Australian New Crops Info 2016
Supported by the Rural Industries Research and Development Corporation

Listing of Interesting Plants of the World:

Podophyllum peltatum

 

 

This species is usually known as:

Podophyllum peltatum

 

This species has also been known as:

Podophyllum peltatum f. peltatum

 

Common names:

Mayapple, May Apple, Hogapple, Indian Apple, Mayflower, Umbrella Plant, Wild Lemon, Wild Mandrake, American Mandrake

 

 

Trends (five databases) 1901-2013:
[Number of papers mentioning Podophyllum peltatum: 896]

 

Podophyllum peltatum.jpg

 

Popularity of Podophyllum peltatum over time
[Left-hand Plot: Plot of numbers of papers mentioning Podophyllum peltatum (histogram and left hand axis scale of left-hand plot) and line of best fit, 1901 to 2013 (equation and % variation accounted for in box); Right-hand Plot: Plot of a proportional micro index, derived from numbers of papers mentioning Podophyllum peltatum as a proportion (scaled by multiplying by one million) of the approximate total number of papers available in databases for that year (frequency polygon and left-hand axis scale of right-hand plot) and line of best fit, 1901 to 2013 (equation and % variation accounted for in box)] 

[For larger charts showing the numbers of papers that have mentioned this species over years, select this link; there are links to come back from there]

 

Keywords

[Total number of keywords included in the papers that mentioned this species: 3141]

 

Podophyllotoxin (71), Podophyllum peltatum (37), lignans (34), Etoposide (18), Cancer (17), Cytotoxicity (16), natural products (16), biosynthesis (13), Podophyllum (13), Medicinal plants (12), Teniposide (11), Coevolution (10), Drug discovery (9), local adaptation (9), Anticancer activity (8), apoptosis (8), Berberidaceae (8), secondary metabolites (8), Tubulin (8), Clonal plant (7), Competition (7), Ethnobotany (7), rhizomes (7), Anticancer (6), aryltetralin (6), Chemotaxonomy (6), conservation (6), evolution (6), Herbs (6), lignan (6), Podophyllotoxin derivatives (6), Podophyllum hexandrum (6), Taxol (6), Traditional medicine (6), anticancer drugs (5), antineoplastic agents (5), clonal growth (5), cost of reproduction (5), curcumin (5), dispersal (5), drugs (5), endophytes (5), Endophytic fungus (5), frequency-dependent selection (5), Internet resource (5), leaves (5), Linaceae (5), Neolignans (5), Nutrition (5), Phenology (5), phenotypic plasticity (5), phylogeny (5), Succession (5), virulence (5), Acer saccharum (4), angiogenesis (4), anticancer agents (4), Biosynthetic pathway (4), Camptothecin (4), cell cycle (4), chemical constituents of plants (4), Disturbance (4), Diversity (4), Essential oils (4), fruit set (4), genetic diversity (4), herbal medicines (4), Menispermaceae (4), nutraceuticals (4), palladium (4), phytotoxins (4), plant biochemistry (4), plant breeding (4), plant extracts (4), plant genetics (4), plant physiology (4), plants (4), Podophyllum peltatum L. (4), Radio frequency heating (4), roots (4), Tolerance (4), β-Peltatin (4), 6-Methoxypodophyllotoxin (3), Agriculture (3), alkaloids (3), alkylating (3), Alliaria petiolata (3), antimuscarinic (3), Antiproliferative activity (3), Arbuscular mycorrhizal fungi (3), Aristolochia (3), Aryltetralin lignan (3), Aryltetralin lignans (3), Attractiveness (3), Betulaceae (3), bioavailability (3), Biomass production (3), Botanicals (3), Burseraceae (3), calcium oxalate (3), Cancer therapy (3), cardiotoxic (3), Carpinus betalus (3), Chemoprevention (3).....

 

[If all keywords are not here (as indicated by .....), they can be accessed from this link; there are links to come back from there]

 

 

Most likely scope for crop use/product (%):
[Please note: When there are only a few papers mentioning a species, care should be taken with the interpretation of these crop use/product results; as well, a mention may relate to the use of a species, or the context in which it grows, rather than a product]

 

poison (58.00), resin (11.46), hemiparasite (6.37), medicinal (4.60), weed (2.65), timber (1.55), ornamental (1.39), fruit (1.30), cereal (1.08), grain legume (1.01).....

 

[To see the full list of crop use/product outcomes, from searching abstracts of the papers that have mentioned this species, select this link; details of the analysis process have also been included; there are links to come back from there]

 

 

Recent mentions of this species in the literature:
[since 2012, with links to abstracts; The references from 1901-2013 which have been used for the trend, keyword and crop use/product analyses below, are listed below these references]

 

Droege H, Geißler J, Grimm A, Korenika V, Lorz T, Pfaller C, Schmitz M and Wurster J (2017) 34 - Materia medica (Arzneimittelbilder). In ‘Leitfaden Homöopathie (3. Auflage)’ (Ed.^(Eds  pp. 979-1172. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B9783437563539000347

Huang J, Xu M, Li S, He J and Xu H (2017) Synthesis of some ester derivatives of 4′-demethoxyepipodophyllotoxin/2′-chloro-4′-demethoxyepipodophyllotoxin as insecticidal agents against oriental armyworm, Mythimna separata Walker. Bioorganic & Medicinal Chemistry Letters 27, 511-517. //www.sciencedirect.com/science/article/pii/S0960894X16312938

Leonti M, Stafford GI, Cero MD, Cabras S, Castellanos ME, Casu L and Weckerle CS (2017) Reverse ethnopharmacology and drug discovery. Journal of Ethnopharmacology 198, 417-431. //www.sciencedirect.com/science/article/pii/S0378874116317846

Mathibe LJ, Botha J and Naidoo S (2017) Effects of Z-venusol, isolated from Gunnera perpensa L., on IL-6 and cAMP activity in human breast cancer cells in vitro. South African Journal of Botany 108, 96-99. //www.sciencedirect.com/science/article/pii/S0254629916303891

Naman CB, Benatrehina PA and Kinghorn AD (2017) Pharmaceuticals, Plant Drugs A2 - Thomas, Brian. In ‘Encyclopedia of Applied Plant Sciences (Second Edition)’ (Ed.^(Eds Murray BG and Murphy DJ) pp. 93-99. (Academic Press: Oxford). //www.sciencedirect.com/science/article/pii/B9780123948076001635

Nguyen VT, Sakoff JA and Scarlett CJ (2017) Physicochemical properties, antioxidant and anti-proliferative capacities of dried leaf and its extract from Xao tam phan (Paramignya trimera). Chemistry & Biodiversity, n/a-n/a. http://dx.doi.org/10.1002/cbdv.201600498

Rehman M, Hansen JL, Mallory-Smith CA and Zemetra RS (2017) Impact of transgene genome location on gene migration from herbicide-resistant wheat (Triticum aestivum L.) to jointed goatgrass (Aegilops cylindrica Host). Pest Management Science, n/a-n/a. http://dx.doi.org/10.1002/ps.4490

Wang Z-Z, Sun W-X, et al. (2017) Design, Synthesis, Biological evaluation and 3D−QSAR Analysis of podophyllotoxin dioxazole combination as tubulin targeting anticancer agents. Chemical Biology & Drug Design, n/a-n/a. http://dx.doi.org/10.1111/cbdd.12942

Yu X, Che Z and Xu H (2017) Recent Advances in the Chemistry and Biology of Podophyllotoxins. Chemistry – A European Journal, n/a-n/a. http://dx.doi.org/10.1002/chem.201602472

Zhao L, Shao Z and Shanks JV (2017) Anticancer Drugs. In ‘Industrial Biotechnology’ (Ed.^(Eds  pp. 237-269. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527807833.ch8

(2016) Podophyllum derivatives A2 - Aronson, J.K. In ‘Meyler’s Side Effects of Drugs (Sixteenth Edition)’ (Ed.^(Eds  pp. 844-845. (Elsevier: Oxford). //www.sciencedirect.com/science/article/pii/B9780444537171013093

(2016) Table of Contents. Disease-a-Month 62, 39. //www.sciencedirect.com/science/article/pii/S0011502916000286

(2016) 14 - Phytopharmaka bei Tumorerkrankungen A2 - Schilcher, Heinz. In ‘Leitfaden Phytotherapie (5. Auflage)’ (Ed.^(Eds  pp. 1017-1034. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B9783437553448000144

(2016) 2 - Pflanzenprofile A2 - Schilcher, Heinz. In ‘Leitfaden Phytotherapie (5. Auflage)’ (Ed.^(Eds  pp. 37-380. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B9783437553448000028

Ali-Seyed M, Jantan I, Vijayaraghavan K and Bukhari SNA (2016) Betulinic Acid: Recent Advances in Chemical Modifications, Effective Delivery, and Molecular Mechanisms of a Promising Anticancer Therapy. Chemical Biology & Drug Design 87, 517-536. http://dx.doi.org/10.1111/cbdd.12682

Anadón A, Martínez-Larrañaga MR, Ares I and Martínez MA (2016) Chapter 60 - Interactions between Nutraceuticals/Nutrients and Therapeutic Drugs A2 - Gupta, Ramesh C. In ‘Nutraceuticals’ (Ed.^(Eds  pp. 855-874. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128021477000607

Clere N (2016) Prise en charge de la diarrhée et de la constipation à l’officine. Actualités Pharmaceutiques 55, 48-51. //www.sciencedirect.com/science/article/pii/S051537001630297X

Diederich M and Cerella C (2016) Non-canonical programmed cell death mechanisms triggered by natural compounds. Seminars in Cancer Biology 40–41, 4-34. //www.sciencedirect.com/science/article/pii/S1044579X16300219

Efferth T, Banerjee M, et al. (2016) Biopiracy of natural products and good bioprospecting practice. Phytomedicine 23, 166-173. //www.sciencedirect.com/science/article/pii/S0944711315003797

Firempong CK, Zhang HY, et al. (2016) Segetoside I, a plant-derived bisdesmosidic saponin, induces apoptosis in human hepatoma cells in vitro and inhibits tumor growth in vivo. Pharmacological Research 110, 101-110. //www.sciencedirect.com/science/article/pii/S1043661816304030

Galland-Decker C, Charmoy A, Jolliet P, Spertini O, Hugli O and Pantet O (2016) Progressive Organ Failure After Ingestion of Wild Garlic Juice. The Journal of Emergency Medicine 50, 55-60. //www.sciencedirect.com/science/article/pii/S0736467915006435

Gerlero P and Hernández-Martín Á (2016) Actualización sobre el tratamiento de las verrugas vulgares en los niños. Actas Dermo-Sifiliográficas 107, 551-558. //www.sciencedirect.com/science/article/pii/S0001731016300813

Gerlero P and Hernández-Martín Á (2016) Treatment of Warts in Children: An Update. Actas Dermo-Sifiliográficas (English Edition) 107, 551-558. //www.sciencedirect.com/science/article/pii/S1578219016301329

Gurung AB, Bhattacharjee A and Ali MA (2016) Exploring the physicochemical profile and the binding patterns of selected novel anticancer Himalayan plant derived active compounds with macromolecular targets. Informatics in Medicine Unlocked 5, 1-14. //www.sciencedirect.com/science/article/pii/S2352914816300235

Hossen MJ, Kim M-Y, Kim J-H and Cho JY (2016) Codonopsis lanceolata: A Review of Its Therapeutic Potentials. Phytotherapy Research 30, 347-356. http://dx.doi.org/10.1002/ptr.5553

Jacobo-Herrera NJ, Jacobo-Herrera FE, Zentella-Dehesa A, Andrade-Cetto A, Heinrich M and Pérez-Plasencia C (2016) Medicinal plants used in Mexican traditional medicine for the treatment of colorectal cancer. Journal of Ethnopharmacology 179, 391-402. //www.sciencedirect.com/science/article/pii/S0378874115302968

Jafri L, Saleem S, Kondrytuk TP, Haq I-u, Ullah N, Pezzuto JM and Mirza B (2016) Hedera nepalensis K. Koch: A Novel Source of Natural Cancer Chemopreventive and Anticancerous Compounds. Phytotherapy Research 30, 447-453. http://dx.doi.org/10.1002/ptr.5546

Kandil S, Wymant JM, Kariuki BM, Jones AT, McGuigan C and Westwell AD (2016) Novel cis-selective and non-epimerisable C3 hydroxy azapodophyllotoxins targeting microtubules in cancer cells. European Journal of Medicinal Chemistry 110, 311-325. //www.sciencedirect.com/science/article/pii/S0223523415304232

Kolarević S, Gačić Z, Kostić J, Sunjog K, Kračun-Kolarević M, Paunović M, Knežević-Vukčević J and Vuković-Gačić B (2016) Impact of Common Cytostatics on DNA Damage in Freshwater Mussels Uniopictorum and Unio tumidus. CLEAN – Soil, Air, Water 44, 1471-1476. http://dx.doi.org/10.1002/clen.201500482

Kuo Y-C and Chao I-W (2016) Conjugation of melanotransferrin antibody on solid lipid nanoparticles for mediating brain cancer malignancy. Biotechnology Progress 32, 480-490. http://dx.doi.org/10.1002/btpr.2214

Lee H-E, Nam J-S, Shin J-A, Hong I-S, Yang I-H, You M-J and Cho S-D (2016) Convallaria keiskei as a novel therapeutic alternative for salivary gland cancer treatment by targeting myeloid cell leukemia-1. Head & Neck 38, E761-E770. http://dx.doi.org/10.1002/hed.24096

Lim CS, Chhabra N, Leikin S, Fischbein C, Mueller GM and Nelson ME (2016) Atlas of select poisonous plants and mushrooms. Disease-a-Month 62, 41-66. //www.sciencedirect.com/science/article/pii/S0011502915001972

Lohiya NK, Balasubramanian K and Ansari AS (2016) Indian folklore medicine in managing men’s health and wellness. Andrologia 48, 894-907. http://dx.doi.org/10.1111/and.12680

Maatouk I, Helou J, Abdo K and Fouere S (2016) Risque de transmission des HPV par la solution de podophylline. Annales de Dermatologie et de Vénéréologie 143, S322-S323. //www.sciencedirect.com/science/article/pii/S0151963816308997

Maier W, McTaggart AR, Roux J and Wingfield MJ (2016) Phakopsora myrtacearum sp. nov., a newly described rust (Pucciniales) on eucalypts in eastern and southern Africa. Plant Pathology 65, 189-195. http://dx.doi.org/10.1111/ppa.12406

Manget L (2016) Natures Emporium: The Botanical Drug Trade and the Commons Tradition in Southern Appalachia, 1847-1917. Environmental History 21, 660-687. http://envhis.oxfordjournals.org/cgi/content/abstract/21/4/660

Mao Y, Zhang Y, Xu C and Qiu Y (2016) Comparative transcriptome resources of two Dysosma species (Berberidaceae) and molecular evolution of the CYP719A gene in Podophylloideae. Molecular Ecology Resources 16, 228-241. http://dx.doi.org/10.1111/1755-0998.12415

Matamoro-Vidal A, Prieu C, Furness CA, Albert B and Gouyon P-H (2016) Evolutionary stasis in pollen morphogenesis due to natural selection. New Phytologist 209, 376-394. http://dx.doi.org/10.1111/nph.13578

Muñoz Cendales DR and Cuca Suárez LE (2016) Compuestos citotóxicos de origen vegetal y su relación con proteínas inhibidoras de apoptosis (IAP). Revista Colombiana de Cancerología 20, 124-134. //www.sciencedirect.com/science/article/pii/S0123901516300038

Nadumane VK, Venkatachalam P and Gajaraj B (2016) Chapter 19 - Aspergillus Applications in Cancer Research A2 - Gupta, Vijai Kumar. In ‘New and Future Developments in Microbial Biotechnology and Bioengineering’ (Ed.^(Eds  pp. 243-255. (Elsevier: Amsterdam). //www.sciencedirect.com/science/article/pii/B9780444635051000208

Patel H, Joshi A, Joshi A and Stagni G (2016) Transdermal Delivery of Etoposide Phosphate I: In Vitro and In Vivo Evaluation. Journal of Pharmaceutical Sciences 105, 2114-2122. //www.sciencedirect.com/science/article/pii/S0022354916413870

Paul D, Chanukuppa V, Reddy PJ, Taunk K, Adhav R, Srivastava S, Santra MK and Rapole S (2016) Global proteomic profiling identifies etoposide chemoresistance markers in non-small cell lung carcinoma. Journal of Proteomics 138, 95-105. //www.sciencedirect.com/science/article/pii/S1874391916300306

Pizzorno JE, Murray MT and Joiner-Bey H (2016) 77 - Uterine fibroids. In ‘The Clinician’s Handbook of Natural Medicine (THIRD EDITION)’ (Ed.^(Eds  pp. 936-944. (Churchill Livingstone: Edinburgh). //www.sciencedirect.com/science/article/pii/B9780702055140000865

Prasad S, Gupta SC and Aggarwal BB (2016) Serendipity in Cancer Drug Discovery: Rational or Coincidence? Trends in Pharmacological Sciences 37, 435-450. //www.sciencedirect.com/science/article/pii/S0165614716000584

Rocha JC, Busatto FF, Guecheva TN and Saffi J (2016) Role of nucleotide excision repair proteins in response to DNA damage induced by topoisomerase II inhibitors. Mutation Research/Reviews in Mutation Research 768, 68-77. //www.sciencedirect.com/science/article/pii/S138357421630028X

Taleb RI, Najm P, Shebaby W, Boulos JC, Demirdjian S, Hariri E, El-Sibai M, Daher C and Mroueh M (2016) β-2-himachalen-6-ol: A novel anticancer sesquiterpene unique to the Lebanese wild carrot. Journal of Ethnopharmacology 190, 59-67. //www.sciencedirect.com/science/article/pii/S0378874116303336

Tang Z-B, Chen Y-Z, Zhao J, Guan X-W, Bo Y-X, Chen S-W and Hui L (2016) Conjugates of podophyllotoxin and norcantharidin as dual inhibitors of topoisomerase and protein phosphatase 2A. European Journal of Medicinal Chemistry 123, 568-576. //www.sciencedirect.com/science/article/pii/S0223523416305797

Theobald Jr RJ (2016) Podophyllotoxin. In ‘Reference Module in Biomedical Sciences’ (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780128012383928447

Traidl-Hoffmann C (2016) Phytotherapie in der Dermatologie – natürlich gut?! JDDG: Journal der Deutschen Dermatologischen Gesellschaft 14, 867-869. http://dx.doi.org/10.1111/ddg.13123

Vorobiev E and Lebovka N (2016) 2 - Extraction From Foods and Biomaterials Enhanced by Pulsed Electric Energy. In ‘Innovative Food Processing Technologies’ (Ed.^(Eds  pp. 31-56. (Woodhead Publishing). //www.sciencedirect.com/science/article/pii/B978008100294000002X

Wei Z, Zhang J, Wang Y and Fan J (2016) Formulation development and systematic characterization of etoposide encapsulated solid lipid nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine 12, 508. //www.sciencedirect.com/science/article/pii/S1549963415004001

Xiong Y-Z, Xie M and Huang S-Q (2016) Influence of plant size on female-biased sex allocation in a single-flowered, nectarless herb. AoB Plants 8, plv139-. http://aobpla.oxfordjournals.org/cgi/content/abstract/8/0/plv139

Zhang L, Chen F, Zhang Z, Chen Y and Wang J (2016) Synthesis and biological evaluation of a novel artesunate–podophyllotoxin conjugate as anticancer agent. Bioorganic & Medicinal Chemistry Letters 26, 38-42. //www.sciencedirect.com/science/article/pii/S0960894X1530250X

(2015) P A2 - Hodgson, Ernest. In ‘Dictionary of Toxicology (Third Edition)’ (Ed.^(Eds Roe RM, Mailman RB, et al.) pp. 263-294. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780124201699000163

Avendaño C and Menéndez JC (2015) Chapter 7 - Other Anticancer Drugs Targeting DNA and DNA-Associated Enzymes. In ‘Medicinal Chemistry of Anticancer Drugs (Second Edition)’ (Ed.^(Eds  pp. 273-323. (Elsevier: Boston). //www.sciencedirect.com/science/article/pii/B9780444626493000077

Barba FJ, Parniakov O, et al. (2015) Current applications and new opportunities for the use of pulsed electric fields in food science and industry. Food Research International 77, Part 4, 773-798. //www.sciencedirect.com/science/article/pii/S0963996915301897

Benarba B, Belabid L, Righi K, Bekkar Aa, Elouissi M, Khaldi A and Hamimed A (2015) Ethnobotanical study of medicinal plants used by traditional healers in Mascara (North West of Algeria). Journal of Ethnopharmacology 175, 626-637. //www.sciencedirect.com/science/article/pii/S0378874115301550

Bonnez W (2015) 146 - Papillomaviruses A2 - Bennett, John E. In ‘Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases (Eighth Edition)’ (Ed.^(Eds Dolin R and Blaser MJ) pp. 1794-1806.e4. (Content Repository Only!: Philadelphia). //www.sciencedirect.com/science/article/pii/B9781455748013001466

Calvo-Flores FG, Dobado JA, Isac-García J and Martín-MartíNez FJ (2015) Biological Properties of Lignans. In ‘Lignin and Lignans as Renewable Raw Materials’ (Ed.^(Eds  pp. 369-454. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118682784.ch11

Calvo-Flores FG, Dobado JA, Isac-García J and Martín-MartíNez FJ (2015) Structure and Chemical Properties of Lignans. In ‘Lignin and Lignans as Renewable Raw Materials’ (Ed.^(Eds  pp. 313-368. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118682784.ch10

Carod Artal FJ (2015) Chapter 23 - Adverse Neurological Effects Caused by the Ingestion of Plants, Seeds, and Fruits A2 - Watson, Ronald Ross. In ‘Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease’ (Ed.^(Eds Preedy VR) pp. 215-219. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780124114623000230

Chattopadhyay N and Maurya R (2015) Herbal Medicine. In ‘Reference Module in Biomedical Sciences’ (Ed.^(Eds  pp. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780128012383050613

Gnabre J, Bates R and Huang RC (2015) Creosote bush lignans for human disease treatment and prevention: Perspectives on combination therapy. Journal of Traditional and Complementary Medicine 5, 119-126. //www.sciencedirect.com/science/article/pii/S2225411014000388

Hao DC, Gu X-J and Xiao PG (2015) 2 - High-throughput sequencing in medicinal plant transcriptome studies. In ‘Medicinal Plants’ (Ed.^(Eds  pp. 49-96. (Woodhead Publishing). //www.sciencedirect.com/science/article/pii/B9780081000854000025

Huynh Cong L, Dauwe R, et al. (2015) Kinetics of glucosylated and non-glucosylated aryltetralin lignans in Linum hairy root cultures. Phytochemistry 115, 70-78. //www.sciencedirect.com/science/article/pii/S0031942215000345

Ida TY, Harder LD and Kudo G (2015) The consequences of demand-driven seed provisioning for sexual differences in reproductive investment in Thalictrum occidentale (Ranunculaceae). Journal of Ecology 103, 269-280. http://dx.doi.org/10.1111/1365-2745.12330

Jullian-Pawlicki N, Lequart-Pillon M, Huynh-Cong L, Lesur D, Cailleu D, Mesnard F, Laberche JC, Gontier E and Boitel-Conti M (2015) Arylnaphthalene and aryltetralin-type lignans in hairy root cultures of Linum perenne, and the stereochemistry of 6-methoxypodophyllotoxin and one diastereoisomer by HPLC-MS and NMR spectroscopy. Phytochemical Analysis 26, 310-319. http://dx.doi.org/10.1002/pca.2565

Karadeniz A, Alexie G, Greten HJ, Andersch K and Efferth T (2015) Cytotoxicity of medicinal plants of the West-Canadian Gwich׳in Native Americans towards sensitive and multidrug-resistant cancer cells. Journal of Ethnopharmacology 168, 191-200. //www.sciencedirect.com/science/article/pii/S0378874115002044

Kitagawa RR, Vilegas W, Varanda EA and Raddi MSG (2015) Evaluation of mutagenicity and metabolism-mediated cytotoxicity of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin from Paepalanthus latipes. Revista Brasileira de Farmacognosia 25, 16-21. //www.sciencedirect.com/science/article/pii/S0102695X15000320

Kumar P, Pal T, Sharma N, Kumar V, Sood H and Chauhan RS (2015) Expression analysis of biosynthetic pathway genes vis-à-vis podophyllotoxin content in Podophyllum hexandrum Royle. Protoplasma. 252, 1253-1262. http://dx.doi.org/10.1007/s00709-015-0757-x

Laishram S, Moirangthem DS, Borah JC, Pal BC, Suman P, Gupta SK, Kalita MC and Talukdar NC (2015) Chrysin rich Scutellaria discolor Colebr. induces cervical cancer cell death via the induction of cell cycle arrest and caspase-dependent apoptosis. Life Sciences 143, 105-113. //www.sciencedirect.com/science/article/pii/S0024320515300618

Liu Y-Q, Tian J, Qian K, Zhao X-B, Morris-Natschke SL, Yang L, Nan X, Tian X and Lee K-H (2015) Recent Progress on C-4-Modified Podophyllotoxin Analogs as Potent Antitumor Agents. Medicinal Research Reviews 35, 1-62. http://dx.doi.org/10.1002/med.21319

Mandal SC, Mandal V and Das AK (2015) Chapter 4 - What All Should Know about Plant Drugs. In ‘Essentials of Botanical Extraction’ (Ed.^(Eds  pp. 35-61. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128023259000045

Molina G, Pelissari FM, Pessoa MG and Pastore GM (2015) Bioactive compounds obtained through biotechnology. In ‘Biotechnology of Bioactive Compounds’ (Ed.^(Eds  pp. 433-462. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118733103.ch17

Nag A, Ahuja PS and Sharma RK (2015) Genetic diversity of high-elevation populations of an endangered medicinal plant. AoB Plants 7, plu076-. http://aobpla.oxfordjournals.org/cgi/content/abstract/7/0/plu076

Negreira N, López de Alda M and Barceló D (2015) Degradation of the cytostatic etoposide in chlorinated water by liquid chromatography coupled to quadrupole-Orbitrap mass spectrometry: Identification and quantification of by-products in real water samples. Science of The Total Environment 506–507, 36-45. //www.sciencedirect.com/science/article/pii/S0048969714015587

Newman DJ, Cragg GM and Kingston DGI (2015) Chapter 5 - Natural Products as Pharmaceuticals and Sources for Lead Structures*. In ‘The Practice of Medicinal Chemistry (Fourth Edition)’ (Ed.^(Eds  pp. 101-139. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780124172050000055

Renouard S, Corbin C, et al. (2015) Aerial parts of Callitris species as a rich source of deoxypodophyllotoxin. Industrial Crops and Products 63, 53-57. //www.sciencedirect.com/science/article/pii/S0926669014006736

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Cieckiewicz E, Angenot L, Gras T, Kiss R and Frédérich M (2012) Potential anticancer activity of young Carpinus betulus leaves. Phytomedicine 19, 278-283. http://www.sciencedirect.com/science/article/pii/S0944711311004600

Cragg GM, Grothaus PG and Newman DJ (2012) Natural Products in Drug Discovery: Recent Advances. In ‘Plant Bioactives and Drug Discovery’ (Ed.^(Eds  pp. 1-42. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118260005.ch1

Flamini G (2012) Chapter 13 - Natural Herbicides as a Safer and More Environmentally Friendly Approach to Weed Control: A Review of the Literature Since 2000. In ‘Studies in Natural Products Chemistry’ (Ed.^(Eds Atta ur R) pp. 353-396. (Elsevier). //www.sciencedirect.com/science/article/pii/B9780444595300000137

Guerram M, Jiang Z-Z and Zhang L-Y (2012) Podophyllotoxin, a medicinal agent of plant origin: past, present and future. Chinese Journal of Natural Medicines 10, 161-169. http://www.sciencedirect.com/science/article/pii/S1875536412600351

Guo YX, Han J, Zhang DY, Wang LH and Zhou LL (2012) An ammonium sulfate/ethanol aqueous two-phase system combined with ultrasonication for the separation and purification of lithospermic acid B from Salvia miltiorrhiza Bunge. Ultrasonics Sonochemistry 19, 719-724. http://www.sciencedirect.com/science/article/pii/S1350417711002690

Hata N, Hayashi Y, Okazawa A, Ono E, Satake H and Kobayashi A (2012) Effect of photoperiod on growth of the plants, and sesamin content and CYP81Q1 gene expression in the leaves of sesame (Sesamum indicum L.). Environmental and Experimental Botany 75, 212-219. http://www.sciencedirect.com/science/article/pii/S0098847211001675

Herschthal J, McLeod MP and Zaiac M (2012) Management of ungual warts. Dermatologic Therapy 25, 545-550. http://dx.doi.org/10.1111/j.1529-8019.2012.01509.x

Hougen KE and Matlack GR (2012) Long-term effects in vegetation and soils at two 19th century iron furnace sites in southeastern Ohio, USA. Forest Ecology and Management 269, 279-292. http://www.sciencedirect.com/science/article/pii/S0378112712000047

James OT and Myles EL (2012) Abstract A5: Cytotoxic Extracts of Ethnomedicinal Plants: Podophyllum peltatum (Mayapple) and Echinacea angustifolia. Cancer Res. 72, A5-. http://cancerres.aacrjournals.org/cgi/content/abstract/72/2_Supplement/A5

Kamal A, Suresh P, Ramaiah MJ, Mallareddy A, Imthiajali S, Pushpavalli SNCVL, Lavanya A and Pal-Bhadra M (2012) Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4′-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents. Bioorganic & Medicinal Chemistry 20, 2054-2066. http://www.sciencedirect.com/science/article/pii/S0968089612000697

Kim K-W, Moinuddin SGA, Atwell KM, Costa MA, Davin LB and Lewis NG (2012) Opposite Stereoselectivities of Dirigent Proteins in Arabidopsis and Schizandra Species. J. Biol. Chem. 287, 33957-33972. http://www.jbc.org/cgi/content/abstract/287/41/33957

Kim Y, Jung HJ and Kwon HJ (2012) A natural small molecule voacangine inhibits angiogenesis both in vitro and in vivo. Biochemical and Biophysical Research Communications 417, 330-334. http://www.sciencedirect.com/science/article/pii/S0006291X11021309

Kingston DGI and Newman DJ (2012) Natural Products as Anticancer Agents. In ‘Natural Products in Chemical Biology’ (Ed.^(Eds  pp. 325-349. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch13

Kusari S, Hertweck C and Spiteller M (2012) Chemical Ecology of Endophytic Fungi: Origins of Secondary Metabolites. Chemistry & Biology 19, 792-798. http://www.sciencedirect.com/science/article/pii/S1074552112001998

Loew D, Beer A-M and Kluge P (2012) 8 - Phytotherapie. In ‘Leitfaden Naturheilverfahren - Für die ärztliche Praxis’ (Ed.^(Eds  pp. 155-216. (Urban & Fischer: Munich). //www.sciencedirect.com/science/article/pii/B9783437561030100081

Marosi C (2012) Chapter 57 - Complications of chemotherapy in neuro-oncology. In ‘Handbook of Clinical Neurology’ (Ed.^(Eds Wolfgang G and Riccardo S) pp. 873-885. (Elsevier). http://www.sciencedirect.com/science/article/pii/B978044453502300029X

Meyer RS, DuVal AE and Jensen HR (2012) Patterns and processes in crop domestication: an historical review and quantitative analysis of 203 global food crops. New Phytologist 196, 29-48. http://dx.doi.org/10.1111/j.1469-8137.2012.04253.x

Ming Q, Han T, Li W, Zhang Q, Zhang H, Zheng C, Huang F, Rahman K and Qin L (2012) Tanshinone IIA and tanshinone I production by Trichoderma atroviride D16, an endophytic fungus in Salvia miltiorrhiza. Phytomedicine 19, 330-333. http://www.sciencedirect.com/science/article/pii/S0944711311004843

Minnis AM, McTaggart AR, Rossman AY and Aime MC (2012) Taxonomy of mayapple rust: the genus Allodus resurrected. Mycologia 104, 942-950. http://www.mycologia.org/cgi/content/abstract/104/4/942

Moore JE, Franklin SB, Wein G and Collins BS (2012) Long-term population demography of Trillium recurvatum on loess bluffs in western Tennessee, USA. AoB Plants 2012, pls015-. http://aobpla.oxfordjournals.org/cgi/content/abstract/2012/0/pls015

MOSBY TT, COSGROVE M, SARKARDEI S, PLATT KL and KAINA B (2012) Nutrition in Adult and Childhood Cancer: Role of Carcinogens and Anti-carcinogens. Anticancer Res 32, 4171-4192. http://ar.iiarjournals.org/cgi/content/abstract/32/10/4171

Oborny B, Mony C and Herben T (2012) From virtual plants to real communities: A review of modelling clonal growth. Ecological Modelling 234, 3-19. http://www.sciencedirect.com/science/article/pii/S0304380012001172

Olapade O and Pung K (2012) Plant-associated bacterial populations on native and invasive plant species: comparisons between 2 freshwater environments. Can J Microbiol 58, 767-75.

Olapade OA and Pung K (2012) Plant-associated bacterial populations on native and invasive plant species: comparisons between 2 freshwater environments. Canadian journal of microbiology. 58, 767-775. http://dx.doi.org/10.1139/w2012-053

Panchen ZA, Primack RB, Anisko T and Lyons RE (2012) Herbarium specimens, photographs, and field observations show Philadelphia area plants are responding to climate change. Am. J. Botany 99, 751-756. http://www.amjbot.org/cgi/content/abstract/99/4/751

Pennisi SV and van Iersel MW (2012) Quantification of Carbon Assimilation of Plants in Simulated and In Situ Interiorscapes. HortScience 47, 468-476. http://hortsci.ashspublications.org/cgi/content/abstract/47/4/468

Perez B, Paquette N, Paidassi H, Zhai B, White K, Skvirsky R, Lacy-Hulbert A and Stuart LM (2012) Apoptotic Cells Can Deliver Chemotherapeutics to Engulfing Macrophages and Suppress Inflammatory Cytokine Production. J. Biol. Chem. 287, 16029-16036. http://www.jbc.org/cgi/content/abstract/287/19/16029

Rathee P, Rathee D, Rathee D and Rathee S (2012) In-vitro cytotoxic activity of β-Sitosterol triacontenate isolated from Capparis decidua (Forsk.) Edgew. Asian Pacific Journal of Tropical Medicine 5, 225-230. http://www.sciencedirect.com/science/article/pii/S1995764512600297

Saslis-Lagoudakis CH, Savolainen V, Williamson EM, Forest F, Wagstaff SJ, Baral SR, Watson MF, Pendry CA and Hawkins JA (2012) Phylogenies reveal predictive power of traditional medicine in bioprospecting. PNAS 109, 15835-15840. http://www.pnas.org/cgi/content/abstract/109/39/15835

Steingroewer J, Bley T, Georgiev V, Ivanov I, Lenk F, Marchev A and Pavlov A (2012) Bioprocessing of differentiated plant in vitro systems. Engineering in Life Sciences, n/a-n/a. http://dx.doi.org/10.1002/elsc.201100226

Tack AJM, Thrall PH, Barrett LG, Burdon JJ and Laine AL (2012) Variation in infectivity and aggressiveness in space and time in wild host–pathogen systems: causes and consequences. Journal of Evolutionary Biology 25, 1918-1936. http://dx.doi.org/10.1111/j.1420-9101.2012.02588.x

Tylewicz U, Lundin P, Cocola L, Dymek K, Rocculi P, Svanberg S, Dejmek P and G?mez Galindo F (2012) Gas in Scattering Media Absorption Spectroscopy (GASMAS) Detected Persistent Vacuum in Apple Tissue After Vacuum Impregnation. Food biophysics. 7, 28-34. http://dx.doi.org/10.1007/s11483-011-9239-7

Wang W, Ortiz RDC, et al. (2012) Menispermaceae and the diversification of tropical rainforests near the Cretaceous–Paleogene boundary. New Phytologist 195, 470-478. http://dx.doi.org/10.1111/j.1469-8137.2012.04158.x

Woo CC, Kumar AP, Sethi G and Tan KHB (2012) Thymoquinone: Potential cure for inflammatory disorders and cancer. Biochemical Pharmacology 83, 443-451. http://www.sciencedirect.com/science/article/pii/S0006295211007350

Zhao S and Baik O (2012) Application of ultrasound as pretreatment for extraction of podophyllotoxin from rhizomes of Podophyllum peltatum. Ultrason Sonochem 19, 22-31.

Zhao S and Baik OD (2012) Application of ultrasound as pretreatment for extraction of podophyllotoxin from rhizomes of Podophyllum peltatum. Ultrasonics Sonochemistry 19, 22-31. http://www.sciencedirect.com/science/article/pii/S1350417711001052

 

 

References 1901-2013 (and links to abstracts):
[Number of papers mentioning Podophyllum peltatum: 896; Any undated papers have been included at the end]

 

Kumar A, Kumar V, Malhotra SV, Antonio AE (2013) Abstract 2476: Synthesis of novel aza-podophyllotoxins derivatives substituted at ring-A and their activities on NCI-60 human tumor cell line. Cancer Res. 73, 2476-. http://cancerres.aacrjournals.org

Marques JV, Kim K-W, Lee C, Costa MA, May GD, Crow JA, Davin LB, Lewis NG (2013) Next Generation Sequencing in Predicting Gene Function in Podophyllotoxin Biosynthesis. J. Biol. Chem. 288, 466-79. http://www.jbc.org/cgi/content/abstract/288/1/466

Xiong Y-Z, Fang Q, Huang S-Q (2013) Pollinator scarcity drives the shift to delayed selfing in Himalayan mayapple Podophyllum hexandrum (Berberidaceae). AoB Plants, plt037. http://aobpla.oxfordjournals.org/cgi/content/abstract/plt037v1

Zhi X-y, Yang C, Zhang R, Hu Y, Ke Y-z, Xu H (2013) Natural products-based insecticidal agents 13. Semisynthesis and insecticidal activity of novel phenazine derivatives of 4β-acyloxypodophyllotoxin modified in the E-ring against Mythimna separata Walker in vivo. Industrial Crops and Products 42, 520-6. http://www.sciencedirect.com/science/article/pii/S0926669012003676

Anonymous (2012) Index. In ‘Handbook of Clinical Neurology’. (Eds Michael J. Aminoff FB and Dick FS) pp. I1-I16. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444521385000712

Abdullah SH, Zhao S, Mittal GS, Baik O-D (2012) Extraction of podophyllotoxin from Podophyllum peltatum using pulsed electric field treatment. Separation and Purification Technology 93, 92-7. http://www.sciencedirect.com/science/article/pii/S1383586612002109

Abrams JN, Zhao Q, Ghiviriga I, Minaruzzaman (2012) Palladium(II)-catalyzed enyne cyclization strategies toward the podophyllotoxin ring system. Tetrahedron 68, 423-8. http://www.sciencedirect.com/science/article/pii/S0040402011017145

Barniske A-M, Borsch T, MÜLler K, Krug M, Worberg A, Neinhuis C, Quandt D (2012) Phylogenetics of early branching eudicots: Comparing phylogenetic signal across plastid introns, spacers, and genes. Journal of Systematics and Evolution 50, 85-108. http://dx.doi.org/10.1111/j.1759-6831.2012.00181.x

Bittebiere AK, Mony C, Clément B, Garbey M (2012) Modeling competition between plants using an Individual Based Model: Methods and effects on the growth of two species with contrasted growth forms. Ecological Modelling 234, 38-50. http://www.sciencedirect.com/science/article/pii/S0304380011003085

Bradberry S, Vale A (2012) Plants. Medicine 40, 151-3. http://www.sciencedirect.com/science/article/pii/S1357303911003318

Burrows GE, Tyrl RJ (2012) Berberidaceae Juss. In ‘Toxic Plants of North America’ pp. 257-65. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781118413425.ch14

Burrows GE, Tyrl RJ (2012) Introduction. In ‘Toxic Plants of North America’ pp. 3-10. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781118413425.ch1

Burrows GE, Tyrl RJ (2012) Index. In ‘Toxic Plants of North America’ pp. 1308-83. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781118413425.index

Cieckiewicz E, Angenot L, Gras T, Kiss R, Frédérich M (2012) Potential anticancer activity of young Carpinus betulus leaves. Phytomedicine 19, 278-83. http://www.sciencedirect.com/science/article/pii/S0944711311004600

Cragg GM, Grothaus PG, Newman DJ (2012) Natural Products in Drug Discovery: Recent Advances. In ‘Plant Bioactives and Drug Discovery’ pp. 1-42. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118260005.ch1

Guerram M, Jiang Z-Z, Zhang L-Y (2012) Podophyllotoxin, a medicinal agent of plant origin: past, present and future. Chinese Journal of Natural Medicines 10, 161-9. http://www.sciencedirect.com/science/article/pii/S1875536412600351

Guo YX, Han J, Zhang DY, Wang LH, Zhou LL (2012) An ammonium sulfate/ethanol aqueous two-phase system combined with ultrasonication for the separation and purification of lithospermic acid B from Salvia miltiorrhiza Bunge. Ultrasonics Sonochemistry 19, 719-24. http://www.sciencedirect.com/science/article/pii/S1350417711002690

Hata N, Hayashi Y, Okazawa A, Ono E, Satake H, Kobayashi A (2012) Effect of photoperiod on growth of the plants, and sesamin content and CYP81Q1 gene expression in the leaves of sesame (Sesamum indicum L.). Environmental and Experimental Botany 75, 212-9. http://www.sciencedirect.com/science/article/pii/S0098847211001675

Hougen KE, Matlack GR (2012) Long-term effects in vegetation and soils at two 19th century iron furnace sites in southeastern Ohio, USA. Forest Ecology and Management 269, 279-92. http://www.sciencedirect.com/science/article/pii/S0378112712000047

James OT, Myles EL (2012) Abstract A5: Cytotoxic Extracts of Ethnomedicinal Plants: Podophyllum peltatum (Mayapple) and Echinacea angustifolia. Cancer Res. 72, A5-. http://cancerres.aacrjournals.org/cgi/content/abstract/72/2_Supplement/A5

Kamal A, Suresh P, Ramaiah MJ, Mallareddy A, Imthiajali S, Pushpavalli SNCVL, Lavanya A, Pal-Bhadra M (2012) Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4′-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents. Bioorganic & Medicinal Chemistry 20, 2054-66. http://www.sciencedirect.com/science/article/pii/S0968089612000697

Kim K-W, Moinuddin SGA, Atwell KM, Costa MA, Davin LB, Lewis NG (2012) Opposite Stereoselectivities of Dirigent Proteins in Arabidopsis and Schizandra Species. J. Biol. Chem. 287, 33957-72. http://www.jbc.org/cgi/content/abstract/287/41/33957

Kim Y, Jung HJ, Kwon HJ (2012) A natural small molecule voacangine inhibits angiogenesis both in vitro and in vivo. Biochemical and Biophysical Research Communications 417, 330-4. http://www.sciencedirect.com/science/article/pii/S0006291X11021309

Kingston DGI, Newman DJ (2012) Natural Products as Anticancer Agents. In ‘Natural Products in Chemical Biology’ pp. 325-49. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118391815.ch13

Kumar M, Shanmugham A, Prabha S, Adhisivam B, Narayanan P, Biswal N (2012) Permanent Neurological Sequelae Following Accidental Podophyllin Ingestion. J Child Neurol 27, 209-10. http://jcn.sagepub.com/cgi/content/abstract/27/2/209

Kusari S, Hertweck C, Spiteller M (2012) Chemical Ecology of Endophytic Fungi: Origins of Secondary Metabolites. Chemistry & Biology 19, 792-8. http://www.sciencedirect.com/science/article/pii/S1074552112001998

Marosi C (2012) Chapter 57 - Complications of chemotherapy in neuro-oncology. In ‘Handbook of Clinical Neurology’. (Eds Wolfgang G and Riccardo S) pp. 873-85. (Elsevier). http://www.sciencedirect.com/science/article/pii/B978044453502300029X

Meyer RS, DuVal AE, Jensen HR (2012) Patterns and processes in crop domestication: an historical review and quantitative analysis of 203 global food crops. New Phytologist 196, 29-48. http://dx.doi.org/10.1111/j.1469-8137.2012.04253.x

Ming Q, Han T, Li W, Zhang Q, Zhang H, Zheng C, Huang F, Rahman K, Qin L (2012) Tanshinone IIA and tanshinone I production by Trichoderma atroviride D16, an endophytic fungus in Salvia miltiorrhiza. Phytomedicine 19, 330-3. http://www.sciencedirect.com/science/article/pii/S0944711311004843

Minnis AM, McTaggart AR, Rossman AY, Aime MC (2012) Taxonomy of mayapple rust: the genus Allodus resurrected. Mycologia 104, 942-50. http://www.mycologia.org/cgi/content/abstract/104/4/942

Moore JE, Franklin SB, Wein G, Collins BS (2012) Long-term population demography of Trillium recurvatum on loess bluffs in western Tennessee, USA. AoB Plants 2012, pls015-. http://aobpla.oxfordjournals.org/cgi/content/abstract/2012/0/pls015

MOSBY TT, COSGROVE M, SARKARDEI S, PLATT KL, KAINA B (2012) Nutrition in Adult and Childhood Cancer: Role of Carcinogens and Anti-carcinogens. Anticancer Res 32, 4171-92. http://ar.iiarjournals.org/cgi/content/abstract/32/10/4171

Oborny B, Mony C, Herben T (2012) From virtual plants to real communities: A review of modelling clonal growth. Ecological Modelling 234, 3-19. http://www.sciencedirect.com/science/article/pii/S0304380012001172

Olapade O, Pung K (2012) Plant-associated bacterial populations on native and invasive plant species: comparisons between 2 freshwater environments. Can J Microbiol 58, 767-75.

Panchen ZA, Primack RB, Anisko T, Lyons RE (2012) Herbarium specimens, photographs, and field observations show Philadelphia area plants are responding to climate change. Am. J. Botany 99, 751-6. http://www.amjbot.org/cgi/content/abstract/99/4/751

Pennisi SV, van Iersel MW (2012) Quantification of Carbon Assimilation of Plants in Simulated and In Situ Interiorscapes. HortScience 47, 468-76. http://hortsci.ashspublications.org/cgi/content/abstract/47/4/468

Perez B, Paquette N, Paidassi H, Zhai B, White K, Skvirsky R, Lacy-Hulbert A, Stuart LM (2012) Apoptotic Cells Can Deliver Chemotherapeutics to Engulfing Macrophages and Suppress Inflammatory Cytokine Production. J. Biol. Chem. 287, 16029-36. http://www.jbc.org/cgi/content/abstract/287/19/16029

Prieto I, Armas C, Pugnaire FI (2012) Water release through plant roots: new insights into its consequences at the plant and ecosystem level. New Phytologist 193, 830-41. http://dx.doi.org/10.1111/j.1469-8137.2011.04039.x

Rathee P, Rathee D, Rathee D, Rathee S (2012) In-vitro cytotoxic activity of β-Sitosterol triacontenate isolated from Capparis decidua (Forsk.) Edgew. Asian Pacific Journal of Tropical Medicine 5, 225-30. http://www.sciencedirect.com/science/article/pii/S1995764512600297

Saslis-Lagoudakis CH, Savolainen V, Williamson EM, Forest F, Wagstaff SJ, Baral SR, Watson MF, Pendry CA, Hawkins JA (2012) Phylogenies reveal predictive power of traditional medicine in bioprospecting. PNAS 109, 15835-40. http://www.pnas.org/cgi/content/abstract/109/39/15835

Spyreas G, Meiners SJ, Matthews JW, Molano-Flores B (2012) Successional trends in Floristic Quality. Journal of Applied Ecology 49, 339-48. http://dx.doi.org/10.1111/j.1365-2664.2011.02100.x

Steingroewer J, Bley T, Georgiev V, Ivanov I, Lenk F, Marchev A, Pavlov A (2012) Bioprocessing of differentiated plant in vitro systems. Engineering in Life Sciences, n/a-n/a. http://dx.doi.org/10.1002/elsc.201100226

Tack AJM, Thrall PH, Barrett LG, Burdon JJ, Laine AL (2012) Variation in infectivity and aggressiveness in space and time in wild host–pathogen systems: causes and consequences. Journal of Evolutionary Biology 25, 1918-36. http://dx.doi.org/10.1111/j.1420-9101.2012.02588.x

Wang W, Ortiz RDC, et al. (2012) Menispermaceae and the diversification of tropical rainforests near the Cretaceous–Paleogene boundary. New Phytologist 195, 470-8. http://dx.doi.org/10.1111/j.1469-8137.2012.04158.x

Woo CC, Kumar AP, Sethi G, Tan KHB (2012) Thymoquinone: Potential cure for inflammatory disorders and cancer. Biochemical Pharmacology 83, 443-51. http://www.sciencedirect.com/science/article/pii/S0006295211007350

Zhao J (2012) Nutraceuticals–Functional Foods for Improving Health and Preventing Disease. In ‘Pharmaceutical Biotechnology’ pp. 599-628. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527632909.ch23

Zhao S, Baik O (2012) Application of ultrasound as pretreatment for extraction of podophyllotoxin from rhizomes of Podophyllum peltatum. Ultrason Sonochem 19, 22-31.

Zhao S, Baik OD (2012) Application of ultrasound as pretreatment for extraction of podophyllotoxin from rhizomes of Podophyllum peltatum. Ultrasonics Sonochemistry 19, 22-31. http://www.sciencedirect.com/science/article/pii/S1350417711001052

Zhao S, Baik OD (2012) Corrigendum to “Application of ultrasound as pretreatment for extraction of podophyllotoxin from rhizomes of Podophyllum peltatum” [Ultrasonics Sonochemistry 19 (2011) 22–31]. Ultrasonics Sonochemistry 19, 376. http://www.sciencedirect.com/science/article/pii/S135041771100188X

Zheljazkov VD, Cantrell CL, Donega MA, Astatkie T, Heidel B (2012) Podophyllotoxin Concentration in Junipers in the Big Horn Mountains in Wyoming. HortScience 47, 1696-7. http://hortsci.ashspublications.org/cgi/content/abstract/47/12/1696

Anonymous (2011) Index. In ‘Tropical Infectious Diseases: Principles, Pathogens and Practice (Third Edition)’ pp. 1082-130. (W.B. Saunders: Edinburgh). http://www.sciencedirect.com/science/article/pii/B9780702039355001440

Amos LA (2011) What tubulin drugs tell us about microtubule structure and dynamics. Seminars in Cell & Developmental Biology 22, 916-26. http://www.sciencedirect.com/science/article/pii/S1084952111001704

Avula B, Wang Y, Moraes R, Khan I (2011) Rapid analysis of lignans from leaves of Podophyllum peltatum L. samples using UPLC-UV-MS. Biomed Chromatogr.

Avula B, Wang Y-H, Moraes RM, Khan IA (2011) Rapid analysis of lignans from leaves of Podophyllum peltatum L. samples using UPLC-UV-MS. Biomedical Chromatography 25, 1230-6. http://dx.doi.org/10.1002/bmc.1595

Beattie AJ, Hay M, Magnusson B, de Nys R, Smeathers J, Vincent JFV (2011) Ecology and bioprospecting. Austral Ecology 36, 341-56. http://dx.doi.org/10.1111/j.1442-9993.2010.02170.x

Bonnez W, Lindeque G (2011) CHAPTER 80 - Human Papillomavirus Infections. In ‘Tropical Infectious Diseases: Principles, Pathogens and Practice (Third Edition)’ pp. 532-40. (W.B. Saunders: Edinburgh). http://www.sciencedirect.com/science/article/pii/B978070203935500080X

Burke DJ, Weintraub MN, Hewins CR, Kalisz S (2011) Relationship between soil enzyme activities, nutrient cycling and soil fungal communities in a northern hardwood forest. Soil Biology and Biochemistry 43, 795-803. http://www.sciencedirect.com/science/article/pii/S0038071710004839

Endress PK (2011) Evolutionary diversification of the flowers in angiosperms. Am. J. Botany 98, 370-96. http://www.amjbot.org/cgi/content/abstract/98/3/370

Figueiredo AC, Pedro LG (2011) Protocols for in vitro cultures and secondary metabolite analysis of aromatic and medicinal plants. S. Mohan Jain and Praveen K. Saxena (Eds), Humana Press, ISBN 978-1-60327-286-5. Flavour and Fragrance Journal 26, 70-. http://dx.doi.org/10.1002/ffj.2013

Gandin A, Gutjahr S, Dizengremel P, Lapointe L (2011) Source-sink imbalance increases with growth temperature in the spring geophyte Erythronium americanum. J. Exp. Bot. 62, 3467-79. http://jxb.oxfordjournals.org/cgi/content/abstract/62/10/3467

Giraud F, Greillier L (2011) Oncologie. Revue des Maladies Respiratoires Actualités 3, 40-8. http://www.sciencedirect.com/science/article/pii/S187712031170009X

Hendrawati O, Woerdenbag HJ, Michiels PJA, Aantjes HG, van Dam A, Kayser O (2011) Identification of lignans and related compounds in Anthriscus sylvestris by LC–ESI-MS/MS and LC-SPE–NMR. Phytochemistry 72, 2172-9. http://www.sciencedirect.com/science/article/pii/S003194221100375X

Herold J, Anderson MR, Bauer JT, Borowicz V, Anderson RC (2011) Comparison of the Effect of Early and Late Removal of Second-Year Garlic Mustard (Alliaria petiolata) on First-Year Plants and Deciduous Forest Spring and Summer Dominant Herbaceous Groundlayer Species in Central Illinois, USA. Ecological Rest. 29, 225-33. http://er.uwpress.org/cgi/content/abstract/29/3/225

Jacques FMB, Wang W, Ortiz RDC, Li H-L, Zhou Z-K, Chen Z-D (2011) Integrating fossils in a molecular-based phylogeny and testing them as calibration points for divergence time estimates in Menispermaceae. Journal of Systematics and Evolution 49, 25-49. http://dx.doi.org/10.1111/j.1759-6831.2010.00105.x

Kamal A, Ashwini Kumar B, Suresh P, Juvekar A, Zingde S (2011) Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents. Bioorganic & Medicinal Chemistry 19, 2975-9. http://www.sciencedirect.com/science/article/pii/S0968089611002112

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Mishra BB, Tiwari VK (2011) Natural products: An evolving role in future drug discovery. European Journal of Medicinal Chemistry 46, 4769-807. http://www.sciencedirect.com/science/article/pii/S0223523411005708

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Caplin SM, Steward FC (1952) Investigations on the Growth and Metabolism of Plant Cells: II. Variables affecting the Growth of Tissue Explants and the Development of a Quantitative Method using Carrot Root. Ann. Bot. 16, 219-34. http://aob.oxfordjournals.org/cgi/content/abstract/16/2/219

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Hall AF (1950) TREATMENT OF SENILE KERATOSES WITH PODOPHYLLIN. Arch Derm Syphilol 62, 362-9. http://archderm.ama-assn.org

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Cwalina GE, Jenkins GL (1938) A phytochemical study of ipomea pes-capræ. Journal of the American Pharmaceutical Association 27, 585-95. http://dx.doi.org/10.1002/jps.3080270713

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Viehoever A (1938) Evaluation of cathartics. Journal of the American Pharmaceutical Association 27, 668-71. http://dx.doi.org/10.1002/jps.3080270811

Viehoever A, Mack H (1938) Biochemistry of may apple root (podophyllum peltatum) I. Journal of the American Pharmaceutical Association 27, 632-43. http://dx.doi.org/10.1002/jps.3080270804

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Barkley WW (1936) Drug collecting and cultivation in Mississippi. Journal of the American Pharmaceutical Association 25, 1156-9. http://dx.doi.org/10.1002/jps.3080251218

Reddish GF (1936) Antiseptics: A comparative study of laboratory and practical tests. Journal of the American Pharmaceutical Association 25, 1117-22. http://dx.doi.org/10.1002/jps.3080251208

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Kaufmann BP (1934) Somatic mitoses of Drosophila melanogaster. Journal of Morphology 56, 125-55. http://dx.doi.org/10.1002/jmor.1050560107

Koshy TK (1934) CHROMOSOME STUDIES IN ALLIUM. Journal of the Royal Microscopical Society 54, 104-20. http://dx.doi.org/10.1111/j.1365-2818.1934.tb00327.x

Himmel WJ (1933) THE TROPOGRAPH AND ITS USE. Plant Physiology 8, 337-40. http://www.plantphysiol.org

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Borsche W, Niemann J (1932) Über Podophyllin. Justus Liebigs Annalen der Chemie 494, 126-42. http://dx.doi.org/10.1002/jlac.19324940113

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Kamal A, Suresh P, Ramaiah MJ, Mallareddy A, Imthiajali S, Pushpavalli SNCVL, Lavanya A, Pal-Bhadra M Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4′-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents. Bioorganic & Medicinal Chemistry 20, 2054-66. http://www.sciencedirect.com/science/article/pii/S0968089612000697

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Mishra BB, Tiwari VK Natural products: An evolving role in future drug discovery. European Journal of Medicinal Chemistry 46, 4769-807. http://www.sciencedirect.com/science/article/pii/S0223523411005708

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Reuter J, Wölfle U, Weckesser S, Schempp C Which plant for which skin disease? Part 1: Atopic dermatitis, psoriasis, acne, condyloma and herpes simplex. JDDG: Journal der Deutschen Dermatologischen Gesellschaft 8, 788-96. http://dx.doi.org/10.1111/j.1610-0387.2010.07496.x

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Grateful acknowledgment is made to the following: for plant names: Australian Plant Name Index, Australian National Herbarium http://www.anbg.gov.au/cpbr/databases/apni-search-full.html; ; The International Plant Names Index, Royal Botanic Gardens, Kew/Harvard University Herbaria/Australian National Herbarium http://www.ipni.org/index.html; Plants Database, United States Department of Agriculture, National Resources Conservation Service http://plants.usda.gov/;DJ Mabberley (1997) The Plant Book, Cambridge University Press (Second Edition); JH Wiersma and B Leon (1999) World Economic Plants, CRC Press; RJ Hnatiuk (1990) Census of Australian Vascular Plants, Australian Government Publishing Service; for information: Science Direct http://www.sciencedirect.com/; Wiley Online Library http://onlinelibrary.wiley.com/advanced/search; High Wire http://highwire.stanford.edu/cgi/search; Oxford Journals http://services.oxfordjournals.org/search.dtl; USDA National Agricultural Library http://agricola.nal.usda.gov/booleancube/booleancube_search_cit.html; for synonyms: The Plant List http://www.theplantlist.org/; for common names: http://en.wikipedia.org/wiki/Main_Page; etc.


All information is included in good faith but this website does not warrant or guarantee the accuracy of any information on these pages, nor does the website accept responsibility for any loss arising from the use of this information.  Views and opinions are those of the authors themselves.  Every effort has been made to respect copyright owners' rights. 


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Latest update March 2017 by: ANCW