/12121

Zhang K, Li Y, et al. (2012) New 6/8/6-Taxanes Isolated from the Heartwood of Taxus cuspidata. Helvetica Chimica Acta 95, 1566-1572.  http://dx.doi.org/10.1002/hlca.201200045

Zhao H, Li Y, Zhang X, Korpelainen H and Li C (2012) Sex-related and stage-dependent source-to-sink transition in Populus cathayana grown at elevated CO2 and elevated temperature. Tree Physiol 32, 1325-1338.  http://treephys.oxfordjournals.org/cgi/content/abstract/32/11/1325

Zhao P and Astruc D (2012) Docetaxel Nanotechnology in Anticancer Therapy. ChemMedChem 7, 952-972.  http://dx.doi.org/10.1002/cmdc.201200052

Zhao Y, Li J, Yu H, Wang G and Liu W (2012) Synthesis and characterization of a novel polydepsipeptide contained tri-block copolymer (mPEG–PLLA–PMMD) as self-assembly micelle delivery system for paclitaxel. International Journal of Pharmaceutics 430, 282-291.  http://www.sciencedirect.com/science/article/pii/S0378517312002840

Zhou K, Gao Y, Hoy JA, Mann FM, Honzatko RB and Peters RJ (2012) Insights into Diterpene Cyclization from Structure of Bifunctional Abietadiene Synthase from Abies grandis. J. Biol. Chem. 287, 6840-6850.  http://www.jbc.org/cgi/content/abstract/287/9/6840

Zonneveld BJM (2012) Conifer genome sizes of 172 species, covering 64 of 67 genera, range from 8 to 72 picogram. Nordic Journal of Botany, no-no.  http://dx.doi.org/10.1111/j.1756-1051.2012.01516.x

(2011) Index. In ‘Traditional Herbal Medicine Research Methods’ (Ed.^(Eds  pp. 457-466. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470921340.index

Al Marzouqi N, Iratni R, et al. (2011) Frondoside A inhibits human breast cancer cell survival, migration, invasion and the growth of breast tumor xenografts. European Journal of Pharmacology 668, 25-34.  http://www.sciencedirect.com/science/article/pii/S0014299911007308

Alcántara AR, Hernaiz MJ and Sinisterra JV (2011) 3.28 - Biocatalyzed Production of Fine Chemicals. In ‘Comprehensive Biotechnology (Second Edition)’ (Ed.^(Eds Editor-in-Chief:  Murray M-Y) pp. 309-331. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780080885049002257

Alonso-Castro AJ, Villarreal ML, Salazar-Olivo LA, Gomez-Sanchez M, Dominguez F and Garcia-Carranca A (2011) Mexican medicinal plants used for cancer treatment: Pharmacological, phytochemical and ethnobotanical studies. Journal of Ethnopharmacology 133, 945-972.  http://www.sciencedirect.com/science/article/pii/S0378874110008408

Amos LA (2011) What tubulin drugs tell us about microtubule structure and dynamics. Seminars in Cell &amp; Developmental Biology 22, 916-926.  http://www.sciencedirect.com/science/article/pii/S1084952111001704

Aydemir EA, Oz ES, Göktürk RS, Ozkan G and Fiskin K (2011) Glycyrrhiza flavescens subsp. antalyensis exerts antiproliferative effects on melanoma cells via altering TNF-α and IFN-α levels. Food and Chemical Toxicology 49, 820-828.  http://www.sciencedirect.com/science/article/pii/S0278691510007088

Braam S and Passier R (2011) Chapter 11 - Stem Cells for Discovery of Effective and Safe New Drugs. In ‘STEM CELLS’ (Ed.^(Eds  pp. 257-274. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780123815354100115

Buchwald-Werner S and Bischoff F (2011) Natural Products–Market Development and Potentials. In ‘Industrial Scale Natural Products Extraction’ (Ed.^(Eds  pp. 247-267. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527635122.ch8

Butler A and Keating R (2011) Old herbal remedies and modern combination therapy. Scottish Medical Journal 56, 170-173.  http://scm.sagepub.com/cgi/content/abstract/56/3/170

Chen D, Pan X, Xiao P, Farwell MA and Zhang B (2011) Evaluation and identification of reliable reference genes for pharmacogenomics, toxicogenomics, and small RNA expression analysis. Journal of Cellular Physiology 226, 2469-2477.  http://dx.doi.org/10.1002/jcp.22725

Chen J, Lu L, feng Y, Wang H, Dai L, li Y and Zhang P (2011) PKD2 mediates multi-drug resistance in breast cancer cells through modulation of P-glycoprotein expression. Cancer Letters 300, 48-56.  http://www.sciencedirect.com/science/article/pii/S0304383510004283

Chen Y, Yang C and Wang ZJ (2011) Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain. Neuroscience 193, 440-451.  http://www.sciencedirect.com/science/article/pii/S0306452211008062

Costa R, Motta EM, Dutra RC, Manjavachi MN, Bento AF, Malinsky FR, Pesquero JB and Calixto JB (2011) Anti-nociceptive effect of kinin B1 and B2 receptor antagonists on peripheral neuropathy induced by paclitaxel in mice. British Journal of Pharmacology 164, 681-693.  http://dx.doi.org/10.1111/j.1476-5381.2011.01408.x

Das B and Damodar K (2011) Epoxides and Oxetanes. In ‘Heterocycles in Natural Product Synthesis’ (Ed.^(Eds  pp. 63-95. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527634880.ch3

Demain AL and Vaishnav P (2011) Natural products for cancer chemotherapy. Microbial Biotechnology 4, 687-699.  http://dx.doi.org/10.1111/j.1751-7915.2010.00221.x

Dhillon RS, Hooda MS, Pundeer JS, Ahlawat KS and Chopra I (2011) Effects of auxins and thiamine on the efficacy of techniques of clonal propagation in Jatropha curcas L. Biomass and Bioenergy 35, 1502-1510.  http://www.sciencedirect.com/science/article/pii/S096195341000471X

Dietrich JA, Fortman JL, Juminaga D and Keasling JD (2011) Microbial Production of Plant-Derived Pharmaceutical Natural Products through Metabolic Engineering: Artemisinin and beyond. In ‘Biocatalysis for Green Chemistry and Chemical Process Development’ (Ed.^(Eds  pp. 173-196. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118028308.ch7

Favoni RE and Florio T (2011) Combined chemotherapy with cytotoxic and targeted compounds for the management of human malignant pleural mesothelioma. Trends in Pharmacological Sciences 32, 463-479.  http://www.sciencedirect.com/science/article/pii/S0165614711000654

Garg S, Magro M and Serruys PW (2011) 6.627 - Drug-Eluting Stents. In ‘Comprehensive Biomaterials’ (Ed.^(Eds Editor-in-Chief:  Paul D) pp. 427-448. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780080552941002324

Gebauer R, Volarik D, Urban J, Borja I, Nagy NE, Eldhuset TD and Krokene P (2011) Effect of thinning on anatomical adaptations of Norway spruce needles. Tree Physiol 31, 1103-1113.  http://treephys.oxfordjournals.org/cgi/content/abstract/31/10/1103

Gordon M and Apple C (2011) Field monitoring the seasonal variation in Albatrellus ellisii mycelium abundance with a species-specific genetic marker. Mycologia 103, 950-958.  http://www.mycologia.org/cgi/content/abstract/103/5/950

Guo H, Wu H, et al. (2011) Synthesis, characterization and biological evaluation of some 16E-arylidene androstane derivatives as potential anticancer agents. Steroids 76, 709-723.  http://www.sciencedirect.com/science/article/pii/S0039128X11001139

Guo J, Gao X, et al. (2011) Aptamer-functionalized PEG–PLGA nanoparticles for enhanced anti-glioma drug delivery. Biomaterials 32, 8010-8020.  http://www.sciencedirect.com/science/article/pii/S0142961211007757

Gupta A and Middleton M (2011) Chapter 45 - Cytostatic and cytotoxic drugs. In ‘Side Effects of Drugs Annual’ (Ed.^(Eds Aronson JK) pp. 935-962. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444537416000453

Hait WN (2011) Forty Years of Translational Cancer Research. Cancer Discovery 1, 383-390.  http://cancerdiscovery.aacrjournals.org/cgi/content/abstract/1/5/383

Heldt H-W and Piechulla B (2011) 16 - Secondary metabolites fulfill specific ecological functions in plants. In ‘Plant Biochemistry (Fourth Edition)’ (Ed.^(Eds  pp. 399-408. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780123849861000168

Hendrikx JJMA, Hillebrand MJX, Thijssen B, Rosing H, Schinkel AH, Schellens JHM and Beijnen JH (2011) A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry. Journal of Chromatography B 879, 2984-2990.  http://www.sciencedirect.com/science/article/pii/S1570023211005605

Hillwig ML, Xu M, Toyomasu T, Tiernan MS, Wei G, Cui G, Huang L and Peters RJ (2011) Domain loss has independently occurred multiple times in plant terpene synthase evolution. The Plant Journal 68, 1051-1060.  http://dx.doi.org/10.1111/j.1365-313X.2011.04756.x

Hor SY, Ahmad M, Farsi E, Lim CP, Asmawi MZ and Yam MF (2011) Acute and subchronic oral toxicity of Coriolus versicolor standardized water extract in Sprague-Dawley rats. Journal of Ethnopharmacology 137, 1067-1076.  http://www.sciencedirect.com/science/article/pii/S037887411100482X

Hsu H-F, Huang K-H, Lu K-J, Chiou S-J, Yen J-H, Chang C-C and Houng J-Y (2011) Typhonium blumei extract inhibits proliferation of human lung adenocarcinoma A549 cells via induction of cell cycle arrest and apoptosis. Journal of Ethnopharmacology 135, 492-500.  http://www.sciencedirect.com/science/article/pii/S0378874111001991

Hwang J-H, Takagi M, Murakami H, Sekido Y and Shin-ya K (2011) Induction of tubulin polymerization and apoptosis in malignant mesothelioma cells by a new compound JBIR-23. Cancer Letters 300, 189-196.  http://www.sciencedirect.com/science/article/pii/S0304383510004817

Iqbal J, Sarti F, Perera G and Bernkop-Schnürch A (2011) Development and in vivo evaluation of an oral drug delivery system for paclitaxel. Biomaterials 32, 170-175.  http://www.sciencedirect.com/science/article/pii/S0142961210011919

Jaggi AS, Jain V and Singh N (2011) Animal models of neuropathic pain. Fundamental & Clinical Pharmacology 25, 1-28.  http://dx.doi.org/10.1111/j.1472-8206.2009.00801.x

Jiang X, Xin H, et al. (2011) PEGylated poly(trimethylene carbonate) nanoparticles loaded with paclitaxel for the treatment of advanced glioma: In vitro and in vivo evaluation. International Journal of Pharmaceutics 420, 385-394.  http://www.sciencedirect.com/science/article/pii/S0378517311008234

Jiao Z, Chen Z, Wu Y and Ma S (2011) Determination of Paclitaxel Solubility in Carbon Dioxide Using Quartz Crystal Microbalance. Chinese Journal of Chemical Engineering 19, 227-231.  http://www.sciencedirect.com/science/article/pii/S1004954111601596

Jung D-W, Kim J, et al. (2011) A Triazine Compound S06 Inhibits Proinvasive Crosstalk between Carcinoma Cells and Stromal Fibroblasts via Binding to Heat Shock Protein 90. Chemistry &amp; Biology 18, 1581-1590.  http://www.sciencedirect.com/science/article/pii/S1074552111003607

Keeling CI, Madilao LL, Zerbe P, Dullat HK and Bohlmann J (2011) The Primary Diterpene Synthase Products of Picea abies Levopimaradiene/Abietadiene Synthase (PaLAS) Are Epimers of a Thermally Unstable Diterpenol. J. Biol. Chem. 286, 21145-21153.  http://www.jbc.org/cgi/content/abstract/286/24/21145

Kenth S, Sylvestre J-P, Fuhrmann K, Meunier M and Leroux J-C (2011) Fabrication of paclitaxel nanocrystals by femtosecond laser ablation and fragmentation. Journal of Pharmaceutical Sciences 100, 1022-1030.  http://dx.doi.org/10.1002/jps.22335

Kim S-K, Thomas NV and Li X (2011) Chapter 16 - Anticancer Compounds from Marine Macroalgae and Their Application as Medicinal Foods. In ‘Advances in Food and Nutrition Research’ (Ed.^(Eds Se-Kwon K) pp. 213-224. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123876690000168

Kirtane AJ, Caixeta A, Généreux P, Patel R and Moses JW (2011) Sirolimus and Paclitaxel Eluting Stent Clinical Studies. In ‘Interventional Cardiology’ (Ed.^(Eds  pp. 502-518. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781444319446.ch34

Koetsier MJ, Jekel PA, Wijma HJ, Bovenberg RAL and Janssen DB (2011) Aminoacyl-coenzyme A synthesis catalyzed by a CoA ligase from Penicillium chrysogenum. FEBS Letters 585, 893-898.  http://www.sciencedirect.com/science/article/pii/S0014579311001190

Koksal M, Jin Y, Coates R, Croteau R and Christianson D (2011) Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis. Nature 469, 116-20.

Kraitzer A, Kloog Y, Haklai R and Zilberman M (2011) Composite fiber structures with antiproliferative agents exhibit advantageous drug delivery and cell growth inhibition in vitro. Journal of Pharmaceutical Sciences 100, 133-149.  http://dx.doi.org/10.1002/jps.22238

Kurdziel KA, Kalen JD, et al. (2011) Human Dosimetry and Preliminary Tumor Distribution of 18F-Fluoropaclitaxel in Healthy Volunteers and Newly Diagnosed Breast Cancer Patients Using PET/CT. J. Nucl. Med. 52, 1339-1345.  http://jnm.snmjournals.org/cgi/content/abstract/52/9/1339

Leclercq G, de Cremoux P, This P and Jacquot Y (2011) Lack of sufficient information on the specificity and selectivity of commercial phytoestrogens preparations for therapeutic purposes. Maturitas 68, 56-64.  http://www.sciencedirect.com/science/article/pii/S0378512210003816

Lee J-Y and Kim J-H (2011) Development and optimization of a novel simultaneous microwave-assisted extraction and adsorbent treatment process for separation and recovery of paclitaxel from plant cell cultures. Separation and Purification Technology 80, 240-245.  http://www.sciencedirect.com/science/article/pii/S1383586611002590

Lee Y-H, Lee Y-R, et al. (2011) Baccatin III, a synthetic precursor of taxol, enhances MHC-restricted antigen presentation in dendritic cells. International Immunopharmacology 11, 985-991.  http://www.sciencedirect.com/science/article/pii/S1567576911001044

Licciardi PV and Underwood JR (2011) Plant-derived medicines: A novel class of immunological adjuvants. International Immunopharmacology 11, 390-398.  http://www.sciencedirect.com/science/article/pii/S1567576910003437

Liu H-W (2011) Extraction and Isolation of Compounds from Herbal Medicines. In ‘Traditional Herbal Medicine Research Methods’ (Ed.^(Eds  pp. 81-138. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470921340.ch3

Liu N, Zheng Y, Zhu Y, Xiong S and Chu Y (2011) Selective Impairment of CD4&#xa0;+&#xa0;CD25&#xa0;+&#xa0;Foxp3&#xa0;+&#xa0;Regulatory T cells by paclitaxel is explained by Bcl-2/Bax mediated apoptosis. International Immunopharmacology 11, 212-219.  http://www.sciencedirect.com/science/article/pii/S1567576910003851

Liu S-C, Ye X, Guo L-D and Liu L (2011) Cytotoxic Isoprenylated Epoxycyclohexanediols from the Plant Endophyte Pestalotiopsis fici. Chinese Journal of Natural Medicines 9, 374-379.  http://www.sciencedirect.com/science/article/pii/S1875536411600794

Liu WJH (2011) Introduction to Traditional Herbal Medicines and their Study. In ‘Traditional Herbal Medicine Research Methods’ (Ed.^(Eds  pp. 1-26. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470921340.ch1

Lu H-F, Xie C, Chang J, Lin G-Q and Sun X (2011) Synthesis, cytotoxicity, metabolic stability and pharmacokinetic evaluation of fluorinated docetaxel analogs. European Journal of Medicinal Chemistry 46, 1743-1748.  http://www.sciencedirect.com/science/article/pii/S0223523411001383

Lu K-W, Chen J-C, et al. (2011) Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2 -9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways. Human and Experimental Toxicology 30, 406-415.  http://het.sagepub.com/cgi/content/abstract/30/5/406

Lubbe A and Verpoorte R (2011) Cultivation of medicinal and aromatic plants for specialty industrial materials. Industrial Crops and Products 34, 785-801.  http://www.sciencedirect.com/science/article/pii/S0926669011000380

Ma C, Jiang D and Wei X (2011) Mutation breeding of Emericella foeniculicola TR21 for improved production of tanshinone IIA. Process Biochemistry 46, 2059-2063.  http://www.sciencedirect.com/science/article/pii/S1359511311002522

Malik S, Cusidó RM, Mirjalili MH, Moyano E, Palazón J and Bonfill M (2011) Production of the anticancer drug taxol in Taxus baccata suspension cultures: A review. Process Biochemistry 46, 23-34.  http://www.sciencedirect.com/science/article/pii/S1359511310003442

Marinelli F and Marcone GL (2011) 3.26 - Microbial Secondary Metabolites. In ‘Comprehensive Biotechnology (Second Edition)’ (Ed.^(Eds Editor-in-Chief:  Murray M-Y) pp. 285-297. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780080885049005390

Marx SO, Totary-Jain H and Marks AR (2011) Vascular Smooth Muscle Cell Proliferation in Restenosis. Circ Cardiovasc Interv 4, 104-111.  http://circinterventions.ahajournals.org

Mayor S (2011) Tree that provides paclitaxel is put on list of endangered species. BMJ 343, d7411-.  http://www.bmj.com

McAndrew Ryan P, Peralta-Yahya Pamela P, DeGiovanni A, Pereira Jose H, Hadi Masood Z, Keasling Jay D and Adams Paul D (2011) Structure of a Three-Domain Sesquiterpene Synthase: A Prospective Target for Advanced Biofuels Production. Structure 19, 1876-1884.  http://www.sciencedirect.com/science/article/pii/S096921261100325X

Misawa N (2011) Pathway engineering for functional isoprenoids. Current Opinion in Biotechnology 22, 627-633.  http://www.sciencedirect.com/science/article/pii/S0958166911000164

Mishra BB and Tiwari VK (2011) Natural products: An evolving role in future drug discovery. European Journal of Medicinal Chemistry 46, 4769-4807.  http://www.sciencedirect.com/science/article/pii/S0223523411005708

Mo R, Jin X, Li N, Ju C, Sun M, Zhang C and Ping Q (2011) The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles. Biomaterials 32, 4609-4620.  http://www.sciencedirect.com/science/article/pii/S0142961211002456

Monks NR, Li B, Gunjan S, Rogers DT, Kulshrestha M, Falcone DL and Littleton JM (2011) Natural Products Genomics: A novel approach for the discovery of anti-cancer therapeutics. Journal of Pharmacological and Toxicological Methods 64, 217-225.  http://www.sciencedirect.com/science/article/pii/S1056871911002371

Nanda R, Sasmal A and Nayak PL (2011) Preparation and characterization of chitosan–polylactide composites blended with Cloisite 30B for control release of the anticancer drug paclitaxel. Carbohydrate Polymers 83, 988-994.  http://www.sciencedirect.com/science/article/pii/S0144861710007381

Ng WK, Yazan LS and Ismail M (2011) Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein. Toxicology in Vitro 25, 1392-1398.  http://www.sciencedirect.com/science/article/pii/S0887233311001366

Núńez Sellés AJ (2011) Natural Health Products (NHPs). In ‘Encyclopedia of Environmental Health’ (Ed.^(Eds Editor-in-Chief:  Jerome ON) pp. 33-43. (Elsevier: Burlington). http://www.sciencedirect.com/science/article/pii/B9780444522726004864

Nussbaumer S, Bonnabry P, Veuthey J-L and Fleury-Souverain S (2011) Analysis of anticancer drugs: A review. Talanta 85, 2265-2289.  http://www.sciencedirect.com/science/article/pii/S0039914011007533

Ohmann JL, Gregory MJ, Henderson EB and Roberts HM (2011) Mapping gradients of community composition with nearest-neighbour imputation: extending plot data for landscape analysis. Journal of Vegetation Science 22, 660-676.  http://dx.doi.org/10.1111/j.1654-1103.2010.01244.x

Onrubia M, Moyano E, Bonfill M, Palazón J, Goossens A and Cusidó RM (2011) The relationship between TXS, DBAT, BAPT and DBTNBT gene expression and taxane production during the development of Taxus baccata plantlets. Plant Science 181, 282-287.  http://www.sciencedirect.com/science/article/pii/S0168945211001695

Pandi M, Rajapriya P, Suresh G, Ravichandran N, Manikandan R, Thiagarajan R and Muthumary J (2011) A fungal taxol from Botryodiplodia theobromae Pat., attenuates 7, 12 dimethyl benz(a)anthracene (DMBA)-induced biochemical changes during mammary gland carcinogenesis. Biomedicine &amp; Preventive Nutrition 1, 95-102.  http://www.sciencedirect.com/science/article/pii/S2210523911000249

Park J-H, Yan Y-D, Chi S-C, Hwang DH, Shanmugam S, Lyoo WS, Woo JS, Yong CS and Choi H-G (2011) Preparation and evaluation of Cremophor-free paclitaxel solid dispersion by a supercritical antisolvent process. Journal of Pharmacy and Pharmacology 63, 491-499.  http://dx.doi.org/10.1111/j.2042-7158.2010.01218.x

Park SB, Lin CSY, Krishnan AV, Friedlander ML, Lewis CR and Kiernan MC (2011) Early, progressive, and sustained dysfunction of sensory axons underlies paclitaxel-induced neuropathy. Muscle & Nerve 43, 367-374.  http://dx.doi.org/10.1002/mus.21874

Paterson I, Naylor GJ, Gardner NM, Guzmán E and Wright AE (2011) Total Synthesis and Biological Evaluation of a Series of Macrocyclic Hybrids and Analogues of the Antimitotic Natural Products Dictyostatin, Discodermolide, and Taxol. Chemistry – An Asian Journal 6, 459-473.  http://dx.doi.org/10.1002/asia.201000541

Pignata S, Cannella L, Leopardo D, Pisano C, Bruni GS and Facchini G (2011) Chemotherapy in epithelial ovarian cancer. Cancer Letters 303, 73-83.  http://www.sciencedirect.com/science/article/pii/S0304383511000528

Podolski-Renić A, Anđelković T, Banković J, Tanić N, Ruždijić S and Pešić M (2011) The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines. Biomedicine &amp; Pharmacotherapy 65, 345-353.  http://www.sciencedirect.com/science/article/pii/S0753332211000540

Procházková D and Wilhelmová Na (2011) Nitric oxide, reactive nitrogen species and associated enzymes during plant senescence. Nitric Oxide 24, 61-65.  http://www.sciencedirect.com/science/article/pii/S1089860311000061

Pyo S-H and Choi H-J (2011) An improved high-performance liquid chromatography process for the large-scale production of paclitaxel. Separation and Purification Technology 76, 378-384.  http://www.sciencedirect.com/science/article/pii/S1383586610004569

Quintyne KI, Mainstone P, McNamara B, Boers P, Wallis F and Gupta RK (2011) Profound and persistent painful paclitaxel peripheral neuropathy in a premenopausal patient. BMJ Case Reports 2011, bcr1220103645-.  http://casereports.bmj.com/cgi/content/abstract/2011/may08_1/bcr1220103645

Räber L and Windecker S (2011) Current Status of Drug-Eluting Stents. Cardiovascular Therapeutics 29, 176-189.  http://dx.doi.org/10.1111/j.1755-5922.2010.00144.x

Randall JA and Walters MB (2011) Deer density effects on vegetation in aspen forest understories over site productivity and stand age gradients. Forest Ecology and Management 261, 408-415.  http://www.sciencedirect.com/science/article/pii/S0378112710006389

Rimoldi I, Pellizzoni M, Facchetti G, Molinari F, Zerla D and Gandolfi R (2011) Chemo- and biocatalytic strategies to obtain phenylisoserine, a lateral chain of Taxol by asymmetric reduction. Tetrahedron: Asymmetry 22, 2110-2116.  http://www.sciencedirect.com/science/article/pii/S0957416611006434

Robin C, Piou D, Feau N, Douzon G, Schenck N and Hansen EM (2011) Root and aerial infections of Chamaecyparis lawsoniana by Phytophthora lateralis: a new threat for European countries. Forest Pathology 41, 417-424.  http://dx.doi.org/10.1111/j.1439-0329.2010.00688.x

Root HT and Nelson PR (2011) Does phylogenetic distance aid in detecting environmental gradients related to species composition? Journal of Vegetation Science 22, 1143-1148.  http://dx.doi.org/10.1111/j.1654-1103.2011.01320.x

Sahoo N, Manchikanti P and Dey SH (2011) Herbal drug patenting in India: IP potential. Journal of Ethnopharmacology 137, 289-297.  http://www.sciencedirect.com/science/article/pii/S0378874111003758

Sanchez S and Demain AL (2011) 1.12 - Secondary Metabolites. In ‘Comprehensive Biotechnology (Second Edition)’ (Ed.^(Eds Editor-in-Chief:  Murray M-Y) pp. 155-167. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780080885049000180

Sarr DA, Hibbs DE, Shatford JPA and Momsen R (2011) Influences of life history, environmental gradients, and disturbance on riparian tree regeneration in Western Oregon. Forest Ecology and Management 261, 1241-1253.  http://www.sciencedirect.com/science/article/pii/S0378112711000041

Sartor O, Michels RM, Massard C and de Bono JS (2011) Novel Therapeutic Strategies for Metastatic Prostate Cancer in the Post-Docetaxel Setting. Oncologist 16, 1487-1497.  http://theoncologist.alphamedpress.org/cgi/content/abstract/16/11/1487

Sasikala V, Saravanan S and Parimelazhagan T (2011) Analgesic and anti–inflammatory activities of Passiflora foetida L. Asian Pacific Journal of Tropical Medicine 4, 600-603.  http://www.sciencedirect.com/science/article/pii/S1995764511601557

Schäfer B (2011) Taxol®. Hoffnung gegen Krebs. Chemie in unserer Zeit 45, 32-46.  http://dx.doi.org/10.1002/ciuz.201100539

Seitz J and Ojima I (2011) Drug Conjugates with Polyunsaturated Fatty Acids. In ‘Drug Delivery in Oncology’ (Ed.^(Eds  pp. 1323-1357. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527634057.ch41

Shen H, Lee FY and Gan J (2011) Ixabepilone, a Novel Microtubule-Targeting Agent for Breast Cancer, Is a Substrate for P-Glycoprotein (P-gp/MDR1/ABCB1) but not Breast Cancer Resistance Protein (BCRP/ABCG2). J. Pharmacol. Exp. Ther. 337, 423-432.  http://jpet.aspetjournals.org/cgi/content/abstract/337/2/423

Soca-Chafre G, Rivera-Orduńa FN, Hidalgo-Lara ME, Hernandez-Rodriguez C, Marsch R and Flores-Cotera LB (2011) Molecular phylogeny and paclitaxel screening of fungal endophytes from Taxus globosa. Fungal Biology 115, 143-156.  http://www.sciencedirect.com/science/article/pii/S1878614610001856

Stanton RA, Gernert KM, Nettles JH and Aneja R (2011) Drugs that target dynamic microtubules: A new molecular perspective. Medicinal Research Reviews 31, 443-481.  http://dx.doi.org/10.1002/med.20242

Strobel G, Singh SK, Riyaz-Ul-Hassan S, Mitchell AM, Geary B and Sears J (2011) An endophytic/pathogenic Phoma sp. from creosote bush producing biologically active volatile compounds having fuel potential. FEMS Microbiology Letters 320, 87-94.  http://dx.doi.org/10.1111/j.1574-6968.2011.02297.x

Sugai Y, Ueno Y, Hayashi K-i, Oogami S, Toyomasu T, Matsumoto S, Natsume M, Nozaki H and Kawaide H (2011) Enzymatic 13C Labeling and Multidimensional NMR Analysis of Miltiradiene Synthesized by Bifunctional Diterpene Cyclase in Selaginella moellendorffii. J. Biol. Chem. 286, 42840-42847.  http://www.jbc.org/cgi/content/abstract/286/50/42840

Sumner LW, Yang DS, Bench BJ, Watson BS, Li C and Jones AD (2011) Spatially Resolved Plant Metabolomics. In ‘Annual Plant Reviews Volume 43’ (Ed.^(Eds  pp. 343-366. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781444339956.ch11

Szucs I, Escobar M and Grodzinski B (2011) 4.21 - Emerging Roles for Plant Terpenoids. In ‘Comprehensive Biotechnology (Second Edition)’ (Ed.^(Eds Editor-in-Chief:  Murray M-Y) pp. 273-286. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780080885049002695

Tanaka K, Li F, Morikawa K, Nobukawa T and Kadota S (2011) Analysis of biosynthetic fluctuations of cultured Taxus seedlings using a metabolomic approach. Phytochemistry 72, 1760-1766.  http://www.sciencedirect.com/science/article/pii/S0031942211002822

Vaishnav P and Demain AL (2011) Unexpected applications of secondary metabolites. Biotechnology Advances 29, 223-229.  http://www.sciencedirect.com/science/article/pii/S0734975010001564

Valladares-Narganes LM, Sánchez-Sambucety P and Rodríguez-Prieto MÁ (2011) Cambios ungueales por taxoles. A propósito de un caso. Piel 26, 422-423.  http://www.sciencedirect.com/science/article/pii/S0213925111002930

Vemula PK, Campbell NR, Zhao F, Xu B, John G and Karp JM (2011) 4.421 - Self-Assembled Prodrugs. In ‘Comprehensive Biomaterials’ (Ed.^(Eds Editor-in-Chief:  Paul D) pp. 339-355. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780080552941001355

Vennila R and Muthumary J (2011) Taxol from Pestalotiopsis pauciseta VM1, an endophytic fungus of Tabebuia pentaphylla. Biomedicine &amp; Preventive Nutrition 1, 103-108.  http://www.sciencedirect.com/science/article/pii/S2210523911000250

Wang H, Zhao Y, Wu Y, Hu Y-l, Nan K, Nie G and Chen H (2011) Enhanced anti-tumor efficacy by co-delivery of doxorubicin and paclitaxel with amphiphilic methoxy PEG-PLGA copolymer nanoparticles. Biomaterials 32, 8281-8290.  http://www.sciencedirect.com/science/article/pii/S0142961211008039

Wang J and Lu W (2011) Chiral Drugs via Biocatalytical Approaches. In ‘Chiral Drugs’ (Ed.^(Eds  pp. 77-136. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118075647.ch3

Wang K, Wang T, Li J, Zou J, Chen Y and Dai J (2011) Microbial hydrolysis of 7-xylosyl-10-deacetyltaxol to 10-deacetyltaxol. Journal of Molecular Catalysis B: Enzymatic 68, 250-255.  http://www.sciencedirect.com/science/article/pii/S1381117710002961

Wang Y, Li X, Wang L, Xu Y, Cheng X and Wei P (2011) Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery. Int J Nanomedicine 6, 1497-507.

Watchueng J, Kamnaing P, Gao J-M, Kiyota T, Yeboah F and Konishi Y (2011) Efficient purification of paclitaxel from yews using high-performance displacement chromatography technique. Journal of Chromatography A 1218, 2929-2935.  http://www.sciencedirect.com/science/article/pii/S0021967311003451

White JG (2011) CHAPTER 32 - Disorders affecting megakaryocytes and platelets: Inherited conditions. In ‘Blood and Bone Marrow Pathology (Second Edition)’ (Ed.^(Eds  pp. 491-521. (Churchill Livingstone: Edinburgh). http://www.sciencedirect.com/science/article/pii/B9780702031472000328

Wimalasekera R, Tebartz F and Scherer GFE (2011) Polyamines, polyamine oxidases and nitric oxide in development, abiotic and biotic stresses. Plant Science 181, 593-603.  http://www.sciencedirect.com/science/article/pii/S0168945211001014

Xue C, Zhao H, liu H, Chen Y, Wang B, Zhang Q and Wu X (2011) Development of sulfhydrylated antibody functionalized microcantilever immunosensor for taxol. Sensors and Actuators B: Chemical 156, 863-866.  http://www.sciencedirect.com/science/article/pii/S0925400511001778

Yang C, Wang J-S and Kong L-Y (2011) Chemical Constituents from the Needles of Taxus canadensis. Chinese Journal of Natural Medicines 9, 188-190.  http://www.sciencedirect.com/science/article/pii/S1875536411600320

Yao H-J, Ju R-J, Wang X-X, Zhang Y, Li R-J, Yu Y, Zhang L and Lu W-L (2011) The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery. Biomaterials 32, 3285-3302.  http://www.sciencedirect.com/science/article/pii/S0142961211000512

Yoder A, Guo J, Yu D, Cui Z, Zhang X-E and Wu Y (2011) Effects of Microtubule Modulators on HIV-1 Infection of Transformed and Resting CD4 T Cells. J. Virol. 85, 3020-3024.  http://jvi.asm.org/cgi/content/abstract/85/6/3020

Yuan H, Yang G-p and Huang Z-j (2011) Clinical Study of Traditional Herbal Medicine. In ‘Traditional Herbal Medicine Research Methods’ (Ed.^(Eds  pp. 343-375. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470921340.ch8

Yue GGL, Fan J-T, Lee JKM, Zeng G-Z, Ho TWF, Fung K-P, Leung P-C, Tan N-H and Lau CBS (2011) Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells. British Journal of Pharmacology 164, 1883-1898.  http://dx.doi.org/10.1111/j.1476-5381.2011.01458.x

Yue Z-G, Wei W, You Z-X, Yang Q-Z, Yue H, Su Z-G and Ma G-H (2011) Iron Oxide Nanotubes for Magnetically Guided Delivery and pH-Activated Release of Insoluble Anticancer Drugs. Advanced Functional Materials 21, 3446-3453.  http://dx.doi.org/10.1002/adfm.201100510

Zhao Y, Zhang H-B, Liu J-K, Su J, Li Y, Yao Z-J and Zhao Q-S (2011) Fragmentations of 13-oxo-taxyunnansin A and their application to preparation of abeo-paclitaxel and abeo-docetaxel analogues. Tetrahedron Letters 52, 139-142.  http://www.sciencedirect.com/science/article/pii/S0040403910019957

Zheng C-J, Sun P-X, Jin G-L and Qin L-P (2011) Sesquiterpenoids from Trichoderma atroviride, an endophytic fungus in Cephalotaxus fortunei. Fitoterapia 82, 1035-1038.  http://www.sciencedirect.com/science/article/pii/S0367326X11001663

Zheng Y, Shen L, Yu M, Fan B, Zhao D, Liu L and Sheng J (2011) Nitric oxide synthase as a postharvest response in pathogen resistance of tomato fruit. Postharvest Biology and Technology 60, 38-46.  http://www.sciencedirect.com/science/article/pii/S092552141000267X

Zheng Y-B, Chen D-X, Li J-J and Huang J-Z (2011) New Sesquiterpenoid from Pestalotiopsis sp. Chinese Journal of Natural Medicines 9, 421-424.  http://www.sciencedirect.com/science/article/pii/S1875536411600861

Zhong JJ (2011) 3.27 - Plant Secondary Metabolites. In ‘Comprehensive Biotechnology (Second Edition)’ (Ed.^(Eds Editor-in-Chief:  Murray M-Y) pp. 299-308. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780080885049001902

Zhu Y, Liu N, Xiong SD, Zheng YJ and Chu YW (2011) CD4+Foxp3+ Regulatory T-cell Impairment by Paclitaxel is Independent of Toll-like Receptor 4. Scandinavian Journal of Immunology 73, 301-308.  http://dx.doi.org/10.1111/j.1365-3083.2011.02514.x

(2010) Index. In ‘Green Chemistry in the Pharmaceutical Industry’ (Ed.^(Eds  pp. 357-370. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527629688.index

Agüeros M, Zabaleta V, Espuelas S, Campanero MA and Irache JM (2010) Increased oral bioavailability of paclitaxel by its encapsulation through complex formation with cyclodextrins in poly(anhydride) nanoparticles. Journal of Controlled Release 145, 2-8.  http://www.sciencedirect.com/science/article/pii/S0168365910002178

Ajikumar PK, Xiao W-H, et al. (2010) Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli. Science 330, 70-74.  http://www.sciencemag.org/cgi/content/abstract/330/6000/70

Ando K, Hasegawa K, et al. (2010) Human lactoferrin activates NF-κB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling. FEBS Journal 277, 2051-2066.  http://dx.doi.org/10.1111/j.1742-4658.2010.07620.x

Arndt H-D, Hackenberger C and Schwarzer D (2010) Semisynthese. Chemie mit den Molekülen der Natur. Chemie in unserer Zeit 44, 130-137.  http://dx.doi.org/10.1002/ciuz.201000499

Bayindir ZS and Yuksel N (2010) Characterization of niosomes prepared with various nonionic surfactants for paclitaxel oral delivery. Journal of Pharmaceutical Sciences 99, 2049-2060.  http://dx.doi.org/10.1002/jps.21944

Bigelow JC and Gad SC (2010) Combinatorial Compounds and Drug Discovery. In ‘Pharmaceutical Sciences Encyclopedia’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470571224.pse432

Bjorkman AD and Vellend M (2010) Defining Historical Baselines for Conservation: Ecological Changes Since European Settlement on Vancouver Island, Canada

Definición de Líneas de Base Históricas para la Conservación: Cambios Ecológicos desde el Asentamiento Europeo en la Isla Vancouver, Canadá. Conservation Biology 24, 1559-1568.  http://dx.doi.org/10.1111/j.1523-1739.2010.01550.x

Brasier CM, Vettraino AM, Chang TT and Vannini A (2010) Phytophthora lateralis discovered in an old growth Chamaecyparis forest in Taiwan. Plant Pathology 59, 595-603.  http://dx.doi.org/10.1111/j.1365-3059.2010.02278.x

Breathnach SM (2010) Drug Reactions. In ‘Rook’s Textbook of Dermatology’ (Ed.^(Eds  pp. 1-177. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781444317633.ch75

Bull VH, Fargestad EM, Strozynski M and Thiede B (2010) Temporal proteome profiling of taxol-induced mitotic arrest and apoptosis. ELECTROPHORESIS 31, 1873-1885.  http://dx.doi.org/10.1002/elps.200900780

Burkhard JA, Wuitschik G, Rogers-Evans M, Müller K and Carreira EM (2010) Oxetane als vielseitige Bausteine in der Wirkstoff-Forschung und Synthese. Angewandte Chemie 122, 9236-9251.  http://dx.doi.org/10.1002/ange.200907155

Burkhard JA, Wuitschik G, Rogers-Evans M, Müller K and Carreira EM (2010) Oxetanes as Versatile Elements in Drug Discovery and Synthesis. Angewandte Chemie International Edition 49, 9052-9067.  http://dx.doi.org/10.1002/anie.200907155

Burns KC, Berg J, Bialynicka-Birula A, Kratchmer S and Shortt K (2010) Tree diversity on islands: assembly rules, passive sampling and the theory of island biogeography. Journal of Biogeography 37, 1876-1883.  http://dx.doi.org/10.1111/j.1365-2699.2010.02352.x

Cheng K-W, Wong C-C, Wang M, He Q-Y and Chen F (2010) Identification and characterization of molecular targets of natural products by mass spectrometry. Mass Spectrometry Reviews 29, 126-155.  http://dx.doi.org/10.1002/mas.20235

Colombaroli D and Gavin DG (2010) Highly episodic fire and erosion regime over the past 2,000 y in the Siskiyou Mountains, Oregon. PNAS 107, 18909-18914.  http://www.pnas.org/cgi/content/abstract/107/44/18909

Davey MR and Anthony P (2010) Index. In ‘Plant Cell Culture’ (Ed.^(Eds  pp. 333-341. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470686522.index

DeLong JM and Prange RK (2010) Taxus spp.: Botany, Horticulture, and Source of Anti-Cancer Compounds. In ‘Horticultural Reviews’ (Ed.^(Eds  pp. 299-327. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470767986.ch6

Delzon S, Douthe C, Sala A and Cochard H (2010) Mechanism of water-stress induced cavitation in conifers: bordered pit structure and function support the hypothesis of seal capillary-seeding. Plant, Cell & Environment 33, 2101-2111.  http://dx.doi.org/10.1111/j.1365-3040.2010.02208.x

Demain AL (2010) History of Industrial Biotechnology. In ‘Industrial Biotechnology’ (Ed.^(Eds  pp. 17-77. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527630233.ch1

DeMay BS, Meseroll RA, Occhipinti P and Gladfelter AS (2010) Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton. Cytoskeleton 67, 383-399.  http://dx.doi.org/10.1002/cm.20452

Desbiens SC, Farb DH and Gad SC (2010) Current Needs for New Therapeutic Agents and Discovery Strategies—A Systems Pharmacology Approach. In ‘Pharmaceutical Sciences Encyclopedia’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470571224.pse416

Desmarchelier C (2010) Neotropics and natural ingredients for pharmaceuticals: why isn’t South American biodiversity on the crest of the wave? Phytotherapy Research 24, 791-799.  http://dx.doi.org/10.1002/ptr.3114

Dovčiak M and Halpern CB (2010) Positive diversity–stability relationships in forest herb populations during four decades of community assembly. Ecology Letters 13, 1300-1309.  http://dx.doi.org/10.1111/j.1461-0248.2010.01524.x

Dubreuil M, Riba M, Gonzalez-Martinez SC, Vendramin GG, Sebastiani F and Mayol M (2010) Genetic effects of chronic habitat fragmentation revisited: Strong genetic structure in a temperate tree, Taxus baccata (Taxaceae), with great dispersal capability. Am. J. Botany 97, 303-310.  http://www.amjbot.org/cgi/content/abstract/97/2/303

Dudek AZ, Powell SF and Gad SC (2010) Oncology. In ‘Pharmaceutical Sciences Encyclopedia’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470571224.pse459

Exposito O, Syklowska-Baranek K, Moyano E, Onrubia M, Bonfill M, Palazon J and Cusido RM (2010) Metabolic responses of Taxus media transformed cell cultures to the addition of methyl jasmonate. Biotechnology Progress 26, 1145-1153.  http://dx.doi.org/10.1002/btpr.424

Eyles A, Bonello P, Ganley R and Mohammed C (2010) Induced resistance to pests and pathogens in trees. New Phytologist 185, 893-908.  http://dx.doi.org/10.1111/j.1469-8137.2009.03127.x

Falara V, Pichersky E and Kanellis AK (2010) A Copal-8-ol Diphosphate Synthase from the Angiosperm Cistus creticus subsp. creticus Is a Putative Key Enzyme for the Formation of Pharmacologically Active, Oxygen-Containing Labdane-Type Diterpenes. Plant Physiology 154, 301-310.  http://www.plantphysiol.org/cgi/content/abstract/154/1/301

Feng X, Sun L, Fu S, Zou Z and Sun D-A (2010) Microbial transformation of 7-epi-10-deacetylbaccatin III to 10-deacetylbaccatin III. Journal of Molecular Catalysis B: Enzymatic 64, 45-47.  http://www.sciencedirect.com/science/article/pii/S1381117710000408

Forró E and Fülöp F (2010) New Enzymatic Two-Step Cascade Reaction for the Preparation of a Key Intermediate for the Taxol Side-Chain. European Journal of Organic Chemistry 2010, 3074-3079.  http://dx.doi.org/10.1002/ejoc.201000262

Gao L, Geng Y, Li BO, Chen J and Yang JI (2010) Genome-wide DNA methylation alterations of Alternanthera philoxeroides in natural and manipulated habitats: implications for epigenetic regulation of rapid responses to environmental fluctuation and phenotypic variation. Plant, Cell & Environment 33, 1820-1827.  http://dx.doi.org/10.1111/j.1365-3040.2010.02186.x

González-Martínez SC, Dubreuil M, Riba M, Vendramin GG, Sebastiani F and Mayol M (2010) Spatial genetic structure of Taxus baccata L. in the western Mediterranean Basin: Past and present limits to gene movement over a broad geographic scale. Molecular Phylogenetics and Evolution 55, 805-815.  http://www.sciencedirect.com/science/article/pii/S1055790310000990

Guimarăes DO, Borges WS, et al. (2010) Diketopiperazines produced by endophytic fungi found in association with two Asteraceae species. Phytochemistry 71, 1423-1429.  http://www.sciencedirect.com/science/article/pii/S0031942210001871

Halpern CB, Antos JA, Rice JM, Haugo RD and Lang NL (2010) Tree invasion of a montane meadow complex: temporal trends, spatial patterns, and biotic interactions. Journal of Vegetation Science 21, 717-732.  http://dx.doi.org/10.1111/j.1654-1103.2010.01183.x

Han M-G, Jeon K-Y, Mun S and Kim J-H (2010) Development of a micelle-fractional precipitation hybrid process for the pre-purification of paclitaxel from plant cell cultures. Process Biochemistry 45, 1368-1374.  http://www.sciencedirect.com/science/article/pii/S1359511310001911

Heilmann J (2010) New Medical Applications of Plant Secondary Metabolites. In ‘Annual Plant Reviews Volume 39: Functions and Biotechnology of Plant Secondary Metabolites’ (Ed.^(Eds  pp. 348-380. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781444318876.ch5

Jacobs BL, Lee CT and Montie JE (2010) Bladder Cancer in 2010: How Far have We Come? CA: A Cancer Journal for Clinicians 60, 244-272.  http://dx.doi.org/10.3322/caac.20077

Jha V (2010) Herbal medicines and chronic kidney disease. Nephrology 15, 10-17.  http://dx.doi.org/10.1111/j.1440-1797.2010.01305.x

Kathiravan G and Sri Raman V (2010) In vitro TAXOL production, by Pestalotiopsis breviseta — A first report. Fitoterapia 81, 557-564.  http://www.sciencedirect.com/science/article/pii/S0367326X10000389

Kazandjieva J, Gergovska M, Darlenski R, Márina S, Broshtilova V, Balabanova M and Stransky L (2010) Recall dermatitis after systemic treatment with paclitaxel. International Journal of Dermatology 49, 956-959.  http://dx.doi.org/10.1111/j.1365-4632.2010.04499.x

Khanduri VP and Sharma CM (2010) Male and female reproductive phenology and annual production of male cones in two natural populations of Cedrus deodara. Nordic Journal of Botany 28, 119-127.  http://dx.doi.org/10.1111/j.1756-1051.2009.00335.x

Kim SY and Yun-Choi HS (2010) A comparative optical aggregometry study of antiplatelet activity of taxanes from Taxus cuspidata. Thrombosis Research 125, e281-e284.  http://www.sciencedirect.com/science/article/pii/S0049384810000988

Koudelka Š, Turánek-Knötigová P, MaŠek J, Korvasová Z, Škrabalová M, Plocková J, Bartheldyová E and Turánek J (2010) Liposomes with high encapsulation capacity for paclitaxel: Preparation, characterisation and in vivo anticancer effect. Journal of Pharmaceutical Sciences 99, 2309-2319.  http://dx.doi.org/10.1002/jps.21992

Kumar S, Mahdi H, Bryant C, Shah J, Garg G and Munkarah A (2010) Clinical trials and progress with paclitaxel in ovarian cancer. Int J Womens Health 2, 411-27.

Lee D-H, Kim S-G, Mun S and Kim J-H (2010) Evaluation of feeding and mixing conditions for fractional precipitation of paclitaxel from plant cell cultures. Process Biochemistry 45, 1134-1140.  http://www.sciencedirect.com/science/article/pii/S1359511310001340

Lim WT, Tan EH, Toh CK, Hee SW, Leong SS, Ang PCS, Wong NS and Chowbay B (2010) Phase I pharmacokinetic study of a weekly liposomal paclitaxel formulation (Genexol®-PM) in patients with solid tumors. Ann. Onc. 21, 382-388.  http://annonc.oxfordjournals.org/cgi/content/abstract/21/2/382

Liu T and Khosla C (2010) A Balancing Act for Taxol Precursor Pathways in E. coli. Science 330, 44-45.  http://www.sciencemag.org

MARLER L, CONDA-SHERIDAN M, CINELLI MA, MORRELL AE, CUSHMAN M, CHEN L, HUANG K, VAN BREEMEN R and PEZZUTO JM (2010) Cancer Chemopreventive Potential of Aromathecins and Phenazines, Novel Natural Product Derivatives. Anticancer Res 30, 4873-4882.  http://ar.iiarjournals.org/cgi/content/abstract/30/12/4873

Mountford PG (2010) The Taxol® Story – Development of a Green Synthesis via Plant Cell Fermentation. In ‘Green Chemistry in the Pharmaceutical Industry’ (Ed.^(Eds  pp. 145-160. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527629688.ch7

Nandurdikar RS, Subrahmanyam AV and Kaliappan KP (2010) Synthesis of a Novel Taxa-Oxa-Sugar Hybrid Core Structure by Tandem Cross-Enyne Metathesis/IMDA. European Journal of Organic Chemistry 2010, 2788-2799.  http://dx.doi.org/10.1002/ejoc.201000001

Narita N, Fujieda S, et al. (2010) Suppression of histone deacetylase 3 (HDAC3) enhances apoptosis induced by paclitaxel in human maxillary cancer cells in vitro and in vivo. Biochemical and Biophysical Research Communications 396, 310-316.  http://www.sciencedirect.com/science/article/pii/S0006291X10007692

Neil P (2010) The ecological importance of species and the Noah’s Ark problem. Ecological Economics 69, 478-485.  http://www.sciencedirect.com/science/article/pii/S092180090900408X

Ngo QA, Roussi F, Thoret S and Guéritte F (2010) Elaboration of Simplified Vinca Alkaloids and Phomopsin Hybrids. Chemical Biology & Drug Design 75, 284-294.  http://dx.doi.org/10.1111/j.1747-0285.2009.00922.x

Ofek P, Miller K, Eldar-Boock A, Polyak D, Segal E and Satchi-Fainaro R (2010) Rational Design of Multifunctional Polymer Therapeutics for Cancer Theranostics. Israel Journal of Chemistry 50, 185-203.  http://dx.doi.org/10.1002/ijch.201000020

Onrubia M, Moyano E, Bonfill M, Expósito O, Palazón J and Cusidó RM (2010) An approach to the molecular mechanism of methyl jasmonate and vanadyl sulphate elicitation in Taxus baccata cell cultures: The role of txs and bapt gene expression. Biochemical Engineering Journal 53, 104-111.  http://www.sciencedirect.com/science/article/pii/S1369703X10002640

Pan L, Chai H and Kinghorn AD (2010) The continuing search for antitumor agents from higher plants. Phytochemistry Letters 3, 1-8.  http://www.sciencedirect.com/science/article/pii/S1874390009001128

Pandi M, Manikandan R and Muthumary J (2010) Anticancer activity of fungal taxol derived from Botryodiplodia theobromae Pat., an endophytic fungus, against 7, 12 dimethyl benz(a)anthracene (DMBA)-induced mammary gland carcinogenesis in Sprague dawley rats. Biomedicine &amp; Pharmacotherapy 64, 48-53.  http://www.sciencedirect.com/science/article/pii/S075333220900047X

Pfannenstiel LW, Lam SSK, Emens LA, Jaffee EM and Armstrong TD (2010) Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice. Cellular Immunology 263, 79-87.  http://www.sciencedirect.com/science/article/pii/S0008874910000638

Qiang F, Lee B-J, Ha I, Kang KW, Woo E-R and Han H-K (2010) Effect of maceligan on the systemic exposure of paclitaxel: In vitro and in vivo evaluation. European Journal of Pharmaceutical Sciences 41, 226-231.  http://www.sciencedirect.com/science/article/pii/S0928098710002423

Risinger AL and Mooberry SL (2010) Taccalonolides: Novel microtubule stabilizers with clinical potential. Cancer Letters 291, 14-19.  http://www.sciencedirect.com/science/article/pii/S0304383509006193

Sheldon R (2010) Introduction to Green Chemistry, Organic Synthesis and Pharmaceuticals. In ‘Green Chemistry in the Pharmaceutical Industry’ (Ed.^(Eds  pp. 1-20. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527629688.ch1

Shukla S, Mehta A, Mehta P, Vyas SP, Shukla S and Bajpai VK (2010) Studies on anti-inflammatory, antipyretic and analgesic properties of Caesalpinia bonducella F. seed oil in experimental animal models. Food and Chemical Toxicology 48, 61-64.  http://www.sciencedirect.com/science/article/pii/S0278691509004232

Soberón JR, Sgariglia MA, Sampietro DA, Quiroga EN, Sierra MG and Vattuone MA (2010) Purification and identification of antibacterial phenolics from Tripodanthus acutifolius leaves. Journal of Applied Microbiology 108, 1757-1768.  http://dx.doi.org/10.1111/j.1365-2672.2009.04579.x

Sonaimuthu V, Krishnamoorthy S and Johnpaul M (2010) Optimization of process parameters for improved production of Taxol by a novel endophytic fungus Pestalotiopsis oxyanthi SVJM060isolated from Taxus baccta. Journal of Biotechnology 150, Supplement, 471.  http://www.sciencedirect.com/science/article/pii/S0168165610016111

Sonaimuthu V, Krishnamoorthy S and Johnpaul M (2010) Taxol producing endophytic fungus Fusarium culmorum SVJM072 from medicinal plant of Tinospora cordifolia - a first report. Journal of Biotechnology 150, Supplement, 425.  http://www.sciencedirect.com/science/article/pii/S0168165610014951

Spainhour CB and Gad SC (2010) Natural Products. In ‘Pharmaceutical Sciences Encyclopedia’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470571224.pse002

Stamelou M, de Silva R, Arias-Carrion O, Boura E, Hollerhage M, Oertel WH, Muller U and Hoglinger GU (2010) Rational therapeutic approaches to progressive supranuclear palsy. Brain 133, 1578-1590.  http://brain.oxfordjournals.org/cgi/content/abstract/133/6/1578

Tomback DF and Achuff P (2010) Blister rust and western forest biodiversity: ecology, values and outlook for white pines. Forest Pathology 40, 186-225.  http://dx.doi.org/10.1111/j.1439-0329.2010.00655.x

Wang X, Zheng H, Zhu Z, Wei Y and Chen L (2010) Clinical pharmacokinetics of paclitaxel liposome with a new route of administration in human based on the analysis with ultra performance liquid chromatography. Journal of Pharmaceutical Sciences 99, 4746-4752.  http://dx.doi.org/10.1002/jps.22169

Wani MA, Sanjana K, Kumar DM and Lal DK (2010) GC – MS analysis reveals production of 2 – Phenylethanol from Aspergillus niger endophytic in rose. Journal of Basic Microbiology 50, 110-114.  http://dx.doi.org/10.1002/jobm.200900295

Yousefzadi M, Sharifi M, Behmanesh M, Moyano E, Bonfill M, Cusido RM and Palazon J (2010) Podophyllotoxin: Current approaches to its biotechnological production and future challenges. Engineering in Life Sciences 10, 281-292.  http://dx.doi.org/10.1002/elsc.201000027

Yuan L, Wu L, Chen J, Wu Q and Hu S (2010) Paclitaxel acts as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice. Vaccine 28, 4402-4410.  http://www.sciencedirect.com/science/article/pii/S0264410X10005529

Zhang D, Zhang L, Wang D, Suo B and Shi X (2010) A PCR METHOD FOR THE DETECTION OF LISTERIA MONOCYTOGENES BASED ON A NOVEL TARGET SEQUENCE IDENTIFIED BY COMPARATIVE GENOMIC ANALYSIS. Journal of Food Safety 30, 832-847.  http://dx.doi.org/10.1111/j.1745-4565.2010.00245.x

Zuo K-Q, Zhang X-P, Zou J, Li D and Lv Z-W (2010) Establishment of a Paclitaxel Resistant Human Breast Cancer Cell Strain (MCF-7/Taxol) and Intracellular Paclitaxel Binding Protein Analysis. Journal of International Medical Research 38, 1428-1435.  http://imr.sagepub.com/cgi/content/abstract/38/4/1428

(2009) Index. In ‘Nitric Oxide in Plant Physiology’ (Ed.^(Eds  pp. 203-210. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527629138.index

(2009) Phytophthora lateralis. EPPO Bulletin 39, 43-47.  http://dx.doi.org/10.1111/j.1365-2338.2009.02234.x

(2009) PM 8/2(1): Coniferae. EPPO Bulletin 39, 420-449.  http://dx.doi.org/10.1111/j.1365-2338.2009.02311.x

(2009) 3rd BBBB-Bosphorus International Conference on Pharmaceutical Sciences. European Journal of Pharmaceutical Sciences 38, S1-S220.  http://www.sciencedirect.com/science/article/pii/S0928098709002747

Ackland SP, Bull JM and Boyle FM (2009) Nab-Paclitaxel: a bright new SPARC in taxane therapy of cancer. Asia-Pacific Journal of Clinical Oncology 5, 147-150.  http://dx.doi.org/10.1111/j.1743-7563.2009.01233.x

AgÜeros M, Ruiz-GatÓn L, Vauthier C, Bouchemal K, Espuelas S, Ponchel G and Irache JM (2009) Combined hydroxypropyl-β-cyclodextrin and poly(anhydride) nanoparticles improve the oral permeability of paclitaxel. European Journal of Pharmaceutical Sciences 38, 405-413.  http://www.sciencedirect.com/science/article/pii/S0928098709002693

Andraos J (2009) Application of Green Metrics Analysis to Chemical Reactions and Synthesis Plans. In ‘Green Chemistry Metrics’ (Ed.^(Eds  pp. 69-199. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781444305432.ch4

Anterola A, Shanle E, Perroud PF and Quatrano R (2009) Production of taxa-4(5),11(12)-diene by transgenic Physcomitrella patens. Transgenic Res 18, 655-60.

Beyer J (2009) Poisons: Detection of Naturally Occurring Poisons. In ‘Wiley Encyclopedia of Forensic Science’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470061589.fsa517

Borges KB, Borges WdS, DurÁn-PatrÓn R, Pupo MnT, Bonato PS and Collado IGl (2009) Stereoselective biotransformations using fungi as biocatalysts. Tetrahedron: Asymmetry 20, 385-397.  http://www.sciencedirect.com/science/article/pii/S0957416609001013

Brandt W, BrÄuer L, et al. (2009) Molecular and structural basis of metabolic diversity mediated by prenyldiphosphate converting enzymes. Phytochemistry 70, 1758-1775.  http://www.sciencedirect.com/science/article/pii/S0031942209003744

Brandt W, Bräuer L, et al. (2009) Molecular and structural basis of metabolic diversity mediated by prenyldiphosphate converting enzymes. Phytochemistry 70, 1758-1775.  http://www.sciencedirect.com/science/article/pii/S0031942209003744

Brioschi AM, Calderoni S, Zara GP, Priano L, Gasco MR, Mauro A and Hari Shanker S (2009) Chapter 11 - Solid lipid nanoparticles for brain tumors therapy: State of the art and novel challenges. In ‘Progress in Brain Research’ (Ed.^(Eds  pp. 193-223. (Elsevier). http://www.sciencedirect.com/science/article/pii/S0079612308800118

Casado P, Prado MA, et al. (2009) Microtubule interfering agents and KSP inhibitors induce the phosphorylation of the nuclear protein p54nrb, an event linked to G2/M arrest. Journal of Proteomics 71, 592-600.  http://www.sciencedirect.com/science/article/pii/S1874391908001371

Castells M (2009) Rapid Desensitization for Hypersensitivity Reactions to Medications. Immunology and Allergy Clinics of North America 29, 585-606.  http://www.sciencedirect.com/science/article/pii/S0889856109000356

Castro JS, Trzaskowski B, Deymier PA, Bucay J, Adamowicz L and Hoying JB (2009) Binding affinity of fluorochromes and fluorescent proteins to Taxol™ crystals. Materials Science and Engineering: C 29, 1609-1615.  http://www.sciencedirect.com/science/article/pii/S0928493108003937

Chaer GM, Myrold DD and Bottomley PJ (2009) A soil quality index based on the equilibrium between soil organic matter and biochemical properties of undisturbed coniferous forest soils of the Pacific Northwest. Soil Biology and Biochemistry 41, 822-830.  http://www.sciencedirect.com/science/article/pii/S0038071709000443

Chemier JA, Fowler ZL and Koffas MAG (2009) Trends In Microbial Synthesis of Natural Products and Biofuels. In ‘Advances in Enzymology and Related Areas of Molecular Biology’ (Ed.^(Eds  pp. 151-217. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470392881.ch4

Chen J-C, Lu K-W, et al. (2009) Gypenosides induced G0/G1 arrest via CHk2 and apoptosis through endoplasmic reticulum stress and mitochondria-dependent pathways in human tongue cancer SCC-4 cells. Oral Oncology 45, 273-283.  http://www.sciencedirect.com/science/article/pii/S136883750800167X

Chen L, Chen D, et al. (2009) Concomitant use of Ad5/35 chimeric oncolytic adenovirus with TRAIL gene and taxol produces synergistic cytotoxicity in gastric cancer cells. Cancer Letters 284, 141-148.  http://www.sciencedirect.com/science/article/pii/S0304383509002778

Chen Y, Guo H, Du Z, Liu XZ, Che Y and Ye X (2009) Ecology-based screen identifies new metabolites from a Cordyceps-colonizing fungus as cancer cell proliferation inhibitors and apoptosis inducers. Cell Proliferation 42, 838-847.  http://dx.doi.org/10.1111/j.1365-2184.2009.00636.x

Choi J, Konno T, Takai M and Ishihara K (2009) Controlled drug release from multilayered phospholipid polymer hydrogel on titanium alloy surface. Biomaterials 30, 5201-5208.  http://www.sciencedirect.com/science/article/pii/S0142961209006048

Chu H, Liu N, Wang X, Jiao Z and Chen Z (2009) Morphology and in vitro release kinetics of drug-loaded micelles based on well-defined PMPC–b–PBMA copolymer. International Journal of Pharmaceutics 371, 190-196.  http://www.sciencedirect.com/science/article/pii/S037851730800865X

Chu H, Liu N, Wang X, Jiao Z and Chen Z (2009) Morphology and in vitro release kinetics of drug-loaded micelles based on well-defined PMPC–b–PBMA copolymer. International Journal of Pharmaceutics 371, 190-196.  http://www.sciencedirect.com/science/article/pii/S037851730800865X

Cohen PR (2009) Photodistributed erythema multiforme: paclitaxel-related, photosensitive conditions in patients with cancer. J Drugs Dermatol 8, 61-4.

Compagnoni A and Halpern CB (2009) Properties of native plant communities do not determine exotic success during early forest succession. Ecography 32, 449-458.  http://dx.doi.org/10.1111/j.1600-0587.2008.05739.x

Dahm P, Engels B, Scholz S and Jennewein S (2009) Metabolic engineering of taxane biosynthesis in Saccharomyces cerevisiae. New Biotechnology 25, Supplement, S332-S333.  http://www.sciencedirect.com/science/article/pii/S187167840900942X

Danhier F, Lecouturier N, Vroman Bt, JÉrĂ´me C, Marchand-Brynaert J, Feron O and PrÉat Vr (2009) Paclitaxel-loaded PEGylated PLGA-based nanoparticles: In vitro and in vivo evaluation. Journal of Controlled Release 133, 11-17.  http://www.sciencedirect.com/science/article/pii/S0168365908006196

Danhier F, Vroman Bt, et al. (2009) Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with Paclitaxel. Journal of Controlled Release 140, 166-173.  http://www.sciencedirect.com/science/article/pii/S0168365909005471

Desai NP (2009) Systemic Paclitaxel for Prevention of Restenosis. In ‘Pharmacology in the Catheterization Laboratory’ (Ed.^(Eds  pp. 321-327. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781444306347.ch41

Dewick PM (2009) The Mevalonate and Methylerythritol Phosphate Pathways: Terpenoids and Steroids. In ‘Medicinal Natural Products’ (Ed.^(Eds  pp. 187-310. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470742761.ch5

Dosio F, Arpicco S, Stella B, Brusa P and Cattel L (2009) Folate-mediated targeting of albumin conjugates of paclitaxel obtained through a heterogeneous phase system. International Journal of Pharmaceutics 382, 117-123.  http://www.sciencedirect.com/science/article/pii/S0378517309005663

Duquesnoy E, Paoli M, Castola V, Bighelli A and Casanova J (2009) Identification of taxanes in extracts from leaves of Taxus baccata L. using 13C-NMR spectroscopy. Phytochemical Analysis 20, 246-252.  http://dx.doi.org/10.1002/pca.1121

ExpÓsito O, Bonfill M, Onrubia M, JanÉ A, Moyano E, CusidÓ RM, PalazÓn J and Piñol MT (2009) Effect of taxol feeding on taxol and related taxane production in Taxus baccata suspension cultures. New Biotechnology 25, 252-259.  http://www.sciencedirect.com/science/article/pii/S1871678408001143

Expósito O, Bonfill M, Onrubia M, Jané A, Moyano E, Cusidó RM, Palazón J and Pińol MT (2009) Effect of taxol feeding on taxol and related taxane production in Taxus baccata suspension cultures. New Biotechnology 25, 252-259.  http://www.sciencedirect.com/science/article/pii/S1871678408001143

Flavia M (2009) Chapter 2 From Microbial Products to Novel Drugs that Target a Multitude of Disease Indications. In ‘Methods in Enzymology’ (Ed.^(Eds David AH) pp. 29-58. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0076687909048022

Frishman WH, Beravol P and Carosella C (2009) Alternative and Complementary Medicine for Preventing and Treating Cardiovascular Disease. Disease-a-Month 55, 121-192.  http://www.sciencedirect.com/science/article/pii/S0011502908001594

Fu Y-J, Sun R, Zu Y-G, Li S-M, Liu W, Efferth T, Gu C-B, Zhang L and Luo H (2009) Simultaneous determination of main taxoids in Taxus needles extracts by solid-phase extraction-high-performance liquid chromatography with pentafluorophenyl column. Biomedical Chromatography 23, 63-70.  http://dx.doi.org/10.1002/bmc.1085

Galloway JM, Doherty CT, Patterson RT and Roe HM (2009) Postglacial vegetation and climate dynamics in the Seymour-Belize Inlet Complex, central coastal British Columbia, Canada: palynological evidence from Tiny Lake. Journal of Quaternary Science 24, 322-335.  http://dx.doi.org/10.1002/jqs.1232

Gangadevi V and Muthumary J (2009) Taxol production by Pestalotiopsis terminaliae, an endophytic fungus of Terminalia arjuna (arjun tree). Biotechnology and Applied Biochemistry 52, 9-15.  http://dx.doi.org/10.1042/BA20070243

Geller JI, Wall D, Perentesis J, Blaney SM and Bernstein M (2009) Phase I study of paclitaxel with standard dose ifosfamide in children with refractory solid tumors: A Pediatric Oncology Group study (POG 9376). Pediatric Blood & Cancer 52, 346-350.  http://dx.doi.org/10.1002/pbc.21820

Gertsch Jr (2009) How scientific is the science in ethnopharmacology? Historical perspectives and epistemological problems. Journal of Ethnopharmacology 122, 177-183.  http://www.sciencedirect.com/science/article/pii/S0378874109000270

Goldring WPD, Pattenden G and Rimmington SL (2009) Synthesis of a tetraoxy-bis-nortaxadiene, en route to taxol, using a cascade radical cyclisation sequence. Tetrahedron 65, 6670-6681.  http://www.sciencedirect.com/science/article/pii/S0040402009005705

Hayat S, Hasan SA, Mori M, Fariduddin Q and Ahmad A (2009) Nitric Oxide: Chemistry, Biosynthesis, and Physiological Role. In ‘Nitric Oxide in Plant Physiology’ (Ed.^(Eds  pp. 1-16. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527629138.ch1

Hodge M, Chen Q-H, Bane S, Sharma S, Loew M, Banerjee A, Alcaraz AA, Snyder JP and Kingston DGI (2009) Synthesis and bioactivity of a side chain bridged paclitaxel: A test of the T-Taxol conformation. Bioorganic &amp; Medicinal Chemistry Letters 19, 2884-2887.  http://www.sciencedirect.com/science/article/pii/S0960894X09003448

Hoffman A and Shahidi F (2009) Paclitaxel and other taxanes in hazelnut. Journal of Functional Foods 1, 33-37.  http://www.sciencedirect.com/science/article/pii/S1756464608000054

Hsiao JR, Leu SF and Huang BM (2009) Apoptotic mechanism of paclitaxel-induced cell death in human head and neck tumor cell lines. Journal of Oral Pathology & Medicine 38, 188-197.  http://dx.doi.org/10.1111/j.1600-0714.2008.00732.x

Huang H-H, He C-L, Wang H-S and Mo X-M (2009) Preparation of core-shell biodegradable microfibers for long-term drug delivery. Journal of Biomedical Materials Research Part A 90A, 1243-1251.  http://dx.doi.org/10.1002/jbm.a.32543

Ishii H, Yoshimura K-I and Mori A (2009) Convergence of leaf display and photosynthetic characteristics of understory Abies amabilis and Tsuga heterophylla in an old-growth forest in southwestern Washington State, USA. Tree Physiol 29, 989-998.  http://treephys.oxfordjournals.org/cgi/content/abstract/29/8/989

Jauhari S, Singh S, Dash AK and Harry GB (2009) Chapter 7 Paclitaxel. In ‘Profiles of Drug Substances, Excipients and Related Methodology’ (Ed.^(Eds  pp. 299-344. (Academic Press). http://www.sciencedirect.com/science/article/pii/S1871512509340078

Javeed A, Ashraf M, Riaz A, Ghafoor A, Afzal S and Mukhtar MM (2009) Paclitaxel and immune system. European Journal of Pharmaceutical Sciences 38, 283-290.  http://www.sciencedirect.com/science/article/pii/S0928098709002449

Jeon K-Y and Kim J-H (2009) Improvement of fractional precipitation process for pre-purification of paclitaxel. Process Biochemistry 44, 736-741.  http://www.sciencedirect.com/science/article/pii/S1359511309000877

Jilaveanu LB, Aziz SA and Kluger HM (2009) Chemotherapy and biologic therapies for melanoma: do they work? Clinics in Dermatology 27, 614-625.  http://www.sciencedirect.com/science/article/pii/S0738081X08001971

Jin CW, Du ST, Zhang YS, Lin XY and Tang CX (2009) Differential regulatory role of nitric oxide in mediating nitrate reductase activity in roots of tomato (Solanum lycocarpum). Ann. Bot. 104, 9-17.  http://aob.oxfordjournals.org/cgi/content/abstract/104/1/9

Kuder CH, Neighbors JD, Hohl RJ and Wiemer DF (2009) Synthesis and biological activity of a fluorescent schweinfurthin analogue. Bioorganic &amp; Medicinal Chemistry 17, 4718-4723.  http://www.sciencedirect.com/science/article/pii/S0968089609004118

Kumaran RS and Hur B-K (2009) Screening of species of the endophytic fungus Phomopsis for the production of the anticancer drug taxol. Biotechnology and Applied Biochemistry 54, 21-30.  http://dx.doi.org/10.1042/BA20080110

Kusari S, Lamshöft M and Spiteller M (2009) Aspergillus fumigatus Fresenius, an endophytic fungus from Juniperus communis L. Horstmann as a novel source of the anticancer pro-drug deoxypodophyllotoxin. Journal of Applied Microbiology 107, 1019-1030.  http://dx.doi.org/10.1111/j.1365-2672.2009.04285.x

Li S, Fu Y, Zu Y, Sun R, Wang Y, Zhang L, Luo H, Gu C and Efferth T (2009) Determination of paclitaxel and other six taxoids in Taxus species by high-performance liquid chromatography–tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 49, 81-89.  http://www.sciencedirect.com/science/article/pii/S0731708508005670

Li Y-C and Tao W-Y (2009) Interactions of Taxol-producing endophytic fungus with its host (Taxus spp.) during Taxol accumulation. Cell Biology International 33, 106-112.  http://www.sciencedirect.com/science/article/pii/S1065699508005969

Lozama A and Prisinzano TE (2009) Chemical methods for the synthesis and modification of neoclerodane diterpenes. Bioorganic & Medicinal Chemistry Letters 19, 5490-5495.  http://www.sciencedirect.com/science/article/pii/S0960894X09010312

Lu D, Williams PG and Wang G (2009) Metabolic Engineering for the Development and Manufacturing of Pharmaceuticals. In ‘Biocatalysis for the Pharmaceutical Industry’ (Ed.^(Eds  pp. 247-271. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470823163.ch12

Lu H-F, Sun X, Xu L, Lou L-G and Lin G-Q (2009) Design, synthesis and biological evaluation of novel fluorinated docetaxel analogues. European Journal of Medicinal Chemistry 44, 482-491.  http://www.sciencedirect.com/science/article/pii/S0223523408002055

Luo H, Nie Y-K, et al. (2009) Determination of main taxoids in Taxus species by microwave-assisted extraction combined with LC-MS/MS analysis. Journal of Separation Science 32, 192-201.  http://dx.doi.org/10.1002/jssc.200800527

Ma X and Wang Z (2009) Anticancer drug discovery in the future: an evolutionary perspective. Drug Discovery Today 14, 1136-1142.  http://www.sciencedirect.com/science/article/pii/S1359644609003316

Mallik AU and Richardson JS (2009) Riparian vegetation change in upstream and downstream reaches of three temperate rivers dammed for hydroelectric generation in British Columbia, Canada. Ecological Engineering 35, 810-819.  http://www.sciencedirect.com/science/article/pii/S0925857408002991

Margulis L and Chapman MJ (2009) Chapter Five - KINGDOM PLANTAE. In ‘Kingdoms and Domains’ (Ed.^(Eds  pp. 411-462. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780123736215000052

Marinelli F and David AH (2009) Chapter 2 From Microbial Products to Novel Drugs that Target a Multitude of Disease Indications. In ‘Methods in Enzymology’ (Ed.^(Eds  pp. 29-58. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0076687909048022

Menna-Barreto RFS, SalomĂŁo K, Dantas AiP, Santa-Rita RM, Soares MJ, Barbosa HS and de Castro SL (2009) Different cell death pathways induced by drugs in Trypanosoma cruzi: An ultrastructural study. Micron 40, 157-168.  http://www.sciencedirect.com/science/article/pii/S0968432808001893

Miller R (2009) Green Product Design. In ‘Green Chemistry Metrics’ (Ed.^(Eds  pp. 41-68. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781444305432.ch3

Miyato H, Kitayama J, Yamashita H, Souma D, Asakage M, Yamada J and Nagawa H (2009) Pharmacological Synergism Between Cannabinoids and Paclitaxel in Gastric Cancer Cell Lines. Journal of Surgical Research 155, 40-47.  http://www.sciencedirect.com/science/article/pii/S0022480408004526

Morgan-Hughes N (2009) Essentials of Cardiac Anesthesia. Br. J. Anaesth. 102, 287-.  http://bja.oxfordjournals.org

Napoleone E, Zurlo F, Latella MC, Amore C, Di Santo A, Iacoviello L, Donati MB and Lorenzet R (2009) Paclitaxel downregulates tissue factor in cancer and host tumour-associated cells. European Journal of Cancer 45, 470-477.  http://www.sciencedirect.com/science/article/pii/S0959804908008393

Nicolaou KC, Chen JS and Dalby SM (2009) From nature to the laboratory and into the clinic. Bioorganic & Medicinal Chemistry 17, 2290-2303.  http://www.sciencedirect.com/science/article/pii/S0968089608010390

Nobili S, Lippi D, Witort E, Donnini M, Bausi L, Mini E and Capaccioli S (2009) Natural compounds for cancer treatment and prevention. Pharmacological Research 59, 365-378.  http://www.sciencedirect.com/science/article/pii/S1043661809000516

Ong BYS, Ranganath SH, Lee LY, Lu F, Lee H-S, Sahinidis NV and Wang C-H (2009) Paclitaxel delivery from PLGA foams for controlled release in post-surgical chemotherapy against glioblastoma multiforme. Biomaterials 30, 3189-3196.  http://www.sciencedirect.com/science/article/pii/S0142961209002269

Ovaa H, Kuijl C and Neefjes J (2009) Recent and new targets for small molecule anti-cancer agents. Drug Discovery Today: Technologies 6, e3-e11.  http://www.sciencedirect.com/science/article/pii/S1740674910000028

Puskas JE, Muńoz-Robledo LG, Hoerr RA, Foley J, Schmidt SP, Evancho-Chapman M, Dong J, Frethem C and Haugstad G (2009) Drug-eluting stent coatings. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 1, 451-462.  http://dx.doi.org/10.1002/wnan.38

Qin J-C, Gao J-M, Zhang Y-M, Yang S-X, Bai M-S, Ma Y-T and Laatsch H (2009) Polyhydroxylated steroids from an endophytic fungus, Chaetomium globosum ZY-22 isolated from Ginkgo biloba. Steroids 74, 786-790.  http://www.sciencedirect.com/science/article/pii/S0039128X09001056

Qiu D, Pan X, Wilson IW, Li F, Liu M, Teng W and Zhang B (2009) High throughput sequencing technology reveals that the taxoid elicitor methyl jasmonate regulates microRNA expression in Chinese yew (Taxus chinensis). Gene 436, 37-44.  http://www.sciencedirect.com/science/article/pii/S0378111909000110

Rachelson A and Zilberman M (2009) Highly Porous Nano- and Microstructured Films Loaded with Bioactive Agents for Biomedical Applications: Structure—Release Profile Effects. Advanced Engineering Materials 11, B122-B128.  http://dx.doi.org/10.1002/adem.200800439

Reddy KP, Bid HK, Nayak VL, Chaudhary P, Chaturvedi JP, Arya KR, Konwar R and Narender T (2009) In vitro and in vivo anticancer activity of 2-deacetoxytaxinine J and synthesis of novel taxoids and their in vitro anticancer activity. European Journal of Medicinal Chemistry 44, 3947-3953.  http://www.sciencedirect.com/science/article/pii/S0223523409002219

Reisinger U, Schwaiger S, et al. (2009) Leoligin, the major lignan from Edelweiss, inhibits intimal hyperplasia of venous bypass grafts. Cardiovasc Res 82, 542-549.  http://cardiovascres.oxfordjournals.org/cgi/content/abstract/82/3/542

Ringold PL, Van Sickle J, Bollman M, Welty J and Barker J (2009) Riparian forest indicators of potential future stream condition. Ecological Indicators 9, 462-475.  http://www.sciencedirect.com/science/article/pii/S1470160X08000812

Sabel MS (2009) Chapter 16 - Principles of Adjuvant Chemotherapy for Breast Cancer. In ‘Essentials of Breast Surgery’ (Ed.^(Eds  pp. 247-266. (Mosby: Philadelphia). http://www.sciencedirect.com/science/article/pii/B9780323037587000168

Salgado I, de Oliveira HC and Braga MR (2009) Nitrate Reductase-Deficient Plants: A Model to Study Nitric Oxide Production and Signaling in Plant Defense Response to Pathogen Attack. In ‘Nitric Oxide in Plant Physiology’ (Ed.^(Eds  pp. 89-101. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527629138.ch7

Sirikantaramas S, Yamazaki M and Saito K (2009) A survival strategy: The coevolution of the camptothecin biosynthetic pathway and self-resistance mechanism. Phytochemistry 70, 1894-1898.  http://www.sciencedirect.com/science/article/pii/S0031942209003112

Soma D, Kitayama J, Ishigami H, Kaisaki S and Nagawa H (2009) Different Tissue Distribution of Paclitaxel With Intravenous and Intraperitoneal Administration. Journal of Surgical Research 155, 142-146.  http://www.sciencedirect.com/science/article/pii/S0022480408004563

Soma D, Kitayama J, Konno T, Ishihara K, Yamada J, Kamei T, Ishigami H, Kaisaki S and Nagawa H (2009) Intraperitoneal administration of paclitaxel solubilized with poly(2-methacryloxyethyl phosphorylcholine-co n-butyl methacrylate) for peritoneal dissemination of gastric cancer. Cancer Science 100, 1979-1985.  http://dx.doi.org/10.1111/j.1349-7006.2009.01265.x

Stadler M and Schulz B (2009) High energy biofuel from endophytic fungi? Trends in Plant Science 14, 353-355.  http://www.sciencedirect.com/science/article/pii/S1360138509001459

Sun Q, Liu C, Zhong H, Zhong B, Xu H, Shen W and Wang D (2009) Multi-center Phase II Trial of Weekly Paclitaxel Plus Cisplatin Combination Chemotherapy in Patients with Advanced Gastric and Gastro-esophageal Cancer. Jpn. J. Clin. Oncol. 39, 237-243.  http://jjco.oxfordjournals.org/cgi/content/abstract/39/4/237

Sun R, Fu K, Fu Y, Zu Y, Wang Y, Luo M, Li S, Luo H and Li Z (2009) Preparative separation and enrichment of four taxoids from Taxus chinensis needles extracts by macroporous resin column chromatography. Journal of Separation Science 32, 1284-1293.  http://dx.doi.org/10.1002/jssc.200800689

Tadych M, White JF and Editor-in-Chief:Â Â Moselio S (2009) Endophytic Microbes. In ‘Encyclopedia of Microbiology (Third Edition)’ (Ed.^(Eds  pp. 431-442. (Academic Press: Oxford). http://www.sciencedirect.com/science/article/pii/B978012373944500328X

Tan JPK, Kim SH, Nederberg F, Appel EA, Waymouth RM, Zhang Y, Hedrick JL and Yang YY (2009) Hierarchical Supermolecular Structures for Sustained Drug Release. Small 5, 1504-1507.  http://dx.doi.org/10.1002/smll.200801756

Tang W and Newton RJ (2009) Pines. In ‘Compendium of Transgenic Crop Plants’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781405181099.k0903

Tobias J and Hochhauser D (2009) Systemic Treatment for Cancer. In ‘Cancer and its Management’ (Ed.^(Eds  pp. 77-106. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781444306361.ch6

Ulrich-Merzenich G, Panek D, Zeitler H, Wagner H and Vetter H (2009) New perspectives for synergy research with the “omic”-technologies. Phytomedicine 16, 495-508.  http://www.sciencedirect.com/science/article/pii/S0944711309001056

Usera AR and O’Connor SE (2009) Mechanistic advances in plant natural product enzymes. Current Opinion in Chemical Biology 13, 492-498.  http://www.sciencedirect.com/science/article/pii/S1367593109000891

Usera AR and O’Connor SE (2009) Mechanistic advances in plant natural product enzymes. Current Opinion in Chemical Biology 13, 492-498.  http://www.sciencedirect.com/science/article/pii/S1367593109000891

Wang AC, Su QB, Wu FX, Zhang XL and Liu PS (2009) Role of TLR4 for paclitaxel chemotherapy in human epithelial ovarian cancer cells. European Journal of Clinical Investigation 39, 157-164.  http://dx.doi.org/10.1111/j.1365-2362.2008.02070.x

Wang Y-F, Su X-H, Li L-G, Wang W, Zhang M-L, Huo C-H and Shi Q-W (2009) Verticillane Derivatives from Natural Sources. Chemistry & Biodiversity 6, 1661-1673.  http://dx.doi.org/10.1002/cbdv.200700430

Weber W and Fussenegger M (2009) The impact of synthetic biology on drug discovery. Drug Discovery Today 14, 956-963.  http://www.sciencedirect.com/science/article/pii/S1359644609002220

Wharton S, Schroeder M, Bible K, Falk M and Paw U KT (2009) Stand-level gas-exchange responses to seasonal drought in very young versus old Douglas-fir forests of the Pacific Northwest, USA. Tree Physiol 29, 959-974.  http://treephys.oxfordjournals.org/cgi/content/abstract/29/8/959

Wharton S, Schroeder M, Paw U KT, Falk M and Bible K (2009) Turbulence considerations for comparing ecosystem exchange over old-growth and clear-cut stands for limited fetch and complex canopy flow conditions. Agricultural and Forest Meteorology 149, 1477-1490.  http://www.sciencedirect.com/science/article/pii/S0168192309000872

Wu M, Wu Y, Zhou J and Pan Y (2009) Structural characterisation of a water-soluble polysaccharide with high branches from the leaves of Taxus chinensis var. mairei. Food Chemistry 113, 1020-1024.  http://www.sciencedirect.com/science/article/pii/S0308814608010315

Yagi H, Yotsumoto F, Sonoda K, Kuroki M, Mekada E and Miyamoto S (2009) Synergistic anti-tumor effect of paclitaxel with CRM197, an inhibitor of HB-EGF, in ovarian cancer. International Journal of Cancer 124, 1429-1439.  http://dx.doi.org/10.1002/ijc.24031

Yang K-C, Tsai C-Y, Wang Y-J, Wei P-L, Lee C-H, Chen J-H, Wu C-H and Ho Y-S (2009) Apple polyphenol phloretin potentiates the anticancer actions of paclitaxel through induction of apoptosis in human hep G2 cells. Molecular Carcinogenesis 48, 420-431.  http://dx.doi.org/10.1002/mc.20480

Yang L, Tan T and Zhang L (2009) Process utilized oligo-β-cyclodextrin substituted agarose gel medium for efficient purification of paclitaxel from Taxus cuspidata. Separation and Purification Technology 68, 119-124.  http://www.sciencedirect.com/science/article/pii/S1383586609001816

Yang L, Tan T and Zhang L (2009) Process utilized oligo-β-cyclodextrin substituted agarose gel medium for efficient purification of paclitaxel from Taxus cuspidata. Separation and Purification Technology 68, 119-124.  http://www.sciencedirect.com/science/article/pii/S1383586609001816

Yang Y, Alcaraz AA and Snyder JP (2009) The Tubulin-Bound Conformation of Paclitaxel: T-Taxol vs “PTX-NY”. Journal of natural products. 72, 422-429.  http://dx.doi.org/10.1021/np800662j

Yin C, Pang X and Chen K (2009) The effects of water, nutrient availability and their interaction on the growth, morphology and physiology of two poplar species. Environmental and Experimental Botany 67, 196-203.  http://www.sciencedirect.com/science/article/pii/S0098847209001208

ZÁviŠovÁ V, KonerackÁ M, et al. (2009) Synthesis and characterization of polymeric nanospheres loaded with the anticancer drug paclitaxel and magnetic particles. Journal of Magnetism and Magnetic Materials 321, 1613-1616.  http://www.sciencedirect.com/science/article/pii/S0304885309001656

Zhang P, Zhou P-P and Yu L-J (2009) An endophytic taxol-producing fungus from Taxus x media, Aspergillus candidus MD3. FEMS Microbiology Letters 293, 155-159.  http://dx.doi.org/10.1111/j.1574-6968.2009.01481.x

Zhang Q and Azrak RG (2009) The effect of methylseleninic acid on paclitaxel efficacy in A2780 ovarian cancer cells. Journal of Nanjing Medical University 23, 111-116.  http://www.sciencedirect.com/science/article/pii/S100743760960037X

Zhao K, Ping W, Li Q, Hao S, Zhao L, Gao T and Zhou D (2009) Aspergillus niger var. taxi, a new species variant of taxol-producing fungus isolated from Taxus cuspidata in China. Journal of Applied Microbiology 107, 1202-1207.  http://dx.doi.org/10.1111/j.1365-2672.2009.04305.x

Zhou H, Zhang Z and Cheung H-Y (2009) Theoretical study on the reactive sites and intramolecular interactions in taxol and its four analogues. International Journal of Quantum Chemistry 109, 362-372.  http://dx.doi.org/10.1002/qua.21712

Zhou T-C, Zhou W-W, Hu W, Zhong J-J and Flickinger MC (2009) Bioreactors, Cell Culture, Commercial Production. In ‘Encyclopedia of Industrial Biotechnology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470054581.eib637

Zhou X, Zhong J-J and Flickinger MC (2009) Plant Cell Culture, Secondary Product Accumulation. In ‘Encyclopedia of Industrial Biotechnology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470054581.eib485

(2008) Index. In ‘Biotechnology Set’ (Ed.^(Eds  pp. 707-728. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527620999.index8

(2008) Subject Index. In ‘Medicinal Plant Biotechnology’ (Ed.^(Eds  pp. 543-571. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619771.indsub

Allison TD, Shimizu T, Ohara M and Yamanaka N (2008) Variation in sexual reproduction in Taxus cuspidata Sieb. & Zucc. Plant Species Biology 23, 25-32.  http://dx.doi.org/10.1111/j.1442-1984.2008.00204.x

Almeida B, Silva A, Mesquita A, Sampaio-Marques B, Rodrigues F and Ludovico P (2008) Drug-induced apoptosis in yeast. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1783, 1436-1448.  http://www.sciencedirect.com/science/article/pii/S0167488908000128

Azambuja E, Durbecq V, Rosa DD, Colozza M, Larsimont D, Piccart-Gebhart M and Cardoso F (2008) HER-2 overexpression/amplification and its interaction with taxane-based therapy in breast cancer. Ann. Onc. 19, 223-232.  http://annonc.oxfordjournals.org/cgi/content/abstract/19/2/223

Baker TM, Edmonds DJ, Hamilton D, O’Brien CJ and Procter DJ (2008) Synthesis and Reactions of the Pestalotiopsin Skeleton. Angewandte Chemie 120, 5713-5715.  http://dx.doi.org/10.1002/ange.200801900

Baldi A, Bisaria VS and Srivastava AK (2008) Biotechnological Approaches for the Production of some Promising Plant-Based Chemotherapeutics. In ‘Medicinal Plant Biotechnology’ (Ed.^(Eds  pp. 117-156. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619771.ch7

Barceloux DG (2008) Yew (Taxus Species). In ‘Medical Toxicology of Natural Substances’ (Ed.^(Eds  pp. 899-903. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470330319.ch163

Berlin J (2008) Secondary Products from Plant Cell Cultures. In ‘Biotechnology’ (Ed.^(Eds  pp. 593-640. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527620890.ch13

Bohlmann J and Keeling CI (2008) Terpenoid biomaterials. The Plant Journal 54, 656-669.  http://dx.doi.org/10.1111/j.1365-313X.2008.03449.x

Breathnach SM (2008) Drug Reactions. In ‘Rook’s Textbook of Dermatology’ (Ed.^(Eds  pp. 3765-3944. (Blackwell Publishing, Inc.). http://dx.doi.org/10.1002/9780470750520.ch73

Brower V (2008) Back to Nature: Extinction of Medicinal Plants Threatens Drug Discovery. J Natl Cancer Inst 100, 838-839.  http://jnci.oxfordjournals.org

Brown I, Sangrithi-Wallace JN and Schofield AC (2008) Antimicrotubule Agents. In ‘Anticancer Therapeutics’ (Ed.^(Eds  pp. 79-89. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470697047.ch6

Cardoso F, de Azambuja E and Lago LD (2008) Current perspectives of epothilones in breast cancer. European Journal of Cancer 44, 341-352.  http://www.sciencedirect.com/science/article/pii/S095980490700963X

Chen K, Huzil JT, Freedman H, Ramachandran P, Antoniou A, Tuszynski JA and Kurgan L (2008) Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing. Journal of Molecular Graphics and Modelling 27, 497-505.  http://www.sciencedirect.com/science/article/pii/S1093326308001046

Cheng J-S, Xu Q-M, Wu J-C and Yuan Y-J (2008) ERK-like MAPK signaling and cytochrome c response to oleic acid in two-liquid-phase suspension cultures of Taxus cuspidata. Biochemical Engineering Journal 41, 274-279.  http://www.sciencedirect.com/science/article/pii/S1369703X08001745

Chougule PB, Akhtar MS, et al. (2008) Concurrent chemoradiotherapy with weekly paclitaxel and carboplatin for locally advanced head and neck cancer: Long-term follow-up of a Brown University Oncology Group Phase II Study (HN-53). Head & Neck 30, 289-296.  http://dx.doi.org/10.1002/hed.20700

Daintree LS, Kordikowski A and York P (2008) Separation processes for organic molecules using SCF Technologies. Advanced Drug Delivery Reviews 60, 351-372.  http://www.sciencedirect.com/science/article/pii/S0169409X07002554

Desai A, Vyas T and Amiji M (2008) Cytotoxicity and apoptosis enhancement in brain tumor cells upon coadministration of paclitaxel and ceramide in nanoemulsion formulations. Journal of Pharmaceutical Sciences 97, 2745-2756.  http://dx.doi.org/10.1002/jps.21182

Dong P-p, Zhang Y-y, Ge G-b, Ai C-z, Liu Y, Yang L and Liu C-x (2008) Modeling resistance index of taxoids to MCF-7 cell lines using ANN together with electrotopological state descriptors1. Acta Pharmacologica Sinica 29, 385-396.  http://dx.doi.org/10.1111/j.1745-7254.2008.00746.x

Dong Y, Zhang Z and Feng S-S (2008) d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) modified poly(l-lactide) (PLLA) films for localized delivery of paclitaxel. International Journal of Pharmaceutics 350, 166-171.  http://www.sciencedirect.com/science/article/pii/S0378517307007326

François C (2008) Chapter 1 - A History of Drug Discovery: From first steps of chemistry to achievements in molecular pharmacology. In ‘The Practice of Medicinal Chemistry (Third Edition)’ (Ed.^(Eds Camille Georges W) pp. 1-62. (Academic Press: New York). http://www.sciencedirect.com/science/article/pii/B9780123741943000019

Frisvold G and Day-Rubenstein K (2008) Bioprospecting and Biodiversity Conservation: What Happens When Discoveries are Made? Arizona law review. 50, 2.  http://hdl.handle.net/10113/44112

Furey A and Tassell M (2008) Towards a systematic scientific approach in the assessment of efficacy of an herbal preparation: Hawthorn (Crataegus spp.). Eur J Heart Fail 10, 1153-1157.  http://eurjhf.oxfordjournals.org

Gangadevi V, Murugan M and Muthumary J (2008) Taxol Determination from Pestalotiopsis pauciseta, a Fungal Endophyte of a Medicinal Plant. Chinese Journal of Biotechnology 24, 1433-1438.  http://www.sciencedirect.com/science/article/pii/S1872207508600655

Gräfe U, Dornberger K and Saluz H-P (2008) Biotechnical Drugs as Antitumor Agents. In ‘Biotechnology’ (Ed.^(Eds  pp. 641-705. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527620890.ch14

Gräfe U, Dornberger K and Saluz H-P (2008) Biotechnical Drags as Antitumor Agents. In ‘Biotechnology Set’ (Ed.^(Eds  pp. 641-705. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527620999.ch14g

GrÜNwald NJ, Goss EM and Press CM (2008) Phytophthora ramorum: a pathogen with a remarkably wide host range causing sudden oak death on oaks and ramorum blight on woody ornamentals. Molecular Plant Pathology 9, 729-740.  http://dx.doi.org/10.1111/j.1364-3703.2008.00500.x

Guimarăes DO, Borges WS, et al. (2008) Biological activities from extracts of endophytic fungi isolated from Viguiera arenaria and Tithonia diversifolia. FEMS Immunology & Medical Microbiology 52, 134-144.  http://dx.doi.org/10.1111/j.1574-695X.2007.00354.x

Haggarty SJ and Schreiber SL (2008) Forward Chemical Genetics. In ‘Chemical Biology’ (Ed.^(Eds  pp. 299-354. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619375.ch6

Hao DC, Ge GB and Yang L (2008) Bacterial diversity of Taxus rhizosphere: culture-independent and culture-dependent approaches. FEMS Microbiology Letters 284, 204-212.  http://dx.doi.org/10.1111/j.1574-6968.2008.01201.x

Horiguchi T, Rithner CD, Croteau R and Williams RM (2008) Studies on Taxol® biosynthesis. Preparation and tritium labeling of biosynthetic intermediates by deoxygenation of a taxadiene tetra-acetate obtained from Japanese yew. Journal of Labelled Compounds and Radiopharmaceuticals 51, 325-328.  http://dx.doi.org/10.1002/jlcr.1529

Hsu P-C, Hung H-C, Liao Y-F, Liu C-C, Tsay GJ and Liu G-Y (2008) Ornithine decarboxylase attenuates leukemic chemotherapy drugs-induced cell apoptosis and arrest in human promyelocytic HL-60 cells. Leukemia Research 32, 1530-1540.  http://www.sciencedirect.com/science/article/pii/S0145212608000568

Jiang S, Zu Y, Fu Y, Zhang Y and Efferth T (2008) Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel. Int J Oncol 33, 103-11.

Jordan MA, Horwitz SB, Lobert S and Correia JJ (2008) Exploring the Mechanisms of Action of the Novel Microtubule Inhibitor Vinflunine. Seminars in Oncology 35, Supplement 3, S6-S12.  http://www.sciencedirect.com/science/article/pii/S0093775408000183

Kozielski F, Skoufias DA, Indorato R-L, Saoudi Y, Jungblut PR, Hustoft HK, Strozynski M and Thiede B (2008) Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5. PROTEOMICS 8, 289-300.  http://dx.doi.org/10.1002/pmic.200700534

Kraitzer A, Kloog Y and Zilberman M (2008) Approaches for prevention of restenosis. Journal of Biomedical Materials Research Part B: Applied Biomaterials 85B, 583-603.  http://dx.doi.org/10.1002/jbm.b.30974

Kumaran RS, Muthumary J and Hur B-K (2008) Taxol from Phyllosticta citricarpa, a leaf spot fungus of the angiosperm Citrus medica. Journal of Bioscience and Bioengineering 106, 103-106.  http://www.sciencedirect.com/science/article/pii/S1389172308701506

Lamari FN and Cordopatis P (2008) Exploring the Potential of Natural Products in Cancer Treatment. In ‘Anticancer Therapeutics’ (Ed.^(Eds  pp. 1-16. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470697047.ch1

Lao LL and Venkatraman SS (2008) Paclitaxel release from single and double-layered poly(DL-lactide-co-glycolide)/poly(L-lactide) film for biodegradable coronary stent application. Journal of Biomedical Materials Research Part A 87A, 1-7.  http://dx.doi.org/10.1002/jbm.a.31706

Li C, Huo C, Zhang M and Shi Q (2008) Chemistry of Chinese yew, Taxus chinensis var. mairei. Biochemical Systematics and Ecology 36, 266-282.  http://www.sciencedirect.com/science/article/pii/S030519780700172X

M. Hagel J, E. Page J and J. Facchini P (2008) Impact of Whole-Genome and Expressed Sequence Tag Databases on the Study of Plant Secondary Metabolism. In ‘Medicinal Plant Biotechnology’ (Ed.^(Eds  pp. 203-236. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619771.ch10

Matsubara J, Shimada Y, et al. (2008) A Phase I Study of Bolus 5-Fluorouracil and Leucovorin Combined with Weekly Paclitaxel (FLTAX) as First-line Therapy for Advanced Gastric Cancer. Jpn. J. Clin. Oncol. 38, 540-546.  http://jjco.oxfordjournals.org/cgi/content/abstract/38/8/540

Maurie M (2008) The remarkable “paclitaxel story”: How many chapters remain to be written? Gynecologic Oncology 111, 7-8.  http://www.sciencedirect.com/science/article/pii/S0090825808004952

Miller K, Neilan B and Sze DM (2008) Development of Taxol and other endophyte produced anti-cancer agents. Recent Pat Anticancer Drug Discov 3, 14-9.

Mori AS, Mizumachi E and Sprugel DG (2008) Morphological acclimation to understory environments in Abies amabilis, a shade- and snow-tolerant conifer species of the Cascade Mountains, Washington, USA. Tree Physiol 28, 815-824.  http://treephys.oxfordjournals.org/cgi/content/abstract/28/5/815

Newman DJ, Cragg GM and I. Kingston DG (2008) Chapter 8 - Natural Products as Pharmaceuticals and Sources for Lead Structures. In ‘The Practice of Medicinal Chemistry (Third Edition)’ (Ed.^(Eds Camille Georges W) pp. 159-186. (Academic Press: New York). http://www.sciencedirect.com/science/article/pii/B9780123741943000081

Nisar M, Khan I, Simjee SU, Gilani AH, Obaidullah and Perveen H (2008) Anticonvulsant, analgesic and antipyretic activities of Taxus wallichiana Zucc. Journal of Ethnopharmacology 116, 490-494.  http://www.sciencedirect.com/science/article/pii/S037887410800010X

Norman TR (2008) How does your garden grow—therapeutic principles from herbal remedies? Stress and Health 24, 1-2.  http://dx.doi.org/10.1002/smi.1179

Nornoo AO and Chow DSL (2008) Cremophor-free intravenous microemulsions for paclitaxel: II. Stability, in vitro release and pharmacokinetics. International Journal of Pharmaceutics 349, 117-123.  http://www.sciencedirect.com/science/article/pii/S0378517307006473

Nybom H and Weising K (2008) DNA Profiling of Plants. In ‘Medicinal Plant Biotechnology’ (Ed.^(Eds  pp. 73-95. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619771.ch5

Ottaggio L, Bestoso F, Armirotti A, Balbi A, Damonte G, Mazzei M, Sancandi M and Miele M (2008) Taxanes from Shells and Leaves of Corylus avellana. J Nat Prod 71, 58-60.

Qiao W and Fan L-M (2008) Nitric Oxide Signaling in Plant Responses to Abiotic Stresses. Journal of Integrative Plant Biology 50, 1238-1246.  http://dx.doi.org/10.1111/j.1744-7909.2008.00759.x

Régina A, Demeule M, Ché C, Lavallée I, Poirier J, Gabathuler R, Béliveau R and Castaigne JP (2008) Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2. British Journal of Pharmacology 155, 185-197.  http://dx.doi.org/10.1038/bjp.2008.260

Rook J, Rosser T, Fangusaro J and Finlay J (2008) Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma. Pediatric Blood & Cancer 50, 699-700.  http://dx.doi.org/10.1002/pbc.21040

Ryan RP, Germaine K, Franks A, Ryan DJ and Dowling DN (2008) Bacterial endophytes: recent developments and applications. FEMS Microbiology Letters 278, 1-9.  http://dx.doi.org/10.1111/j.1574-6968.2007.00918.x

Saklani A and Kutty SK (2008) Plant-derived compounds in clinical trials. Drug Discovery Today 13, 161-171.  http://www.sciencedirect.com/science/article/pii/S1359644607004242

Schmidt-Dannert C and Pisarchik A (2008) Biosynthetic Pathway Engineering Strategies. In ‘Protein Engineering Handbook’ (Ed.^(Eds  pp. 849-876. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527634026.ch34

Senthil Kumaran R, Muthumary J and Hur BK (2008) Production of Taxol fromPhyllosticta spinarum, an endophytic fungus ofCupressus sp. Engineering in Life Sciences 8, 438-446.  http://dx.doi.org/10.1002/elsc.200800019

Shah A, Li D-Z, Gao L-M, Li H-T and Möller M (2008) Genetic diversity within and among populations of the endangered species Taxus fuana (Taxaceae) from Pakistan and implications for its conservation. Biochemical Systematics and Ecology 36, 183-193.  http://www.sciencedirect.com/science/article/pii/S0305197807002050

Shen H, Hu D, et al. (2008) Paclitaxel–octreotide conjugates in tumor growth inhibition of A549 human non-small cell lung cancer xenografted into nude mice. European Journal of Pharmacology 601, 23-29.  http://www.sciencedirect.com/science/article/pii/S0014299908010613

Sherman DM (2008) Preservation of Biodiversity, Wildlife, and Conservation Medicine. In ‘Tending Animals in the Global Village’ (Ed.^(Eds  pp. 245-304. (Lippincott Williams & Wilkins). http://dx.doi.org/10.1002/9780470292136.ch7

Sherman DM (2008) The Global Society and Veterinary Medicine. In ‘Tending Animals in the Global Village’ (Ed.^(Eds  pp. 1-24. (Lippincott Williams & Wilkins). http://dx.doi.org/10.1002/9780470292136.ch1

Singh P, Rathinasamy K, Mohan R and Panda D (2008) Microtubule assembly dynamics: An attractive target for anticancer drugs. IUBMB Life 60, 368-375.  http://dx.doi.org/10.1002/iub.42

Strobel G (2008) Plant-Associated Microorganisms (Endophytes) as a New Source of Bioactive Natural Products. In ‘Medicinal Plant Biotechnology’ (Ed.^(Eds  pp. 49-72. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619771.ch4

Susan Band H (2008) Introduction. Seminars in Oncology 35, Supplement 3, S1-S2.  http://www.sciencedirect.com/science/article/pii/S0093775408000171

Tabata H (2008) Production of Paclitaxel in Plant Cell Cultures. In ‘Medicinal Plant Biotechnology’ (Ed.^(Eds  pp. 515-528. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619771.ch22

Takao K-i, Hayakawa N, Yamada R, Yamaguchi T, Morita U, Kawasaki S and Tadano K-i (2008) Total Synthesis of (−)-Pestalotiopsin A. Angewandte Chemie 120, 3474-3477.  http://dx.doi.org/10.1002/ange.200800253

Tsao AS (2008) New Chemotherapeutic Agents in Lung Cancer. In ‘Lung Cancer’ (Ed.^(Eds  pp. 315-333. (Blackwell Publishing Ltd). http://dx.doi.org/10.1002/9780470696330.ch20

Turley DB (2008) The Chemical Value of Biomass. In ‘Introduction to Chemicals from Biomass’ (Ed.^(Eds  pp. 21-46. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470697474.ch2

Vanisree M and Tsay H-S (2008) Plant Cell Cultures: Production of Biologically Important Secondary Metabolites from Medicinal Plants of Taiwan. In ‘Medicinal Plant Biotechnology’ (Ed.^(Eds  pp. 267-285. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619771.ch12

von Döhren H and Gräfe U (2008) General Aspects of Secondary Metabolism. In ‘Biotechnology’ (Ed.^(Eds  pp. 1-55. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527620890.ch1

Wargovich MJ, Hollis DM and Zander MES (2008) Herbals and Cancer Prevention. In ‘Functional Foods & Nutraceuticals in Cancer Prevention’ (Ed.^(Eds  pp. 237-262. (Iowa State Press). http://dx.doi.org/10.1002/9780470290194.ch14

Wessjohann LA (2008) The First Total Syntheses of Taxol. In ‘Organic Synthesis Set’ (Ed.^(Eds  pp. 295-305. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527620784.ch44b

Wilson DA (2008) Appendix VIII: Colloquial Tree Names. In ‘Forensic Procedures for Boundary and Title Investigation’ (Ed.^(Eds  pp. 403-415. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470260012.app8

(2007) Paclitaxel. In ‘Hawley’s Condensed Chemical Dictionary’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470114735.hawley12233

(2007) Index. In ‘Plant Secondary Metabolites’ (Ed.^(Eds  pp. 353-372. (Blackwell Publishing Ltd). http://dx.doi.org/10.1002/9780470988558.index

Bandara S, Diehl M and Fricker G (2007) A Mathematical Model for the Transport of Paclitaxel (Taxol) Across the Blood-Brain Barrier. Chemical Engineering Research and Design 85, 1065-1071.  http://www.sciencedirect.com/science/article/pii/S026387620773143X

Brancale A and Silvestri R (2007) Indole, a core nucleus for potent inhibitors of tubulin polymerization. Medicinal Research Reviews 27, 209-238.  http://dx.doi.org/10.1002/med.20080

Buwa LV and Van Staden J (2007) Effects of collection time on the antimicrobial activities of Harpephyllum caffrum bark. South African Journal of Botany 73, 242-247.  http://www.sciencedirect.com/science/article/pii/S0254629906001323

Chavan SP, Chavan SP, Sonawane HR, Kalkote UR, Sudrik SG, Gonnade RG and Bhadbhade MM (2007) Utilization of the Versatility of Sulfur in C–C Bond Formation and Cleavage: Synthesis of ABC Taxoid Skeletons. European Journal of Organic Chemistry 2007, 3277-3280.  http://dx.doi.org/10.1002/ejoc.200700301

Cheng A-X, Lou Y-G, Mao Y-B, Lu S, Wang L-J and Chen X-Y (2007) Plant Terpenoids: Biosynthesis and Ecological Functions. Journal of Integrative Plant Biology 49, 179-186.  http://dx.doi.org/10.1111/j.1744-7909.2007.00395.x

Court of Appeal (2007) ANGIOTECH PHARMACEUTICALS INC v CONOR MEDSYSTEMS INC. R.P.C. 124, 487-508.  http://rpc.oxfordjournals.org/cgi/content/abstract/124/13-14/487

Cox PA (2007) Ethnopharmacology and the Search for New Drugs. In ‘Ciba Foundation Symposium 154 - Bioactive Compounds from Plants’ (Ed.^(Eds  pp. 40-55. (John Wiley & Sons, Ltd.). http://dx.doi.org/10.1002/9780470514009.ch4

Cragg GM, Boyd MR, Cardellina JH, Newman DJ, Snader KM and McCloud TG (2007) Ethnobotany and Drug Discovery: The Experience of the US National Cancer Institute. In ‘Ciba Foundation Symposium 185 - Ethnobotany and the Search for New Drugs’ (Ed.^(Eds  pp. 178-196. (John Wiley & Sons, Ltd.). http://dx.doi.org/10.1002/9780470514634.ch13

David G.I K (2007) The shape of things to come: Structural and synthetic studies of taxol and related compounds. Phytochemistry 68, 1844-1854.  http://www.sciencedirect.com/science/article/pii/S0031942206006923

Dong Y and Feng S-S (2007) In vitro and in vivo evaluation of methoxy polyethylene glycol–polylactide (MPEG–PLA) nanoparticles for small-molecule drug chemotherapy. Biomaterials 28, 4154-4160.  http://www.sciencedirect.com/science/article/pii/S0142961207004425

Fojo T and Menefee M (2007) Mechanisms of multidrug resistance: the potential role of microtubule-stabilizing agents. Ann. Onc. 18, v3-8.  http://annonc.oxfordjournals.org/cgi/content/abstract/18/suppl_5/v3

Gao LM, MÖLler M, Zhang XM, Hollingsworth ML, Liu J, Mill RR, Gibby M and Li DZ (2007) High variation and strong phylogeographic pattern among cpDNA haplotypes in Taxus wallichiana (Taxaceae) in China and North Vietnam. Molecular Ecology 16, 4684-4698.  http://dx.doi.org/10.1111/j.1365-294X.2007.03537.x

Georgopoulou K, Smirlis D, Bisti S, Xingi E, Skaltsounis L and Soteriadou K (2007) In vitro activity of 10-deacetylbaccatin III against Leishmania donovani promastigotes and intracellular amastigotes. Planta medica. 73, 10.

Han J, Sun M, et al. (2007) Kushen flavonoids induce apoptosis in tumor cells by inhibition of NF-κB activation and multiple receptor tyrosine kinase activities. Phytotherapy Research 21, 262-268.  http://dx.doi.org/10.1002/ptr.2065

Heilmann J (2007) Wirkstoffe auf Basis biologisch aktiver Naturstoffe. Chemie in unserer Zeit 41, 376-389.  http://dx.doi.org/10.1002/ciuz.200700427

Huo C-H, Wang Y-F, Zhang X-P, Li C-F, Shi Q-W and Kiyota H (2007) A New Metabolite with a New Substitution Pattern from the Seeds of the Chinese Yew, Taxus mairei. Chemistry & Biodiversity 4, 84-88.  http://dx.doi.org/10.1002/cbdv.200790009

Ilson D, Wadleigh R, Leichman L and Kelsen D (2007) Paclitaxel given by a weekly 1-h infusion in advanced esophageal cancer. Ann. Onc. 18, 898-902.  http://annonc.oxfordjournals.org/cgi/content/abstract/18/5/898

Keeling CI, Bohlmann J and Begley TP (2007) Plant Terpenoids. In ‘Wiley Encyclopedia of Chemical Biology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470048672.wecb596

Kim S-H, Juhnn Y-S and Song Y-S (2007) Akt Involvement in Paclitaxel Chemoresistance of Human Ovarian Cancer Cells. Annals of the New York Academy of Sciences 1095, 82-89.  http://dx.doi.org/10.1196/annals.1397.012

Kim YH, Yamaguchi K, et al. (2007) Phase II Study of Biweekly Paclitaxel and Cisplatin Combination Chemotherapy in Advanced Gastric Cancer: Korea Japan Collaborative Study Group Trial. Jpn. J. Clin. Oncol. 37, 501-508.  http://jjco.oxfordjournals.org/cgi/content/abstract/37/7/501

Kingston DGI (2007) The shape of things to come: Structural and synthetic studies of taxol and related compounds. Phytochemistry. 68, 14.  http://dx.doi.org/10.1016/j.phytochem.2006.11.009

Kingston DGI, Newman DJ and Begley TP (2007) Natural Products as Anticancer Agents. In ‘Wiley Encyclopedia of Chemical Biology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470048672.wecb369

Lampson MA, Kapoor TM and Begley TP (2007) Unraveling Cell Division Mechanisms with Small-Molecule Inhibitors. In ‘Wiley Encyclopedia of Chemical Biology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470048672.wecb060

Lee K-H, Itokawa H, Akiyama T, Morris-Natschke SL and Begley TP (2007) Plant-Derived Natural Products Research: Recent Progress in Drug Discovery. In ‘Wiley Encyclopedia of Chemical Biology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470048672.wecb373

Lee KM, Cao D, Itami A, Pour PM, Hruban RH, Maitra A and Ouellette MM (2007) Class III β-tubulin, a marker of resistance to paclitaxel, is overexpressed in pancreatic ductal adenocarcinoma and intraepithelial neoplasia. Histopathology 51, 539-546.  http://dx.doi.org/10.1111/j.1365-2559.2007.02792.x

Legault J and Pichette A (2007) Potentiating effect of β-caryophyllene on anticancer activity of α-humulene, isocaryophyllene and paclitaxel. Journal of Pharmacy and Pharmacology 59, 1643-1647.  http://dx.doi.org/10.1211/jpp.59.12.0005

Leslie Gunatilaka A and Begley TP (2007) Natural Products in Plants: Chemical Diversity. In ‘Wiley Encyclopedia of Chemical Biology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470048672.wecb163

Malinowski J, Krzymowska M, Godoń K, Hennig J and Podstolski A (2007) A new catalytic activity from tobacco converting 2-coumaric acid to salicylic aldehyde. Physiologia Plantarum 129, 461-471.  http://dx.doi.org/10.1111/j.1399-3054.2006.00837.x

Marie J-P and Legrand O (2007) Multidrug Resistance in Leukaemia. In ‘Postgraduate Haematology’ (Ed.^(Eds  pp. 575-585. (Blackwell Publishing Ltd). http://dx.doi.org/10.1002/9780470987056.ch35

McChesney JD, Venkataraman SK and Henri JT (2007) Plant natural products: Back to the future or into extinction? Phytochemistry 68, 2015-2022.  http://www.sciencedirect.com/science/article/pii/S0031942207002920

Molyneux RJ, Lee ST, Gardner DR, Panter KE and James LF (2007) Phytochemicals: The good, the bad and the ugly? Phytochemistry 68, 2973-2985.  http://www.sciencedirect.com/science/article/pii/S0031942207005614

Montalbetti CAGN, Falque VM and Begley TP (2007) Synthetic Chemistry: Formation of the Amide Bond. In ‘Wiley Encyclopedia of Chemical Biology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470048672.wecb635

Mugnaini S, Nepi M, Guarnieri M, Piotto B and Pacini E (2007) Pollination Drop in Juniperus communis: Response to Deposited Material. Ann. Bot. 100, 1475-1481.  http://aob.oxfordjournals.org/cgi/content/abstract/100/7/1475

Nam W, Tak J, Ryu J-K, Jung M, Yook J-I, Kim H-J and Cha I-H (2007) Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells. Head & Neck 29, 335-340.  http://dx.doi.org/10.1002/hed.20524

Niinemets U, Lukjanova A, Turnbull MH and Sparrow AD (2007) Plasticity in mesophyll volume fraction modulates light-acclimation in needle photosynthesis in two pines. Tree Physiol 27, 1137-1151.  http://treephys.oxfordjournals.org/cgi/content/abstract/27/8/1137

O’Leary SJB, Poulis BAD and von Aderkas P (2007) Identification of two thaumatin-like proteins (TLPs) in the pollination drop of hybrid yew that may play a role in pathogen defence during pollen collection. Tree Physiol 27, 1649-1659.  http://treephys.oxfordjournals.org/cgi/content/abstract/27/12/1649

Papas S, Akoumianaki T, Kalogiros C, Hadjiarapoglou L, Theodoropoulos PA and Tsikaris V (2007) Synthesis and antitumor activity of peptide-paclitaxel conjugates. Journal of Peptide Science 13, 662-671.  http://dx.doi.org/10.1002/psc.899

Pauli GF, Jaki BU and Lankin DC (2007) A routine experimental protocol for qHNMR illustrated with Taxol. J Nat Prod 70, 589-95.

Prado MA, Casado P, Zuazua-Villar P, del Valle E, Artime N, Cabal-Hierro L, Martínez-Campa CM, Lazo PS and Ramos S (2007) Phosphorylation of human eukaryotic elongation factor 1Bγ is regulated by paclitaxel. PROTEOMICS 7, 3299-3304.  http://dx.doi.org/10.1002/pmic.200700226

Sienkiewicz P, Ciolino HP, Leslie BJ, Hergenrother PJ, Singletary K and Yeh GC (2007) A novel synthetic analogue of a constituent of Isodon excisus inhibits transcription of CYP1A1, -1A2 and -1B1 by preventing activation of the aryl hydrocarbon receptor. Carcinogenesis 28, 1052-1057.  http://carcin.oxfordjournals.org/cgi/content/abstract/28/5/1052

Singh SB and Begley TP (2007) Pharmaceuticals: Natural Products and Natural Product Models. In ‘Wiley Encyclopedia of Chemical Biology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470048672.wecb444

Singleton P and Sainsbury D (2007) T. In ‘Dictionary of Microbiology and Molecular Biology’ (Ed.^(Eds  pp. 758-811. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470056981.ch20

Souhami R and Tobias J (2007) Systemic Treatment for Cancer. In ‘Cancer and its Management’ (Ed.^(Eds  pp. 76-107. (Blackwell Science Ltd). http://dx.doi.org/10.1002/9780470994887.ch6

Sowemimo AA, Fakoya FA, Awopetu I, Omobuwajo OR and Adesanya SA (2007) Toxicity and mutagenic activity of some selected Nigerian plants. Journal of Ethnopharmacology 113, 427-432.  http://www.sciencedirect.com/science/article/pii/S0378874107003194

Spratlin J and Sawyer MB (2007) Pharmacogenetics of paclitaxel metabolism. Critical Reviews in Oncology/Hematology 61, 222-229.  http://www.sciencedirect.com/science/article/pii/S1040842806002022

Stordal B, Pavlakis N and Davey R (2007) A systematic review of platinum and taxane resistance from bench to clinic: An inverse relationship. Cancer Treatment Reviews 33, 688-703.  http://www.sciencedirect.com/science/article/pii/S0305737207000989

Su WW and Lee K-T (2007) Chapter 10 - Plant Cell and Hairy Root Cultures—Process Characteristics, Products, and Applications. In ‘Bioprocessing for Value-Added Products from Renewable Resources’ (Ed.^(Eds Shang-Tian Y) pp. 263-292. (Elsevier: Amsterdam). http://www.sciencedirect.com/science/article/pii/B9780444521149500116

Sugahara S-i, Kajiki M, Kuriyama H and Kobayashi T-r (2007) Complete regression of xenografted human carcinomas by a paclitaxel–carboxymethyl dextran conjugate (AZ10992). Journal of Controlled Release 117, 40-50.  http://www.sciencedirect.com/science/article/pii/S0168365906005724

Takeda M, Mizokami A, Mamiya K, Li YQ, Zhang J, Keller ET and Namiki M (2007) The establishment of two paclitaxel-resistant prostate cancer cell lines and the mechanisms of paclitaxel resistance with two cell lines. The Prostate 67, 955-967.  http://dx.doi.org/10.1002/pros.20581

Takimoto CH and Wick M (2007) Chapter 29 - Preclinical Drug Development. In ‘Principles of Clinical Pharmacology (Second Edition)’ (Ed.^(Eds Arthur JA, Jr, et al.) pp. 449-462. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780123694171500699

Vavra M, Hemstrom MA and Wisdom M (2007) Modeling the effects of herbivores on the abundance of forest overstory states using a state-transition approach in the upper Grande Ronde River Basin, Oregon, USA. Landscape and Urban Planning 80, 212-222.  http://www.sciencedirect.com/science/article/pii/S0169204606002209

Vincenzi B, Santini D, Frezza AM, Rocci L and Tonini G (2007) Docetaxel induced pericardial effusion. J Exp Clin Cancer Res 26, 417-20.

Vongpaseuth K, Nims E, Amand MS, Walker EL and Roberts SC (2007) Development of a Particle Bombardment-Mediated Transient Transformation System for Taxus spp. Cells in Culture. Biotechnology Progress 23, 1180-1185.  http://dx.doi.org/10.1021/bp0700307

Vongpaseuth K and Roberts SC (2007) Advancements in the understanding of Paclitaxel metabolism in tissue culture. Curr Pharm Biotechnol 8, 219-36.

Wang Y, Guo B, Miao Z and Tang K (2007) Transformation of taxol-producing endophytic fungi by restriction enzyme-mediated integration (REMI). FEMS Microbiology Letters 273, 253-259.  http://dx.doi.org/10.1111/j.1574-6968.2007.00801.x

Wang Y-D, Wu J-C and Yuan Y-J (2007) Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei. Cell Biology International 31, 1179-1183.  http://www.sciencedirect.com/science/article/pii/S1065699507001060

Warren JM, Meinzer FC, Brooks JR, Domec J-C and Coulombe R (2007) Hydraulic redistribution of soil water in two old-growth coniferous forests: quantifying patterns and controls. New Phytologist 173, 753-765.  http://dx.doi.org/10.1111/j.1469-8137.2006.01963.x

Wheeler DW, Liew TV and Bailey AR (2007) Peri-operative atrioventricular block as a result of chemotherapy with epirubicin and paclitaxel. Anaesthesia 62, 186-189.  http://dx.doi.org/10.1111/j.1365-2044.2006.04946.x

Wilson CR and Hooser SB (2007) Chapter 74 - Toxicity of yew (Taxus spp.) alkaloids. In ‘Veterinary Toxicology’ (Ed.^(Eds Ramesh CG, Dvm, et al.) pp. 929-935. (Academic Press: Oxford). http://www.sciencedirect.com/science/article/pii/B9780123704672501711

Wunderlich S, Zähres M, Jo B-W and Hess M (2007) Monitoring the Interaction of Albumin with a Paclitaxel-Polymer Conjugate: Complex with Warfarin as Local Probe. Macromolecular Symposia 258, 101-107.  http://dx.doi.org/10.1002/masy.200751211

Xie Z, Guan H, Chen X, Lu C, Chen L, Hu X, Shi Q and Jing X (2007) A novel polymer–paclitaxel conjugate based on amphiphilic triblock copolymer. Journal of Controlled Release 117, 210-216.  http://www.sciencedirect.com/science/article/pii/S0168365906006717

Yang C-G, Barasoain I, Li X, Matesanz R, Liu R, Sharom FJ, Yin D-L, Díaz JF and Fang W-S (2007) Overcoming Tumor Drug Resistance with High-Affinity Taxanes: A SAR Study of C2-Modified 7-Acyl-10-Deacetyl Cephalomannines. ChemMedChem 2, 691-701.  http://dx.doi.org/10.1002/cmdc.200700002

Yang T, Choi M-K, Cui F-D, Kim JS, Chung S-J, Shim C-K and Kim D-D (2007) Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome. Journal of Controlled Release 120, 169-177.  http://www.sciencedirect.com/science/article/pii/S0168365907002362

Yildiz N, Tuna Ş, Döker O and Çalimli A (2007) Micronization of salicylic acid and taxol (paclitaxel) by rapid expansion of supercritical fluids (RESS). The Journal of Supercritical Fluids 41, 440-451.  http://www.sciencedirect.com/science/article/pii/S0896844606003998

Yonemoto H, Ogino S, Nakashima MN, Wada M and Nakashima K (2007) Determination of paclitaxel in human and rat blood samples after administration of low dose paclitaxel by HPLC-UV detection. Biomedical Chromatography 21, 310-317.  http://dx.doi.org/10.1002/bmc.759

Zenk MH and Juenger M (2007) Evolution and current status of the phytochemistry of nitrogenous compounds. Phytochemistry 68, 2757-2772.  http://www.sciencedirect.com/science/article/pii/S0031942207004633

Zhang C and Fevereiro PS (2007) The effect of heat shock on paclitaxel production in Taxus yunnanensis cell suspension cultures: Role of abscisic acid pretreatment. Biotechnology and Bioengineering 96, 506-514.  http://dx.doi.org/10.1002/bit.21122

Zhao Y, Yang X-B, Wang Q-F, Nan P-J, Jin Y and Zhang S-Y (2007) Determination of enantiomeric excess for 2,3-dihydroxy-3-phenylpropionate compounds by capillary electrophoresis using hydroxypropyl-β-cyclodextrin as chiral selector. Chirality 19, 380-385.  http://dx.doi.org/10.1002/chir.20393

Ziemons E, Mbakop NW, Rozet E, Lejeune R, Angenot L, Thunus L and Hubert P (2007) Optimisation of SFE method on-line coupled to FT-IR spectroscopy for the real-time monitoring of the extraction of tagitinin C in T. diversifolia. The Journal of Supercritical Fluids 40, 368-375.  http://www.sciencedirect.com/science/article/pii/S0896844606001938

(2006) Small-Cell Lung Cancer. In ‘Wiley Handbook of Current and Emerging Drug Therapies’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470041000.cedt016

Ahmad I, Aqil F, Ahmad F and Owais M (2006) Herbal Medicines: Prospects and Constraints. In ‘Modern Phytomedicine’ (Ed.^(Eds  pp. 59-77. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527609987.ch3

André N and Meille C (2006) Taxanes in paediatric oncology: And now? Cancer Treatment Reviews 32, 65-73.  http://www.sciencedirect.com/science/article/pii/S0305737206000107

Bergstralh DT and Ting JPY (2006) Microtubule stabilizing agents: Their molecular signaling consequences and the potential for enhancement by drug combination. Cancer Treatment Reviews 32, 166-179.  http://www.sciencedirect.com/science/article/pii/S0305737206000119

Bestoso F, Ottaggio L, et al. (2006) In vitro cell cultures obtained from different explants of Corylus avellana produce Taxol and taxanes. BMC Biotechnol 6, 45.

Blagg BSJ and Kerr TD (2006) Hsp90 inhibitors: Small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation. Medicinal Research Reviews 26, 310-338.  http://dx.doi.org/10.1002/med.20052

Braun L (2006) Herbal Medicines and Interactions with Conventional Medicines Used to Manage Diabetes. In ‘Complementary Therapies and the Management of Diabetes and Vascular Disease’ (Ed.^(Eds  pp. 211-232. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470057438.ch9

Breitmaier E (2006) Diterpenes. In ‘Terpenes’ (Ed.^(Eds  pp. 52-81. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527609949.ch4

Brück TB and Kerr RG (2006) Purification and kinetic properties of elisabethatriene synthase from the coral Pseudopterogorgia elisabethae. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 143, 269-278.  http://www.sciencedirect.com/science/article/pii/S1096495905002770

Buss AD, Cox B and Waigh RD (2006) Therapeutic Compounds in Nature as Leads for New Pharmaceuticals. In ‘Encyclopedia of Molecular Cell Biology and Molecular Medicine’ (Ed.^(Eds  pp. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/3527600906.mcb.200500072

Cao C-M, Zhang M-L, Wang Y-F, Shi Q-W, Yamada T and Kiyota H (2006) Two New Taxanes from the Needles and Branches Bark of Taxus cuspidata. Chemistry & Biodiversity 3, 1153-1161.  http://dx.doi.org/10.1002/cbdv.200690117

DeJong JM, Liu Y, Bollon AP, Long RM, Jennewein S, Williams D and Croteau RB (2006) Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae. Biotechnology and Bioengineering 93, 212-224.  http://dx.doi.org/10.1002/bit.20694

Dong Y and Feng S-S (2006) Nanoparticles of poly(D,L-lactide)/methoxy poly(ethylene glycol)-poly(D,L-lactide) blends for controlled release of paclitaxel. Journal of Biomedical Materials Research Part A 78A, 12-19.  http://dx.doi.org/10.1002/jbm.a.30684

Duff KJ (2006) Gas and Liquid Chromatography, Column Selection for, in Drug Analysis. In ‘Encyclopedia of Analytical Chemistry’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470027318.a1909

Fan T-P, Yeh J-C, Leung KW, Yue PYK and Wong RNS (2006) Angiogenesis: from plants to blood vessels. Trends in Pharmacological Sciences 27, 297-309.  http://www.sciencedirect.com/science/article/pii/S016561470600109X

Fett-Neto AG, Aoyagi H, Tanaka H and DiCosmo F (2006) Antitumor Agents: Taxol and Taxanes—Production by Yew Cell Culture. In ‘Encyclopedia of Molecular Cell Biology and Molecular Medicine’ (Ed.^(Eds  pp. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/3527600906.mcb.200300127

Fowler MW (2006) Plants, medicines and man. Journal of the Science of Food and Agriculture 86, 1797-1804.  http://dx.doi.org/10.1002/jsfa.2598

Gabellini C, Pucci B, Valdivieso P, D’Andrilli G, Tafani M, De Luca A and Masciullo V (2006) p27kip1 overexpression promotes paclitaxel-induced apoptosis in pRb-defective SaOs-2 cells. Journal of Cellular Biochemistry 98, 1645-1652.  http://dx.doi.org/10.1002/jcb.20900

Gao S, Zhang Z-P, Edinboro LE, Ngoka LC and Karnes HT (2006) The effect of alkylamine additives on the sensitivity of detection for paclitaxel and docetaxel and analysis in plasma of paclitaxel by liquid chromatography–tandem mass spectrometry. Biomedical Chromatography 20, 683-695.  http://dx.doi.org/10.1002/bmc.582

Gréen H, Rosenberg P, Söderkvist P, Horvath G and Peterson C (2006) β-Tubulin mutations in ovarian cancer using single strand conformation analysis-risk of false positive results from paraffin embedded tissues. Cancer Letters 236, 148-154.  http://www.sciencedirect.com/science/article/pii/S0304383505005069

Gréen H, Vretenbrant K, Norlander B and Peterson C (2006) Measurement of paclitaxel and its metabolites in human plasma using liquid chromatography/ion trap mass spectrometry with a sonic spray ionization interface. Rapid Communications in Mass Spectrometry 20, 2183-2189.  http://dx.doi.org/10.1002/rcm.2567

Hamada H, Ishihara K, Masuoka N, Mikuni K and Nakajima N (2006) Enhancement of water-solubility and bioactivity of paclitaxel using modified cyclodextrins. Journal of Bioscience and Bioengineering 102, 369-371.  http://www.sciencedirect.com/science/article/pii/S1389172306706788

Han L-m, Guo J, Zhang L-j, Wang Q-s and Fang X-l (2006) Pharmacokinetics and biodistribution of polymeric micelles of paclitaxel with Pluronic P1231. Acta Pharmacologica Sinica 27, 747-753.  http://dx.doi.org/10.1111/j.1745-7254.2006.00340.x

Harlow BA, Marshall JD and Robinson AP (2006) A multi-species comparison of {delta}13C from whole wood, extractive-free wood and holocellulose. Tree Physiol 26, 767-774.  http://treephys.oxfordjournals.org/cgi/content/abstract/26/6/767

Heinz G F (2006) Combinatorial biosynthesis—Potential and problems. Journal of Biotechnology 124, 242-257.  http://www.sciencedirect.com/science/article/pii/S0168165605007558

HemaIswarya S and Doble M (2006) Potential synergism of natural products in the treatment of cancer. Phytotherapy Research 20, 239-249.  http://dx.doi.org/10.1002/ptr.1841

Hennenfent KL and Govindan R (2006) Novel formulations of taxanes: a review. Old wine in a new bottle? Ann. Onc. 17, 735-749.  http://annonc.oxfordjournals.org/cgi/content/abstract/17/5/735

Iszkuło G and Boratyński A (2006) Analysis of the relationship between photosynthetic photon flux density and natural Taxus baccata seedlings occurrence. Acta Oecologica 29, 78-84.  http://www.sciencedirect.com/science/article/pii/S1146609X05000895

Ivors K, Garbelotto M, Vries IDE, Ruyter-Spira C, Hekkert BT, Rosenzweig N and Bonants P (2006) Microsatellite markers identify three lineages of Phytophthora ramorum in US nurseries, yet single lineages in US forest and European nursery populations. Molecular Ecology 15, 1493-1505.  http://dx.doi.org/10.1111/j.1365-294X.2006.02864.x

Jagetia GC and Baliga MS (2006) Evaluation of anticancer activity of the alkaloid fraction of Alstonia scholaris (Sapthaparna) in vitro and in vivo. Phytotherapy Research 20, 103-109.  http://dx.doi.org/10.1002/ptr.1810

Jeon SI, Mun S and Kim J-H (2006) Optimal temperature control in fractional precipitation for paclitaxel pre-purification. Process Biochemistry 41, 276-280.  http://www.sciencedirect.com/science/article/pii/S1359511305003223

Ji Y, Bi JN, Yan B and Zhu XD (2006) [Taxol-producing fungi: a new approach to industrial production of taxol]. Sheng Wu Gong Cheng Xue Bao 22, 1-6.

Ji Y, Bi J-N, Yan B and Zhu X-D (2006) Taxol-producing Fungi: A New Approach to Industrial Production of Taxol. Chinese Journal of Biotechnology 22, 1-6.  http://www.sciencedirect.com/science/article/pii/S1872207506600010

Julsing MK, Koulman A, Woerdenbag HJ, Quax WJ and Kayser O (2006) Combinatorial biosynthesis of medicinal plant secondary metabolites. Biomolecular Engineering 23, 265-279.  http://www.sciencedirect.com/science/article/pii/S1389034406000906

Karliga B, Schilling JK, Kingston DGI, Bane S, Ravindra R and Talinli N (2006) Synthesis and Biological Evaluation of N-(Arylsulfanyl)carbonyl Analogues of Paclitaxel (Taxol). Chemistry & Biodiversity 3, 396-404.  http://dx.doi.org/10.1002/cbdv.200690043

Keeling CI and Bohlmann J (2006) Genes, enzymes and chemicals of terpenoid diversity in the constitutive and induced defence of conifers against insects and pathogens*. New Phytologist 170, 657-675.  http://dx.doi.org/10.1111/j.1469-8137.2006.01716.x

Khosroushahi AY, Valizadeh M, Ghasempour A, Khosrowshahli M, Naghdibadi H, Dadpour MR and Omidi Y (2006) Improved Taxol production by combination of inducing factors in suspension cell culture of Taxus baccata. Cell Biology International 30, 262-269.  http://www.sciencedirect.com/science/article/pii/S1065699505002878

Lai C-T, Ehleringer JR, Bond BJ and Paw U KT (2006) Contributions of evaporation, isotopic non-steady state transpiration and atmospheric mixing on the δ18O of water vapour in Pacific Northwest coniferous forests. Plant, Cell & Environment 29, 77-94.  http://dx.doi.org/10.1111/j.1365-3040.2005.01402.x

Link TE, Flerchinger GN, Unsworth M and Marks D (2006) Water Relations of an Old-Growth Douglas Fir Stand. In ‘Climate and Hydrology in Mountain Areas’ (Ed.^(Eds  pp. 147-159. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/0470858249.ch11

Liu SQ (2006) Vascular Regenerative Engineering. In ‘Bioregenerative Engineering: Principles and Applications’ (Ed.^(Eds  pp. 659-735. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470116869.ch15

Merten J, Hennig A, Schwab P, Fröhlich R, Tokalov SV, Gutzeit HO and Metz P (2006) A Concise Sultone Route to Highly Oxygenated 1,10-seco-Eudesmanolides – Enantioselective Total Synthesis of the Antileukemic Sesquiterpene Lactones(–)-Eriolanin and (–)-Eriolangin. European Journal of Organic Chemistry 2006, 1144-1161.  http://dx.doi.org/10.1002/ejoc.200500739

Mielke S, Sparreboom A and Mross K (2006) Peripheral neuropathy: A persisting challenge in paclitaxel-based regimes. European Journal of Cancer 42, 24-30.  http://www.sciencedirect.com/science/article/pii/S0959804905008439

Oh E, Hansen EM and Sniezko RA (2006) Port-Orford-cedar resistant to Phytophthora lateralis

Des Chamaecyparis de Lawson résistants ŕ Phytophthora lateralis

Resistenz von Chamaecyparis lawsoniana gegen Phytophthora lateralis. Forest Pathology 36, 385-394.  http://dx.doi.org/10.1111/j.1439-0329.2006.00474.x

Pastorino L, Caneva Soumetz F, Giacomini M and Ruggiero C (2006) Development of a piezoelectric immunosensor for the measurement of paclitaxel. Journal of Immunological Methods 313, 191-198.  http://www.sciencedirect.com/science/article/pii/S0022175906001335

Patents Court (2006) ANGIOTECH PHARMACEUTICALS INC’S PATENT (APPLICATION FOR REVOCATION BY CONOR MEDSYSTEMS INC). R.P.C. 123, 665-697.  http://rpc.oxfordjournals.org/cgi/content/abstract/123/20/665

Pflieger C, Becker M, Beckmann D, Frense D, Hensel J, Hornbogen T, Lauckner G, Lisicki D and Zocher R (2006) Membrangestützte Extraktion bei enzymatischen Reaktionen in Anwesenheit organischer Lösungsmittel. Chemie Ingenieur Technik 78, 120-123.  http://dx.doi.org/10.1002/cite.200500081

Powers R and Siegel MM (2006) 5 - Applications of Nuclear Magnetic Resonance and Mass Spectrometry to Anticancer Drug Discovery. In ‘Novel Anticancer Agents’ (Ed.^(Eds Alex AA and John KB) pp. 107-XIV. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780120885619500065

Punit R and Jonathan H (2006) Drug eluting stents. Oxford Handbook of Cardiology 1, med-9780198525974-div1-107-.  http://ohcardio.oxfordmedicine.com

Scripture CD, Figg WD and Sparreboom A (2006) Peripheral neuropathy induced by paclitaxel: recent insights and future perspectives. Curr Neuropharmacol 4, 165-72.

Senthilnathan P, Padmavathi R, Magesh V and Sakthisekaran D (2006) Modulation of TCA cycle enzymes and electron transport chain systems in experimental lung cancer. Life Sciences 78, 1010-1014.  http://www.sciencedirect.com/science/article/pii/S0024320505007782

Senthilnathan P, Padmavathi R, Magesh V and Sakthisekaran D (2006) Chemotherapeutic efficacy of paclitaxel in combination with Withania somnifera on benzo(a)pyrene-induced experimental lung cancer. Cancer Science 97, 658-664.  http://dx.doi.org/10.1111/j.1349-7006.2006.00224.x

Sharp S and Workman P (2006) Inhibitors of the HSP90 Molecular Chaperone: Current Status. In ‘Advances in Cancer Research’ (Ed.^(Eds George FVW and George K) pp. 323-348. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0065230X0695009X

Sivakumar G (2006) Bioreactor technology: A novel industrial tool for high-tech production of bioactive molecules and biopharmaceuticals from plant roots. Biotechnology Journal 1, 1419-1427.  http://dx.doi.org/10.1002/biot.200600117

Smith WL and Wheeler WC (2006) Venom Evolution Widespread in Fishes: A Phylogenetic Road Map for the Bioprospecting of Piscine Venoms. J. Hered. 97, 206-217.  http://jhered.oxfordjournals.org/cgi/content/abstract/97/3/206

Sneader W (2006) Non-Alkaloidal Plant Products. In ‘Drug Discovery’ (Ed.^(Eds  pp. 106-114. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/0470015535.ch10

Swenson JJ and Waring RH (2006) Modelled photosynthesis predicts woody plant richness at three geographic scales across the north-western United States. Global Ecology and Biogeography 15, 470-485.  http://dx.doi.org/10.1111/j.1466-822X.2006.00242.x

Verheyden H, Ballon P, Bernard V and Saint-Andrieux C (2006) Variations in bark-stripping by red deer Cervus elaphus across Europe. Mammal Review 36, 217-234.  http://dx.doi.org/10.1111/j.1365-2907.2006.00085.x

Vivekanandan K, Swamy MG, Prasad S, Mukherjee R and Burman AC (2006) Identification of isocephalomannine in the presence of cephalomannine isomers and alkali metal ion adducts in a paclitaxel active pharmaceutical ingredient using electrospray tandem mass spectrometry. Rapid Communications in Mass Spectrometry 20, 1731-1735.  http://dx.doi.org/10.1002/rcm.2500

Wang B, Zhang G, Zhu L, Chen L and Zhang Y (2006) Genetic transformation of Echinacea purpurea with Agrobacterium rhizogenes and bioactive ingredient analysis in transformed cultures. Colloids and Surfaces B: Biointerfaces 53, 101-104.  http://www.sciencedirect.com/science/article/pii/S0927776506002530

Watkins EB, Chittiboyina AG and Avery MA (2006) Recent Developments in the Syntheses of the Epothilones and Related Analogues. European Journal of Organic Chemistry 2006, 4071-4084.  http://dx.doi.org/10.1002/ejoc.200600149

Win KY and Feng S-S (2006) In vitro and in vivo studies on vitamin E TPGS-emulsified poly(d,l-lactic-co-glycolic acid) nanoparticles for paclitaxel formulation. Biomaterials 27, 2285-2291.  http://www.sciencedirect.com/science/article/pii/S0142961205010355

Wisdom MJ, Vavra M, Boyd JM, Hemstrom MA, Ager AA and Johnson BK (2006) Understanding Ungulate Herbivory—Episodic Disturbance Effects on Vegetation Dynamics: Knowledge Gaps and Management Needs. Wildlife Society Bulletin 34, 283-292.  http://dx.doi.org/10.2193/0091-7648(2006)34[283:UUHDEO]2.0.CO;2

Wunderlich S, Zähres M, Jo B-W and Hess M (2006) Paclitaxel-Warfarin Interaction in Solution. Macromolecular Symposia 242, 71-79.  http://dx.doi.org/10.1002/masy.200651012

Xu F, Tao W, Cheng L and Guo L (2006) Strain improvement and optimization of the media of taxol-producing fungus Fusarium maire. Biochemical Engineering Journal 31, 67-73.  http://www.sciencedirect.com/science/article/pii/S1369703X06001331

Zard SZ (2006) Pierre Potier (1934–2006). Angewandte Chemie 118, 2558-2559.  http://dx.doi.org/10.1002/ange.200600811

Zhao P-J, Li G-H and Shen Y-M (2006) New Chemical Constituents from the Endophyte Streptomyces Species LR4612 Cultivated on Maytenus hookeri. Chemistry & Biodiversity 3, 337-342.  http://dx.doi.org/10.1002/cbdv.200690036

Zu Y, Fu Y, Li S, Sun R, Li Q and Schwarz G (2006) Rapid separation of four main taxoids in Taxus species by a combined LLP-SPE-HPLC (PAD) procedure. Journal of Separation Science 29, 1237-1244.  http://dx.doi.org/10.1002/jssc.200500483

Zwerdling T, Krailo M, et al. (2006) Phase II investigation of docetaxel in pediatric patients with recurrent solid tumors. Cancer 106, 1821-1828.  http://dx.doi.org/10.1002/cncr.21779

(2005) Yew Trees. In ‘Van Nostrand’s Scientific Encyclopedia’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471743984.vse7612

(2005) Titelbild: Pharmazie in unserer Zeit 2/2005. Pharmazie in unserer Zeit 34, 89-89.  http://dx.doi.org/10.1002/pauz.200590033

(2005) Infokasten: Die Eibe. Pharmazie in unserer Zeit 34, 109-109.  http://dx.doi.org/10.1002/pauz.200590018

(2005) Glossar: Pharmazie in unserer Zeit 2/2005. Pharmazie in unserer Zeit 34, 97-97.  http://dx.doi.org/10.1002/pauz.200590039

(2005) Index. In ‘Integrated Strategies for Drug Discovery Using Mass Spectrometry’ (Ed.^(Eds  pp. 543-550. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471721034.index

(2005) Fragebogen zur Pharmuz “TaxaneE”. Pharmazie in unserer Zeit 34, 161-162.  http://dx.doi.org/10.1002/pauz.200590022

(2005) Infokasten: Chronologie der Taxane. Pharmazie in unserer Zeit 34, 151-151.  http://dx.doi.org/10.1002/pauz.200590019

Ann P S (2005) Yew. In ‘Encyclopedia of Toxicology (Second Edition)’ (Ed.^(Eds Editor-in-Chief:   Philip W) pp. 475-476. (Elsevier: New York). http://www.sciencedirect.com/science/article/pii/B0123694000010231

Armirotti A, Benatti U, Miele M and Damonte G (2005) Matrix-assisted laser desorption/ionization mass spectrometry of taxanes. Rapid Communications in Mass Spectrometry 19, 3531-3538.  http://dx.doi.org/10.1002/rcm.2227

Asai Y, Takaori K, Yamamoto T and Ogawa T (2005) Protein-bound polysaccharide isolated from basidiomycetes inhibits endotoxin-induced activation by blocking lipopolysaccharide-binding protein and CD14 functions. FEMS Immunology and Medical Microbiology 43, 91-98.  http://www.sciencedirect.com/science/article/pii/S0928824404001622

Barrett SV and Cassidy J (2005) Conventional Chemotherapeutics. In ‘The Cancer Handbook’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470025079.chap84a.pub2

Barth J (2005) Applikation taxanhaltiger Arzneimittel: Beachtenswerte Besonderheiten. Pharmazie in unserer Zeit 34, 152-158.  http://dx.doi.org/10.1002/pauz.200400116

Bentebibel S, Moyano E, Palazón J, Cusidó RM, Bonfill M, Eibl R and Pińol MT (2005) Effects of immobilization by entrapment in alginate and scale-up on paclitaxel and baccatin III production in cell suspension cultures of Taxus baccata. Biotechnology and Bioengineering 89, 647-655.  http://dx.doi.org/10.1002/bit.20321

Bouvier E, Schmidt F and Monneret C (2005) Prodrogues glucuronylées du paclitaxel (Taxol®) activables au niveau des tumeurs. Annales Pharmaceutiques Françaises 63, 53-62.  http://www.sciencedirect.com/science/article/pii/S0003450905822515

Choi J-S and Shin S-C (2005) Enhanced paclitaxel bioavailability after oral coadministration of paclitaxel prodrug with naringin to rats. International Journal of Pharmaceutics 292, 149-156.  http://www.sciencedirect.com/science/article/pii/S0378517304007264

Duan B, Lu Y, Yin C, Junttila O and Li C (2005) Physiological responses to drought and shade in two contrasting Picea asperata populations. Physiologia Plantarum 124, 476-484.  http://dx.doi.org/10.1111/j.1399-3054.2005.00535.x

Feldweg AM, Lee C-W, Matulonis UA and Castells M (2005) Rapid desensitization for hypersensitivity reactions to paclitaxel and docetaxel: a new standard protocol used in 77 successful treatments. Gynecologic Oncology 96, 824-829.  http://www.sciencedirect.com/science/article/pii/S009082580400976X

Fortman JL and Sherman DH (2005) Utilizing the Power of Microbial Genetics to Bridge the Gap Between the Promise and the Application of Marine Natural Products. ChemBioChem 6, 960-978.  http://dx.doi.org/10.1002/cbic.200400428

Franceschi VR, Krokene P, Christiansen E and Krekling T (2005) Anatomical and chemical defenses of conifer bark against bark beetles and other pests. New Phytologist 167, 353-376.  http://dx.doi.org/10.1111/j.1469-8137.2005.01436.x

Gao X-X, Zhou H, Xu D-Y, Yu C-H, Chen Y-Q and Qu L-H (2005) High diversity of endophytic fungi from the pharmaceutical plant, Heterosmilax japonica Kunth revealed by cultivation-independent approach. FEMS Microbiology Letters 249, 255-266.  http://dx.doi.org/10.1016/j.femsle.2005.06.017

Geney R, Sun L, Pera P, Bernacki RJ, Xia S, Horwitz SB, Simmerling CL and Ojima I (2005) Use of the Tubulin Bound Paclitaxel Conformation for Structure-Based Rational Drug Design. Chemistry &amp; Biology 12, 339-348.  http://www.sciencedirect.com/science/article/pii/S1074552105000244

Gilbert JR, Lewer P, Duebelbeis DO and Carr AW (2005) The Central Role of Mass Spectrometry in Natural Products Discovery. In ‘Integrated Strategies for Drug Discovery Using Mass Spectrometry’ (Ed.^(Eds  pp. 149-188. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471721034.ch6

Gomes Vancini R and Benchimol M (2005) Appearance of virus-like particles in Tritrichomonas foetus after drug treatment. Tissue and Cell 37, 317-323.  http://www.sciencedirect.com/science/article/pii/S004081660500042X

Hess M, Jo BW, Wermeckes B, Dehne S, Sohn JS, Wunderlich S and Zähres M (2005) Properties of a Water-Soluble Paclitaxel Conjugate in Aqueous Solution and its Interaction with Serum Albumin. Macromolecular Symposia 231, 28-46.  http://dx.doi.org/10.1002/masy.200590023

Hu MY, Zhong GH, Sun ZT, Sh G, Liu HM and Liu XQ (2005) Insecticidal activities of secondary metabolites of endophytic Pencillium sp. in Derris elliptica Benth. Journal of Applied Entomology 129, 413-417.  http://dx.doi.org/10.1111/j.1439-0418.2005.00988.x

Jagetia GC and Baliga MS (2005) The effect of seasonal variation on the antineoplastic activity of Alstonia scholaris R. Br. in HeLa cells. Journal of Ethnopharmacology 96, 37-42.  http://www.sciencedirect.com/science/article/pii/S0378874104003964

Jennewein S, Park H, DeJong JM, Long RM, Bollon AP and Croteau RB (2005) Coexpression in yeast of Taxus cytochrome P450 reductase with cytochrome P450 oxygenases involved in Taxol biosynthesis. Biotechnology and Bioengineering 89, 588-598.  http://dx.doi.org/10.1002/bit.20390

Jin Q, Williams DC, Hezari M, Croteau R and Coates RM (2005) Stereochemistry of the macrocyclization and elimination steps in taxadiene biosynthesis through deuterium labeling. J Org Chem 70, 4667-75.

Jones GB (2005) Anticancer Drugs (The History). In ‘Van Nostrand’s Scientific Encyclopedia’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780471743989.vse9799

Kim JS and Jobin C (2005) The flavonoid luteolin prevents lipopolysaccharide-induced NF-κB signalling and gene expression by blocking IκB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells. Immunology 115, 375-387.  http://dx.doi.org/10.1111/j.1365-2567.2005.02156.x

Klvana M, Legros R and Jolicoeur M (2005) In situ extraction strategy affects benzophenanthridine alkaloid production fluxes in suspension cultures of Eschscholtzia californica. Biotechnology and Bioengineering 89, 280-289.  http://dx.doi.org/10.1002/bit.20306

Kumar DSS, Lau CS, Wan JMF, Yang D and Hyde KD (2005) Immunomodulatory compounds from Pestalotiopsis leucothës, an endophytic fungus from Tripterygium wilfordii. Life Sciences 78, 147-156.  http://www.sciencedirect.com/science/article/pii/S0024320505006806

Kummalue T (2005) Molecular mechanism of herbs in human lung cancer cells. J Med Assoc Thai 88, 1725-34.

Leistner E (2005) Die Biologie der Taxane: Arzneimittel aus der Natur. Pharmazie in unserer Zeit 34, 98-103.  http://dx.doi.org/10.1002/pauz.200400108

Lev-Yadun S (2005) Bark. In ‘Van Nostrand’s Scientific Encyclopedia’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780471743989.vse0905.pub2

Liu C, Tamm M, et al. (2005) C-3′-Cyclopropanated Taxol Analogs: Synthesis, Bioassay and Biostructural Analysis. European Journal of Organic Chemistry 2005, 3962-3972.  http://dx.doi.org/10.1002/ejoc.200500243

Long RM and Croteau R (2005) Preliminary assessment of the C13-side chain 2′-hydroxylase involved in Taxol biosynthesis. Biochemical and Biophysical Research Communications 338, 410-417.  http://www.sciencedirect.com/science/article/pii/S0006291X0501853X

Lorusso V and Silvestris N (2005) Systemic chemotherapy for patients with advanced and metastatic bladder cancer: current status and future directions. Ann. Onc. 16, iv85-89.  http://annonc.oxfordjournals.org

Lu KH, Lue KH, Chou MC and Chung JG (2005) Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS). Journal of Orthopaedic Research 23, 988-994.  http://www.sciencedirect.com/science/article/pii/S0736026605000586

Lu KH, Lue KH, Hsia TC, Chou MC, Lin KL and Chung JG (2005) Oral administration of paclitaxel affects the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats. Phytomedicine 12, 577-587.  http://www.sciencedirect.com/science/article/pii/S094471130500067X

Mbewu AD (2005) Introductory Remarks: African Perspective on Natural Products and Molecular Medicine. Annals of the New York Academy of Sciences 1056, xv-xix.  http://dx.doi.org/10.1196/annals.1352.042

Naill MC and Roberts SC (2005) Cell cycle analysis of Taxus suspension cultures at the single cell level as an indicator of culture heterogeneity. Biotechnology and Bioengineering 90, 491-500.  http://dx.doi.org/10.1002/bit.20446

Naill MC and Roberts SC (2005) Flow Cytometric Identification of Paclitaxel-Accumulating Subpopulations. Biotechnology Progress 21, 978-983.  http://dx.doi.org/10.1021/bp049544l

Ng R (2005) Drug Discovery: Small Molecule Drugs. In ‘Drugs’ (Ed.^(Eds  pp. 43-74. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471722804.ch3

Parry TJ, Brosius R, Thyagarajan R, Carter D, Argentieri D, Falotico R and Siekierka J (2005) Drug-eluting stents: Sirolimus and paclitaxel differentially affect cultured cells and injured arteries. European Journal of Pharmacology 524, 19-29.  http://www.sciencedirect.com/science/article/pii/S0014299905009064

Pyo S-H, Song B-K, Ju C-H, Han B-H and Choi H-J (2005) Effects of absorbent treatment on the purification of paclitaxel from cell cultures of Taxus chinensis and yew tree. Process Biochemistry 40, 1113-1117.  http://www.sciencedirect.com/science/article/pii/S0032959204001803

Quinn DI, Creaven PJ and Raghavan D (2005) Chapter 4 - Principles of Chemotherapy for Genitourinary Cancer. In ‘Urologic Oncology’ (Ed.^(Eds Jerome PR, Md, et al.) pp. 51-87. (W.B. Saunders: Philadelphia). http://www.sciencedirect.com/science/article/pii/B9780721600031500071

Requena M-E, Egea-Gilabert C and Candela M-E (2005) Nitric oxide generation during the interaction with Phytophthora capsici of two Capsicum annuum varieties showing different degrees of sensitivity. Physiologia Plantarum 124, 50-60.  http://dx.doi.org/10.1111/j.1399-3054.2005.00485.x

Salgın U, Üstün AS, Mehmetoǧlu Ü and Çalımlı A (2005) Supercritical CO2 extraction of accumulated capsidiol from biotic elicitor-activated Capsicum annuum L fruit tissues. Journal of Chemical Technology & Biotechnology 80, 124-132.  http://dx.doi.org/10.1002/jctb.1114

Shanks JV (2005) Phytochemical engineering: Combining chemical reaction engineering with plant science. AIChE Journal 51, 2-7.  http://dx.doi.org/10.1002/aic.10418

Shi Q-W and Kiyota H (2005) New Natural Taxane Diterpenoids from Taxus Species since 1999. Chemistry & Biodiversity 2, 1597-1623.  http://dx.doi.org/10.1002/cbdv.200590131

Song L, Prey JD, Xue J, Kanter P, Manzotti C, Bombardelli E, Morazzoni P and Pendyala L (2005) Pharmacokinetic measurements of IDN 5390 using electrospray ionization tandem mass spectrometry: structure characterization and quantification in dog plasma. Rapid Communications in Mass Spectrometry 19, 3617-3625.  http://dx.doi.org/10.1002/rcm.2235

Sonnenschein M and Plescher A (2005) Inkulturnahme und kontrollierter Anbau von Weißdorn (Crataegus spp.): Industrielle Gewinnung der Arzneidroge. Pharmazie in unserer Zeit 34, 42-47.  http://dx.doi.org/10.1002/pauz.200400103

Soto J, Sainz C, Cos S and Gonzalez Larnuńo D (2005) - Non linear effects of harmful agents: Application of a irradiation and taxol on human cancer cells in vitro. In ‘Recent Advances in Multidisciplinary Applied Physics’ (Ed.^(Eds Méndez-Vilas A) pp. 737-744. (Elsevier Science Ltd: Oxford). http://www.sciencedirect.com/science/article/pii/B9780080446486501129

Spainhour CB (2005) Natural Products. In ‘Drug Discovery Handbook’ (Ed.^(Eds  pp. 11-72. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471728780.ch1

Spiteller P and von Nussbaum F (2005) Biosynthesis of β-Amino Acids. In ‘Highlights in Bioorganic Chemistry’ (Ed.^(Eds  pp. 90-106. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/3527603727.ch1f

Straubinger RM and Balasubramanian SV (2005) Preparation and Characterization of Taxane-Containing Liposomes. In ‘Methods in Enzymology’ (Ed.^(Eds Nejat D) pp. 97-117. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0076687905910057

Takeda K and Akira S (2005) Toll-like receptors in innate immunity. Int. Immunol. 17, 1-14.  http://intimm.oxfordjournals.org/cgi/content/abstract/17/1/1

Wang JW and Wu JY (2005) Nitric Oxide is Involved in Methyl Jasmonate-induced Defense Responses and Secondary Metabolism Activities of Taxus Cells. Plant Cell Physiol. 46, 923-930.  http://pcp.oxfordjournals.org/cgi/content/abstract/46/6/923

Xu Q-m, Cheng J-s, Ge Z-q and Yuan Y-j (2005) Abnormal mitosis versus apoptosis of Taxus cuspidata induced by oleic acid in two-liquid-phase suspension cultures. Enzyme and Microbial Technology 37, 76-81.  http://www.sciencedirect.com/science/article/pii/S0141022905000748

Yang C-F, Sun S-G and Guo Y-H (2005) Resource limitation and pollen source (self and outcross) affecting seed production in two louseworts, Pedicularis siphonantha and P. longiflora (Orobanchaceae). Botanical Journal of the Linnean Society 147, 83-89.  http://dx.doi.org/10.1111/j.1095-8339.2005.00363.x

Yarrow JC, Totsukawa G, Charras GT and Mitchison TJ (2005) Screening for Cell Migration Inhibitors via Automated Microscopy Reveals a Rho-Kinase Inhibitor. Chemistry &amp; Biology 12, 385-395.  http://www.sciencedirect.com/science/article/pii/S1074552105000384

Ye M and Guo D-a (2005) Investigations of taxoids by electrospray and atmospheric pressure chemical ionization with tandem mass spectrometry. Rapid Communications in Mass Spectrometry 19, 818-824.  http://dx.doi.org/10.1002/rcm.1839

Zhang JA, Anyarambhatla G, Ma L, Ugwu S, Xuan T, Sardone T and Ahmad I (2005) Development and characterization of a novel Cremophor® EL free liposome-based paclitaxel (LEP-ETU) formulation. European Journal of Pharmaceutics and Biopharmaceutics 59, 177-187.  http://www.sciencedirect.com/science/article/pii/S0939641104001973

(2004) Taxol (Paclitaxel). In ‘Encyclopedic Dictionary of Genetics, Genomics and Proteomics’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471684228.egp12365

Ahn HJ, Kim YS, Kim J-U, Han SM, Shin JW and Yang HO (2004) Mechanism of taxol-induced apoptosis in human SKOV3 ovarian carcinoma cells. Journal of Cellular Biochemistry 91, 1043-1052.  http://dx.doi.org/10.1002/jcb.20006

Amanullah A, Buckland BC and Nienow AW (2004) Mixing in the Fermentation and Cell Culture Industries. In ‘Handbook of Industrial Mixing’ (Ed.^(Eds  pp. 1071-1170. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471451452.ch18

Besumbes Ó, Sauret-Güeto S, Phillips MA, Imperial S, Rodríguez-Concepción M and Boronat A (2004) Metabolic engineering of isoprenoid biosynthesis in Arabidopsis for the production of taxadiene, the first committed precursor of Taxol. Biotechnology and Bioengineering 88, 168-175.  http://dx.doi.org/10.1002/bit.20237

Bolsover SR, Hyams JS, Shephard EA, White HA and Wiedemann CG (2004) Glossary. In ‘Cell Biology’ (Ed.^(Eds  pp. 441-500. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/047146158X.gloss

Borghaei H, Millenson M, Schilder R, Alden M, Rogatko A, Wang H, Padavic-Shaller K and Smith MR (2004) Phase II study of paclitaxel and estramustine in patients with recurrent and refractory non-Hodgkin lymphoma. Cancer 101, 2034-2041.  http://dx.doi.org/10.1002/cncr.20616

Bruňáková K, Babincová Z and Čellárová E (2004) Selection of Callus Cultures of Taxus baccata L. as a Potential Source of Paclitaxel Production. Engineering in Life Sciences 4, 465-469.  http://dx.doi.org/10.1002/elsc.200420050

Buey RM, Dı́az JF, Andreu JM, O’Brate A, Giannakakou P, Nicolaou KC, Sasmal PK, Ritzén A and Namoto K (2004) Interaction of Epothilone Analogs with the Paclitaxel Binding Site: Relationship between Binding Affinity, Microtubule Stabilization, and Cytotoxicity. Chemistry &amp; Biology 11, 225-236.  http://www.sciencedirect.com/science/article/pii/S1074552104000250

Chau M, Jennewein S, Walker K and Croteau R (2004) Taxol Biosynthesis: Molecular Cloning and Characterization of a Cytochrome P450 Taxoid 7β-Hydroxylase. Chemistry &amp; Biology 11, 663-672.  http://www.sciencedirect.com/science/article/pii/S1074552104001115

Chen J, Song B, Rudnicki M, Moeur M, Bible K, North M, Shaw DC, Franklin JF and Braun DM (2004) Spatial relationship of biomass and species distribution in an old-growth Pseudotsuga-Tsuga forest. Forest science. 50, 364-375.

Choi J-S, Choi H-K and Shin S-C (2004) Enhanced bioavailability of paclitaxel after oral coadministration with flavone in rats. International Journal of Pharmaceutics 275, 165-170.  http://www.sciencedirect.com/science/article/pii/S0378517304000675

Choi J-S and Jo B-W (2004) Enhanced paclitaxel bioavailability after oral administration of pegylated paclitaxel prodrug for oral delivery in rats. International Journal of Pharmaceutics 280, 221-227.  http://www.sciencedirect.com/science/article/pii/S0378517304003059

Choi J-S, Jo B-W and Kim Y-C (2004) Enhanced paclitaxel bioavailability after oral administration of paclitaxel or prodrug to rats pretreated with quercetin. European Journal of Pharmaceutics and Biopharmaceutics 57, 313-318.  http://www.sciencedirect.com/science/article/pii/S0939641103002133

Dobesh PP, Stacy ZA, Ansara AJ and Enders JM (2004) Drug-Eluting Stents: A Mechanical and Pharmacologic Approach to Coronary Artery Disease. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 24, 1554-1577.  http://dx.doi.org/10.1592/phco.24.16.1554.50955

Dong Y and Feng S-S (2004) Methoxy poly(ethylene glycol)-poly(lactide) (MPEG-PLA) nanoparticles for controlled delivery of anticancer drugs. Biomaterials 25, 2843-2849.  http://www.sciencedirect.com/science/article/pii/S014296120300797X

Eicher T, Hauptmann S and Speicher A (2004) Four-Membered Heterocycles. In ‘The Chemistry of Heterocycles’ (Ed.^(Eds  pp. 38-51. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/352760183X.ch4

Flatters SJL and Bennett GJ (2004) Ethosuximide reverses paclitaxel- and vincristine-induced painful peripheral neuropathy. Pain 109, 150-161.  http://www.sciencedirect.com/science/article/pii/S0304395904000636

Garber K (2004) Improved Paclitaxel Formulation Hints at New Chemotherapy Approach. J Natl Cancer Inst 96, 90-91.  http://jnci.oxfordjournals.org

Giannoni P, Zambotti A, Pagano A, Cancedda R and Dozin B (2004) Differentiation-dependent activation of the extracellular fatty acid binding protein (Ex-FABP) gene during chondrogenesis. Journal of Cellular Physiology 198, 144-154.  http://dx.doi.org/10.1002/jcp.10405

Halkin A and Stone GW (2004) Polymer-Based Paclitaxel-Eluting Stents in Percutaneous Coronary Intervention. Journal of Interventional Cardiology 17, 271-282.  http://dx.doi.org/10.1111/j.1540-8183.2004.04040.x

Hanson RL, Kant J and Patel RN (2004) Conversion of 7-deoxy-10-deacetylbaccatin-III into 6-α-hydroxy-7-deoxy-10-deacetylbaccatin-III by Nocardioides luteus. Biotechnology and Applied Biochemistry 39, 209-214.  http://dx.doi.org/10.1042/BA20030093

Hsu S, Singh B and Schuster G (2004) Induction of apoptosis in oral cancer cells: agents and mechanisms for potential therapy and prevention. Oral Oncology 40, 461-473.  http://www.sciencedirect.com/science/article/pii/S1368837503002203

Hudgins JW, Christiansen E and Franceschi VR (2004) Induction of anatomically based defense responses in stems of diverse conifers by methyl jasmonate: a phylogenetic perspective. Tree Physiol 24, 251-264.  http://treephys.oxfordjournals.org/cgi/content/abstract/24/3/251

J.H K (2004) Prepurification of paclitaxel by micelle and precipitation. Process Biochemistry 39, 1567-1571.  http://www.sciencedirect.com/science/article/pii/S0032959203002899

Jennewein S, Long RM, Williams RM and Croteau R (2004) Cytochrome P450 Taxadiene 5α-Hydroxylase, a Mechanistically Unusual Monooxygenase Catalyzing the First Oxygenation Step of Taxol Biosynthesis. Chemistry &amp; Biology 11, 379-387.  http://www.sciencedirect.com/science/article/pii/S1074552104000559

Kai G, Miao Z, et al. (2004) Molecular cloning and characterization of a taxadienol acetyl transferase cDNA from Taxus x media. Plant Science 167, 759-764.  http://www.sciencedirect.com/science/article/pii/S0168945204002109

Khersonsky SM and Chang Y-T (2004) Strategies for Facilitated Forward Chemical Genetics. ChemBioChem 5, 903-908.  http://dx.doi.org/10.1002/cbic.200400047

Kim BJ, Gibson DM and Shuler ML (2004) Effect of Subculture and Elicitation on Instability of Taxol Production in Taxus sp. Suspension Cultures. Biotechnology Progress 20, 1666-1673.  http://dx.doi.org/10.1021/bp034274c

Krouglova T, Vercammen J and Engelborghs Y (2004) Correct Diffusion Coefficients of Proteins in Fluorescence Correlation Spectroscopy. Application to Tubulin Oligomers Induced by Mg2+ and Paclitaxel. Biophysical Journal 87, 2635-2646.  http://www.sciencedirect.com/science/article/pii/S0006349504737340

Kwit C, Horvitz CC and Platt WJ (2004) Conserving Slow-Growing, Long-Lived Tree Species: Input from the Demography of a Rare Understory Conifer, Taxus floridana

Conservación de Especies Arbóreas de Crecimiento Lento y Longevas: Insumos de la Demografía de una Conífera de Sotobosque Rara, Taxus floridana. Conservation Biology 18, 432-443.  http://dx.doi.org/10.1111/j.1523-1739.2004.00567.x

Lara PN, Meyers FJ, Law LY, Dawson NA, Houston J, Lauder I and Edelman MJ (2004) Platinum-free combination chemotherapy in patients with advanced or metastatic transitional cell carcinoma. Cancer 100, 82-88.  http://dx.doi.org/10.1002/cncr.11866

Luo J and He G-Y (2004) Optimization of elicitors and precursors for paclitaxel production in cell suspension culture of Taxus chinensis in the presence of nutrient feeding. Process Biochemistry 39, 1073-1079.  http://www.sciencedirect.com/science/article/pii/S003295920300219X

Marshall VG and Clayton MR (2004) Biology and phenology of Cecidophyopsis psilaspis (Acari: Eriophyidae) on Pacific yew (Taxaceae). Canadian entomologist. 136, 695-710.

Mercado-Gómez O, Ferrera P and Arias C (2004) Histopathologic changes induced by the microtubule-stabilizing agent Taxol in the rat hippocampus in vivo. Journal of Neuroscience Research 78, 553-562.  http://dx.doi.org/10.1002/jnr.20264

Moore GW, Bond BJ, Jones JA, Phillips N and Meinzer FC (2004) Structural and compositional controls on transpiration in 40- and 450-year-old riparian forests in western Oregon, USA. Tree Physiol 24, 481-491.  http://treephys.oxfordjournals.org/cgi/content/abstract/24/5/481

Naill MC and Roberts SC (2004) Preparation of single cells from aggregated Taxus suspension cultures for population analysis. Biotechnology and Bioengineering 86, 817-826.  http://dx.doi.org/10.1002/bit.20083

Odoux C and Albers A (2004) Additive Effects of TRAIL and Paclitaxel on Cancer Cells: Implications for Advances in Cancer Therapy. In ‘Vitamins &amp; Hormones’ (Ed.^(Eds Gerald L) pp. 385-407. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0083672904670208

Otomo K, Kenmoku H, Oikawa H, König WA, Toshima H, Mitsuhashi W, Yamane H, Sassa T and Toyomasu T (2004) Biological functions of ent- and syn-copalyl diphosphate synthases in rice: key enzymes for the branch point of gibberellin and phytoalexin biosynthesis. The Plant Journal 39, 886-893.  http://dx.doi.org/10.1111/j.1365-313X.2004.02175.x

Poirier VJ, Hershey AE, Burgess KE, Phillips B, Turek MM, Forrest LJ, Beaver L and Vail DM (2004) Efficacy and Toxicity of Paclitaxel (Taxol) for the Treatment of Canine Malignant Tumors. Journal of Veterinary Internal Medicine 18, 219-222.  http://dx.doi.org/10.1111/j.1939-1676.2004.tb00164.x

Pyo S-H, Kim M-S, Cho J-S, Song B-K, Han B-H and Choi H-J (2004) Efficient purification and morphology characterization of paclitaxel from cell cultures of Taxus chinensis. Journal of Chemical Technology & Biotechnology 79, 1162-1168.  http://dx.doi.org/10.1002/jctb.1111

Pyo S-H, Park H-B, Song B-K, Han B-H and Kim J-H (2004) A large-scale purification of paclitaxel from cell cultures of Taxus chinensis. Process Biochemistry 39, 1985-1991.  http://www.sciencedirect.com/science/article/pii/S0032959203003686

Ranade SV, Miller KM, Richard RE, Chan AK, Allen MJ and Helmus MN (2004) Physical characterization of controlled release of paclitaxel from the TAXUS™ Express2™ drug-eluting stent. Journal of Biomedical Materials Research Part A 71A, 625-634.  http://dx.doi.org/10.1002/jbm.a.30188

Reiling KK, Yoshikuni Y, Martin VJJ, Newman J, Bohlmann J and Keasling JD (2004) Mono and diterpene production in Escherichia coli. Biotechnology and Bioengineering 87, 200-212.  http://dx.doi.org/10.1002/bit.20128

Reuben A (2004) Hy’s law. Hepatology 39, 574-578.  http://dx.doi.org/10.1002/hep.20081

Romero-Puertas MC, Perazzolli M, Zago ED and Delledonne M (2004) Nitric oxide signalling functions in plant–pathogen interactions. Cellular Microbiology 6, 795-803.  http://dx.doi.org/10.1111/j.1462-5822.2004.00428.x

Shi Q-w, Ji X, Lesimple A, Sauriol F and Zamir LO (2004) Taxanes with C-5-amino-side chains from the needles of Taxus canadensis. Phytochemistry 65, 3097-3106.  http://www.sciencedirect.com/science/article/pii/S0031942204004224

Shin HJ, Kim YS, Kwak YS, Song YB, Kim YS and Park JD (2004) Enhancement of antitumor effects of paclitaxel (taxol) in combination with red ginseng acidic polysaccharide (RGAP). Planta medica. 70, 1033-1038.

Sreedhar AS, So″ti C and Csermely P (2004) Inhibition of Hsp90: a new strategy for inhibiting protein kinases. Biochimica et Biophysica Acta (BBA) - Proteins &amp; Proteomics 1697, 233-242.  http://www.sciencedirect.com/science/article/pii/S1570963903003790

Suye S-i, Nakamoto D, Hori T, Sugawara F and Mulchandani A (2004) A Tubulin-Based Quantitative Assay for Taxol (Paclitaxel) with Enzyme Channeling Sensing. Electroanalysis 16, 688-690.  http://dx.doi.org/10.1002/elan.200302873

Talebi M, Ghassempour A, Talebpour Z, Rassouli A and Dolatyari L (2004) Optimization of the extraction of paclitaxel from Taxus baccata L. by the use of microwave energy. Journal of Separation Science 27, 1130-1136.  http://dx.doi.org/10.1002/jssc.200401754

Voeks RA (2004) Disturbance Pharmacopoeias: Medicine and Myth from the Humid Tropics. Annals of the Association of American Geographers 94, 868-888.  http://dx.doi.org/10.1111/j.1467-8306.2004.00439.x

Vujanovic V (2004) Increased incidence of cryptocline needle disease on Pacific yew. Canadian plant disease survey = Inventaire des maladies des plantes au Canada., 84.  http://www.cps-scp.ca/download/cpds_v84.pdf

Walsh V and Le Roux M (2004) Contingency in innovation and the role of national systems: taxol and taxotčre in the USA and France. Research Policy 33, 1307-1327.  http://www.sciencedirect.com/science/article/pii/S0048733304001155

Wu J and Ge X (2004) Oxidative burst, jasmonic acid biosynthesis, and taxol production induced by low-energy ultrasound in Taxus chinensis cell suspension cultures. Biotechnology and Bioengineering 85, 714-721.  http://dx.doi.org/10.1002/bit.10911

Xu M, Hillwig ML, Prisic S, Coates RM and Peters RJ (2004) Functional identification of rice syn-copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products. The Plant Journal 39, 309-318.  http://dx.doi.org/10.1111/j.1365-313X.2004.02137.x

Yang H-L, Hseu Y-C, Hseu Y-T, Lu F-J, Lin E and Lai J-S (2004) Humic acid induces apoptosis in human premyelocytic leukemia HL-60 cells. Life Sciences 75, 1817-1831.  http://www.sciencedirect.com/science/article/pii/S0024320504004874

Zong Z-p, Matsui S, Katsuda S, Han J-f and Fujikawa-Yamamoto K (2004) Phorbol myristate induces apoptosis of taxol-resistant sarcoma cells in vitro. European Journal of Pharmacology 489, 3-11.  http://www.sciencedirect.com/science/article/pii/S0014299904001591

Asai Y, Hashimoto M and Ogawa T (2003) Treponemal glycoconjugate inhibits Toll-like receptor ligand-induced cell activation by blocking LPS-binding protein and CD14 functions. European Journal of Immunology 33, 3196-3204.  http://dx.doi.org/10.1002/eji.200324219

Bellmunt J, de Wit R, Albiol S, Tabernero J, Albanell J and Baselga J (2003) New drugs and new approaches in metastatic bladder cancer. Critical Reviews in Oncology/Hematology 47, 195-206.  http://www.sciencedirect.com/science/article/pii/S1040842803000829

Berg T (2003) Modulation von Protein-Protein-Wechselwirkungen mit niedermolekularen organischen Molekülen. Angewandte Chemie 115, 2566-2586.  http://dx.doi.org/10.1002/ange.200200558

Berg T (2003) Modulation of Protein–Protein Interactions with Small Organic Molecules. Angewandte Chemie International Edition 42, 2462-2481.  http://dx.doi.org/10.1002/anie.200200558

Beusker Patrick H, Veldhuis H, Brinkhorst J, Hetterscheid Dennis GH, Feichter N, Bugaut A and Scheeren Hans W (2003) Semisynthesis of 7-Deoxypaclitaxel Derivatives Devoid of an Oxetane D-Ring, Starting from Taxine B. European Journal of Organic Chemistry 2003, 689-705.  http://dx.doi.org/10.1002/ejoc.200390109

Blagg BSJ, Hadden MK and Abraham DJ (2003) Hsp90 Inhibitors. In ‘Burger’s Medicinal Chemistry and Drug Discovery’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471266949.bmc212

Bonfill M, Palazón J, Cusidó Rosa M, Joly S, Morales C and Teresa Pińol M (2003) Influence of elicitors on taxane production and 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in Taxus media cells. Plant Physiology and Biochemistry 41, 91-96.  http://www.sciencedirect.com/science/article/pii/S098194280200013X

Camille G W (2003) 33 - Designing Prodrugs and Bioprecursors. In ‘The Practice of Medicinal Chemistry (Second Edition)’ (Ed.^(Eds Camille GW) pp. 561-585. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780127444819500374

Carey AB (2003) Biocomplexity and restoration of biodiversity in temperate coniferous forest: inducing spatial heterogeneity with variable-density thinning. Forestry 76, 127-136.  http://forestry.oxfordjournals.org/cgi/content/abstract/76/2/127

Carter GT, Bernan VS, Koehn FE and Abraham DJ (2003) New Strategies for Natural Products Lead Generation. In ‘Burger’s Medicinal Chemistry and Drug Discovery’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471266949.bmc116

Chan-Bacab MJ, Balanza E, Deharo E, Muńoz V, Garcı́a RD and Peńa-Rodrı́guez LM (2003) Variation of leishmanicidal activity in four populations of Urechites andrieuxii. Journal of Ethnopharmacology 86, 243-247.  http://www.sciencedirect.com/science/article/pii/S0378874103000114

Cooper NJ, Abrams KR, Sutton AJ, Turner D and Lambert PC (2003) A Bayesian approach to Markov modelling in cost-effectiveness analyses: application to taxane use in advanced breast cancer. Journal of the Royal Statistical Society: Series A (Statistics in Society) 166, 389-405.  http://dx.doi.org/10.1111/1467-985X.00283

Cragg GM and Newman DJ (2003) Plants as a source of anti-cancer and anti-HIV agents. Annals of Applied Biology 143, 127-133.  http://dx.doi.org/10.1111/j.1744-7348.2003.tb00278.x

Craik DJ, Smith PA, Clark RJ and Abraham DJ (2003) NMR-Based Screening and Drug Discovery. In ‘Burger’s Medicinal Chemistry and Drug Discovery’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471266949.bmc011.pub2

Dettki H and Esseen P-A (2003) Modelling long-term effects of forest management on epiphytic lichens in northern Sweden. Forest Ecology and Management 175, 223-238.  http://www.sciencedirect.com/science/article/pii/S0378112702001317

Edelstein ZR and Ford ED (2003) Branch and foliage morphological plasticity in old-growth Thuja plicata. Tree Physiol 23, 649-662.  http://treephys.oxfordjournals.org/cgi/content/abstract/23/10/649

Feng S-S and Chien S (2003) Chemotherapeutic engineering: Application and further development of chemical engineering principles for chemotherapy of cancer and other diseases. Chemical Engineering Science 58, 4087-4114.  http://www.sciencedirect.com/science/article/pii/S0009250903002343

Ferlini C, Ojima I, Distefano M, Gallo D, Riva A, Morazzoni P, Bombardelli E, Mancuso S and Scambia G (2003) Second generation taxanes: from the natural framework to the challenge of drug resistance. Curr Med Chem Anticancer Agents 3, 133-8.

Fitzpatrick FA and Wheeler R (2003) The immunopharmacology of paclitaxel (Taxol®), docetaxel (Taxotere®), and related agents. International Immunopharmacology 3, 1699-1714.  http://www.sciencedirect.com/science/article/pii/S1567576903002078

François C (2003) 1 - A Brief History of Drugs: From Plant Extracts to DNA Technology. In ‘The Practice of Medicinal Chemistry (Second Edition)’ (Ed.^(Eds Camille GW) pp. 3-28. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780127444819500052

Ghetti E, Piraccini BM and Tosti A (2003) Onycholysis and subungual haemorrhages secondary to systemic chemotherapy (paclitaxel). Journal of the European Academy of Dermatology and Venereology 17, 459-460.  http://dx.doi.org/10.1046/j.1468-3083.2003.00774.x

Giner J-L and Faraldos JA (2003) Facile Orthoester Formation in a Model Compound of the Taxol Oxetane: Are Biologically Active Epoxy Esters, Orthoesters, and Oxetanyl Esters Latent Electrophiles? Helvetica Chimica Acta 86, 3613-3622.  http://dx.doi.org/10.1002/hlca.200390306

Goble S and Bear HD (2003) Emerging role of taxanes in adjuvant and neoadjuvant therapy for breast cancer: The potential and the questions. Surgical Clinics of North America 83, 943-971.  http://www.sciencedirect.com/science/article/pii/S0039610903000719

Hudgins JW, Christiansen E and Franceschi VR (2003) Methyl jasmonate induces changes mimicking anatomical defenses in diverse members of the Pinaceae. Tree Physiol 23, 361-371.  http://treephys.oxfordjournals.org/cgi/content/abstract/23/6/361

Hudgins JW, Krekling T and Franceschi VR (2003) Distribution of calcium oxalate crystals in the secondary phloem of conifers: a constitutive defense mechanism? New Phytologist 159, 677-690.  http://dx.doi.org/10.1046/j.1469-8137.2003.00839.x

Ikeda K, Sakai Y and Nagase H (2003) Inhibitory effect of magnolol on tumour metastasis in mice. Phytotherapy Research 17, 933-937.  http://dx.doi.org/10.1002/ptr.1264

Jeewon R, Liew ECY, Simpson JA, John Hodgkiss I and Hyde KD (2003) Phylogenetic significance of morphological characters in the taxonomy of Pestalotiopsis species. Molecular Phylogenetics and Evolution 27, 372-383.  http://www.sciencedirect.com/science/article/pii/S1055790303000101

Ketchum REB, Rithner CD, Qiu D, Kim YS, Williams RM and Croteau RB (2003) Taxus metabolomics: methyl jasmonate preferentially induces production of taxoids oxygenated at C-13 in Taxus x media cell cultures. Phytochemistry 62, 901-909.  http://www.sciencedirect.com/science/article/pii/S0031942202007112

Kinghorn AD and Chávez D (2003) SECONDARY PRODUCTS | Pharmaceuticals, Plant Drugs. In ‘Encyclopedia of Applied Plant Sciences’ (Ed.^(Eds Editor-in-Chief:   Brian T) pp. 1145-1152. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B0122270509001265

Komaraiah P, Ramakrishna SV, Reddanna P and Kavi Kishor PB (2003) Enhanced production of plumbagin in immobilized cells of Plumbago rosea by elicitation and in situ adsorption. Journal of Biotechnology 101, 181-187.  http://www.sciencedirect.com/science/article/pii/S0168165602003383

Küpeli E, Erdemoğlu N, Yeşilada E and Şener B (2003) Anti-inflammatory and antinociceptive activity of taxoids and lignans from the heartwood of Taxus baccata L. Journal of Ethnopharmacology 89, 265-270.  http://www.sciencedirect.com/science/article/pii/S0378874103003118

Kuruma H, Fujita T, Shitara T, Egawa S, Yokoyama E and Baba S (2003) Weekly paclitaxel plus estramustine combination therapy in hormone-refractory prostate cancer: A pilot study. International Journal of Urology 10, 470-475.  http://dx.doi.org/10.1046/j.1442-2042.2003.00671.x

Lee MS (2003) LC/MS Applications. In ‘LC/MS Applications in Drug Development’ (Ed.^(Eds  pp. 65-182. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471218812.ch6

Lee MS (2003) Index. In ‘LC/MS Applications in Drug Development’ (Ed.^(Eds  pp. 235-243. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471218812.index

Mohamed F and Sugarbaker PH (2003) Intraperitoneal taxanes. Surgical Oncology Clinics of North America 12, 825-833.  http://www.sciencedirect.com/science/article/pii/S1055320703000383

Morais S, O’Malley S, Chen W and Mulchandani A (2003) A tubulin-based fluorescent polarization assay for paclitaxel. Analytical Biochemistry 321, 44-49.  http://www.sciencedirect.com/science/article/pii/S0003269703004366

Mouw JEB and Alaback PB (2003) Putting floodplain hyperdiversity in a regional context: an assessment of terrestrial–floodplain connectivity in a montane environment. Journal of Biogeography 30, 87-103.  http://dx.doi.org/10.1046/j.1365-2699.2003.00775.x

New DC, Miller-Martini DM and Wong YH (2003) Reporter gene assays and their applications to bioassays of natural products. Phytotherapy Research 17, 439-448.  http://dx.doi.org/10.1002/ptr.1312

Nguyen NT, Banskota AH, Tezuka Y, Nobukawa T and Kadota S (2003) Diterpenes and sesquiterpenes from the bark of Taxus yunnanensis. Phytochemistry 64, 1141-1147.  http://www.sciencedirect.com/science/article/pii/S003194220300503X

Oberlies NH, Greer JA and Wani MC (2003) Taxol discovery commemorated in Washington state; plaque honors researchers Wall and Wani, and the first Pacific yew collection. HerbalGram. 57, 57.

Palazón J, Cusidó RM, Bonfill M, Morales C and Pińol MT (2003) Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. Journal of Biotechnology 101, 157-163.  http://www.sciencedirect.com/science/article/pii/S0168165602003188

Paridaens R, Van Aelst F, et al. (2003) A randomized phase II study of alternating and sequential regimens of docetaxel and doxorubicin as first-line chemotherapy for metastatic breast cancer. Ann. Onc. 14, 433-440.  http://annonc.oxfordjournals.org/cgi/content/abstract/14/3/433

Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons G-J and Leibovich SJ (2003) An Angiogenic Switch in Macrophages Involving Synergy between Toll-Like Receptors 2, 4, 7, and 9 and Adenosine A2A Receptors. The American Journal of Pathology 163, 711-721.  http://www.sciencedirect.com/science/article/pii/S000294401063698X

Rajagopal S, Kumar RA, Deevi DS, Satyanarayana C and Rajagopalan R (2003) Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata. Journal of Experimental Therapeutics and Oncology 3, 147-158.  http://dx.doi.org/10.1046/j.1359-4117.2003.01090.x

Romero-Puertas M and Delledonne M (2003) Nitric Oxide Signaling in Plant-Pathogen Interactions. IUBMB Life 55, 579-583.  http://dx.doi.org/10.1080/15216540310001639274

Senn J and Suter W (2003) Ungulate browsing on silver fir (Abies alba) in the Swiss Alps: beliefs in search of supporting data. Forest Ecology and Management 181, 151-164.  http://www.sciencedirect.com/science/article/pii/S0378112703001294

Silber S (2003) Paclitaxel-Eluting Stents: Are They All Equal? Journal of Interventional Cardiology 16, 485-490.  http://dx.doi.org/10.1046/j.1540-8183.2003.01065.x

Takeda K and Akira S (2003) Toll receptors and pathogen resistance. Cellular Microbiology 5, 143-153.  http://dx.doi.org/10.1046/j.1462-5822.2003.00264.x

Thomas PA and Polwart A (2003) Taxus baccata L. Journal of Ecology 91, 489-524.  http://dx.doi.org/10.1046/j.1365-2745.2003.00783.x

Veng L, Savage MJ, Barrow JC, Zerbinatti CV and Abraham DJ (2003) Non-amyloid Approaches To Alzheimer’s Disease. In ‘Burger’s Medicinal Chemistry and Drug Discovery’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471266949.bmc253

Watanabe H, Yamamoto N, et al. (2003) Study of Paclitaxel and Dose Escalation of Cisplatin in Patients with Advanced Non-small Cell Lung Cancer. Jpn. J. Clin. Oncol. 33, 626-630.  http://jjco.oxfordjournals.org/cgi/content/abstract/33/12/626

Yang C-C, Chen G-W, Lu H-F, Wang D-Y, Chen Y-S and Chung J-G (2003) Paclitaxel (Taxol) Inhibits the Arylamine N-Acetyltransferase Activity and Gene Expression (mRNA NAT1) and 2-Aminofluorene-DNA Adduct Formation in Human Bladder Carcinoma Cells (T24 and TSGH 8301). Pharmacology & Toxicology 92, 287-294.  http://dx.doi.org/10.1034/j.1600-0773.2003.920606.x

Asok B (2002) Increased levels of tyrosinated α-, βIII-, and βIV-tubulin isotypes in paclitaxel-resistant MCF-7 breast cancer cells. Biochemical and Biophysical Research Communications 293, 598-601.  http://www.sciencedirect.com/science/article/pii/S0006291X02002693

Braga SF and Galvăo DS (2002) A semiempirical study on the electronic structure of 10-deacetylbaccatin-III. Journal of Molecular Graphics and Modelling 21, 57-70.  http://www.sciencedirect.com/science/article/pii/S1093326302001213

Brincat MC, Gibson DM and Shuler ML (2002) Alterations in Taxol Production in Plant Cell Culture via Manipulation of the Phenylalanine Ammonia Lyase Pathway. Biotechnology Progress 18, 1149-1156.  http://dx.doi.org/10.1021/bp0256115

Bruce C B (2002) Chapter 1 - A brief history of cancer chemotherapy. In ‘Anticancer Drug Development’ (Ed.^(Eds Bruce CB and David JK) pp. 1-11. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780120726516500024

Busing RT and Fujimori T (2002) Dynamics of composition and structure in an old Sequoia sempervirens forest. Journal of Vegetation Science 13, 785-792.  http://dx.doi.org/10.1111/j.1654-1103.2002.tb02108.x

Chen W-Y, Yang Y-M and Chuang N-N (2002) Selective enhanced phosphorylation of shrimp β-tubulin by PKC-δ with PEPtaxol, a synthetic peptide encoding the taxol binding region. Journal of Experimental Zoology 292, 376-383.  http://dx.doi.org/10.1002/jez.10063

Fornalč S, Esposti DD, Navia-Osorio A, Cusidň RM, Palazňn J, Teresa Pińol M and Bagni N (2002) Taxol transport in Taxus baccata cell suspension cultures. Plant Physiology and Biochemistry 40, 81-88.  http://www.sciencedirect.com/science/article/pii/S0981942801013328

Hsia TC, Chung JG, Lu HF, Ho HC, Yang CC, Lu KH and Hung CF (2002) The effect of paclitaxel on 2-aminofluorene–DNA adducts formation and arylamine N-acetyltransferase activity and gene expression in human lung tumor cells (A549). Food and Chemical Toxicology 40, 697-703.  http://www.sciencedirect.com/science/article/pii/S0278691501001284

Huang S-Q and Guo Y-H (2002) Variation of pollination and resource limitation in a low seed-set tree, Liriodendron chinense (Magnoliaceae). Botanical Journal of the Linnean Society 140, 31-38.  http://dx.doi.org/10.1046/j.1095-8339.2002.00080.x

Ishii H, Ford ED, Boscolo ME, Manriquez AC, Wilson ME and Hinckley TM (2002) Variation in specific needle area of old-growth Douglas-fir in relation to needle age, within-crown position and epicormic shoot production. Tree Physiol 22, 31-40.  http://treephys.oxfordjournals.org/cgi/content/abstract/22/1/31

Janisch JE and Harmon ME (2002) Successional changes in live and dead wood carbon stores: implications for net ecosystem productivity. Tree Physiol 22, 77-89.  http://treephys.oxfordjournals.org/cgi/content/abstract/22/2-3/77

Jian-Jiang Z (2002) Plant cell culture for production of paclitaxel and other taxanes. Journal of Bioscience and Bioengineering 94, 591-599.  http://www.sciencedirect.com/science/article/pii/S1389172302802006

Jimenez-Barbero J, Amat-Guerri F and Snyder JP (2002) The solid state, solution and tubulin-bound conformations of agents that promote microtubule stabilization. Curr Med Chem Anticancer Agents 2, 91-122.

Kierszenbaum AL, Gil M, Rivkin E and Tres LL (2002) Ran, a GTP-binding protein involved in nucleocytoplasmic transport and microtubule nucleation, relocates from the manchette to the centrosome region during rat spermiogenesis. Molecular Reproduction and Development 63, 131-140.  http://dx.doi.org/10.1002/mrd.10164

Kim JH, Kang IS, Choi HK, Hong SS and Lee HS (2002) A novel prepurification for paclitaxel from plant cell cultures. Process Biochemistry 37, 679-682.  http://www.sciencedirect.com/science/article/pii/S0032959201002473

Kobayashi TK, Moritani S, Bamba M, Fujimoto Y, Urabe M and Kaneko C (2002) Effects of Taxol on ascites cytology from a patient with fallopian tube carcinoma: Report of a case with ultrastructural studies. Diagnostic Cytopathology 27, 132-134.  http://dx.doi.org/10.1002/dc.10144

Li W and Ma H (2002) Gametophyte development. Current Biology 12, R718-R721.  http://www.sciencedirect.com/science/article/pii/S0960982202012459

Lorenz SA, Bigwarfe PM, Balasubramanian SV, Fetterly GJ, Straubinger RM and Wood TD (2002) Noncovalent dimerization of paclitaxel in solution: Evidence from electrospray ionization mass spectrometry. Journal of Pharmaceutical Sciences 91, 2057-2066.  http://dx.doi.org/10.1002/jps.10194

Lu KH, Lin KL, Yang CC, Hsia TC, Hsiao YM, Chou MC, Ho HC and Chung JG (2002) The effect of paclitaxel on gene expression and activity of arylamine N-acetyltransferase and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells. Food and Chemical Toxicology 40, 705-713.  http://www.sciencedirect.com/science/article/pii/S0278691501001296

Luch A (2002) Cell Cycle Control and Cell Division: Implications for Chemically Induced Carcinogenesis. ChemBioChem 3, 506-516.  http://dx.doi.org/10.1002/1439-7633(20020603)3:6<506::AID-CBIC506>3.0.CO;2-V

M. Cusidó R, Palazón J, Bonfill M, Navia-Osorio A, Morales C and Pińol MT (2002) Improved Paclitaxel and Baccatin III Production in Suspension Cultures of Taxusmedia. Biotechnology Progress 18, 418-423.  http://dx.doi.org/10.1021/bp0101583

Madhusudanan KP, Chattopadhyay SK, Tripathi V, Sashidhara KV and Kumar S (2002) MS/MS profiling of taxoids from the needles of Taxus wallichiana. Phytochemical Analysis 13, 18-30.  http://dx.doi.org/10.1002/pca.610

Madhusudanan KP, Chattopadhyay SK, Tripathi VK, Sashidhara KV, Kukreja AK and Jain SP (2002) LC-ESI-MS analysis of taxoids from the bark of Taxus wallichiana. Biomedical Chromatography 16, 343-355.  http://dx.doi.org/10.1002/bmc.163

Masuda T, Oyama Y, et al. (2002) Flow cytometric estimation on cytotoxic activity of leaf extracts from seashore plants in subtropical Japan: isolation, quantification and cytotoxic action of (-)-deoxypodophyllotoxin. Phytotherapy Research 16, 353-358.  http://dx.doi.org/10.1002/ptr.902

Miglietta A, Bocca C and Gabriel L (2002) Comparative studies on biological activity of certain microtubule-interacting taxanes. Chemico-Biological Interactions 139, 283-299.  http://www.sciencedirect.com/science/article/pii/S0009279702000078

Mu L and Feng SS (2002) Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol®). Journal of Controlled Release 80, 129-144.  http://www.sciencedirect.com/science/article/pii/S0168365902000251

Nadeem M, Rikhari HC, Kumar A, Palni LMS and Nandi SK (2002) Taxol content in the bark of Himalayan Yew in relation to tree age and sex. Phytochemistry 60, 627-631.  http://www.sciencedirect.com/science/article/pii/S0031942202001152

Navia-Osorio A, Garden H, Cusidó RM, Palazón J, Alfermann AW and Pińol MT (2002) Taxol® and baccatin III production in suspension cultures of Taxus baccata and Taxus wallichiana in an airlift bioreactor. Journal of Plant Physiology 159, 97-102.  http://www.sciencedirect.com/science/article/pii/S0176161704702102

Özkan L, Egeli Ü, et al. (2002) Investigation of genotoxic effect of taxol plus radiation on mice bone marrow cells. Teratogenesis, Carcinogenesis, and Mutagenesis 22, 1-11.  http://dx.doi.org/10.1002/tcm.1034

Parc G, Canaguier A, Landré P, Hocquemiller R, Chriqui D and Meyer M (2002) Production of taxoids with biological activity by plants and callus culture from selected Taxus genotypes. Phytochemistry 59, 725-730.  http://www.sciencedirect.com/science/article/pii/S0031942202000432

Parekh HK, Deng HB, Choudhary K, Houser SR and Simpkins H (2002) Overexpression of sorcin, a calcium-binding protein, induces a low level of paclitaxel resistance in human ovarian and breast cancer cells. Biochemical Pharmacology 63, 1149-1158.  http://www.sciencedirect.com/science/article/pii/S000629520200850X

Peterson JR and Mitchison TJ (2002) Small Molecules, Big Impact: A History of Chemical Inhibitors and the Cytoskeleton. Chemistry &amp; Biology 9, 1275-1285.  http://www.sciencedirect.com/science/article/pii/S1074552102002843

Podstolski A, Havkin-Frenkel D, Malinowski J, Blount JW, Kourteva G and Dixon RA (2002) Unusual 4-hydroxybenzaldehyde synthase activity from tissue cultures of the vanilla orchid Vanilla planifolia. Phytochemistry 61, 611-620.  http://www.sciencedirect.com/science/article/pii/S0031942202002856

Price KS and Castells MC (2002) Taxol reactions. Allergy Asthma Proc 23, 205-8.

Ron W (2002) Drug-eluting stents: From bench to bed. Cardiovascular Radiation Medicine 3, 226-241.  http://www.sciencedirect.com/science/article/pii/S152218650300115X

Sakihama Y, Nakamura S and Yamasaki H (2002) Nitric Oxide Production Mediated by Nitrate Reductase in the Green Alga Chlamydomonas reinhardtii: an Alternative NO Production Pathway in Photosynthetic Organisms. Plant Cell Physiol. 43, 290-297.  http://pcp.oxfordjournals.org/cgi/content/abstract/43/3/290

Seo JH, Whang YM, Kim BS, Choi CW, Shin SW, Kim YH, Kim JS and Goo BH (2002) A Phase II study of paclitaxel by 24-hour infusion and ifosfamide in anthracycline-resistant metastatic breast carcinoma. Cancer 94, 1925-1930.  http://dx.doi.org/10.1002/cncr.10431

Singla AK, Garg A and Aggarwal D (2002) Paclitaxel and its formulations. International Journal of Pharmaceutics 235, 179-192.  http://www.sciencedirect.com/science/article/pii/S0378517301009863

Stohr C and Ullrich WR (2002) Generation and possible roles of NO in plant roots and their apoplastic space. J. Exp. Bot. 53, 2293-2303.  http://jxb.oxfordjournals.org/cgi/content/abstract/53/379/2293

Strohl WR (2002) Secondary Metabolites, Antibiotics. In ‘Encyclopedia of Bioprocess Technology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471250589.ebt196

Tikhomiroff C, Allais S, Klvana M, Hisiger S and Jolicoeur M (2002) Continuous Selective Extraction of Secondary Metabolites from Catharanthus roseus Hairy Roots with Silicon Oil in a Two-Liquid-Phase Bioreactor. Biotechnology Progress 18, 1003-1009.  http://dx.doi.org/10.1021/bp0255558

White JG and de Alarcon PA (2002) Platelet spherocytosis: A new bleeding disorder. American Journal of Hematology 70, 158-166.  http://dx.doi.org/10.1002/ajh.10098

Yuan Y-J, Wei Z-J, Miao Z-Q and Wu J-C (2002) Acting paths of elicitors on Taxol biosynthesis pathway and their synergistic effect. Biochemical Engineering Journal 10, 77-83.  http://www.sciencedirect.com/science/article/pii/S1369703X01001590

Ziske CG, Schottker B, Gorschluter M, Mey U, Kleinschmidt R, Schlegel U, Sauerbruch T and Schmidt-Wolf IGH (2002) Acute transient encephalopathy after paclitaxel infusion: report of three cases. Ann. Onc. 13, 629-631.  http://annonc.oxfordjournals.org/cgi/content/abstract/13/4/629

Anderson ED and Owens JN (2001) Embryo development, megagametophyte storage product accumulation, and seed efficiency in Taxus brevifolia. Canadian journal of forest research. 31, 1046-1056.

Ansell SM, Pitot HC, Burch PA, Kvols LK, Mahoney MR and Rubin J (2001) A Phase II study of high-dose paclitaxel in patients with advanced neuroendocrine tumors. Cancer 91, 1543-1548.  http://dx.doi.org/10.1002/1097-0142(20010415)91:8<1543::AID-CNCR1163>3.0.CO;2-N

Beusker Patrick H, Veldhuis H, van den Bossche Bianca AC and Scheeren Hans W (2001) Semisynthesis of Flexible 5,7-Dideoxypaclitaxel Derivatives from Taxine B. European Journal of Organic Chemistry 2001, 1761-1768.  http://dx.doi.org/10.1002/1099-0690(200105)2001:9<1761::AID-EJOC1761>3.0.CO;2-O

Beutler JA (2001) Natural Products as a Foundation for Drug Discovery. In ‘Current Protocols in Pharmacology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471141755.ph0911s46

Byrd-Leifer CA, Block EF, Takeda K, Akira S and Ding A (2001) The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol. European Journal of Immunology 31, 2448-2457.  http://dx.doi.org/10.1002/1521-4141(200108)31:8<2448::AID-IMMU2448>3.0.CO;2-N

Campbell RB, Balasubramanian SV and Straubinger RM (2001) Influence of cationic lipids on the stability and membrane properties of paclitaxel-containing liposomes. Journal of Pharmaceutical Sciences 90, 1091-1105.  http://dx.doi.org/10.1002/jps.1063

Chen DB, Yang TZ, Lu WL and Zhang Q (2001) In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel. Chem Pharm Bull (Tokyo) 49, 1444-7.

Corbet SA, Bee J, et al. (2001) Native or Exotic? Double or Single? Evaluating Plants for Pollinator-friendly Gardens. Ann. Bot. 87, 219-232.  http://aob.oxfordjournals.org/cgi/content/abstract/87/2/219

Cragg GM and Newman DJ (2001) Medicinals for the Millennia. Annals of the New York Academy of Sciences 953a, 3-25.  http://dx.doi.org/10.1111/j.1749-6632.2001.tb11356.x

Cristofanilli M and Hortobagyi GN (2001) New Horizons in Treating Metastatic Disease. Clinical Breast Cancer 1, 276-287.  http://www.sciencedirect.com/science/article/pii/S1526820911701434

da Rocha AB, Lopes RM and Schwartsmann G (2001) Natural products in anticancer therapy. Current Opinion in Pharmacology 1, 364-369.  http://www.sciencedirect.com/science/article/pii/S1471489201000637

Day-Rubenstein K and Frisvold GB (2001) Genetic prospecting and biodiversity development agreements. Land use policy. 18, 3.  http://hdl.handle.net/10113/38719 http://dx.doi.org/10.1016/S0264-8377(01)00016-3

Devarenne TP (2001) Terpenoids: Higher. In ‘eLS’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470015902.a0001916.pub2

Dewick PM (2001) The Mevalonate and Deoxyxylulose Phosphate Pathways: Terpenoids and Steroids. In ‘Medicinal Natural Products’ (Ed.^(Eds  pp. 167-289. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/0470846275.ch5

Dewick PM (2001) Front Matter and Index. In ‘Medicinal Natural Products’ (Ed.^(Eds  pp. i-xii. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/0470846275.fmatter_indsub

Dimitriadis I, Katsaros C and Galatis B (2001) The effect of taxol on centrosome function and microtubule organization in apical cells of Sphacelaria rigidula (Phaeophyceae). Phycological Research 49, 23-34.  http://dx.doi.org/10.1046/j.1440-1835.2001.00222.x

Dong H-D and Zhong J-J (2001) Significant improvement of taxane production in suspension cultures of Taxus chinensis by combining elicitation with sucrose feed. Biochemical Engineering Journal 8, 145-150.  http://www.sciencedirect.com/science/article/pii/S1369703X01000961

Febvre-Chevalier C and Febvre J (2001) Heliozoa. In ‘eLS’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1038/npg.els.0002103

Feng S-s and Huang G (2001) Effects of emulsifiers on the controlled release of paclitaxel (Taxol®) from nanospheres of biodegradable polymers. Journal of Controlled Release 71, 53-69.  http://www.sciencedirect.com/science/article/pii/S0168365900003643

Fester K (2001) Plant Alkaloids. In ‘eLS’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470015902.a0001914.pub2

Fetterly GJ, Tamburlin JM and Straubinger RM (2001) Paclitaxel pharmacodynamics: application of a mechanism-based neutropenia model. Biopharmaceutics & Drug Disposition 22, 251-261.  http://dx.doi.org/10.1002/bdd.283

Fujikawa-Yamamoto K, Wang S, Yamagishi H, Ohdoi C, Murano H and Ikeda T (2001) Establishment of a tetraploid Meth-A cell line through polyploidization by demecolcine but not by staurosporine, K-252A and paclitaxel. Cell Proliferation 34, 211-222.  http://dx.doi.org/10.1046/j.1365-2184.2001.00204.x

Garces H, Durzan D and Pedroso MC (2001) Mechanical Stress Elicits Nitric Oxide Formation and DNA Fragmentation in Arabidopsis thaliana. Ann. Bot. 87, 567-574.  http://aob.oxfordjournals.org/cgi/content/abstract/87/5/567

Gardiner ES and Krauss KW (2001) Photosynthetic light response of flooded cherrybark oak (Quercus pagoda) seedlings grown in two light regimes. Tree Physiol 21, 1103-1111.  http://treephys.oxfordjournals.org/cgi/content/abstract/21/15/1103

Gelderblom H, Verweij J, Nooter K and Sparreboom A (2001) Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. European Journal of Cancer 37, 1590-1598.  http://www.sciencedirect.com/science/article/pii/S095980490100171X

Gruber D, Faire K and Bulinski JC (2001) Abundant expression of the microtubule-associated protein, ensconsin (E-MAP-115), alters the cellular response to Taxol. Cell Motility and the Cytoskeleton 49, 115-129.  http://dx.doi.org/10.1002/cm.1026

He L, Orr GA and Horwitz SB (2001) Novel molecules that interact with microtubules and have functional activity similar to Taxol™. Drug Discovery Today 6, 1153-1164.  http://www.sciencedirect.com/science/article/pii/S1359644601020384

He L, Orr GA and Horwitz SB (2001) Novel molecules that interact with microtubules and have functional activity similar to Taxol. Drug Discov Today 6, 1153-1164.

Ho Y-S, Duh J-S, et al. (2001) Griseofulvin potentiates antitumorigenesis effects of nocodazole through induction of apoptosis and G2/M cell cycle arrest in human colorectal cancer cells. International Journal of Cancer 91, 393-401.  http://dx.doi.org/10.1002/1097-0215(200002)9999:9999<::AID-IJC1070>3.0.CO;2-#

Jones GB (2001) History of Anticancer Drugs. In ‘eLS’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1038/npg.els.0003630

Kim SC, Kim DW, Shim YH, Bang JS, Oh HS, Kim SW and Seo MH (2001) In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy. Journal of Controlled Release 72, 191-202.  http://www.sciencedirect.com/science/article/pii/S0168365901002759

Kim S-I, Choi H-K, Kim J-H, Lee H-S and Hong S-S (2001) Effect of osmotic pressure on paclitaxel production in suspension cell cultures of Taxus chinensis. Enzyme and Microbial Technology 28, 202-209.  http://www.sciencedirect.com/science/article/pii/S0141022900002921

Kurata T, Tamura T, et al. (2001) Phase I and Pharmacological Study of Paclitaxel Given Over 3 h with Cisplatin for Advanced Non-small Cell Lung Cancer. Jpn. J. Clin. Oncol. 31, 93-99.  http://jjco.oxfordjournals.org/cgi/content/abstract/31/3/93

Kurose A, Yoshida W, Yoshida M and Sawai T (2001) Effects of paclitaxel on cultured synovial cells from patients with rheumatoid arthritis. Cytometry 44, 349-354.  http://dx.doi.org/10.1002/1097-0320(20010801)44:4<349::AID-CYTO1126>3.0.CO;2-O

Lev-Yadun S (2001) Bark. In ‘eLS’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470015902.a0002078.pub2

Li JY, Harper JK, Grant DM, Tombe BO, Bashyal B, Hess WM and Strobel GA (2001) Ambuic acid, a highly functionalized cyclohexenone with antifungal activity from Pestalotiopsis spp. and Monochaetia sp. Phytochemistry 56, 463-468.  http://www.sciencedirect.com/science/article/pii/S0031942200004088

Li S, Zhang H, Yao P, Sun H and Fong HHS (2001) Taxane diterpenoids from the bark of Taxus yunnanensis. Phytochemistry 58, 369-374.  http://www.sciencedirect.com/science/article/pii/S0031942201002187

Loprevite M, Favoni RE, de Cupis A, Pirani P, Pietra G, Bruno S, Grossi F, Scolaro T and Ardizzoni A (2001) Interaction between novel anticancer agents and radiation in non-small cell lung cancer cell lines. Lung Cancer 33, 27-39.  http://www.sciencedirect.com/science/article/pii/S0169500200002476

Mark M, Walter R, Meredith DO and Reinhart WH (2001) Commercial taxane formulations induce stomatocytosis and increase blood viscosity. British Journal of Pharmacology 134, 1207-1214.  http://dx.doi.org/10.1038/sj.bjp.0704387

Mayerhofer K, Bodner K, et al. (2001) Interleukin-8 serum level shift in patients with ovarian carcinoma undergoing paclitaxel-containing chemotherapy. Cancer 91, 388-393.  http://dx.doi.org/10.1002/1097-0142(20010115)91:2<388::AID-CNCR1013>3.0.CO;2-B

Miglietta A, Bocca C, Gabriel L, Rampa A, Bisi A and Valenti P (2001) Antimicrotubular and cytotoxic activity of geiparvarin analogues, alone and in combination with paclitaxel. Cell Biochemistry and Function 19, 181-189.  http://dx.doi.org/10.1002/cbf.919

Miller ML and Ojima I (2001) Chemistry and chemical biology of taxane anticancer agents. The Chemical Record 1, 195-211.  http://dx.doi.org/10.1002/tcr.1008

Niell HB, Perry MC, Clamon G, Crawford J, Miller AA, Herndon Ii J and Green MR (2001) Carboplatin/Etoposide/Paclitaxel in the Treatment of Patients with Extensive Small-Cell Lung Cancer. Clinical Lung Cancer 2, 204-209.  http://www.sciencedirect.com/science/article/pii/S1525730411707239

Oberhoff M, Herdeg C, Al Ghobainy R, Cetin S, Küttner A, Horch B, Baumbach A and Karsch KR (2001) Local delivery of paclitaxel using the double-balloon perfusion catheter before stenting in the porcine coronary artery. Catheterization and Cardiovascular Interventions 53, 562-568.  http://dx.doi.org/10.1002/ccd.1223

Paál K, Müller J and Hegedűs L (2001) High affinity binding of paclitaxel to human serum albumin. European Journal of Biochemistry 268, 2187-2191.  http://dx.doi.org/10.1046/j.1432-1327.2001.02107.x

Pradier O, Rave-Fränk M, Lehmann J, Lücke E, Boghun O, Hess C-F and Schmidberger H (2001) Effects of docetaxel in combination with radiation on human head and neck cancer cells (ZMK-1) and cervical squamous cell carcinoma cells (CaSki ). International Journal of Cancer 91, 840-845.  http://dx.doi.org/10.1002/1097-0215(200002)9999:9999<::AID-IJC1142>3.0.CO;2-U

Prasain JK, Stefanowicz P, Kiyota T, Habeichi F and Konishi Y (2001) Taxines from the needles of Taxus wallichiana. Phytochemistry 58, 1167-1170.  http://www.sciencedirect.com/science/article/pii/S0031942201003053

Premoli AC, Souto CP, Allnutt TR and Newton AC (2001) Effects of population disjunction on isozyme variation in the widespread Pilgerodendron uviferum. Heredity 87, 337-343.  http://dx.doi.org/10.1046/j.1365-2540.2001.00906.x

Ram VJ and Kumari S (2001) Natural products of plant origin as anticancer agents. Drug News Perspect 14, 465-82.

Rohl J, Kushner D and Markman M (2001) Chronic Administration of Single-Agent Paclitaxel in Gynecologic Malignancies. Gynecologic Oncology 81, 201-205.  http://www.sciencedirect.com/science/article/pii/S0090825801961426

Santos-Silva MC, Sampaio de Freitas M and Assreuy J (2001) Killing of lymphoblastic leukemia cells by nitric oxide and taxol: involvement of NF-κB activity. Cancer Letters 173, 53-61.  http://www.sciencedirect.com/science/article/pii/S0304383501006644

Seidman R, Gitelman I, Sagi O, Horwitz SB and Wolfson M (2001) The Role of ERK ˝ and p38 MAP-Kinase Pathways in Taxol-Induced Apoptosis in Human Ovarian Carcinoma Cells. Experimental Cell Research 268, 84-92.  http://www.sciencedirect.com/science/article/pii/S0014482701952620

Sheikh SH and Mulchandani A (2001) Continuous-flow fluoro-immunosensor for paclitaxel measurement. Biosensors and Bioelectronics 16, 647-652.  http://www.sciencedirect.com/science/article/pii/S0956566301001932

Strobel GA (2001) Taxol. In ‘eLS’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1038/npg.els.0001917

Tai C-J, Wang W-S, Liu J-H, Yen C-C, Fan FS, Chiou T-J and Chen P-M (2001) Salvage Therapy with Single-agent Paclitaxel by Three-hour Infusion in Metastatic Breast Cancer: an Experience in Taipei Veterans General Hospital. Jpn. J. Clin. Oncol. 31, 477-481.  http://jjco.oxfordjournals.org/cgi/content/abstract/31/10/477

Takeda K and Akira S (2001) Toll-Like Receptors. In ‘Current Protocols in Immunology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471142735.im1412s77

Trapp SC and Croteau RB (2001) Genomic Organization of Plant Terpene Synthases and Molecular Evolutionary Implications. Genetics 158, 811-832.  http://www.genetics.org/cgi/content/abstract/158/2/811

Vujanovic V and St-Arnaud M (2001) First report of Cryptocline taxicola infecting Pacific yew (Taxus brevifolia) in eastern North America. Plant disease. 85, 922.

Walker K and Croteau R (2001) Taxol biosynthetic genes. Phytochemistry 58, 1-7.  http://www.sciencedirect.com/science/article/pii/S0031942201001601

Wang C, Wu J and Mei X (2001) Enhanced Taxol Production and Release in Taxus chinensisCell Suspension Cultures with Selected Organic Solvents and Sucrose Feeding. Biotechnology Progress 17, 89-94.  http://dx.doi.org/10.1021/bp0001359

Wilson CR, Sauer J-M and Hooser SB (2001) Taxines: a review of the mechanism and toxicity of yew (Taxus spp.) alkaloids. Toxicon 39, 175-185.  http://www.sciencedirect.com/science/article/pii/S004101010000146X

Wink M (2001) Evolution of Secondary Plant Metabolism. In ‘eLS’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470015902.a0001922.pub2

Yamada Y, Shirao K, Ohtsu A, Boku N, Hyodo I, Saitoh H, Miyata Y and Taguchi T (2001) Phase II trial of paclitaxel by three-hour infusion for advanced gastric cancer with short premedication for prophylaxis against paclitaxel-associated hypersensitivity reactions. Ann. Onc. 12, 1133-1137.  http://annonc.oxfordjournals.org/cgi/content/abstract/12/8/1133

Yu L-J, Lan W-Z, Qin W-M and Xu H-B (2001) Effects of salicylic acid on fungal elicitor-induced membrane-lipid peroxidation and taxol production in cell suspension cultures of Taxus chinensis. Process Biochemistry 37, 477-482.  http://www.sciencedirect.com/science/article/pii/S0032959201002436

Anderson ED and Owens JN (2000) Microsporogenesis, Pollination, Pollen Germination and Male Gametophyte Development in Taxus brevifolia. Annals of Botany 86, 1033-1042.  http://www.sciencedirect.com/science/article/pii/S0305736400912745

Badisa RB, Chaudhuri SK, Pilarinou E, Rutkoski NJ, Hare J and Levenson CW (2000) Licania michauxii Prance root extract induces hsp 70 mRNA and necrotic cell death in cultured human hepatoma and colon carcinoma cell lines. Cancer Letters 149, 61-68.  http://www.sciencedirect.com/science/article/pii/S030438359900347X

Bellmunt J, Guillem V, Paz-Ares L, González-Larriba JL, Carles J, Albanell J, Tabernero JM, Cortés-Funes H and Baselga J (2000) Gemcitabine/paclitaxel-based three-drug regimens in advanced urothelial cancer. European Journal of Cancer 36, Supplement 2, 17-25.  http://www.sciencedirect.com/science/article/pii/S0959804900000812

Bohlmann J, Gershenzon J and Aubourg S (2000) Chapter Five Biochemical, molecular, genetic and evolutionary aspects of defense-related terpenoid metabolism in conifers. In ‘Recent Advances in Phytochemistry’ (Ed.^(Eds John T. Romeo RILV and Vincenzo De L) pp. 109-150. (Elsevier). http://www.sciencedirect.com/science/article/pii/S0079992000800064

Caruso M, Colombo AL, Fedeli L, Pavesi A, Quaroni S, Saracchi M and Ventrella G (2000) Isolation of endophytic fungi and actinomycetes taxane producers. Annals of microbiology., 1.  http://www.annmicro.unimi.it/

Ceruti M, Crosasso P, Brusa P, Arpicco S, Dosio F and Cattel L (2000) Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing water-soluble prodrugs of paclitaxel. Journal of Controlled Release 63, 141-153.  http://www.sciencedirect.com/science/article/pii/S0168365999001984

Cheng CC and Gordon MA (2000) An interesting observation of the position of some electronegative atoms in the taxol molecule. Medical Hypotheses 54, 172-176.  http://www.sciencedirect.com/science/article/pii/S0306987799900105

Cheng Y, Nicolson RG, Tripp K and Chaw S-M (2000) Phylogeny of Taxaceae and Cephalotaxaceae Genera Inferred from Chloroplast matK Gene and Nuclear rDNA ITS Region. Molecular Phylogenetics and Evolution 14, 353-365.  http://www.sciencedirect.com/science/article/pii/S1055790399907108

Chu CY, Yang CH, Yang CY, Hsiao GH and Chiu HC (2000) Fixed erythrodysaesthesia plaque due to intravenous injection of docetaxel. British Journal of Dermatology 142, 808-811.  http://dx.doi.org/10.1046/j.1365-2133.2000.03432.x

Crosasso P, Ceruti M, Brusa P, Arpicco S, Dosio F and Cattel L (2000) Preparation, characterization and properties of sterically stabilized paclitaxel-containing liposomes. Journal of Controlled Release 63, 19-30.  http://www.sciencedirect.com/science/article/pii/S0168365999001662

Doyle TW and Vyas DM (2000) Chemotherapeutics, Anticancer. In ‘Kirk-Othmer Encyclopedia of Chemical Technology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471238961.0308051304152512.a01

Hansen EM, Goheen DJ, Jules ES and Ullian B (2000) Managing Port-Orford-cedar and the introduced pathogen Phytophthora lateralis. Plant disease. 84, 4-14.

Herdeg C, Oberhoff M, Baumbach A, Blattner A, Axel DI, Schröder S, Heinle H and Karsch KR (2000) Local paclitaxel delivery for the prevention of restenosis: biological effects and efficacy in vivo. Journal of the American College of Cardiology 35, 1969-1976.  http://www.sciencedirect.com/science/article/pii/S0735109700006148

Hu GW, Ma Z, Wen TY and Yuan YJ (2000) [Cloning of taxadiene synthase cDNA from the cell line of Taxus cuspidata]. Sheng Wu Gong Cheng Xue Bao 16, 158-60.

Huang C-M, Wu Y-T and Chen S-T (2000) Targeting delivery of paclitaxel into tumor cells via somatostatin receptor endocytosis. Chemistry &amp; Biology 7, 453-461.  http://www.sciencedirect.com/science/article/pii/S1074552100001319

Ishii H, Reynolds JH, Ford ED and Shaw DC (2000) Height growth and vertical development of an old-growth Pseudotsuga-Tsuga forest in southwestern Washington State, U.S.A. Canadian journal of forest research. 30, 17-24.

Khattab J, Terebelo HR and Dabas B (2000) Phantom Limb Pain as a Manifestation of Paclitaxel Neurotoxicity. Mayo Clinic Proceedings 75, 740-742.  http://www.sciencedirect.com/science/article/pii/S0025619611646223

Kleemann A (2000) Antineoplastic Agents, 1. Nonhormonal. In ‘Ullmann’s Encyclopedia of Industrial Chemistry’ (Ed.^(Eds  pp. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/14356007.a05_001.pub2

Laskaris G, van der Heijden R and Verpoorte R (2000) Purification and partial characterisation of geranylgeranyl diphosphate synthase, from Taxus baccata cell cultures: An enzyme that regulates taxane biosynthesis. Plant Science 153, 97-105.  http://www.sciencedirect.com/science/article/pii/S0168945299002630

Leung SYL, Jackson J, Miyake H, Burt H and Gleave ME (2000) Polymeric micellar paclitaxel phosphorylates Bcl-2 and induces apoptotic regression of androgen-independent LNCaP prostate tumors. The Prostate 44, 156-163.  http://dx.doi.org/10.1002/1097-0045(20000701)44:2<156::AID-PROS8>3.0.CO;2-8

Lin S, Geng X, Qu C, Tynebor R, Gallagher DJ, Pollina E, Rutter J and Ojima I (2000) Synthesis of highly potent second-generation taxoids through effective kinetic resolution coupling of racemic β-lactams with baccatins. Chirality 12, 431-441.  http://dx.doi.org/10.1002/(SICI)1520-636X(2000)12:5/6<431::AID-CHIR24>3.0.CO;2-M

Mans DRA, da Rocha AB and Schwartsmann G (2000) Anti-Cancer Drug Discovery and Development in Brazil: Targeted Plant Collection as a Rational Strategy to Acquire Candidate Anti-Cancer Compounds. Oncologist 5, 185-198.  http://theoncologist.alphamedpress.org/cgi/content/abstract/5/3/185

Mascavage LM, Jasmin S, Sonnet PE, Wilson M and Dalton DR (2000) Alkaloids. In ‘Ullmann’s Encyclopedia of Industrial Chemistry’ (Ed.^(Eds  pp. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/14356007.a01_353.pub2

Mroczek T, Głowniak K and Hajnos M (2000) Screening for pharmaceutically important taxoids in Taxus baccata var. Aurea Corr. with CC/SPE/HPLC-PDA procedure. Biomedical Chromatography 14, 516-529.  http://dx.doi.org/10.1002/1099-0801(200012)14:8<516::AID-BMC15>3.0.CO;2-9

Nathan FE, Berd D, Sato T and Mastrangelo MJ (2000) Paclitaxel and tamoxifen. Cancer 88, 79-87.  http://dx.doi.org/10.1002/(SICI)1097-0142(20000101)88:1<79::AID-CNCR12>3.0.CO;2-L

Patel RN, Banerjee A and Nanduri V (2000) Enzymatic acetylation of 10-deacetylbaccatin III to baccatin III by C-10 deacetylase from Nocardioides luteus SC 13913. Enzyme and Microbial Technology 27, 371-375.  http://www.sciencedirect.com/science/article/pii/S0141022900002350

Pedroso MC and Durzan DJ (2000) Effect of Different Gravity Environments on DNA Fragmentation and Cell Death in Kalanchoe Leaves. Ann. Bot. 86, 983-994.  http://aob.oxfordjournals.org/cgi/content/abstract/86/5/983

Pedroso MC, Magalhaes JR and Durzan D (2000) Nitric oxide induces cell death in Taxus cells. Plant Science 157, 173-180.  http://www.sciencedirect.com/science/article/pii/S0168945200002788

Pedroso MC, Magalhaes JR and Durzan D (2000) A nitric oxide burst precedes apoptosis in angiosperm and gymnosperm callus cells and foliar tissues. J. Exp. Bot. 51, 1027-1036.  http://jxb.oxfordjournals.org/cgi/content/abstract/51/347/1027

Rinehart KL (2000) Antitumor compounds from tunicates. Medicinal Research Reviews 20, 1-27.  http://dx.doi.org/10.1002/(SICI)1098-1128(200001)20:1<1::AID-MED1>3.0.CO;2-A

Rozendaal ELMv, Lelyveld GP and Beek TAv (2000) Screening of the needles of different yew species and cultivars for paclitaxel and related taxoids. Phytochemistry. 53, 383-389.

Schellen A, Ooms B, Gils Mv, Halmingh O, Vlis Evd, Lagemaat Dvd and Verheij E (2000) High throughput on-line solid phase extraction/tandem mass spectrometric determination of paclitaxel in human serum. Rapid Communications in Mass Spectrometry 14, 230-233.  http://dx.doi.org/10.1002/(SICI)1097-0231(20000229)14:4<230::AID-RCM872>3.0.CO;2-J

Schulte M, Britsch L and Strube J (2000) Continuous preparative liquid chromatography in the downstrem processing of biotechnological products. Acta Biotechnologica 20, 3-15.  http://dx.doi.org/10.1002/abio.370200102

Schwartsmann G (2000) Marine organisms and other novel natural sources of new cancer drugs. Ann. Onc. 11, 235-243.  http://annonc.oxfordjournals.org

Sell CS (2000) Terpenoids. In ‘Kirk-Othmer Encyclopedia of Chemical Technology’ (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471238961.2005181602120504.a01.pub2

Sottani C, Turci R, Micoli G, Fiorentino ML and Minoia C (2000) Rapid and sensitive determination of paclitaxel (Taxol®) in environmental samples by high-performance liquid chromatography tandem mass spectrometry. Rapid Communications in Mass Spectrometry 14, 930-935.  http://dx.doi.org/10.1002/(SICI)1097-0231(20000530)14:10<930::AID-RCM968>3.0.CO;2-4

van Rozendaal ELM, Lelyveld GP and van Beek TA (2000) Screening of the needles of different yew species and cultivars for paclitaxel and related taxoids. Phytochemistry 53, 383-389.  http://www.sciencedirect.com/science/article/pii/S0031942299000941

Wang J, Li G, Lu H, Zheng Z, Huang Y and Su W (2000) Taxol from Tubercularia sp. strain TF5, an endophytic fungus of Taxus mairei. FEMS Microbiology Letters 193, 249-253.  http://www.sciencedirect.com/science/article/pii/S0378109700004912

Watanabe K, Tsuchiyah Y, Kobayashi T and Doi Y (2000) Adaptations of potential ecological significance to Pestalotiopsis neglecta. Mycological Research 104, 686-690.  http://www.sciencedirect.com/science/article/pii/S0953756208603676

Williams DC, Carroll BJ, Jin Q, Rithner CD, Lenger SR, Floss HG, Coates RM, Williams RM and Croteau R (2000) Intramolecular proton transfer in the cyclization of geranylgeranyl diphosphate to the taxadiene precursor of taxol catalyzed by recombinant taxadiene synthase. Chemistry &amp; Biology 7, 969-977.  http://www.sciencedirect.com/science/article/pii/S1074552100000466

Williams DC, Wildung MR, Jin AQ, Dalal D, Oliver JS, Coates RM and Croteau R (2000) Heterologous expression and characterization of a “pseudomature” form of taxadiene synthase involved in paclitaxel (Taxol) biosynthesis and evaluation of a potential intermediate and inhibitors of the multistep diterpene cyclization reaction. Archives of biochemistry and biophysics. 379, 137-146.

Zhang J, Sauriol F, Mamer O and Zamir LO (2000) Taxoids from the needles of the Canadian yew. Phytochemistry 54, 221-230.  http://www.sciencedirect.com/science/article/pii/S0031942200000790

Zong Z-p, Fujikawa-Yamamoto K, Li A-l, Yamaguchi N, Chang Y-g, Murakami M and Ishikawa Y (2000) Involvement of protein kinase C in taxol-induced polyploidization in a cultured sarcoma cell line. European Journal of Pharmacology 394, 181-187.  http://www.sciencedirect.com/science/article/pii/S0014299900001552

Alonso DF, Farina HG, Arregui C, Aon MA and Gomez DE (1999) Modulation of urokinase-type plasminogen activator and metalloproteinase activities in cultured mouse mammary-carcinoma cells: Enhancement by paclitaxel and inhibition by nocodazole. International Journal of Cancer 83, 242-246.  http://dx.doi.org/10.1002/(SICI)1097-0215(19991008)83:2<242::AID-IJC16>3.0.CO;2-8

Anderson ED and Owens JN (1999) Megagametophyte development, fertilization, and cytoplasmic inheritance in Taxus brevifolia. International journal of plant sciences. 160, 459-469.

Baloglu E and Kingston DGI (1999) A new semisynthesis of paclitaxel from baccatin III. [Erratum: Aug 1999, v. 62 (8), p. 1214.]. Journal of natural products. 62, 1068-1071.

Baumann H, Martin RE and Diederich F (1999) PM3 geometry optimization and CNDO/S-CI computation of UV/Vis spectra of large organic structures: Program description and application to poly(triacetylene) hexamer and taxotere. Journal of Computational Chemistry 20, 396-411.  http://dx.doi.org/10.1002/(SICI)1096-987X(199903)20:4<396::AID-JCC2>3.0.CO;2-9

Baumbach A, Herdeg C, Kluge M, Oberhoff M, Lerch M, Haase KK, Wolter C, Schröder S and Karsch KR (1999) Local drug delivery: Impact of pressure, substance characteristics, and stenting on drug transfer into the arterial wall. Catheterization and Cardiovascular Interventions 47, 102-106.  http://dx.doi.org/10.1002/(SICI)1522-726X(199905)47:1<102::AID-CCD22>3.0.CO;2-G

Bernsdorff C, Reszka R and Winter R (1999) Interaction of the anticancer agent Taxol™ (paclitaxel) with phospholipid bilayers. Journal of Biomedical Materials Research 46, 141-149.  http://dx.doi.org/10.1002/(SICI)1097-4636(199908)46:2<141::AID-JBM2>3.0.CO;2-U

Blaghen M, Lahlou N, Dzairi FZ, Moutaouakkil A and Talbi M (1999) Complexation and ionophoric properties of taxol and colchicine: complex formation and transport of sodium, potassium, magnesium and calcium ions across a liquid membrane. Natural Toxins 7, 179-185.  http://dx.doi.org/10.1002/1522-7189(200009/10)7:5<179::AID-NT57>3.0.CO;2-#

Boge TC, Wu Z-J, Himes RH, Vander Velde DG and Georg GI (1999) Conformationally restricted paclitaxel analogues: Macrocyclic mimics of the “hydrophobic collapse” conformation. Bioorganic &amp; Medicinal Chemistry Letters 9, 3047-3052.  http://www.sciencedirect.com/science/article/pii/S0960894X99005223

Borowski P, Kuehl R, Mueller O, Hwang L-H, Schulze zur Wiesch J and Schmitz H (1999) Biochemical properties of a minimal functional domain with ATP-binding activity of the NTPase/helicase of hepatitis C virus. European Journal of Biochemistry 266, 715-723.  http://dx.doi.org/10.1046/j.1432-1327.1999.00854.x

Cabral F, Trimble E, Reed E and Sarosy G (1999) FUTURE DIRECTIONS WITH TAXANE THERAPY. Hematology/Oncology Clinics of North America 13, 21-41.  http://www.sciencedirect.com/science/article/pii/S0889858805701520

Cass BJ, Scott DS and Legge RL (1999) Determination of taxane concentrations in Taxus canadensis clippings using high performance liquid chromatographic analysis with an internal standard. Phytochemical Analysis 10, 88-92.  http://dx.doi.org/10.1002/(SICI)1099-1565(199903/04)10:2<88::AID-PCA440>3.0.CO;2-Q

Cortesi R and Nastruzzi C (1999) Liposomes, micelles and microemulsions as new delivery systems for cytotoxic alkaloids. Pharmaceutical Science &amp; Technology Today 2, 288-298.  http://www.sciencedirect.com/science/article/pii/S1461534799001716

Curtis-Prior P, Vere D and Fray P (1999) Therapeutic Value of Ginkgo biloba in Reducing Symptoms of Decline in Mental Function. Journal of Pharmacy and Pharmacology 51, 535-541.  http://dx.doi.org/10.1211/0022357991772817

Cusidó RM, Palazón J, Navia-Osorio A, Mallol A, Bonfill M, Morales C and Pińol MT (1999) Production of Taxol® and baccatin III by a selected Taxus baccata callus line and its derived cell suspension culture. Plant Science 146, 101-107.  http://www.sciencedirect.com/science/article/pii/S016894529900093X

Dawson IK and Powell W (1999) Genetic variation in the Afromontane tree Prunus africana, an endangered medicinal species. Molecular Ecology 8, 151-156.  http://dx.doi.org/10.1046/j.1365-294X.1999.00518.x

Digue L, Orsičre T, De Méo M, Mattéi MG, Depetris D, Duffaud F, Favre R and Botta A (1999) Evaluation of the genotoxic activity of paclitaxel by the in vitro micronucleus test in combination with fluorescent in situ hybridization of a DNA centromeric probe and the alkaline single cell gel electrophoresis technique (comet assay) in human T-lymphocytes. Environmental and Molecular Mutagenesis 34, 269-278.  http://dx.doi.org/10.1002/(SICI)1098-2280(1999)34:4<269::AID-EM7>3.0.CO;2-D

Dutta D, Hadd H, Vander Velde DG and Georg GI (1999) A one-step synthesis of a deuterated paclitaxel analogue: 10-Deacetoxy-(10α-2H)paclitaxel. Bioorganic &amp; Medicinal Chemistry Letters 9, 3277-3278.  http://www.sciencedirect.com/science/article/pii/S0960894X99006095

Fuchs J, Habild G, Leuschner I, Schweinitz DV, Haindl J and Knop E (1999) Paclitaxel: An effective antineoplastic agent in the treatment of xenotransplanted hepatoblastoma. Medical and Pediatric Oncology 32, 209-215.  http://dx.doi.org/10.1002/(SICI)1096-911X(199903)32:3<209::AID-MPO8>3.0.CO;2-0

Gagandeep S, Novikoff PM, Ott M and Gupta S (1999) Paclitaxel shows cytotoxic activity in human hepatocellular carcinoma cell lines. Cancer Letters 136, 109-118.  http://www.sciencedirect.com/science/article/pii/S0304383598003887

Glowniak K, Mroczek T and Zobel AM (1999) Seasonal changes in the concentrations of four taxoids in Taxus baccata L. during the autumn-spring period. Phytomedicine 6, 135-140.  http://www.sciencedirect.com/science/article/pii/S094471139980049X

Hicock SR, Lian OB and Mathewes RW (1999) ‘Bond cycles’ recorded in terrestrial Pleistocene sediments of southwestern British Columbia, Canada. Journal of Quaternary Science 14, 443-449.  http://dx.doi.org/10.1002/(SICI)1099-1417(199908)14:5<443::AID-JQS459>3.0.CO;2-6

Hook I, Poupat C, et al. (1999) Seasonal variation of neutral and basic taxoid contents in shoots of European Yew (Taxus baccata). Phytochemistry 52, 1041-1045.  http://www.sciencedirect.com/science/article/pii/S0031942299002642

Kang Min H, Figg William D and Dahut W (1999) Taxanes in Hormone-Refractory Prostate Cancer. Cancer Practice 7, 270-272.  http://dx.doi.org/10.1046/j.1523-5394.1999.75005.x

Kapoor P and Rmadhubala MS (1999) Effect of the microtubule stabilising agent taxol on leishmanial protozoan parasites in vitro. FEMS Microbiology Letters 176, 429-435.  http://dx.doi.org/10.1111/j.1574-6968.1999.tb13693.x

Ketchum REB, Gibson DM, Croteau RB and Shuler ML (1999) The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate. Biotechnology and Bioengineering 62, 97-105.  http://dx.doi.org/10.1002/(SICI)1097-0290(19990105)62:1<97::AID-BIT11>3.0.CO;2-C

Ketchum REB, Luong JV and Gibson DM (1999) Efficient extraction of paclitaxel and related taxoids from leaf tissue of Taxus using a potable solvent system. Journal of liquid chromatography & related technologies., 11.

Kim YH, Shin SW, et al. (1999) Paclitaxel, 5-fluorouracil, and cisplatin combination chemotherapy for the treatment of advanced gastric carcinoma. Cancer 85, 295-301.  http://dx.doi.org/10.1002/(SICI)1097-0142(19990115)85:2<295::AID-CNCR5>3.0.CO;2-H

Kudelka, Verschraegen, et al. (1999) Long-term results and pharmacokinetics of high-dose paclitaxel in patients with refractory epithelial ovarian carcinoma. International Journal of Gynecological Cancer 9, 44-53.  http://dx.doi.org/10.1046/j.1525-1438.1999.09856.x

Laskaris G, Bounkhay M, Theodoridis G, van der Heijden R, Verpoorte R and Jaziri M (1999) Induction of geranylgeranyl diphosphate synthase activity and taxane accumulation in Taxus baccata cell cultures after elicitation by methyl jasmonate. Plant Science 147, 1-8.  http://www.sciencedirect.com/science/article/pii/S0168945299000783

Laskaris G, De Jong CF, Jaziri M, Van Der Heijden R, Theodoridis G and Verpoorte R (1999) Geranylgeranyl diphosphate synthase activity and taxane production in Taxus baccata cells. Phytochemistry 50, 939-946.  http://www.sciencedirect.com/science/article/pii/S0031942298006451

Lee K-H (1999) Novel antitumor agents from higher plants. Medicinal Research Reviews 19, 569-596.  http://dx.doi.org/10.1002/(SICI)1098-1128(199911)19:6<569::AID-MED7>3.0.CO;2-9

Lee MS and Kerns EH (1999) LC/MS applications in drug development. Mass Spectrometry Reviews 18, 187-279.  http://dx.doi.org/10.1002/(SICI)1098-2787(1999)18:3/4<187::AID-MAS2>3.0.CO;2-K

Lee RT, Oster MW, Balmaceda C, Hesdorffer CS, Vahdat LT and Papadopoulos KP (1999) Bilateral facial nerve palsy secondary to the administration of high-dose paclitaxel. Ann. Onc. 10, 1245-1247.  http://annonc.oxfordjournals.org/cgi/content/abstract/10/10/1245

Noh M-J, Yang J-G, Kim K-S, Yoon Y-M, Kang K-A, Han H-Y, Shim S-B and Park H-J (1999) Isolation of a novel microorganism, Pestalotia heterocornis, producing paclitaxel. Biotechnology and Bioengineering 64, 620-623.  http://dx.doi.org/10.1002/(SICI)1097-0290(19990905)64:5<620::AID-BIT13>3.0.CO;2-W

Ojima I, Chakravarty S, Inoue T, Lin S, He L, Horwitz SB, Kuduk SD and Danishefsky SJ (1999) A common pharmacophore for cytotoxic natural products that stabilize microtubules. PNAS 96, 4256-4261.  http://www.pnas.org/cgi/content/abstract/96/8/4256

Panday VRN, Huinink WWTB, Vermorken JB, Rosing H, Koopman FJ, Swart M, Schellens JHM and Beijnen JH (1999) PHARMACOKINETICS OF PACLITAXEL ADMINISTERED AS A 3-HOUR OR 96-HOUR INFUSION. Pharmacological Research 40, 67-74.  http://www.sciencedirect.com/science/article/pii/S1043661899904772

Park YK, Chung ST and Row KH (1999) Preparative chromatographic separation of taxol from Yew trees. Journal of liquid chromatography & related technologies., 18.

Phillipson JD (1999) New drugs from nature—it could be yew. Phytotherapy Research 13, 2-8.  http://dx.doi.org/10.1002/(SICI)1099-1573(199902)13:1<2::AID-PTR471>3.0.CO;2-K

Potemski P and Pluzanska A (1999) [Pharmacological action of paclitaxel]. Pol Merkur Lekarski 6, 27-9.

Pradier O, Rave-Frank M, Schmidberger H, Bomecke M, Lehmann J, Meden H and Hess CF (1999) Effects of paclitaxel in combination with radiation on human head and neck cancer cells (ZMK-1), cervical squamous cell carcinoma (CaSki), and breast adenocarcinoma cells (MCF-7). J Cancer Res Clin Oncol 125, 20-7.

Pucci B, Bellincampi L, Tafani M, Masciullo V, Melino G and Giordano A (1999) Paclitaxel Induces Apoptosis in Saos-2 Cells with CD95L Upregulation and Bcl-2 Phosphorylation. Experimental Cell Research 252, 134-143.  http://www.sciencedirect.com/science/article/pii/S0014482799945913

Russell JR, Weber JC, Booth A, Powell W, Dawson CS-M and I K (1999) Genetic variation of Calycophyllum spruceanum in the Peruvian Amazon Basin, revealed by amplified fragment length polymorphism (AFLP) analysis. Molecular Ecology 8, 199-204.  http://dx.doi.org/10.1046/j.1365-294X.1999.00551.x

Sheppard BC, Rutten MJ, et al. (1999) Effects of paclitaxel on the growth of normal, polyposis, and cancerous human colonic epithelial cells. Cancer 85, 1454-1464.  http://dx.doi.org/10.1002/(SICI)1097-0142(19990401)85:7<1454::AID-CNCR5>3.0.CO;2-#

Song CE, Oh CR, Roh EJ, Lee S-g and Choi JH (1999) One-step synthesis of paclitaxel side-chain precursor: benzamide-based asymmetric aminohydroxylation of isopropyl trans-cinnamate. Tetrahedron: Asymmetry 10, 671-674.  http://www.sciencedirect.com/science/article/pii/S0957416699000403

Stahlhut R, Park G, Petersen R, Ma W and Hylands P (1999) The occurrence of the anti-cancer diterpene taxol in Podocarpus gracilior Pilger (Podocarpaceae). Biochemical Systematics and Ecology 27, 613-622.  http://www.sciencedirect.com/science/article/pii/S0305197898001185

Stierle DB, Stierle AA and Ganser BK (1999) Isolation of two highly methylated polyketide derivatives from a yew-associated penicillium species. J Nat Prod 62, 1147-50.

Strobel GA, Ford E, Li JY, Sears J, Sidhu RS and Hess WM (1999) Seimatoantlerium tepuiense gen. nov., a Unique Epiphytic Fungus Producing Taxol from the Venezuelan Guyana. Systematic and Applied Microbiology 22, 426-433.  http://www.sciencedirect.com/science/article/pii/S0723202099800526

Svenning J-C and Magĺrd E (1999) Population ecology and conservation status of the last natural population of English yew Taxus baccata in Denmark. Biological Conservation 88, 173-182.  http://www.sciencedirect.com/science/article/pii/S0006320798001062

Svojanovsky SR, Egodage KL, Wu J, Slavik M and Wilson GS (1999) High sensitivity ELISA determination of taxol in various human biological fluids. Journal of Pharmaceutical and Biomedical Analysis 20, 549-555.  http://www.sciencedirect.com/science/article/pii/S0731708599000734

Unno T, Komori S and Ohashi H (1999) Microtubule cytoskeleton involvement in muscarinic suppression of voltage-gated calcium channel current in guinea-pig ileal smooth muscle. British Journal of Pharmacology 127, 1703-1711.  http://dx.doi.org/10.1038/sj.bjp.0702711

Veselá D, Šaman D, Valterová I and Vanĕk T (1999) Seasonal variations in the content of taxanes in the bark of Taxus baccata L. Phytochemical Analysis 10, 319-321.  http://dx.doi.org/10.1002/(SICI)1099-1565(199911/12)10:6<319::AID-PCA471>3.0.CO;2-W

Walsh V and Goodman J (1999) Cancer chemotherapy, biodiversity, public and private property: the case of the anti-cancer drug Taxol. Social Science &amp; Medicine 49, 1215-1225.  http://www.sciencedirect.com/science/article/pii/S0277953699001616

Wang HQ, Yu JT and Zhong JJ (1999) Significant improvement of taxane production in suspension cultures of Taxus chinensis by sucrose feeding strategy. Process Biochemistry 35, 479-483.  http://www.sciencedirect.com/science/article/pii/S0032959299000941

Yadav JS and Sasmal PK (1999) Diels-Alder approach towards the stereocontrolled construction of a taxol® C ring fragment. Tetrahedron 55, 5185-5194.  http://www.sciencedirect.com/science/article/pii/S0040402099001659

Zoli W, Ricotti L, Barzanti F, Dal Susino M, Frassineti GL, Milri C, Casadei Giunchi D and Amadori D (1999) Schedule-dependent interaction of doxorubicin, paclitaxel and gemcitabine in human breast cancer cell lines. International Journal of Cancer 80, 413-416.  http://dx.doi.org/10.1002/(SICI)1097-0215(19990129)80:3<413::AID-IJC13>3.0.CO;2-I

(1998) Efficient selection of cells with high taxol content from heterogeneous Taxus cell suspensions by magnetic or fluorescent antibodies: Michio Kawamura1,3, Takeo Shigeoka1, Makoto Tahara2,4, Masamichi Takami2, Hiroaki Ohashi2,5, Motomu Akita1,6, Yoshinori Kobayashi1, Tetsuo Sakamoto2, (Tsukuba Research Laboratories, Kyowa Hakko Kogyo Co. Ltd., 2 Miyukigaoka, Tsukuba, Ibaraki 305-08411; Life Science Research Center, Nippon Steel Corporation, 1618 Ida, Nakahara-ku, Kawasaki, Kanagawa 211-00352) Seibutsu-kogaku 76: 3–7. 1998. Journal of Fermentation and Bioengineering 85, 254.  http://www.sciencedirect.com/science/article/pii/S0922338X97867797

(1998) Studies on the development and application of biocatalyst systems: Monograph— Atsuo Tanaka (Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8317) Seibutsu-kogaku 76: 8–19. 1998. Journal of Fermentation and Bioengineering 85, 254.  http://www.sciencedirect.com/science/article/pii/S0922338X97867803

(1998) Subject index. The Journal of Supercritical Fluids 11, 209-227.  http://www.sciencedirect.com/science/article/pii/S0896844698000825

Al-alami O, Sammons J, Martin JH and Hassan HT (1998) Divergent effect of taxol on proliferation, apoptosis and nitric oxide production in MHH225 CD34 positive and U937 CD34 negative human leukaemia cells. Leukemia Research 22, 939-945.  http://www.sciencedirect.com/science/article/pii/S0145212698000927

Barnes J (1998) Medicinal natural products. Focus on Alternative and Complementary Therapies 3, 78-78.  http://dx.doi.org/10.1111/j.2042-7166.1998.tb00828.x

Bicamumpaka C and Pagé M (1998) Development of a fluorescence polarization immunoassay (FPIA) for the quantitative determination of paclitaxel. Journal of Immunological Methods 212, 1-7.  http://www.sciencedirect.com/science/article/pii/S002217599700183X

Bignami GS and Mooberry SL (1998) Monoclonal antibodies to taxanes that neutralize the biological activity of paclitaxel. Cancer Letters 126, 127-133.  http://www.sciencedirect.com/science/article/pii/S0304383597005065

Chu J-J, Chen K-D, Lin Y-L, Fei C-Y, Chiang A-S, Chiang C-D and Lai Y-K (1998) Taxol induces concomitant hyperphosphorylation and reorganization of vimentin intermediate filaments in 9l rat brain tumor cells. Journal of Cellular Biochemistry 68, 472-483.  http://dx.doi.org/10.1002/(SICI)1097-4644(19980315)68:4<472::AID-JCB7>3.0.CO;2-N

Cragg GM (1998) Paclitaxel (Taxol®): A success story with valuable lessons for natural product drug discovery and development. Medicinal Research Reviews 18, 315-331.  http://dx.doi.org/10.1002/(SICI)1098-1128(199809)18:5<315::AID-MED3>3.0.CO;2-W

Damen EWP, Braamer L and Scheeren HW (1998) Lanthanide trifluoromethanesulfonate catalysed selective acylation of 10-deacetylbaccatin III. Tetrahedron Letters 39, 6081-6082.  http://www.sciencedirect.com/science/article/pii/S0040403998012532

de Vos AI, Nooter K, et al. (1998) Tubulin interacting agents

Differential modulation of cisplatin accumulation in leukocytes and tumor cell lines by the paclitaxel vehicle Cremophor EL. Ann. Onc. 9, 90-104.  http://annonc.oxfordjournals.org http://annonc.oxfordjournals.org/cgi/content/abstract/8/11/1145

Desai A and Mitchison TJ (1998) Tubulin and FtsZ structures: functional and therapeutic implications. BioEssays 20, 523-527.  http://dx.doi.org/10.1002/(SICI)1521-1878(199807)20:7<523::AID-BIES1>3.0.CO;2-L

DiFazio SP, Wilson MV and Vance NC (1998) Factors limiting seed production of Taxus brevifolia (Taxaceae) in Western Oregon. Am. J. Botany 85, 910-.  http://www.amjbot.org/cgi/content/abstract/85/7/910

Durzan DJ, Ventimiglia F and Havel L (1998) Taxane recovery from cells of taxus in micro- and hypergravity. Acta Astronautica 42, 455-463.  http://www.sciencedirect.com/science/article/pii/S0094576598001386

Forastiere AA, Shank D, Neuberg D, Taylor SG, DeConti RC and Adams G (1998) Final report of a phase II evaluation of paclitaxel in patients with advanced squamous cell carcinoma of the head and neck. Cancer 82, 2270-2274.  http://dx.doi.org/10.1002/(SICI)1097-0142(19980601)82:11<2270::AID-CNCR24>3.0.CO;2-Q

Giannakakou P, Villalba L, Li H, Poruchynsky M and Fojo T (1998) Combinations of pacliataxel and vinblastine and their effects on tublin polymerization and cellular cytotoxicity: Characterization of a synergistic schedule. International Journal of Cancer 75, 57-63.  http://dx.doi.org/10.1002/(SICI)1097-0215(19980105)75:1<57::AID-IJC10>3.0.CO;2-A

Hans-Peter M (1998) Use of plant cell cultures in biotechnology. In ‘Biotechnology Annual Review’ (Ed.^(Eds El-Gewely MR) pp. 113-176. (Elsevier). http://www.sciencedirect.com/science/article/pii/S1387265608700693

Huang K-x, Huang Q-l, Wildung MR, Croteau R and Scott AI (1998) Overproduction, inEscherichia coli,of Soluble Taxadiene Synthase, a Key Enzyme in the Taxol Biosynthetic Pathway. Protein Expression and Purification 13, 90-96.  http://www.sciencedirect.com/science/article/pii/S1046592898908701

Hui A, Min WX, Tang J and Cruz TF (1998) Inhibition of activator protein 1 activity by paclitaxel suppresses interleukin-1-induced collagenase and stromelysin expression by bovine chondrocytes. Arthritis & Rheumatism 41, 869-876.  http://dx.doi.org/10.1002/1529-0131(199805)41:5<869::AID-ART15>3.0.CO;2-3

Jaquish B and El-Kassaby Y (1998) Genetic variation of western larch in British Columbia and its conservation. J. Hered. 89, 248-253.  http://jhered.oxfordjournals.org/cgi/content/abstract/89/3/248

Kerns EH, Volk KJ, Whitney JL, Rourick RA and Lee MS (1998) Chemical Identification of Botanical Components Using Liquid Chromatography/Mass Spectrometry. Drug Information Journal 32, 471-485.  http://dij.sagepub.com/cgi/content/abstract/32/2/471

Klar U, Graf H, Schenk O, Röhr B and Schulz H (1998) New synthetic inhibitors of microtubule depolymerization. Bioorganic &amp; Medicinal Chemistry Letters 8, 1397-1402.  http://www.sciencedirect.com/science/article/pii/S0960894X98002261

Krutovskii K, Vollmer S, Sorensen F, Adams W, Knapp S and Strauss S (1998) RAPD Genome maps of Douglas-fir. J. Hered. 89, 197-205.  http://jhered.oxfordjournals.org/cgi/content/abstract/89/3/197

Kwon IC, Yoo YJ, Lee JH and Hyun JO (1998) Enhancement of taxol production by in situ recovery of product. Process Biochemistry 33, 701-707.  http://www.sciencedirect.com/science/article/pii/S0032959298000375

Lee D, Kim K-C and Kim M-J (1998) Selective enzymatic acylation of 10-Deacetylbaccatin III. Tetrahedron Letters 39, 9039-9042.  http://www.sciencedirect.com/science/article/pii/S0040403998020498

Li J-Y, Sidhu RS, Bollon A and Strobel GA (1998) Stimulation of taxol production in liquid cultures of Pestalotiopsis microspora. Mycological Research 102, 461-464.  http://www.sciencedirect.com/science/article/pii/S0953756208609004

Ling Y-H, Consoli U, Tornos C, Andreeff M and Perez-Soler R (1998) Accumulation of cyclin B1, activation of cyclin B1-dependent kinase and induction of programmed cell death in human epidermoid carcinoma KB cells treated with taxol. International Journal of Cancer 75, 925-932.  http://dx.doi.org/10.1002/(SICI)1097-0215(19980316)75:6<925::AID-IJC16>3.0.CO;2-1

Liu Z, Carpenter SB, Bourgeois WJ, Yu Y, Constantin RJ, Falcon MJ and Adams JC (1998) Variations in the secondary metabolite camptothecin in relation to tissue age and season in Camptotheca acuminata. Tree Physiol 18, 265-270.  http://treephys.oxfordjournals.org/cgi/content/abstract/18/4/265

Marshall VG, Clayton MR and Newsom DN (1998) Morphology, ontogeny, and intraspecific variability of the new big bud mite, Cecidophyopsis psilaspis (Acari: Eriophyidae). Canadian entomologist. 130, 285-304.

Mitchell AK (1998) Acclimation of Pacific yew (Taxus brevifolia) foliage to sun and shade. Tree Physiol 18, 749-757.  http://treephys.oxfordjournals.org/cgi/content/abstract/18/11/749

Mross K, Hauns B, Hring B, Bauknecht T, Meerpohl HG, Unger C and Maier-Lenz H (1998) Clinical phase I study with one-hour paclitaxel infusion. Ann. Onc. 9, 569-572.  http://annonc.oxfordjournals.org/cgi/content/abstract/9/5/569

Nalesnik CA, Hansen BN and Hsu JT (1998) Solubility of pure taxol in supercritical carbon dioxide. Fluid Phase Equilibria 146, 315-323.  http://www.sciencedirect.com/science/article/pii/S0378381298002209

Nathan FE and Mastrangelo MJ (1998) Systemic therapy in melanoma. Seminars in Surgical Oncology 14, 319-327.  http://dx.doi.org/10.1002/(SICI)1098-2388(199806)14:4<319::AID-SSU8>3.0.CO;2-5

O’Leary J, Volm M, Wasserheit C and Muggia F (1998) Taxanes in adjuvant and neoadjuvant therapies for breast cancer. Oncology (Williston Park) 12, 23-7.

Pandey RC (1998) Prospecting for potentially new pharmaceuticals from natural sources. Medicinal Research Reviews 18, 333-346.  http://dx.doi.org/10.1002/(SICI)1098-1128(199809)18:5<333::AID-MED4>3.0.CO;2-U

Ramesh P (1998) Pharmaceutical aspects of paclitaxel. International Journal of Pharmaceutics 172, 1-15.  http://www.sciencedirect.com/science/article/pii/S0378517398001884

Rao KV and Juchum J (1998) Taxanes from the bark of Taxus brevifolia. Phytochemistry 47, 1315-1324.  http://www.sciencedirect.com/science/article/pii/S003194229700722X

Schwartz GN, Pendyala L, Kindler H, Meropol N, Perez R, Raghavan D and Creaven P (1998) The clinical development of paclitaxel and the paclitaxel/carboplatin combination. European Journal of Cancer 34, 1543-1548.  http://www.sciencedirect.com/science/article/pii/S0959804998002251

Simizu S, Tanabe K, Tashiro E, Takada M, Umezawa K and Imoto M (1998) Potentiation of Paclitaxel Cytotoxicity by Inostamycin in Human Small Cell Lung Carcinoma, Ms-1 Cells. Cancer Science 89, 970-976.  http://dx.doi.org/10.1111/j.1349-7006.1998.tb00656.x

Song CE, Lee SW, Roh EJ, Lee S-g and Lee W-K (1998) A new synthetic route to (3R,4S)-3-hydroxy-4-phenylazetidin-2-one as a taxol side chain precursor. Tetrahedron: Asymmetry 9, 983-992.  http://www.sciencedirect.com/science/article/pii/S0957416698000494

Sottani C, Minoia C, D’Incalci M, Paganini M and Zucchetti M (1998) High-performance liquid chromatography tandem mass spectrometry procedure with automated solid phase extraction sample preparation for the quantitative determination of paclitaxel (Taxol®) in human plasma. Rapid Communications in Mass Spectrometry 12, 251-255.  http://dx.doi.org/10.1002/(SICI)1097-0231(19980314)12:5<251::AID-RCM145>3.0.CO;2-Z

Stierle DB, Stierle AA and Kunz A (1998) Dihydroramulosin from Botrytis sp. J Nat Prod 61, 1277-8.

Teodora K (1998) Activity of lysosomal system in mouse liver after taxol administration. General Pharmacology: The Vascular System 30, 239-243.  http://www.sciencedirect.com/science/article/pii/S0306362397000918

Wall ME (1998) Camptothecin and taxol: discovery to clinic. Med Res Rev 18, 299-314.

Bailey JD and Liegel LH (1997) Response of Pacific yew (Taxus brevifolia) to partial removal of the overstory. Western journal of applied forestry. 12, 41-43.

Bookman MA, Kloth DD, Kover PE, Smolinski S and Ozols RF (1997) Short-course intravenous prophylaxis for paclitaxel-related hypersensitivity reactions. Ann. Onc. 8, 611-614.  http://annonc.oxfordjournals.org/cgi/content/abstract/8/6/611

Callaini G and Riparbelli MG (1997) Patterns of microtubule assembly in taxol-treated early Drosophila embryo. Cell Motility and the Cytoskeleton 37, 300-307.  http://dx.doi.org/10.1002/(SICI)1097-0169(1997)37:4<300::AID-CM2>3.0.CO;2-8

Di Fazio SP, Vance NC and Wilson MV (1997) Strobilus production and growth of Pacific yew under a range of overstory conditions in western Oregon. Canadian journal of forest research. 27, 986-993.

Distefano M, Scambia G, et al. (1997) Anti-proliferative activity of a new class of taxanes (14β-hydroxy-10-deacetylbaccatin III derivatives) on multidrug-resistance-positive human cancer cells. International Journal of Cancer 72, 844-850.  http://dx.doi.org/10.1002/(SICI)1097-0215(19970904)72:5<844::AID-IJC22>3.0.CO;2-7

Dorr RT (1997) Pharmacology of the Taxanes. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 17, 96S-104S.  http://dx.doi.org/10.1002/j.1875-9114.1997.tb03811.x

ElSohly HN, Croom EM, Kopycki WJ, Joshi AS and McChesney JD (1997) Diurnal and Seasonal Effects on the Taxane Content of the Clippings of Certain Taxus Cultivars. Phytochemical Analysis 8, 124-129.  http://dx.doi.org/10.1002/(SICI)1099-1565(199705)8:3<124::AID-PCA342>3.0.CO;2-1

Frasci G, Comella P, Parziale A, Casaretti R, Daponte A, Gravina A, Rosa LD, Gallipoli A and Comella G (1997) Cisplatin-paclitaxel weekly schedule in advanced solid tumors: A phase I study. Ann. Onc. 8, 291-293.  http://annonc.oxfordjournals.org/cgi/content/abstract/8/3/291

Hezari M, Ketchum RE, Gibson DM and Croteau R (1997) Taxol production and taxadiene synthase activity in Taxus canadensis cell suspension cultures. Arch Biochem Biophys 337, 185-90.

Hezari M, Ketchum REB, Gibson DM and Croteau R (1997) Taxol production and taxadiene synthase activity in Taxus canadensis cell suspension cultures. Archives of biochemistry and biophysics. 337, 185-190.

Hui A, Kulkarni GV, Hunter WL, McCulloch CAG and Cruz TF (1997) Paclitaxel selectively induces mitotic arrest and apoptosis in proliferating bovine synoviocytes. Arthritis & Rheumatism 40, 1073-1084.  http://dx.doi.org/10.1002/art.1780400612

Jordan CD and Wells WA (1997) Taxol effect: bizarre mitotic figures (abnormal spindle asters) in a malignant peritoneal effusion: report of a case. Diagn Cytopathol 17, 209-12.

Kubota T, Matsuzaki SW, Hoshiya Y, Watanabe M, Kitajima M, Asanuma F, Yamada Y and Koh J-I (1997) Antitumor activity of paclitaxel against human breast carcinoma xenografts serially transplanted into nude mice. Journal of Surgical Oncology 64, 115-121.  http://dx.doi.org/10.1002/(SICI)1096-9098(199702)64:2<115::AID-JSO5>3.0.CO;2-E

Lundberg BB (1997) A Submicron Lipid Emulsion Coated with Amphipathic Polyethylene Glycol for Parenteral Administration of Paclitaxel (Taxol). Journal of Pharmacy and Pharmacology 49, 16-21.  http://dx.doi.org/10.1111/j.2042-7158.1997.tb06744.x

Mitchell AK (1997) Propagation and growth of Pacific yew (Taxus brevifolia Nutt.) cuttings. Northwest science. 71, 56-63.

Mitchell AK, Duncan RW, Bown TA and Marshall VG (1997) Origin and distribution of the yew big bud mite, Cecidophyopsis psilaspis (Nalepa), in British Columbia. Canadian entomologist. 129, 745-755.

Murray MS and Hansen EM (1997) Susceptibility of Pacific yew to Phytophthora lateralis. Plant disease. 81, 1400-1404.

Nativ O, Aronson M, Medalia O, Moldavsky T, Sabo E, Ringel I and Kravtsov V (1997) Anti-neoplastic activity of paclitaxel on experimental superficial bladder cancer: In vivo and in vitro studies. International Journal of Cancer 70, 297-301.  http://dx.doi.org/10.1002/(SICI)1097-0215(19970127)70:3<297::AID-IJC9>3.0.CO;2-S

O’Boyle KP, Wang Y, Schwartz EL, Regl DL, Einzig A, Dutcher JP, Wiernik PH and Horwitz SB (1997) Development of two radioimmunoassays to detect paclitaxel in sera and in cerebrospinal, ascitic, and pleural fluids. Cancer 79, 1022-1030.  http://dx.doi.org/10.1002/(SICI)1097-0142(19970301)79:5<1022::AID-CNCR20>3.0.CO;2-2

Ojima I and Slater JC (1997) Synthesis of novel 3′-trifluoromethyl taxoids through effective kinetic resolution of racemic 4-CF3-β-lactams with baccatins. Chirality 9, 487-494.  http://dx.doi.org/10.1002/(SICI)1520-636X(1997)9:5/6<487::AID-CHIR15>3.0.CO;2-K

Pulici M, Sugawara F, Koshino H, Okada G, Esumi Y, Uzawa J and Yoshida S (1997) Metabolites of Pestalotiopsis spp., endophytic fungi of Taxus brevifolia. Phytochemistry. 46, 313-319.

Rao KV (1997) Semi-synthesis of paclitaxel from naturally occurring glycosidic precursors. Journal of Heterocyclic Chemistry 34, 675-680.  http://dx.doi.org/10.1002/jhet.5570340255

Rave-Frank M, Meden H, Jaschke A, Tanzer A, Boghun O and Fietkau R (1997) The effect of paclitaxel on the radiosensitivity of gynecological tumor cells. Strahlenther Onkol 173, 281-6.

Rohr J (1997) Biosynthesis of Taxol. Angewandte Chemie International Edition in English 36, 2190-2195.  http://dx.doi.org/10.1002/anie.199721901

Rohr J (1997) Biosynthese von Taxol. Angewandte Chemie 109, 2284-2289.  http://dx.doi.org/10.1002/ange.19971092008

Scialli AR, Waterhouse TB, Desesso JM, Rahman A and Goeringer GC (1997) Protective effect of liposome encapsulation on paclitaxel developmental toxicity in the rat. Teratology 56, 305-310.  http://dx.doi.org/10.1002/(SICI)1096-9926(199711)56:5<305::AID-TERA3>3.0.CO;2-W

Seki M, Ohzora C, Takeda M and Furusaki S (1997) Taxol (paclitaxel) production using free and immobilized cells of Taxus cuspidata. Biotechnology and Bioengineering 53, 214-219.  http://dx.doi.org/10.1002/(SICI)1097-0290(19970120)53:2<214::AID-BIT12>3.0.CO;2-K

Sottani C, Minoia C, Colombo A, Zucchetti M, D’Incalci M and Fanelli R (1997) Structural characterization of mono- and dihydroxylated metabolites of paclitaxel in rat bile using liquid chromatography/ion spray tandem mass spectrometry. Rapid Communications in Mass Spectrometry 11, 1025-1032.  http://dx.doi.org/10.1002/(SICI)1097-0231(19970615)11:9<1025::AID-RCM956>3.0.CO;2-M

Stierle DB, Stierle AA and Ganser B (1997) New phomopsolides from a Penicillium sp. J Nat Prod 60, 1207-9.

Strobel GA, Hess WM, Li JY, Ford E, Sears J, Sidhu RS and Summerell B (1997) Pestalotiopsis guepinii, a taxol-producing endophyte of the Wollemi pine, Wollemia nobilis. Australian journal of botany., 6.

Terry NHA, Milross CG, Patel N, Mason KA, White RA and Milas L (1997) The Effect of Paclitaxel on the Cell Cycle Kinetics of a Murine Mammary Adenocarcinoma In Vivo. The Breast Journal 3, 99-105.  http://dx.doi.org/10.1111/j.1524-4741.1997.tb00151.x

van Rozendaal ELM, Lelyveld GP and van Beek TA (1997) A simplified method for the determination of taxanes in yew needles by reversed-phase (C18) high pressure liquid chromatography. Phytochemical Analysis 8, 286-293.  http://dx.doi.org/10.1002/(SICI)1099-1565(199711/12)8:6<286::AID-PCA374>3.0.CO;2-G

Wesemann L (1997) The Direct Synthesis of a closo-Borate from Elemental Boron. Angewandte Chemie International Edition in English 36, 2189-2190.  http://dx.doi.org/10.1002/anie.199721891

Wolfson M, Yang C-PH and Horwitz SB (1997) Taxol induces tyrosine phosphorylation of SHC and its association with GRB2 in murine raw 264.7 cells. International Journal of Cancer 70, 248-252.  http://dx.doi.org/10.1002/(SICI)1097-0215(19970117)70:2<248::AID-IJC17>3.0.CO;2-E

Wu DJ, Ma Z, Au BW and Wang NHL (1997) Recovery and purification of paclitaxel using low-pressure liquid chromatography. AIChE Journal 43, 232-242.  http://dx.doi.org/10.1002/aic.690430125

Yamori T, Sato S, Chikazawa H and Kadota T (1997) Anti-tumor Efficacy of Paclitaxel against Human Lung Cancer Xenografts. Cancer Science 88, 1205-1210.  http://dx.doi.org/10.1111/j.1349-7006.1997.tb00350.x

Adelstein EH, Madsen R, Perez-Espejo M-A and Haghighi SS (1996) The effects of taxol, methylprednisolone, and 4-aminopyridine in compressive spinal cord injury: A qualitative experimental study. Surgical Neurology 46, 350-357.  http://www.sciencedirect.com/science/article/pii/S0090301996002005

Andreassen PR, Martineau SN and Margolis RL (1996) Chemical induction of mitotic checkpoint override in mammalian cells results in aneuploidy following a transient tetraploid state. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 372, 181-194.  http://www.sciencedirect.com/science/article/pii/S0027510796001388

Baker SM and White EE (1996) A chalcone synthase stilbene synthase DNA probe for conifers. Theoretical and applied genetics. 92, 827-831.

Bronaugh W (1996) The biggest pacific yew. American forests. 102, 28.

Chang Y-F, Li LL, Wu C-W, Liu T-Y, Lui W-Y, P’Eng F-K and Chi C-W (1996) Paclitaxel-induced apoptosis in human gastric carcinoma cell lines. Cancer 77, 14-18.  http://dx.doi.org/10.1002/(SICI)1097-0142(19960101)77:1<14::AID-CNCR4>3.0.CO;2-N

Chee PP (1996) Plant regeneration from somatic embryos of Taxus brevifolia. Plant cell reports. 16, 184-187.

Collins-Pavao M, Chin CK and Pedersen H (1996) Taxol partitioning in two-phase plant cell cultures of Taxus brevifolia. Journal of Biotechnology 49, 95-100.  http://www.sciencedirect.com/science/article/pii/0168165696015258

Davelaar EM, Bonfrer JMG, Verstraeten RA, ten Bokkel Huinink WW and Kenemans P (1996) CA 125: A valid marker in ovarian carcinoma patients treated with paclitaxel? Cancer 78, 118-127.  http://dx.doi.org/10.1002/(SICI)1097-0142(19960701)78:1<118::AID-CNCR17>3.0.CO;2-2

DiFazio SP, Vance NC and Wilson MV (1996) Variation in sex expression of Taxus brevifolia in western Oregon. Canadian journal of botany = Journal canadien de botanique. 74, 1943-1946.

Donehower RC (1996) The Clinical Development of Paclitaxel: A Successful Collaboration of Academia, Industry and the National Cancer Institute. STEM CELLS 14, 25-28.  http://dx.doi.org/10.1002/stem.140025

Dordunoo SK and Burt HM (1996) Solubility and stability of taxol: effects of buffers and cyclodextrins. International Journal of Pharmaceutics 133, 191-201.  http://www.sciencedirect.com/science/article/pii/0378517396044432

Ellis DD, Zeldin EL, Brodhagen M, Russin WA and McCown BH (1996) Taxol production in nodule cultures of Taxus. Journal of natural products. 59, 246-250.

Ghersi D, Wilcken N, Simes J and Donoghue E (1996) Taxane containing regimens for metastatic breast cancer. In ‘Cochrane Database of Systematic Reviews’ (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/14651858.CD003366.pub2

Gocmen B, Jermstad KD, Neale DB and Kaya Z (1996) Development of random amplified polymorphic DNA markers for genetic mapping in Pacific yew (Taxus brevifolia). Canadian journal of forest research. 26, 497-503.

Guy R, Scott Z, Sloboda R and Nicolaou K (1996) Fluorescent taxoids. Chem Biol 3, 1021-31.

Guy RK, Scott ZA, Sloboda RD and Nicolaou KC (1996) Fluorescent taxoids. Chemistry &amp; Biology 3, 1021-1031.  http://www.sciencedirect.com/science/article/pii/S1074552196901684

Hefner J, Rubenstein SM, Ketchum REB, Gibson DM, Williams RM and Croteau R (1996) Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5a-o1: the first oxygenation step in taxol biosynthesis. Chemistry &amp; Biology 3, 479-489.  http://www.sciencedirect.com/science/article/pii/S1074552196900964

Huber MH, Lee JS, Newman RA, Fossella FV, Wester M, Hong WK and Lippman SM (1996) A phase I investigation of the sequential use of methotrexate and paclitaxel with and without G-CSF for the treatment of solid tumors. Ann. Onc. 7, 59-63.  http://annonc.oxfordjournals.org/cgi/content/abstract/7/1/59

Jaakkola M, Rantanen V, Grénman S, Kulmala J and Grénman R (1996) In vitro concurrent paclitaxel and radiation of four vulvar squamous cell carcinoma cell lines. Cancer 77, 1940-1946.  http://dx.doi.org/10.1002/(SICI)1097-0142(19960501)77:9<1940::AID-CNCR26>3.0.CO;2-Z

Kaufman D (1996) A Tribute to Bruce Chabner. STEM CELLS 14, 3-4.  http://dx.doi.org/10.1002/stem.140003

Kirsch-Volders M and Parry EM (1996) Genetic toxicology of mitotic spindle inhibitors used as anticancer drugs. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 355, 103-128.  http://www.sciencedirect.com/science/article/pii/0027510796000255

Lin X, Hezari M, Koepp AE, Floss HG and Croteau R (1996) Mechanism of taxadiene synthase, a diterpene cyclase that catalyzes the first step of taxol biosynthesis in Pacific yew. Biochemistry. 35, 2968-2977.

Luan EC, Allen SE and Bolyard MG (1996) Transient GUS expression in zygotic embryos of Taxus brevifolia. In vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association. 32, 81-85.

Ma Z, Tanzil D, Au BW and Wang N-HL (1996) Estimation of Solvent-Modulated Linear Adsorption Parameters of Taxanes from Dilute Plant Tissue Culture Broth. Biotechnology Progress 12, 810-821.  http://dx.doi.org/10.1021/bp9600748

Ma Z, Tanzil D, Au BW and Wang NHL (1996) Estimation of solvent-modulated linear adsorption parameters of taxanes from dilute plant tissue culture broth. Biotechnology progress. 12, 810-821.

Maldonado V, De Anda J and Meléndez-Zajgla J (1996) Paclitaxel-induced apoptosis in HeLa cells is serum dependent. Journal of Biochemical Toxicology 11, 183-188.  http://dx.doi.org/10.1002/(SICI)1522-7146(1996)11:4<183::AID-JBT3>3.0.CO;2-G

Manzano A, Roig T, Bermudez J and Bartrons R (1996) Effects of taxol on isolated rat hepatocyte metabolism. Am J Physiol Cell Physiol 271, C1957-1962.  http://ajpcell.physiology.org/cgi/content/abstract/271/6/C1957

Minore D, Weatherly HG and Cartmill M (1996) Seeds, seedlings, and growth of Pacific yew (Taxus brevifolia). Northwest science. 70, 223-229.

Mirjalili N and Linden JC (1996) Methyl Jasmonate Induced Production of Taxol in Suspension Cultures of Taxus cuspidata: Ethylene Interaction and Induction Models. Biotechnology Progress 12, 110-118.  http://dx.doi.org/10.1021/bp9500831

Moore D and Frazer LN (1996) One stop mycology. Mycological Research 100, 632-640.  http://www.sciencedirect.com/science/article/pii/S0953756296800207

Nemeth-Kiss V, Forgacs E, Cserhati T and Schmidt G (1996) Determination of taxol in Taxus species grown in Hungary by high-performance liquid chromatography-diode array detection. Effect of vegetative period. Journal of chromatography. A. 750, 253-256.

Németh-Kiss V, Forgács E, Cserháti T and Schmidt G (1996) Determination of taxol in Taxus species grown in Hungary by high-performance liquid chromatography-diode array detection effect of vegetative period. Journal of Chromatography A 750, 253-256.  http://www.sciencedirect.com/science/article/pii/0021967396005419

Nicolaou KC, Guy RK and Potier P (1996) Taxoids: new weapons against cancer. Scientific American. 274, 94-98.

Parekh H and Simpkins H (1996) Species-specific differences in taxol transport and cytotoxicity against human and rodent tumor cells: Evidence for an alternate transport system? Biochemical Pharmacology 51, 301-311.  http://www.sciencedirect.com/science/article/pii/0006295295021760

Pengsuparp T, Kingston DGI, Neidigh KA, Cordell GA and Pezzuto JM (1996) Evaluation of the cytotoxic mechanism mediated by baccatin III, the synthetic precursor of taxol. Chemico-Biological Interactions 101, 103-114.  http://www.sciencedirect.com/science/article/pii/0009279796037131

Pezzuto J (1996) Taxol production in plant cell culture comes of age. Nature biotechnology., 9.

Pienta KJ, Naik H and Lehr JE (1996) Effect of estramustine, etoposide, and taxol on prostate cancer cell growth in vitro and in vivo. Urology 48, 164-170.  http://www.sciencedirect.com/science/article/pii/S0090429596001094

Poon GK, Wade J, Bloomer J, Clarke SE and Maltas J (1996) Rapid Screening of Taxol Metabolites in Human Microsomes by Liquid Chromatography/ Electrospray Ionization-Mass Spectrometry. Rapid Communications in Mass Spectrometry 10, 1165-1168.  http://dx.doi.org/10.1002/(SICI)1097-0231(19960731)10:10<1165::AID-RCM608>3.0.CO;2-J

Pulici M, Sugawara F, Koshino H, Uzawa J and Yoshida S (1996) ChemInform Abstract: Metabolites of Endophytic Fungi of Taxus brevifolia: The First Highly Functionalized Humulane of Fungal Origin. ChemInform 27, no-no.  http://dx.doi.org/10.1002/chin.199652220

Pulici M, Sugawara F, Koshino H, Uzawa J, Yoshida S, Lobkovsky E and Clardy J (1996) ChemInform Abstract: Pestalotiopsins A and B: New Caryophyllenes from an Endophytic Fungus of Taxus brevifolia. ChemInform 27, no-no.  http://dx.doi.org/10.1002/chin.199631170

Pulici M, Sugawara F, Koshino H, Uzawa J, Yoshida S, Lobkovsky E and Clardy J (1996) A new isodrimeninol from Pestalotiopsis sp. Journal of natural products. 59, 47-48.

Rao KV, Bhakuni RS, Hanuman JB, Davies R and Johnson J (1996) Taxanes from the bark of Taxus brevifolia. Phytochemistry 41, 863-866.  http://www.sciencedirect.com/science/article/pii/0031942295006729

Raúl E C (1996) - Protein Model Building Using Structural Similarity. In ‘Advances in Computational Biology’ (Ed.^(Eds Hugo OV) pp. 65-119. (Elsevier Science B.V.: Amsterdam). http://www.sciencedirect.com/science/article/pii/B9781559389792500041

Redeker V, Rusconi F, Mary J, Promé D and Rossier J (1996) Structure of the C-Terminal Tail of α-Tubulin: Increase of Heterogeneity from Newborn to Adult. Journal of Neurochemistry 67, 2104-2114.  http://dx.doi.org/10.1046/j.1471-4159.1996.67052104.x

Rees CN, Sinnett D, Lowdell C, English J and Coombes RC (1996) A Pilot study to evaluate paclitaxel (Taxol™) as primary medical treatment for patients with inoperable stage III and IV breast carcinoma. European Journal of Cancer 32, 2354-2356.  http://www.sciencedirect.com/science/article/pii/S0959804996003486

Safran H, King T, et al. (1996) p53 mutations do not predict response to paclitaxel/radiation for nonsmall cell lung carcinoma. Cancer 78, 1203-1210.  http://dx.doi.org/10.1002/(SICI)1097-0142(19960915)78:6<1203::AID-CNCR6>3.0.CO;2-A

Seibel NL and Reaman GH (1996) New microtubular agents in pediatric oncology. Invest New Drugs 14, 49-54.

Sharma A, Sharma US and Straubinger RM (1996) Paclitaxel-liposomes for intracavitary therapy of intraperitoneal P388 leukemia. Cancer Letters 107, 265-272.  http://www.sciencedirect.com/science/article/pii/0304383596043807

Srinivasan V, Ciddi V, Bringi V and Shuler ML (1996) Metabolic Inhibitors, Elicitors, and Precursors as Tools for Probing Yield Limitation in Taxane Production by Taxuschinensis Cell Cultures. Biotechnology Progress 12, 457-465.  http://dx.doi.org/10.1021/bp9600344

Suzuki M, Saga Y, Sekiguchi I and Sato I (1996) Sensitization of human uterine cervical cancer cells to radiation using paclitaxel. Current Therapeutic Research 57, 430-437.  http://www.sciencedirect.com/science/article/pii/S0011393X96800518

Theodoridis G and Verpoorte R (1996) Taxol Analysis by High Performance Liquid Chromatography: A Review. Phytochemical Analysis 7, 169-184.  http://dx.doi.org/10.1002/(SICI)1099-1565(199607)7:4<169::AID-PCA305>3.0.CO;2-B

Van Pelt R and North MP (1996) Analyzing canopy structure in Pacific Northwest old-growth forests with a stand-scale crown model. Northwest science., 15-30.

Vandana V, Teja AS and Zalkow LH (1996) Supercritical extraction and HPLC analysis of taxol from Taxus brevifolia using nitrous oxide and nitrous oxide + ethanol mixtures. Fluid Phase Equilibria 116, 162-169.  http://www.sciencedirect.com/science/article/pii/0378381296029913

Wall ME and Wani MC (1996) Camptothecin and taxol: from discovery to clinic. Journal of Ethnopharmacology 51, 239-254.  http://www.sciencedirect.com/science/article/pii/0378874195013679

Walters-Vertucci C, Crane J and Vance NC (1996) Physiological aspects of Taxus brevifolia seeds in relation to seed storage characteristics. Physiologia Plantarum 98, 1-12.  http://dx.doi.org/10.1111/j.1399-3054.1996.tb00669.x

Wickremesinhe ERM and Arteca RN (1996) Effects of plant growth regulators applied to the roots of hydroponically grown Taxus × media plants on the production of taxol and related taxanes. Plant Science 121, 29-38.  http://www.sciencedirect.com/science/article/pii/S016894529604513X

Wildung MR and Croteau R (1996) A cDNA Clone for Taxadiene Synthase, the Diterpene Cyclase That Catalyzes the Committed Step of Taxol Biosynthesis. J. Biol. Chem. 271, 9201-9204.  http://www.jbc.org/cgi/content/abstract/271/16/9201

Yang S-P, Luh K-T and Yang P-C (1996) New developments in diagnosis and management of lung cancer. Respirology 1, 39-47.  http://dx.doi.org/10.1111/j.1440-1843.1996.tb00009.x

Yukimune Y, Tabata H, Higashi Y and Hara Y (1996) Methyl jasmonate-induced overproduction of paclitaxel and baccatin III in Taxus cell suspension cultures. Nature biotechnology., 9.

(1995) Teratology Society Abstracts. Teratology 51, 156-202.  http://dx.doi.org/10.1002/tera.1420510303

(1995) FDA approves taxol but not taxotere. HerbalGram. 34, 34.

Aapro M and Bruno R (1995) Early clinical studies with docetaxel. European Journal of Cancer 31, Supplement 4, S7-S10.  http://www.sciencedirect.com/science/article/pii/095980499500360U

Akutsu M, Kano Y, Tsunoda S, Suzuki K, Yazawa Y and Miura Y (1995) Schedule-dependent interaction between paclitaxel and doxorubicin in human cancer cell lines in vitro. European Journal of Cancer 31, 2341-2346.  http://www.sciencedirect.com/science/article/pii/0959804995004483

Arnal I and Wade RH (1995) How does taxol stabilize microtubules? Current Biology 5, 900-908.  http://www.sciencedirect.com/science/article/pii/S0960982295001801

Arslanian RL, Bailey DT, Kent MC, Richheimer SL, Thornburg KR, Timmons DW and Zheng QY (1995) Brevitaxin, a new diterpenolignan from the bark of Taxus brevifolia. J Nat Prod 58, 583-5.

Arslanian RL, Bailey DT, Kent MC, Richheimer SL, Thornburg KR, Timmons DW and Zheng QY (1995) ChemInform Abstract: Brevitaxin, a New Diterpenolignan from the Bark of Taxus brevifolia. ChemInform 26, no-no.  http://dx.doi.org/10.1002/chin.199542205

Arslanian RL, Bailey DT, Kent MC, Richhemer SL, Thornburg KR, Timmons DW and Zheng QY (1995) Brevitaxin, a new diterpenolignan from the bark of Taxus brevifolia. Journal of natural products. 58, 583-585.

Baguley BC, Marshall ES, et al. (1995) Resistance mechanisms determining the in vitro sensitivity to paclitaxel of tumour cells cultured from patients with ovarian cancer. European Journal of Cancer 31, 230-237.  http://www.sciencedirect.com/science/article/pii/095980499400472H

Banks RE, Jondi WJ, Pritchard RG and Tipping AE (1995) (E)-Acetophenone O-(3,4,5,6-Tetrafluoro-2-pyridyl)oxime, Formed by 2-Substitution of Pentafluoropyridine by (E)-Acetophenone Oximate. Acta Crystallographica Section C 51, 293-295.  http://dx.doi.org/10.1107/S0108270194009133

Bicker A, Levenback C, Burke TW, Morris M, Warner D, Dejesus Y and Gershenson DM (1995) Infusion site soft-tissue injury after paclitaxel administration. Cancer 76, 116-120.  http://dx.doi.org/10.1002/1097-0142(19950701)76:1<116::AID-CNCR2820760118>3.0.CO;2-P

Boros L, Garrow GC, Asbury RF and Chang AY (1995) Phase I study of escalating doses of paclitaxel (Taxol) with fixed doses of ifosfamide, carboplatin, and etoposide. Semin Oncol 22, 28-31.

Busing RT, Halpern CB and Spies TA (1995) Ecology of Pacific Yew (Taxus brevifolia) in Western Oregon and Washington. Conservation Biology 9, 1199-1207.  http://dx.doi.org/10.1046/j.1523-1739.1995.9051189.x-i1

Cannon PF and Hawksworth DL (1995) 14 The diversity of fungi associated with vascular plants: The known, the unknown and the need to bridge the knowledge gap. In ‘Advances in Plant Pathology’ (Ed.^(Eds Andrews JH and Tommerup IC) pp. 277-302. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0736453906800164

Cavaletti G, Bogliun G, Marzorati L, Zincone A, Marzola M, Colombo N and Tredici G (1995) Peripheral neurotoxicity of taxol in patients previously treated with cisplatin. Cancer 75, 1141-1150.  http://dx.doi.org/10.1002/1097-0142(19950301)75:5<1141::AID-CNCR2820750514>3.0.CO;2-U

Chee PP (1995) Organogenesis in Taxus brevifolia tissue cultures. Plant cell reports., 9.

Chee PP (1995) Stimulation of adventitious rooting of Taxus species by thiamine. Plant cell reports., 12.

Chiaroni A, Riche C, Marder R, Dubois J, Guénard D and Guéritte-Voegelein F (1995) A 10-Deacetylbaccatin III Derivative: 11,12-Dihydro-7-triethylsilyl-10-deacetylbaccatin III. Acta Crystallographica Section C 51, 2050-2053.  http://dx.doi.org/10.1107/S0108270195004616

David S E (1995) New drugs for treating small cell lung cancer. Lung Cancer 12, Supplement 3, S53-S61.  http://www.sciencedirect.com/science/article/pii/S0169500210800182

De Jong RJ and Bonnor GM (1995) Pilot inventory for Pacific yew. FRDA report. 231, 231.

Dohrn R and Brunner G (1995) High-pressure fluid-phase equilibria: Experimental methods and systems investigated (1988–1993). Fluid Phase Equilibria 106, 213-282.  http://www.sciencedirect.com/science/article/pii/037838129502703H

Elsohly HN, Croom EM, Kopycki WJ, Joshi AS, Elsohly MA and McChesney JD (1995) Concentrations of taxol and related taxanes in the needles of different Taxus cultivars. Phytochemical Analysis 6, 149-156.  http://dx.doi.org/10.1002/pca.2800060307

Ewald D, Weckwerth W, Naujoks G and Zocher R (1995) Formation of Embryo-like Structures in Tissue Cultures of Different Yew Species. Journal of Plant Physiology 147, 139-143.  http://www.sciencedirect.com/science/article/pii/S0176161711814264

Fett-Neto AG, Pennington JJ and DiCosmo F (1995) Effect of White Light on Taxol and Baccatin III Accumulation in Cell Cultures of Taxus cuspidata Sieb and Zucc. Journal of Plant Physiology 146, 584-590.  http://www.sciencedirect.com/science/article/pii/S0176161711819188

Francis PA, Kris MG, Rigas JR, Grant SC and Miller VA (1995) Paclitaxel (Taxol) and Docetaxel (Taxotere): active chemotherapeutic agents in lung cancer. Lung Cancer 12, Supplement 1, S163-S172.  http://www.sciencedirect.com/science/article/pii/016950029500432Z

Gao Q and Golik J (1995) 2’-Carbamate Taxol. Acta Crystallographica Section C 51, 295-298.  http://dx.doi.org/10.1107/S0108270194005317

Gatzemeier U, Heckmayr M, Neuhauss R, Schluter I, Pawel JV, Wagner H and Dreps A (1995) Phase II study with paclitaxel for the treatment of advanced inoperable non-small cell lung cancer. Lung Cancer 12 Suppl 2, S101-6.

Gatzemeier U, Heckmayr M, Neuhauss R, Schlüter I, Pawel JV, Wagner H and Dreps A (1995) Phase II study with paclitaxel for the treatment of advanced inoperable non-small cell lung cancer. Lung Cancer 12, Supplement 2, S101-S106.  http://www.sciencedirect.com/science/article/pii/S016950021080008X

Glantz MJ, Choy H, Kearns CM, Mills PC, Wahlberg LU, Zuhowski EG, Calabresi P and Egorin MJ (1995) Paclitaxel Disposition in Plasma and Central Nervous Systems of Humans and Rats With Brain Tumors. J Natl Cancer Inst 87, 1077-1081.  http://jnci.oxfordjournals.org/cgi/content/abstract/87/14/1077

Grothaus PG, Bignami GS, O’Malley S, Harada KE, Byrnes JB, Waller DF, Raybould TJ, McGuire MT and Alvarado B (1995) Taxane-specific monoclonal antibodies: measurement of taxol, baccatin III, and “total taxanes” in Taxus brevifolia extracts by enzyme immunoassay. J Nat Prod 58, 1003-14.

Grothaus PG, Bignami GS, O’Malley S, Harada KE, Byrnes JB, Waller DF, Raybould TJG, McGuire MT and Alvarado B (1995) Taxane-specific monoclonal antibodies: measurement of taxol, baccatin III, and “total taxanes” in Taxus brevifolia extracts by enzyme immunoassay. Journal of natural products. 58, 1003-1014.

Hezari M, Lewis NG and Croteau R (1995) Purification and Characterization of Taxa-4(5),11(12)-diene Synthase from Pacific Yew (Taxus Brevifolia) that Catalyzes the First Committed Step of Taxol Biosynthesis. Archives of Biochemistry and Biophysics 322, 437-444.  http://www.sciencedirect.com/science/article/pii/S0003986185714865

Huizing MT, Misser VH, Pieters RC, ten Bokkel Huinin WW, Veenhof CH, Vermorken JB, Pinedo HM and Beijnen JH (1995) Taxanes: a new class of antitumor agents. Cancer Invest 13, 381-404.

J.A A (1995) Therapy of carcinoma of the oesophagus: Either attempt it not or succeed. European Journal of Cancer 31, 790-793.  http://www.sciencedirect.com/science/article/pii/0959804994E0124M

Jagetia GC and Adiga SK (1995) Influence of various concentrations of taxol on cell survival, micronuclei induction, and LDH activity in cultured V79 cells. Cancer Letters 96, 195-200.  http://www.sciencedirect.com/science/article/pii/030438359503929Q

Kerns EH, Volk KJ, Hill SE and Lee MS (1995) Profiling new taxanes using LC/MS and LC/MS/MS substructural analysis techniques. Rapid Communications in Mass Spectrometry 9, 1539-1545.  http://dx.doi.org/10.1002/rcm.1290091514

Ketchum REB, Gibson DM and Gallo LG (1995) Media optimization for maximum biomass production in cell cultures of pacific yew. Plant cell, tissue and organ culture. 42, 185-193.

Kim JH, Yun JH, Hwang YS, Byun SY and Kim DI (1995) Production of taxol and related taxanes in Taxus brevifolia cell cultures: effect of sugar. Biotechnology letters. 17, 101-106.

Knick VC, Eberwein DJ and Miller CG (1995) Vinorelbine Tartrate and Paclitaxel Combinations: Enhanced Activity Against In Vivo P388 Murine Leukemia Cells. J Natl Cancer Inst 87, 1072-1077.  http://jnci.oxfordjournals.org/cgi/content/abstract/87/14/1072

Koepp AE, Hezari M, Zajicek J, Vogel BS, LaFever RE, Lewis NG and Croteau R (1995) Cyclization of Geranylgeranyl Diphosphate to Taxa-4 (5) ,11 (12) -diene Is the Committed Step of Taxol Biosynthesis in Pacific Yew. J. Biol. Chem. 270, 8686-8690.  http://www.jbc.org/cgi/content/abstract/270/15/8686

Kwak SS, Choi MS, Park YG, Yoo JS and Liu JR (1995) Taxol content in the seeds of Taxus spp. Phytochemistry. 40, 29-32.

Lavelle F, Combeau C and Commercon A (1995) [Taxoids: structural and experimental properties]. Bull Cancer 82, 249-64.

Lee JC, Yang X, Schwartz M, Strobel G and Clardy J (1995) The relationship between an endangered North American tree and an endophytic fungus. Chemistry &amp; Biology 2, 721-727.  http://www.sciencedirect.com/science/article/pii/1074552195901000

Lee SM, Betticher DC and Thatcher N (1995) Melanoma: chemotherapy. Br. Med. Bull. 51, 609-630.  http://bmb.oxfordjournals.org/cgi/content/abstract/51/3/609

M.-C B (1995) Preclinical pharmacology of docetaxel. European Journal of Cancer 31, Supplement 4, S1-S6.  http://www.sciencedirect.com/science/article/pii/095980499500357O

Mirjalili N and Linden JC (1995) Gas phase composition effects on suspension cultures of Taxus cuspidata. Biotechnology and Bioengineering 48, 123-132.  http://dx.doi.org/10.1002/bit.260480206

Nanduri VB, Hanson RL, LaPorte TL, Ko RY, Patel RN and Szarka LJ (1995) Fermentation and isolation of C10-deacetylase for the production of 10-deacetylbaccatin III from baccatin III. Biotechnology and Bioengineering 48, 547-550.  http://dx.doi.org/10.1002/bit.260480518

Nicolaou KC and Guy RK (1995) Die Eroberung von Taxol. Angewandte Chemie 107, 2247-2259.  http://dx.doi.org/10.1002/ange.19951071904

Nicolaou KC and Guy RK (1995) The Conquest of Taxol. Angewandte Chemie International Edition in English 34, 2079-2090.  http://dx.doi.org/10.1002/anie.199520791

Oberlies NH, Jones JL, Corbett TH, Fotopoulos SS and McLaughlin JL (1995) Tumor cell growth inhibition by several Annonaceous acetogenins in an in vitro disk diffusion assay. Cancer Letters 96, 55-62.  http://www.sciencedirect.com/science/article/pii/0304383595927597

Patel RN, Banerjee A, Howell JM, McNamee CG, Brzozowski D, Nanduri V, Thottathil JK and Szarka LJ (1995) Stereoselective Microbial Reduction of 2-Keto-3-(N-Benzoylamino)-3-Phenyl Propionic Acid Ethyl Ester. Annals of the New York Academy of Sciences 750, 166-174.  http://dx.doi.org/10.1111/j.1749-6632.1995.tb19946.x

Phillips KA, Fitzharris B, Friedlander M, McCrystal M, Olver I, Joughin J, Bishop J, Evans B and Smith J (1995) Australasian multicentre phase II study of paclitaxel (Taxol*) in relapsed ovarian cancer. Australian and New Zealand Journal of Medicine 25, 337-343.  http://dx.doi.org/10.1111/j.1445-5994.1995.tb01899.x

Postma TJ, Vermorken JB, Liefting AJM, Pinedo HM and Heimans JJ (1995) Paclitaxel-induced neuropathy. Ann. Onc. 6, 489-494.  http://annonc.oxfordjournals.org/cgi/content/abstract/6/5/489

Pronk LC, Stoter G and Verweij J (1995) Docetaxel (Taxotere): Single agent activity, development of combination treatment and reducing side-effects. Cancer Treatment Reviews 21, 463-478.  http://www.sciencedirect.com/science/article/pii/0305737295900306

Qazi F and McGuire WP (1995) The treatment of epithelial ovarian cancer. CA: A Cancer Journal for Clinicians 45, 88-101.  http://dx.doi.org/10.3322/canjclin.45.2.88

Rao KV, Bhakuni RS, Johnson J and Oruganti RS (1995) Synthesis and evaluation of some 10-mono- and 2’,10-diesters of 10-deacetylpaclitaxel. J Med Chem 38, 3411-4.

Rao KV, Hanuman JB, Alvarez C, Stoy M, Juchum J, Davies RM and Baxley R (1995) A new large-scale process for taxol and related taxanes from Taxus brevifolia. Pharm Res 12, 1003-10.

Reinhold U and Abken H (1995) Cutaneous T-cell lymphoma: Molecular genetics, immunology and pathogenesis. European Journal of Cancer 31, 793-799.  http://www.sciencedirect.com/science/article/pii/0959804995000892

Santibańez JF, Maccioni RB and Martínez J (1995) The secretion of urokinase-like plasminogen activator is inhibited by microtubule-interacting drugs. Cell Biochemistry and Function 13, 217-225.  http://dx.doi.org/10.1002/cbf.290130313

Schlosser WE, Blatner KA, Schuster EG and Carroll MS (1995) Potential for expansion of the special forest products industry in the Northern Rockies. Western journal of applied forestry. 10, 138-143.

Sharma A, Bernacki RJ, Straubinger RM and Ojima I (1995) Antitumor efficacy of taxane liposomes on a human ovarian tumor xenograft in nude athymic mice. Journal of Pharmaceutical Sciences 84, 1400-1404.  http://dx.doi.org/10.1002/jps.2600841204

Sharma US, Balasubramanian SV and Straubinger RM (1995) Pharmaceutical and physical properties of paclitaxel (taxol) complexes with cyclodextrins. Journal of Pharmaceutical Sciences 84, 1223-1230.  http://dx.doi.org/10.1002/jps.2600841015

Srinivasan V, Pestchanker L, Moser S, Hirasuna TJ, Taticek RA and Shuler ML (1995) Taxol production in bioreactors: Kinetics of biomass accumulation, nutrient uptake, and taxol production by cell suspensions of Taxus baccata. Biotechnology and Bioengineering 47, 666-676.  http://dx.doi.org/10.1002/bit.260470607

Steward WP and Dunlop DJ (1995) New drugs in the treatment of non-small cell lung cancer. Ann. Onc. 6, S49-54.  http://annonc.oxfordjournals.org/cgi/content/abstract/6/suppl_1/S49

Stierle A, Stierle D, Strobel G, Bignami G and Grothaus P (1995) Bioactive metabolites of the endophytic fungi of Pacific yew, Taxus brevifolia: paclitaxel, taxanes, and other bioactive compounds. ACS symposium series. 583, 583.

Stierle A, Strobel G, Stierle D, Grothaus P and Bignami G (1995) The search for a taxol-producing microorganism among the endophytic fungi of the Pacific yew, Taxus brevifolia. J Nat Prod 58, 1315-24.

Stromberg JS, Lee YJ, Armour EP, Martinez AA and Corry PM (1995) Lack of radiosensitization after paclitaxel treatment of three human carcinoma cell lines. Cancer 75, 2262-2268.  http://dx.doi.org/10.1002/1097-0142(19950501)75:9<2262::AID-CNCR2820750912>3.0.CO;2-5

Stull DP, Scales TA, Daughenbaugh R, Jans NA and Bailey DT (1995) Taxol (paclitaxel): strategies to increase the supply of a new anticancer drug. Applied biochemistry and biotechnology. 54, 133-140.

Tamura T, Sasaki Y, Nishiwaki Y and Saijo N (1995) Phase I Study of Paclitaxel by Three-hour Infusion: Hypotension Just after Infusion Is One of the Major Dose-limiting Toxicities. Cancer Science 86, 1203-1209.  http://dx.doi.org/10.1111/j.1349-7006.1995.tb03316.x

Voravud N, Sriuranpong V and Foofung S (1995) 1111 A phase II study of paclitaxel in patients with non-small cell lung cancer. European Journal of Cancer 31, Supplement 6, S231.  http://www.sciencedirect.com/science/article/pii/095980499596357J

Wall ME and Wani MC (1995) Camptothecin and Taxol: Discovery to Clinic—Thirteenth Bruce F. Cain Memorial Award Lecture. Cancer Res. 55, 753-760.  http://cancerres.aacrjournals.org/cgi/content/abstract/55/4/753

Wendler S, Kronberg I, Breitenbach J and Fisch J (1995) Wissenschaft. Biologie in unserer Zeit 25, 283-287.  http://dx.doi.org/10.1002/biuz.19950250505

Wheeler NC, Jech KS, Masters SA, O’Brien CJ, Timmons DW, Stonecypher RW and Lupkes A (1995) Genetic variation and parameter estimates in Taxus brevifolia (Pacific yew). Canadian journal of forest research. 25, 1913-1927.

(1994) Paclitaxel in the treatment of lung cancer : David S. Ettinger, M.D. The Johns Hopkins Oncology Center, Baltimore, MD 21287. Lung Cancer 11, Supplement 2, 76-77.  http://www.sciencedirect.com/science/article/pii/0169500294920583

(1994) Notizen. Nachrichten aus Chemie, Technik und Laboratorium 42, 350-352.  http://dx.doi.org/10.1002/nadc.19940420404

(1994) Consilium Cedip Praktikum — Handbuch für Diagnose und Therapie. Elektronisches Buch in Anbindung an med. InfoLINK Vers. 2.0. 21. deutsche Aufl., Cedip Medizinisch technische Verlags- und Handelsgesellschaft mbH, 85737 Ismaning 1992, DM 148,—. J. E. Altwein et al. ISBN 3-9802011-3-9. Pharmazie in unserer Zeit 23, 129-129.  http://dx.doi.org/10.1002/pauz.19940230222

Ajani JA, Dodd LG, Daugherty K, Warkentin D and Ilson DH (1994) Taxol-Induced Soft-Tissue Injury Secondary to Extravasation: Characterization by Histopathology and Clinical Course. J Natl Cancer Inst 86, 51-53.  http://jnci.oxfordjournals.org

Ajani JA, Ilson DH, Daugherty K, Pazdur R, Lynch PM and Kelsen DP (1994) Activity of Taxol in Patients With Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus. J Natl Cancer Inst 86, 1086-1091.  http://jnci.oxfordjournals.org/cgi/content/abstract/86/14/1086

Arbuck SG, Dorr A and Friedman MA (1994) Paclitaxel (Taxol) in breast cancer. Hematol Oncol Clin North Am 8, 121-40.

Balasubramanian SV, Alderfer JL and Straubinger RM (1994) Solvent- and concentration-dependent molecular interactions of taxol (paclitaxel). Journal of Pharmaceutical Sciences 83, 1470-1476.  http://dx.doi.org/10.1002/jps.2600831021

Barker G (1994) Author’s reply. BJOG: An International Journal of Obstetrics & Gynaecology 101, 830-830.  http://dx.doi.org/10.1111/j.1471-0528.1994.tb11964.x

Boven E, Venema-Gaberscek E, Erkelens CAM, Bissery MC and Pinedo HM (1994) Abstracts

Antitumor activity of taxotere (RP 56976, NSC 628503), a new taxol analog, in experimental ovarian cancer. Ann. Onc. 5, 63-205.  http://annonc.oxfordjournals.org http://annonc.oxfordjournals.org/cgi/content/abstract/4/4/321

Brahn E, Tang C and Banquerigo ML (1994) Regression of collagen-induced arthritis with taxol, a microtubule stabilizer. Arthritis & Rheumatism 37, 839-845.  http://dx.doi.org/10.1002/art.1780370611

Breslow N, Olshan A, Beckwith JB, Moksness J, Feigl P and Green D (1994) Ethnic Variation in the Incidence, Diagnosis, Prognosis, and Follow-up of Children With Wilms’ Tumor. J Natl Cancer Inst 86, 49-51.  http://jnci.oxfordjournals.org

Chee PP (1994) In vitro culture of xygotic embryos of Taxus species. HortScience : a publication of the American Society for Horticultural Science. 29, 695-697.

Chen R and Kingston DG (1994) Isolation and structure elucidation of new taxoids from Taxus brevifolia. J Nat Prod 57, 1017-21.

Chen R and Kingston DGI (1994) Isolation and structure elucidation of new taxoids from Taxus brevifolia. Journal of natural products. 57, 1017-1021.

Chordia MD, Chaudhary AG, Kingston DGI, Jiang YQ and Hamel E (1994) Synthesis and biological evaluation of 4-deacetoxypaclitaxel. Tetrahedron letters : the international organ for the rapid publication of preliminary communications in organic chemistry. 35, 6843-6846.

Chu A, Furlan M, Davin LB, Zajicek J, Neil Towers GH, Soucy-Breau CM, Rettig SJ, Croteau R and Lewis NG (1994) Phenylbutanoid and taxane-like metabolites from needles of Taxus brevifolia. Phytochemistry 36, 975-985.  http://www.sciencedirect.com/science/article/pii/S0031942200904758

Chu A, Furlan M, Davin LB, Zajicek J, Towers GHN, Soucy-Breau CM, Rettig SJ, Croteau R and Lewis NG (1994) Phenylbutanoid and taxane-like metabolites from needles of Taxus brevifolia. Phytochemistry. 36, 975-985.

David G.I K (1994) Taxol: The chemistry and structure-activity relationships of a novel anticancer agent. Trends in Biotechnology 12, 222-227.  http://www.sciencedirect.com/science/article/pii/0167779994901201

Dimopoulos MA, Arbuck S, Huber M, Weber D, Luckett R, Delasalle K and Alexanian R (1994) Subject Index

Primary therapy of multiple myeloma with paclitaxel (Taxol). J. Hered. 85, 500-503.  http://jhered.oxfordjournals.org http://annonc.oxfordjournals.org/cgi/content/abstract/5/8/757

Durzan DJ and Ventimiglia F (1994) Free taxanes and the release of bound compounds having taxane antibody reactivity by xylanase in female, haploid-derived cell suspension cultures of Taxus brevifolia. In vitro cellular & developmental biology. Plant : journal of the Tissue Culture Association. 30P, 219-227.

El-Kassaby YA and Yanchuk AD (1994) Genetic Diversity, Differentiation, and Inbreeding in Pacific Yew from British Columbia. J. Hered. 85, 112-117.  http://jhered.oxfordjournals.org/cgi/content/abstract/85/2/112

Elsohly HN, Croom EM, El-Kashoury E, Elsohly MA and McChesney JD (1994) Taxol content of stored fresh and dried Taxus clippings. Journal of natural products. 57, 1025-1028.

Fett-Neto AG, Melanson SJ, Nicholson SA, Pennington JJ and DiCosmo F (1994) Improved taxol yield by aromatic carboxylic acid and amino acid feeding to cell cultures of taxus cuspidata. Biotechnology and Bioengineering 44, 967-971.  http://dx.doi.org/10.1002/bit.260440813

Fett-Neto AG, Zhang WY and Dicosmo F (1994) Kinetics of taxol production, growth, and nutrient uptake in cell suspensions of Taxus cuspidata. Biotechnology and Bioengineering 44, 205-210.  http://dx.doi.org/10.1002/bit.260440209

Fjällskog ML, Frii L and Bergh J (1994) Paclitaxel-induced cytotoxicity—the effects of cremophor EL (castor oil) on two human breast cancer cell lines with acquired multidrug resistant phenotype and induced expression of the permeability glycoprotein. European Journal of Cancer 30, 687-690.  http://www.sciencedirect.com/science/article/pii/0959804994905460

Foa R, Norton L and Seidman AD (1994) Taxol (paclitaxel): a novel anti-microtubule agent with remarkable anti-neoplastic activity. Int J Clin Lab Res 24, 6-14.

Geard CR and Jones JM (1994) Radiation and taxol effects on synchronized human cervical carcinoma cells. International Journal of Radiation Oncology*Biology*Physics 29, 565-569.  http://www.sciencedirect.com/science/article/pii/036030169490457X

Georg GI, Ali SM, Boge TC, Datta A, Falborg L and Himes RH (1994) Selective C-2 and C-4 deacylation and acylation of taxol: The first synthesis of a C-4 substituted taxol analogue. Tetrahedron Letters 35, 8931-8934.  http://www.sciencedirect.com/science/article/pii/0040403994883920

Georg GI, Boge TC, Cheruvallath ZS, Harriman GCB, Hepperle M, Park H and Himes RH (1994) Schotten-Baumann acylation of N-debenzoyltaxol; an efficient route to N-acyl taxol analogues and their biological evaluation. Bioorganic &amp; Medicinal Chemistry Letters 4, 335-338.  http://www.sciencedirect.com/science/article/pii/S0960894X01801396

Gimon ME, Kinsel GR, Edmondson RD, Russell DH, Prout TR and Ewald HA (1994) Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of paclitaxel and related taxanes. J Nat Prod 57, 1404-10.

Gimon ME, Kinsel GR, Edmondson RD, Russell DH, Prout TR and Ewald HA (1994) Matrix-assisted laser desorption ionization time-of-flight mass spectrometry of paclitaxel and related taxanes. Journal of natural products. 57, 1404-1410.

Gomez Paloma L, Guy RK, Wrasidlo W and Nicolaou KC (1994) Conformation of a water-soluble derivative of taxol in water by 2D-NMR spectroscopy. Chemistry &amp; Biology 1, 107-112.  http://www.sciencedirect.com/science/article/pii/1074552194900485

Gotaskie GE and Andreassi BF (1994) Paclitaxel: a new antimitotic chemotherapeutic agent. Cancer Pract 2, 27-33.

Graf E (1994) Drogen und ihre Inhaltsstoff, Pharmazeutische Biologie Band 2, 5. neubearb. Aufl. 1993. Von H. Wagner, G. Fischer Verl., Stuttgart, XII, 522 S., 330 Abb. und Formelbilder, geb. DM 86,—. Pharmazie in unserer Zeit 23, 129-129.  http://dx.doi.org/10.1002/pauz.19940230219

Graf E (1994) Heilpflanzen. Kleine Teekunde für den Hausgebrauch: Alltagsbeschwerden selbst behandeln. Von Lj. Kraus und J. Carstens. Verlag Trias — Thieme-Hippokrates-Enke Stuttgart 1993, 138 S. 6 farb. Abb., 6 Tab., brosch., DM 24,80. Pharmazie in unserer Zeit 23, 129-129.  http://dx.doi.org/10.1002/pauz.19940230221

Graf E (1994) Lexikon der Biochemie und Molekularbiologie. Ergänzungsband 1993 A—Z, Red. von S. Ganter und R. Sauermost. Herder Verl. Freiburg/Basel/Wien 1993, 224 S., DM 168.—. Pharmazie in unserer Zeit 23, 129-129.  http://dx.doi.org/10.1002/pauz.19940230220

Guchelaar HJ, ten Napel CH, de Vries EG and Mulder NH (1994) Clinical, toxicological and pharmaceutical aspects of the antineoplastic drug taxol: a review. Clin Oncol (R Coll Radiol) 6, 40-8.

Guchelaar HJ, Ten Napel CHH, de Vries EGE and Mulder NH (1994) Clinical, toxicological and pharmaceutical aspects of the antineoplastic drug taxol: A review. Clinical Oncology 6, 40-48.  http://www.sciencedirect.com/science/article/pii/S093665550580367X

Guo Y, Jaziri M, Diallo B, Vanhaelen-Fastre R, Zhiri A, Vanhaelen M, Homes J and Bombardelli E (1994) Immunological detection and quantitation of 10-deacetylbaccatin III in Taxus sp. plant and tissue cultures. Biological chemistry Hoppe-Seyler. 375, 281-287.

Han K-H, Fleming P, Walker K, Loper M, Scott Chilton W, Mocek U, Gordon MP and Floss HG (1994) Genetic transformation of mature Taxus: an approach to genetically control the in vitro production of the anticancer drug, taxol. Plant Science 95, 187-196.  http://www.sciencedirect.com/science/article/pii/0168945294900922

Heide L (1994) Pharmazeutische Biologie im Blickpunkt. Pharmazie in unserer Zeit 23, 100-104.  http://dx.doi.org/10.1002/pauz.19940230209

Heinstein PF and Chang CJ (1994) Taxol. Annual review of plant physiology and plant molecular biology., 45.