Australian New Crops Info 2016
Supported by the Rural Industries Research and Development Corporation

Listing of Interesting Plants of the World:

Piper betel

 

 

This species is usually known as:

Piper betle

 

This species has no synonyms in The Plant List

 

Common names:

Betel Pepper, Betel Plant

 

 

Trends (five databases) 1901-2013:
[Number of papers mentioning Piper betel: 346]

 

Piper betel.jpg

 

Popularity of Piper betel over time
[Left-hand Plot: Plot of numbers of papers mentioning Piper betel (histogram and left hand axis scale of left-hand plot) and line of best fit, 1901 to 2013 (equation and % variation accounted for in box); Right-hand Plot: Plot of a proportional micro index, derived from numbers of papers mentioning Piper betel as a proportion (scaled by multiplying by one million) of the approximate total number of papers available in databases for that year (frequency polygon and left-hand axis scale of right-hand plot) and line of best fit, 1901 to 2013 (equation and % variation accounted for in box)] 

[For larger charts showing the numbers of papers that have mentioned this species over years, select this link; there are links to come back from there]

 

Keywords

[Total number of keywords included in the papers that mentioned this species: 1421]

 

betel quid (23), Areca nut (22), Antioxidant activity (19), oral cancer (17), Antioxidant (12), piper betle (10), smoking (10), Oxidative stress (9), reactive oxygen species (9), Hydroxychavicol (8), Lipid peroxidation (8), Piper betel (8), Alcohol (6), alcohol drinking (6), Areca (6), Arecoline (6), Betel (6), cadmium (6), Ethnobotany (6), Oral squamous cell carcinoma (6), oral submucous fibrosis (6), Phenolics (6), Ayurveda (5), betel nut (5), Betel nut chewing (5), Flavonoids (5), India (5), Manilkara zapota (5), Medicinal plants (5), Plant extracts (5), tobacco (5), Antimicrobial activity (4), antioxidants (4), apoptosis (4), Areca catechu (4), Bangladesh (4), betel leaf (4), betel quid chewing (4), DPPH (4), esophageal cancer (4), essential oils (4), Evolution (4), phenolic compounds (4), Phenols (4), Photosensitization (4), Safrole (4), Staphylococcus aureus (4), Taiwan (4), Tobacco consumption (4), tobacco smoking (4), upper aerodigestive cancer (4), age (3), allylpyrocatechol (3), ascorbic acid (3), betel chewing (3), Collagen (3), Cosmetics (3), Dependence (3), Free radicals (3), halitosis (3), IL-8 (3), leafy vegetables (3), Lipids (3), natural products (3), plant health (3), precancer (3), Protection (3), Quercetin (3), Rats (3), smokeless tobacco (3), streptozotocin (3), submucous fibrosis (3), turmeric (3), β-carotene (3), aesthetic value (2), Ag nanoparticles (2), alkaloids (2), allyl/propenyl phenol synthases (2), allylphenols (2), anatomical site (2), Antiallergic activity (2), Antiasthmatic plants (2), Antibacterial (2), Antifungal (2), Antifungal activity (2), Antinutrient (2), Anti-oxidant (2), Anti-oxidant agent (2), Antioxidant enzyme activities (2), Antiplatelet activity (2), Antitumour activity (2), Aqueous extract (2), areca chewing as addiction, sympathetic and GABAergic (2), Areca nut extracts (2), areca nuts of betel palm, as betel quid (2), areca quid (2), aromas (2), Arsenic (2), Asthma (2), bad breath (2), benzo[a]pyrene (2), betel-quid (2), Binucleated cells (2), bioactive plant constituents (2), Biochemical parameters (2).....

 

[If all keywords are not here (as indicated by .....), they can be accessed from this link; there are links to come back from there]

 

 

Most likely scope for crop use/product (%):
[Please note: When there are only a few papers mentioning a species, care should be taken with the interpretation of these crop use/product results; as well, a mention may relate to the use of a species, or the context in which it grows, rather than a product]

 

smoking (67.52), nut (18.19), chewing (3.55), cosmetics (2.27), beverage (1.04), flavouring/spice (0.98), timber (0.91), oilseed/fat (0.56), poison (0.55), weed (0.55).....

 

[To see the full list of crop use/product outcomes, from searching abstracts of the papers that have mentioned this species, select this link; details of the analysis process have also been included; there are links to come back from there]

 

 

Recent mentions of this species in the literature:
[since 2012, with links to abstracts; The references from 1901-2013 which have been used for the trend, keyword and crop use/product analyses below, are listed below these references]

 

Amin SA, Bhattacharya P, Basak S, Gayen S, Nandy A and Saha A (2017) Pharmacoinformatics study of Piperolactam A from Piper betle root as new lead for non steroidal anti fertility drug development. Computational Biology and Chemistry 67, 213-224. //www.sciencedirect.com/science/article/pii/S1476927115300475

Behl T and Kotwani A (2017) Proposed mechanisms of Terminalia catappa in hyperglycaemia and associated diabetic complications. Journal of Pharmacy and Pharmacology 69, 123-134. http://dx.doi.org/10.1111/jphp.12676

Branquinho LS, Santos JA, Cardoso CAL, Mota JdS, Junior UL, Kassuya CAL and Arena AC (2017) Anti-inflammatory and toxicological evaluation of essential oil from Piper glabratum leaves. Journal of Ethnopharmacology 198, 372-378. //www.sciencedirect.com/science/article/pii/S0378874116306444

Huang X, Liu Z, et al. (2017) Betel quid chewing alters functional connectivity in frontal and default networks: A resting-state fMRI study. Journal of Magnetic Resonance Imaging 45, 157-166. http://dx.doi.org/10.1002/jmri.25322

(2016) Index A2 - Sun, Gang. In Antimicrobial Textiles (Ed.^(Eds  pp. 337-351. (Woodhead Publishing). //www.sciencedirect.com/science/article/pii/B9780081005767180010

(2016) Issue Information. Drug Testing and Analysis 8, 991-995. http://dx.doi.org/10.1002/dta.2089

Amarowicz R (2016) Natural phenolic compounds protect LDL against oxidation. European Journal of Lipid Science and Technology 118, 677-679. http://dx.doi.org/10.1002/ejlt.201600077

Anugrahwati M, Purwaningsih T, Rustina, Manggalarini JA, Alnavis NB, Wulandari DN and Pranowo HD (2016) Extraction of Ethanolic Extract of Red Betel Leaves and Its Cytotoxicity Test on HeLa Cells. Procedia Engineering 148, 1402-1407. //www.sciencedirect.com/science/article/pii/S1877705816310372

Aumeeruddy-Elalfi Z, Gurib-Fakim A and Mahomoodally MF (2016) Chapter 13 - Antimicrobial and Antibiotic Potentiating Activity of Essential Oils From Tropical Medicinal Herbs and Spices A2 - Kon, Kateryna. In Antibiotic Resistance (Ed.^(Eds Rai M) pp. 271-289. (Academic Press). //www.sciencedirect.com/science/article/pii/B9780128036426000137

Chinsembu KC (2016) Plants and other natural products used in the management of oral infections and improvement of oral health. Acta Tropica 154, 6-18. //www.sciencedirect.com/science/article/pii/S0001706X1530142X

Cox S, Ullah M and Zoellner H (2016) Chapter 78 - Oral and Systemic Health Effects of Compulsive Areca Nut Use A2 - Preedy, Victor R. In Neuropathology of Drug Addictions and Substance Misuse (Ed.^(Eds  pp. 785-793. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780128006344000780

Das S, Parida R, Sriram Sandeep I, Nayak S and Mohanty S (2016) Biotechnological intervention in betelvine (Piper betle L.): A review on recent advances and future prospects. Asian Pacific Journal of Tropical Medicine 9, 938-946. //www.sciencedirect.com/science/article/pii/S1995764516301687

Dey AK, Sharma M and Meshram MR (2016) Image Processing Based Leaf Rot Disease, Detection of Betel Vine (Piper BetleL.). Procedia Computer Science 85, 748-754. //www.sciencedirect.com/science/article/pii/S1877050916306123

El-Newary SA (2016) The hypolipidemic effect of Portulaca oleracea L. stem on hyperlipidemic Wister Albino rats. Annals of Agricultural Sciences 61, 111-124. //www.sciencedirect.com/science/article/pii/S0570178316000142

Franke AA, Li X and Lai JF (2016) Pilot study of the pharmacokinetics of betel nut and betel quid biomarkers in saliva, urine, and hair of betel consumers. Drug Testing and Analysis 8, 1095-1099. http://dx.doi.org/10.1002/dta.1912

Ghazali NA, Elmy A, Yuen LC, Sani NZ, Das S, Suhaimi F, Yusof R, Yusoff NH and Thent ZC (2016) Piper betel leaves induces wound healing activity via proliferation of fibroblasts and reducing 11β hydroxysteriod dehydrogenase-1 expression in diabetic rat. Journal of Ayurveda and Integrative Medicine 7, 198-208. //www.sciencedirect.com/science/article/pii/S0975947616301383

Irfan M, Ahmad T, Moniruzzaman MM, Abdullah BB and Bhattacharjee S (2016) Ionic Liquid Mediated Biosynthesis of Gold Nanoparticles Using Elaeis Guineensis (Oil Palm) Leaves Extract. Procedia Engineering 148, 568-572. //www.sciencedirect.com/science/article/pii/S1877705816309791

Madathil SA, Rousseau M-C, Wynant W, Schlecht NF, Netuveli G, Franco EL and Nicolau B (2016) Nonlinear association between betel quid chewing and oral cancer: Implications for prevention. Oral Oncology 60, 25-31. //www.sciencedirect.com/science/article/pii/S1368837516300859

Milgrom P, Tut OK, Gallen M, Mancl L, Spillane N, Chi DL and Ramsay DS (2016) Symptoms with betel nut and betel nut with tobacco among Micronesian youth. Addictive Behaviors 53, 120-124. //www.sciencedirect.com/science/article/pii/S030646031530040X

Mujaffar S and Lee Loy A (2016) The rehydration behavior of microwave-dried amaranth (Amaranthus dubius) leaves. Food Science & Nutrition, n/a-n/a. http://dx.doi.org/10.1002/fsn3.406

Roopan SM and Elango G (2016) Chapter 15 - Self-assembly of transition metal nanoparticles using marine sources* A2 - Grumezescu, Alexandru Mihai. In Fabrication and Self-Assembly of Nanobiomaterials (Ed.^(Eds  pp. 459-483. (William Andrew Publishing). //www.sciencedirect.com/science/article/pii/B9780323415330000155

Sidhu AK, Sussman S, Tewari A, Bassi S and Arora M (2016) Project EX-India: A classroom-based tobacco use prevention and cessation intervention program. Addictive Behaviors 53, 53-57. //www.sciencedirect.com/science/article/pii/S0306460315300162

Vasantha-Srinivasan P, Senthil-Nathan S, et al. (2016) Developmental response of Spodoptera litura Fab. to treatments of crude volatile oil from Piper betle L. and evaluation of toxicity to earthworm, Eudrilus eugeniae Kinb. Chemosphere 155, 336-347. //www.sciencedirect.com/science/article/pii/S0045653516304635

Venkadeswaran K, Thomas PA and Geraldine P (2016) An experimental evaluation of the anti-atherogenic potential of the plant, Piper betle, and its active constitutent, eugenol, in rats fed an atherogenic diet. Biomedicine & Pharmacotherapy 80, 276-288. //www.sciencedirect.com/science/article/pii/S075333221530353X

Yip J and Luk MYA (2016) 3 - Microencapsulation technologies for antimicrobial textiles A2 - Sun, Gang. In Antimicrobial Textiles (Ed.^(Eds  pp. 19-46. (Woodhead Publishing). //www.sciencedirect.com/science/article/pii/B9780081005767000031

Desclos-Théveniau M, Coquet L, Jouenne T and Etienne P (2015) Proteomic analysis of residual proteins in blades and petioles of fallen leaves of Brassica napus. Plant Biology 17, 408-418. http://dx.doi.org/10.1111/plb.12241

Ho M-C, Li R-H and Tang T-C (2015) Betel nut chewing effects on sustained attention and inhibitory control after sleep deprivation. Australian Journal of Psychology 67, 222-230. http://dx.doi.org/10.1111/ajpy.12081

Kichu M, Malewska T, Akter K, Imchen I, Harrington D, Kohen J, Vemulpad SR and Jamie JF (2015) An ethnobotanical study of medicinal plants of Chungtia village, Nagaland, India. Journal of Ethnopharmacology 166, 5-17. //www.sciencedirect.com/science/article/pii/S0378874115001415

Kumar S, Pathania AS, Satti NK, Dutt P, Sharma N, Mallik FA and Ali A (2015) Synthetic modification of hydroxychavicol by Mannich reaction and alkyne–azide cycloaddition derivatives depicting cytotoxic potential. European Journal of Medicinal Chemistry 92, 236-245. //www.sciencedirect.com/science/article/pii/S0223523414011568

Kuppusamy S, Thavamani P, Megharaj M and Naidu R (2015) Bioremediation potential of natural polyphenol rich green wastes: A review of current research and recommendations for future directions. Environmental Technology & Innovation 4, 17-28. //www.sciencedirect.com/science/article/pii/S2352186415000139

Li W-C, Lee P-L, Chou IC, Chang W-J, Lin S-C and Chang K-W (2015) Molecular and cellular cues of diet-associated oral carcinogenesis—with an emphasis on areca-nut-induced oral cancer development. Journal of Oral Pathology & Medicine 44, 167-177. http://dx.doi.org/10.1111/jop.12171

Madathil SA, Rousseau M-C, et al. (2015) Maternal and paternal contribution to intergenerational psychosocial transmission of paan chewing. Community Dentistry and Oral Epidemiology 43, 289-297. http://dx.doi.org/10.1111/cdoe.12153

Mandal SC, Mandal V and Das AK (2015) Chapter 2 - History and Background on the Use of Natural Products Obtained from Plants as Therapeutic Agents. In Essentials of Botanical Extraction (Ed.^(Eds  pp. 7-17. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128023259000021

Mandal SC, Mandal V and Das AK (2015) Chapter 3 - Botanicals as a Screening Source of New Drugs: Past Success Stories and Present-Day Concerns. In Essentials of Botanical Extraction (Ed.^(Eds  pp. 19-33. (Academic Press: Boston). //www.sciencedirect.com/science/article/pii/B9780128023259000033

Mukherjee PK, Bahadur S, Chaudhary SK, Harwansh RK and Nema NK (2015) Chapter 5 - Validation of Medicinal Herbs for Skin Aging. In Evidence-Based Validation of Herbal Medicine (Ed.^(Eds  pp. 119-147. (Elsevier: Boston). //www.sciencedirect.com/science/article/pii/B9780128008744000052

Mukherjee PK, Bahadur S, Chaudhary SK, Kar A and Mukherjee K (2015) Chapter 1 - Quality Related Safety Issue-Evidence-Based Validation of Herbal Medicine Farm to Pharma. In Evidence-Based Validation of Herbal Medicine (Ed.^(Eds  pp. 1-28. (Elsevier: Boston). //www.sciencedirect.com/science/article/pii/B9780128008744000015

Prescott TAK, Briggs M, Kiapranis R and Simmonds MSJ (2015) Medicinal plants of Papua New Guineas Miu speaking population and a focus on their use of plant–slaked lime mixtures. Journal of Ethnopharmacology 174, 217-223. //www.sciencedirect.com/science/article/pii/S0378874115300854

Sarker SD and Nahar L (2015) Chapter 19 - Applications of High Performance Liquid Chromatography in the Analysis of Herbal Products A2 - Mukherjee, Pulok K. In Evidence-Based Validation of Herbal Medicine (Ed.^(Eds  pp. 405-425. (Elsevier: Boston). //www.sciencedirect.com/science/article/pii/B9780128008744000192

Shori AB (2015) Screening of antidiabetic and antioxidant activities of medicinal plants. Journal of Integrative Medicine 13, 297-305. //www.sciencedirect.com/science/article/pii/S2095496415601935

Swamy MK, Akhtar MS, Mohanty SK and Sinniah UR (2015) Synthesis and characterization of silver nanoparticles using fruit extract of Momordica cymbalaria and assessment of their in vitro antimicrobial, antioxidant and cytotoxicity activities. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 151, 939-944. //www.sciencedirect.com/science/article/pii/S1386142515300615

Vengaiah V, Govardhan Naik A and Changamma C (2015) Effect of Piper betel leaf stalk extract on protein metabolism in reproductive tissues of male albino rats. Asian Pacific Journal of Reproduction 4, 91-95. //www.sciencedirect.com/science/article/pii/S2305050015300026

Vuong QV, Nguyen VT, Thanh DT, Bhuyan DJ, Goldsmith CD, Sadeqzadeh E, Scarlett CJ and Bowyer MC (2015) Optimization of ultrasound-assisted extraction conditions for euphol from the medicinal plant, Euphorbia tirucalli, using response surface methodology. Industrial Crops and Products 63, 197-202. //www.sciencedirect.com/science/article/pii/S0926669014006025

Amari NO, Bouzouina M, Berkani A and Lotmani B (2014) Phytochemical screening and antioxidant capacity of the aerial parts of Thymelaea hirsuta L. Asian Pacific Journal of Tropical Disease 4, 104-109. //www.sciencedirect.com/science/article/pii/S2222180814603248

Bigoniya P and Singh K (2014) Ulcer protective potential of standardized hesperidin, a citrus flavonoid isolated from Citrus sinensis. Revista Brasileira de Farmacognosia 24, 330-340. //www.sciencedirect.com/science/article/pii/S0102695X14000350

Chellappandian M, Pandikumar P, Mutheeswaran S, Gabriel Paulraj M, Prabakaran S, Duraipandiyan V, Ignacimuthu S and Al-Dhabi NA (2014) Documentation and quantitative analysis of local ethnozoological knowledge among traditional healers of Theni district, Tamil Nadu, India. Journal of Ethnopharmacology 154, 116-130. //www.sciencedirect.com/science/article/pii/S0378874114002189

Chen F, Li F, Lu L, Zhang X, Xu X and Li D (2014) Phenolic profile and changes in the antioxidant activity of crabapple (Malus domestica cv Royalty) fruit during maturation on the tree. International Journal of Food Science & Technology 49, 1680-1688. http://dx.doi.org/10.1111/ijfs.12474

Cheng F (2014) Hydroxychavicol. In Handbook of Metabolic Pathways of Xenobiotics (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118541203.xen415

Das S (2014) Effect of antioxidants and nutrients in patients with allergy and asthma. Journal of Allergy and Clinical Immunology 134, 763. //www.sciencedirect.com/science/article/pii/S0091674914008604

Ferreres F, Oliveira AP, Gil-Izquierdo A, Valentão P and Andrade PB (2014) Piper betle Leaves: Profiling Phenolic Compounds by HPLC/DAD–ESI/MSn and Anti-cholinesterase Activity. Phytochemical Analysis 25, 453-460. http://dx.doi.org/10.1002/pca.2515

Ghate R, Patil VP, Hugar S, Matha NH and Kalyane NV (2014) Antihyperglycemic activity of Areca Catechu flowers. Asian Pacific Journal of Tropical Disease 4, Supplement 1, S148-S152. //www.sciencedirect.com/science/article/pii/S2222180814604308

Guha N, Warnakulasuriya S, Vlaanderen J and Straif K (2014) Betel quid chewing and the risk of oral and oropharyngeal cancers: A meta-analysis with implications for cancer control. International Journal of Cancer 135, 1433-1443. http://dx.doi.org/10.1002/ijc.28643

Gundala SR, Yang C, Mukkavilli R, Paranjpe R, Brahmbhatt M, Pannu V, Cheng A, Reid MD and Aneja R (2014) Hydroxychavicol, a betel leaf component, inhibits prostate cancer through ROS-driven DNA damage and apoptosis. Toxicology and Applied Pharmacology 280, 86-96. //www.sciencedirect.com/science/article/pii/S0041008X14002713

Herzog TA, Murphy KL, Little MA, Suguitan GS, Pokhrel P and Kawamoto CT (2014) The Betel Quid Dependence Scale: Replication and extension in a Guamanian sample. Drug and Alcohol Dependence 138, 154-160. //www.sciencedirect.com/science/article/pii/S0376871614000775

Hsu W-L, Chien Y-C, et al. (2014) Lifetime risk of distinct upper aerodigestive tract cancers and consumption of alcohol, betel and cigarette. International Journal of Cancer 135, 1480-1486. http://dx.doi.org/10.1002/ijc.28791

Jain S, Kumar S, Dohre S, Afley P, Sengupta N and Alam SI (2014) Identification of a protective protein from stationary-phase exoproteome of Brucella abortus. Pathogens and Disease 70, 75-83. http://dx.doi.org/10.1111/2049-632X.12079

Janel N and Noll C (2014) Chapter 51 - Protection and Reversal of Hepatic Fibrosis by Polyphenols. In Polyphenols in Human Health and Disease (Ed.^(Eds  pp. 665-679. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780123984562000517

McClintock TR, Parvez F, et al. (2014) Association between betel quid chewing and carotid intima-media thickness in rural Bangladesh. Int. J. Epidemiol. 43, 1174-1182. http://ije.oxfordjournals.org/cgi/content/abstract/43/4/1174

Molehin OR, Adefegha SA, Oboh G, Saliu JA, Athayde ML and Boligon AA (2014) Comparative Study on the Phenolic Content, Antioxidant Properties and HPLC Fingerprinting of Three Varieties of Celosia Species. Journal of Food Biochemistry 38, 575-583. http://dx.doi.org/10.1111/jfbc.12090

Nigam NK, Aravinda K, Dhillon M, Gupta S, Reddy S and Srinivas Raju M (2014) Prevalence of oral submucous fibrosis among habitual gutkha and areca nut chewers in Moradabad district. Journal of Oral Biology and Craniofacial Research 4, 8-13. //www.sciencedirect.com/science/article/pii/S2212426813000857

Nouri L and Mohammadi Nafchi A (2014) Antibacterial, mechanical, and barrier properties of sago starch film incorporated with betel leaves extract. International Journal of Biological Macromolecules 66, 254-259. //www.sciencedirect.com/science/article/pii/S0141813014001287

Nouri L, Mohammadi Nafchi A and Karim AA (2014) Phytochemical, antioxidant, antibacterial, and α-amylase inhibitory properties of different extracts from betel leaves. Industrial Crops and Products 62, 47-52. //www.sciencedirect.com/science/article/pii/S0926669014004956

Patacsil M, Manuel J, Laruan LMVA, Cortez SM and Balangcod TD (2014) Phytochemical and antimicrobial studies of selected aromatic plants in the Philippines. Acta horticulturae., 143-148. http://www.actahort.org/books/1023/1023_20.htm

Raut JS and Karuppayil SM (2014) A status review on the medicinal properties of essential oils. Industrial Crops and Products 62, 250-264. //www.sciencedirect.com/science/article/pii/S0926669014005196

Thirumalai T, Tamilselvan N and David E (2014) Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat. Journal of Acute Disease 3, 131-135. //www.sciencedirect.com/science/article/pii/S2221618914600299

Wijenayake A, Pitawala A, Bandara R and Abayasekara C (2014) The role of herbometallic preparations in traditional medicine – A review on mica drug processing and pharmaceutical applications. Journal of Ethnopharmacology 155, 1001-1010. //www.sciencedirect.com/science/article/pii/S0378874114004991

Yadav Y, Owens EA, Sharma V, Aneja R and Henary M (2014) Synthesis and evaluation of antiproliferative activity of a novel series of hydroxychavicol analogs. European Journal of Medicinal Chemistry 75, 1-10. //www.sciencedirect.com/science/article/pii/S0223523414000476

Zaman MJ (2014) Commentary: No smoke without firethe continuing menace of the betel nut in the worlds most vulnerable populations. Int. J. Epidemiol. 43, 1183-1186. http://ije.oxfordjournals.org

Ahmed S, Ahsan KB, et al. (2013) Table_of_Contents

In Utero Arsenic Exposure Is Associated With Impaired Thymic Function in Newborns Possibly Via Oxidative Stress and Apoptosis. Carcinogenesis 34, NP-e-. http://carcin.oxfordjournals.org http://toxsci.oxfordjournals.org/cgi/content/abstract/129/2/305

Ajanal M, Nayak S, Prasad BS and Kadam A (2013) Adverse drug reaction and concepts of drug safety in Ayurveda: An overview. Journal of Young Pharmacists 5, 116-120. //www.sciencedirect.com/science/article/pii/S0975148313000423

Baliga MS, Fazal F, Rashmi Priya M, Ratnu VS and Rai MP (2013) Chapter 43 - Betel Leaf (.0Piper betel Linn): The Wrongly Maligned Medicinal and Recreational Plant Possesses Potent Gastrointestinal and Hepatoprotective Effects A2 - Watson, Ronald Ross. In Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease (Ed.^(Eds Preedy VR) pp. 673-684. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B978012397154800035X

Ganguly A, Mahmud ZA, Uddin MMN and Rahman SMA (2013) In-vivo anti-inflammatory and anti-pyretic activities of Manilkara zapota leaves in albino Wistar rats. Asian Pacific Journal of Tropical Disease 3, 301-307. //www.sciencedirect.com/science/article/pii/S2222180813600730

Gardner RM, Kippler M, et al. (2013) Environmental Exposure to Metals and Childrens Growth to Age 5 Years: A Prospective Cohort Study. Am. J. Epidemiol. 177, 1356-1367. http://aje.oxfordjournals.org/cgi/content/abstract/177/12/1356

Gardner RM, Kippler M, et al. (2013) Table_of_Contents

Environmental Exposure to Metals and Childrens Growth to Age 5 Years: A Prospective Cohort Study. Carcinogenesis 34, NP-e-. http://carcin.oxfordjournals.org http://aje.oxfordjournals.org/cgi/content/abstract/177/12/1356

Gupta B, Ariyawardana A and Johnson NW (2013) Oral cancer in India continues in epidemic proportions: evidence base and policy initiatives. International Dental Journal 63, 12-25. http://dx.doi.org/10.1111/j.1875-595x.2012.00131.x

Hardon A, Idrus NI and Hymans TD (2013) Chemical sexualities: the use of pharmaceutical and cosmetic products by youth in South Sulawesi, Indonesia. Reproductive Health Matters 21, 214-224. //www.sciencedirect.com/science/article/pii/S0968808013417093

Khan AA, Bhatnagar SP, Sinha BN and Lal UR (2013) Pharmacognostic specifications of eight cultivars of Piper betle from eastern region of India. Pharmacognosy Journal 5, 176-183. //www.sciencedirect.com/science/article/pii/S0975357513000461

Kumar D, Ghosh R and Pal BC (2013) α-Glucosidase inhibitory terpenoids from Potentilla fulgens and their quantitative estimation by validated HPLC method. Journal of Functional Foods 5, 1135-1141. //www.sciencedirect.com/science/article/pii/S1756464613000790

Kumari S and Dutta A (2013) Protective effect of Eleteria cardamomum (L.) Maton against Pan masala induced damage in lung of male Swiss mice. Asian Pacific Journal of Tropical Medicine 6, 525-531. //www.sciencedirect.com/science/article/pii/S1995764513600905

Laloo D, Kumar M, Prasad SK and Hemalatha S (2013) Quality control standardization of the roots of Potentilla fulgens Wall.: A potent medicinal plant of the Western Himalayas and North-eastern India. Pharmacognosy Journal 5, 97-103. //www.sciencedirect.com/science/article/pii/S0975357513000266

Ma G-C, Wu P-F, Tseng H-C, Chyau C-C, Lu H-C and Chou F-P (2013) Inhibitory effect of Piper betel leaf extracts on copper-mediated LDL oxidation and oxLDL-induced lipid accumulation via inducing reverse cholesterol transport in macrophages. Food Chemistry 141, 3703-3713. //www.sciencedirect.com/science/article/pii/S0308814613007632

Paranjpe R, Gundala SR, Lakshminarayana N, Sagwal A, Asif G, Pandey A and Aneja R (2013) Piper betel leaf extract: anticancer benefits and bio-guided fractionation to identify active principles for prostate cancer management. Carcinogenesis 34, 1558-1566. http://carcin.oxfordjournals.org/cgi/content/abstract/34/7/1558

Sarkar D, Kundu S, De S, Hariharan C, Saha P, Manna A, Chattopadhyay S and Chatterjee M (2013) The Antioxidant Activity of Allylpyrocatechol is Mediated via Decreased Generation of Free Radicals Along With Escalation of Antioxidant Mechanisms. Phytotherapy Research 27, 324-329. http://dx.doi.org/10.1002/ptr.4720

Sathya A and Siddhuraju P (2013) Effect of Indigenous Processing Methods on Phenolics and Antioxidant Potential of Underutilized Legumes Acacia auriculiformis and Parkia roxburghii. Journal of Food Quality 36, 98-112. http://dx.doi.org/10.1111/jfq.12024

Uno T, Obe Y, Ogura C, Goto T, Yamamoto K, Nakamura M, Kanamaru K, Yamagata H and Imaishi H (2013) Metabolism of 7-ethoxycoumarin, safrole, flavanone and hydroxyflavanone by cytochrome P450 2A6 variants. Biopharmaceutics & Drug Disposition 34, 87-97. http://dx.doi.org/10.1002/bdd.1825

Winstock AR (2013) Chapter 87 - Areca Nut, Betel Quids, and Associated Products A2 - Miller, Peter M. In Principles of Addiction (Ed.^(Eds  pp. 863-872. (Academic Press: San Diego). //www.sciencedirect.com/science/article/pii/B9780123983367000875

Adate PS, Parmesawaran S and Chauhan Y (2012) In vitro Anthelmintic Activity of Stem Extracts of Piper betle Linn Against Pheritima Posthuma. Pharmacognosy Journal 4, 61-65. //www.sciencedirect.com/science/article/pii/S0975357512800563

Adnan N and Othman N (2012) The Relationship between Plants and the Malay Culture. Procedia - Social and Behavioral Sciences 42, 231-241. http://www.sciencedirect.com/science/article/pii/S1877042812010683

Ahmed S, Ahsan KB, et al. (2012) In Utero Arsenic Exposure Is Associated With Impaired Thymic Function in Newborns Possibly Via Oxidative Stress and Apoptosis. Toxicol. Sci. 129, 305-314. http://toxsci.oxfordjournals.org/cgi/content/abstract/129/2/305

Almeida LO, Goto RN, Pestana CR, Uyemura SA, Gutkind S, Curti C and Leopoldino AM (2012) SET overexpression decreases cell detoxification efficiency: ALDH2 and GSTP1 are downregulated, DDR is impaired and DNA damage accumulates. FEBS Journal 279, 4615-4628. http://dx.doi.org/10.1111/febs.12047

Bothara SB and Singh S (2012) Pharmacognostical Studies of Seeds on Some Plants Belonging Chhattisgarh. Pharmacognosy Journal 4, 24-30. //www.sciencedirect.com/science/article/pii/S097535751280071X

Chandel M, Sharma U, Kumar N, Singh B and Kaur S (2012) Antioxidant activity and identification of bioactive compounds from leaves of Anthocephalus cadamba by ultra–performance liquid chromatography/electrospray ionization quadrupole time of flight mass spectrometry. Asian Pacific Journal of Tropical Medicine 5, 977-985. //www.sciencedirect.com/science/article/pii/S1995764512601862

Chellappandian M, Mutheeswaran S, Pandikumar P, Duraipandiyan V and Ignacimuthu S (2012) Quantitative ethnobotany of traditional Siddha medical practitioners from Radhapuram taluk of Tirunelveli District, Tamil Nadu, India. Journal of Ethnopharmacology 143, 540-547. //www.sciencedirect.com/science/article/pii/S0378874112004837

Chen P-H, Tu H-P, et al. (2012) Monoamine oxidase A variants are associated with heavy betel quid use. Addiction Biology 17, 786-797. http://dx.doi.org/10.1111/j.1369-1600.2011.00331.x

Chue AL, Carrara VI, Paw MK, Pimanpanarak M, Wiladphaingern J, van Vugt M, Lee SJ, Nosten F and McGready R (2012) Is areca innocent? The effect of areca (betel) nut chewing in a population of pregnant women on the Thai-Myanmar border. Int. Health 4, 204-209. http://inthealth.oxfordjournals.org/cgi/content/abstract/4/3/204

Chue AL, Carrara VI, Paw MK, Pimanpanarak M, Wiladphaingern J, van Vugt M, Lee SJ, Nosten F and McGready R (2012) Is areca innocent? The effect of areca (betel) nut chewing in a population of pregnant women on the Thai–Myanmar border. International Health 4, 204-209. //www.sciencedirect.com/science/article/pii/S187634131200040X

Jain S, Jain DK and Balekar N (2012) In–Vivo Antioxidant activity of ethanolic extract of Mentha pulegium leaf against CCl4 induced toxicity in rats. Asian Pacific Journal of Tropical Biomedicine 2, S737-S740. //www.sciencedirect.com/science/article/pii/S2221169112603062

Khan Z, Bashir O, Hussain J, Kumar S and Ahmad R (2012) Effects of ionic surfactants on the morphology of silver nanoparticles using Paan (Piper betel) leaf petiole extract. Colloids Surf B Biointerfaces 98, 85-90.

Khan Z, Bashir O, Hussain JI, Kumar S and Ahmad R (2012) Effects of ionic surfactants on the morphology of silver nanoparticles using Paan (Piper betel) leaf petiole extract. Colloids and Surfaces B: Biointerfaces 98, 85-90. http://www.sciencedirect.com/science/article/pii/S0927776512002524

Khan Z, Bashir O, Hussain JI, Kumar S and Ahmad R (2012) Effects of ionic surfactants on the morphology of silver nanoparticles using Paan (Piper betel) leaf petiole extract. Colloids and surfaces. 1, 98. http://dx.doi.org/10.1016/j.colsurfb.2012.04.033

Kumar A, Kumar V, Singh J, Hooda A and Dutta S (2012) Drug-Induced Discoloration of Teeth: An Updated Review. Clinical Pediatrics 51, 181-185. http://cpj.sagepub.com/cgi/content/abstract/51/2/181

Lee C-H, Lee K-W, et al. (2012) The neoplastic impact of tobacco-free betel-quid on the histological type and the anatomical site of aerodigestive tract cancers. International Journal of Cancer 131, E733-E743. http://dx.doi.org/10.1002/ijc.27401

Lee C-Y, Chang C-S, Shieh T-Y and Chang Y-Y (2012) Development and validation of a self-rating scale for betel quid chewers based on a male-prisoner population in Taiwan: The Betel Quid Dependence Scale. Drug and Alcohol Dependence 121, 18-22. http://www.sciencedirect.com/science/article/pii/S0376871611003772

Maity N, Nema N, Sellamuthu M, Sarkar B and Mukherjee P (2012) Simultaneous estimation of hydroxychavicol and chlorogenic acid from Piper betel L. through RP-HPLC. Nat Prod Res 26, 1939-41.

Maity N, Nema NK, Sellamuthu MK, Sarkar BK and Mukherjee PK (2012) Simultaneous estimation of hydroxychavicol and chlorogenic acid from Piper betel L. through RP-HPLC. Natural product research. 26, 1939-1941. http://dx.doi.org/10.1080/14786419.2011.619189

Milton Prabu S, Muthumani M and Shagirtha K (2012) Protective effect of Piper betle leaf extract against cadmium-induced oxidative stress and hepatic dysfunction in rats. Saudi Journal of Biological Sciences 19, 229-239. http://www.sciencedirect.com/science/article/pii/S1319562X1200006X

Mondal S, Das D, Roy SK and Islam SS (2012) Isolation, purification and structural characterization of an acetylated heteroglycan from the unripe fruits of Manilkara zapota L. Carbohydrate Research 354, 74-78. http://www.sciencedirect.com/science/article/pii/S0008621512000754

Nagani K, Kaneria M and Chanda S (2012) Pharmacognostic studies on the leaves of Manilkara zapota L. (Sapotaceae). Pharmacognosy Journal 4, 38-41. //www.sciencedirect.com/science/article/pii/S0975357512800198

Nema NK, Maity N, Sarkar BK and Mukherjee PK (2012) Determination of trace and heavy metals in some commonly used medicinal herbs in Ayurveda. Toxicology and Industrial Health, 0748233712468015. http://tih.sagepub.com/cgi/content/abstract/0748233712468015v1

Nithiyanantham S, Selvakumar S and Siddhuraju P (2012) Total phenolic content and antioxidant activity of two different solvent extracts from raw and processed legumes, Cicer arietinum L. and Pisum sativum L. Journal of Food Composition and Analysis 27, 52-60. http://www.sciencedirect.com/science/article/pii/S0889157512000749

Prescott TAK, Kiapranis R and Maciver SK (2012) Comparative ethnobotany and in-the-field antibacterial testing of medicinal plants used by the Bulu and inland Kaulong of Papua New Guinea. Journal of Ethnopharmacology 139, 497-503. http://www.sciencedirect.com/science/article/pii/S0378874111008488

Rajakumar G and Abdul Rahuman A (2012) Acaricidal activity of aqueous extract and synthesized silver nanoparticles from Manilkara zapota against Rhipicephalus (Boophilus) microplus. Research in Veterinary Science 93, 303-309. http://www.sciencedirect.com/science/article/pii/S003452881100333X

Sarkar D, Kundu S, De S, Hariharan C, Saha P, Manna A, Chattopadhyay S and Chatterjee M (2012) The Antioxidant Activity of Allylpyrocatechol is Mediated via Decreased Generation of Free Radicals Along With Escalation of Antioxidant Mechanisms. Phytotherapy Research, n/a-n/a. http://dx.doi.org/10.1002/ptr.4720

Sathya A and Siddhuraju P (2012) Role of phenolics as antioxidants, biomolecule protectors and as anti–diabetic factors – Evaluation on bark and empty pods of Acacia auriculiformis. Asian Pacific Journal of Tropical Medicine 5, 757-765. //www.sciencedirect.com/science/article/pii/S1995764512601394

Sharma A, Kaithwas G, Vijayakumar M, Unnikrishnan MK and Rao CV (2012) ANTIHYPERGLYCEMIC AND ANTIOXIDANT POTENTIAL OF POLYSACCHARIDE FRACTION FROM PORTULACA OLERACEA SEEDS AGAINST STREPTOZOTOCIN-INDUCED DIABETES IN RATS. Journal of Food Biochemistry 36, 378-382. http://dx.doi.org/10.1111/j.1745-4514.2011.00547.x

Sharma J, Gairola S, Gaur RD and Painuli RM (2012) The treatment of jaundice with medicinal plants in indigenous communities of the Sub-Himalayan region of Uttarakhand, India. Journal of Ethnopharmacology 143, 262-291. //www.sciencedirect.com/science/article/pii/S0378874112004345

Shen L-C, Chiang S-Y, Lin M-H, Chung W-S and Wu K-Y (2012) In vivo formation of N7-guanine DNA adduct by safrole 2′,3′-oxide in mice. Toxicology Letters 213, 309-315. //www.sciencedirect.com/science/article/pii/S037842741201212X

Singh K, Singh N, Chandy A and Manigauha A (2012) In vivo antioxidant and hepatoprotective activity of methanolic extracts of Daucus carota seeds in experimental animals. Asian Pacific Journal of Tropical Biomedicine 2, 385-388. http://www.sciencedirect.com/science/article/pii/S2221169112600616

Weng CJ, Hsieh YH, Chen MK, Tsai CM, Lin CW and Yang SF (2012) Survivin SNP-carcinogen Interactions in Oral Cancer. Journal of Dental Research 91, 358-363. http://jdr.sagepub.com/cgi/content/abstract/91/4/358

Zhu L, Huang B, Ban X, He J, Chen Y, Han L and Wang Y (2012) Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition. Food and Chemical Toxicology 50, 2584-2588. http://www.sciencedirect.com/science/article/pii/S0278691512003195

 

 

References 1901-2013 (and links to abstracts):
[Number of papers mentioning Piper betel: 346; Any undated papers have been included at the end]

 

Ahmed S, Ahsan KB, et al. (2013) Table_of_Contents

In Utero Arsenic Exposure Is Associated With Impaired Thymic Function in Newborns Possibly Via Oxidative Stress and Apoptosis. Carcinogenesis 34, NP-e-. http://carcin.oxfordjournals.org http://toxsci.oxfordjournals.org/cgi/content/abstract/129/2/305

Gardner RM, Kippler M, et al. (2013) Environmental Exposure to Metals and Children’s Growth to Age 5 Years: A Prospective Cohort Study. Am. J. Epidemiol. 177, 1356-67. http://aje.oxfordjournals.org/cgi/content/abstract/177/12/1356

Paranjpe R, Gundala SR, Lakshminarayana N, Sagwal A, Asif G, Pandey A, Aneja R (2013) Piper betel leaf extract: anticancer benefits and bio-guided fractionation to identify active principles for prostate cancer management. Carcinogenesis 34, 1558-66. http://carcin.oxfordjournals.org/cgi/content/abstract/34/7/1558

Adnan N, Othman N (2012) The Relationship between Plants and the Malay Culture. Procedia - Social and Behavioral Sciences 42, 231-41. http://www.sciencedirect.com/science/article/pii/S1877042812010683

Al-Rmalli SW, Jenkins RO, Haris PI (2012) Dietary Intake of Cadmium from Bangladeshi Foods. Journal of Food Science 77, T26-T33. http://dx.doi.org/10.1111/j.1750-3841.2011.02467.x

Barceloux DG (2012) Betel Quid and Areca Nut. In ‘Medical Toxicology of Drug Abuse’ pp. 781-7. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118105955.ch54

Chakraborty JB, Mahato SK, et al. (2012) Hydroxychavicol, a Piper betle leaf component, induces apoptosis of CML cells through mitochondrial reactive oxygen species-dependent JNK and endothelial nitric oxide synthase activation and overrides imatinib resistance. Cancer Science 103, 88-99. http://dx.doi.org/10.1111/j.1349-7006.2011.02107.x

Chen P-H, Tu H-P, et al. (2012) Monoamine oxidase A variants are associated with heavy betel quid use. Addiction Biology 17, 786-97. http://dx.doi.org/10.1111/j.1369-1600.2011.00331.x

Chien M-H, Chou LS-S, Chung T-T, Lin C-H, Chou M-Y, Weng M-S, Yang S-F, Chen M-K (2012) Effects of E-cadherin (CDH1) gene promoter polymorphisms on the risk and clinicopathologic development of oral cancer. Head & Neck 34, 405-11. http://dx.doi.org/10.1002/hed.21746

Chue AL, Carrara VI, Paw MK, Pimanpanarak M, Wiladphaingern J, van Vugt M, Lee SJ, Nosten F, McGready R (2012) Is areca innocent? The effect of areca (betel) nut chewing in a population of pregnant women on the Thai-Myanmar border. Int. Health 4, 204-9. http://inthealth.oxfordjournals.org/cgi/content/abstract/4/3/204

Khan Z, Bashir O, Hussain J, Kumar S, Ahmad R (2012) Effects of ionic surfactants on the morphology of silver nanoparticles using Paan (Piper betel) leaf petiole extract. Colloids Surf B Biointerfaces 98, 85-90.

Khan Z, Bashir O, Hussain JI, Kumar S, Ahmad R (2012) Effects of ionic surfactants on the morphology of silver nanoparticles using Paan (Piper betel) leaf petiole extract. Colloids and Surfaces B: Biointerfaces 98, 85-90. http://www.sciencedirect.com/science/article/pii/S0927776512002524

Kumar A, Kumar V, Singh J, Hooda A, Dutta S (2012) Drug-Induced Discoloration of Teeth: An Updated Review. Clinical Pediatrics 51, 181-5. http://cpj.sagepub.com/cgi/content/abstract/51/2/181

Lee C-H, Lee K-W, et al. (2012) The neoplastic impact of tobacco-free betel-quid on the histological type and the anatomical site of aerodigestive tract cancers. International Journal of Cancer 131, E733-E43. http://dx.doi.org/10.1002/ijc.27401

Lee C-Y, Chang C-S, Shieh T-Y, Chang Y-Y (2012) Development and validation of a self-rating scale for betel quid chewers based on a male-prisoner population in Taiwan: The Betel Quid Dependence Scale. Drug and Alcohol Dependence 121, 18-22. http://www.sciencedirect.com/science/article/pii/S0376871611003772

Liu CM, Yeh CJ, Yu CC, Chou MY, Lin CH, Wei LH, Lin CW, Yang SF, Chien MH (2012) Impact of interleukin-8 gene polymorphisms and environmental factors on oral cancer susceptibility in Taiwan. Oral Diseases 18, 307-14. http://dx.doi.org/10.1111/j.1601-0825.2011.01882.x

Maity N, Nema N, Sellamuthu M, Sarkar B, Mukherjee P (2012) Simultaneous estimation of hydroxychavicol and chlorogenic acid from Piper betel L. through RP-HPLC. Nat Prod Res 26, 1939-41.

Milton Prabu S, Muthumani M, Shagirtha K (2012) Protective effect of Piper betle leaf extract against cadmium-induced oxidative stress and hepatic dysfunction in rats. Saudi Journal of Biological Sciences 19, 229-39. http://www.sciencedirect.com/science/article/pii/S1319562X1200006X

Mondal S, Das D, Roy SK, Islam SS (2012) Isolation, purification and structural characterization of an acetylated heteroglycan from the unripe fruits of Manilkara zapota L. Carbohydrate Research 354, 74-8. http://www.sciencedirect.com/science/article/pii/S0008621512000754

Nema NK, Maity N, Sarkar BK, Mukherjee PK (2012) Determination of trace and heavy metals in some commonly used medicinal herbs in Ayurveda. Toxicology and Industrial Health, 0748233712468015. http://tih.sagepub.com/cgi/content/abstract/0748233712468015v1

Nithiyanantham S, Selvakumar S, Siddhuraju P (2012) Total phenolic content and antioxidant activity of two different solvent extracts from raw and processed legumes, Cicer arietinum L. and Pisum sativum L. Journal of Food Composition and Analysis 27, 52-60. http://www.sciencedirect.com/science/article/pii/S0889157512000749

Prescott TAK, Kiapranis R, Maciver SK (2012) Comparative ethnobotany and in-the-field antibacterial testing of medicinal plants used by the Bulu and inland Kaulong of Papua New Guinea. Journal of Ethnopharmacology 139, 497-503. http://www.sciencedirect.com/science/article/pii/S0378874111008488

Rajakumar G, Abdul Rahuman A (2012) Acaricidal activity of aqueous extract and synthesized silver nanoparticles from Manilkara zapota against Rhipicephalus (Boophilus) microplus. Research in Veterinary Science 93, 303-9. http://www.sciencedirect.com/science/article/pii/S003452881100333X

Sarkar D, Kundu S, De S, Hariharan C, Saha P, Manna A, Chattopadhyay S, Chatterjee M (2012) The Antioxidant Activity of Allylpyrocatechol is Mediated via Decreased Generation of Free Radicals Along With Escalation of Antioxidant Mechanisms. Phytotherapy Research, n/a-n/a. http://dx.doi.org/10.1002/ptr.4720

Sharma A, Kaithwas G, Vijayakumar M, Unnikrishnan MK, Rao CV (2012) ANTIHYPERGLYCEMIC AND ANTIOXIDANT POTENTIAL OF POLYSACCHARIDE FRACTION FROM PORTULACA OLERACEA SEEDS AGAINST STREPTOZOTOCIN-INDUCED DIABETES IN RATS. Journal of Food Biochemistry 36, 378-82. http://dx.doi.org/10.1111/j.1745-4514.2011.00547.x

Sharma J, Ponnusamy Pazhaniandi P, Tanwar VK, Das SK, Goswami M (2012) Antioxidant effect of turmeric powder, nitrite and ascorbic acid on stored chicken mince. International Journal of Food Science & Technology 47, 61-6. http://dx.doi.org/10.1111/j.1365-2621.2011.02807.x

Singh K, Singh N, Chandy A, Manigauha A (2012) In vivo antioxidant and hepatoprotective activity of methanolic extracts of Daucus carota seeds in experimental animals. Asian Pacific Journal of Tropical Biomedicine 2, 385-8. http://www.sciencedirect.com/science/article/pii/S2221169112600616

Vachiramon V, Thadanipon K, Rattanakaemakorn P (2012) Adult-onset dyschromatoses. Clinical and Experimental Dermatology 37, 97-103. http://dx.doi.org/10.1111/j.1365-2230.2011.04161.x

Weng CJ, Hsieh YH, Chen MK, Tsai CM, Lin CW, Yang SF (2012) Survivin SNP-carcinogen Interactions in Oral Cancer. Journal of Dental Research 91, 358-63. http://jdr.sagepub.com/cgi/content/abstract/91/4/358

Zhu L, Huang B, Ban X, He J, Chen Y, Han L, Wang Y (2012) Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition. Food and Chemical Toxicology 50, 2584-8. http://www.sciencedirect.com/science/article/pii/S0278691512003195

Anonymous (2011) Abstracts presented at the Australian and New Zealand Association of Clinical Anatomists (ANZACA) 7th Annual Meeting, “Anatomy educators: Making anatomy necessary and attractive to modern audiences” held in Hobart, Tasmania from 2nd to 3rd of December, 2010. Clinical Anatomy 24, 398-408. http://dx.doi.org/10.1002/ca.21157

Al-Rmalli S, Jenkins R, Haris P (2011) Betel quid chewing elevates human exposure to arsenic, cadmium and lead. J Hazard Mater 190, 69-74.

Al-Rmalli S, Jenkins R, Haris P (2011) Betel quid chewing as a source of manganese exposure: total daily intake of manganese in a Bangladeshi population. BMC Public Health 11, 85.

Al-Rmalli SW, Jenkins RO, Haris PI (2011) Betel quid chewing elevates human exposure to arsenic, cadmium and lead. Journal of Hazardous Materials 190, 69-74. http://www.sciencedirect.com/science/article/pii/S030438941100269X

Chen P-H, Lee K-W, et al. (2011) CYP26B1 is a novel candidate gene for betel quid-related oral squamous cell carcinoma. Oral Oncology 47, 594-600. http://www.sciencedirect.com/science/article/pii/S1368837511001643

Chiang S-y, Lee P-y, Lai M-t, Shen L-c, Chung W-s, Huang H-f, Wu K-y, Wu H-c (2011) Safrole-2′,3′-oxide induces cytotoxic and genotoxic effects in HepG2 cells and in mice. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 726, 234-41. http://www.sciencedirect.com/science/article/pii/S1383571811002798

Chung T-T, Pan M-S, Kuo C-L, Wong R-H, Lin C-W, Chen M-K, Yang S-F (2011) Impact of RECK gene polymorphisms and environmental factors on oral cancer susceptibility and clinicopathologic characteristics in Taiwan. Carcinogenesis 32, 1063-8. http://carcin.oxfordjournals.org/cgi/content/abstract/32/7/1063

Feng Y, Wang N, Ye X, Li H, Feng Y, Cheung F, Nagamatsu T (2011) Hepatoprotective effect and its possible mechanism of Coptidis rhizoma aqueous extract on carbon tetrachloride-induced chronic liver hepatotoxicity in rats. Journal of Ethnopharmacology 138, 683-90. http://www.sciencedirect.com/science/article/pii/S0378874111007021

Johnson NW, Jayasekara P, Amarasinghe AAHK (2011) Squamous cell carcinoma and precursor lesions of the oral cavity: epidemiology and aetiology. Periodontology 2000 57, 19-37. http://dx.doi.org/10.1111/j.1600-0757.2011.00401.x

Johnson NW, Warnakulasuriya S, Gupta PC, Dimba E, Chindia M, Otoh EC, Sankaranarayanan R, Califano J, Kowalski L (2011) Global Oral Health Inequalities in Incidence and Outcomes for Oral Cancer: Causes and Solutions. Advances in Dental Research 23, 237-46. http://adr.sagepub.com/cgi/content/abstract/23/2/237

Kader G, Nikkon F, Rashid MA, Yeasmin T (2011) Antimicrobial activities of the rhizome extract of Zingiber zerumbet Linn. Asian Pacific Journal of Tropical Biomedicine 1, 409-12. http://www.sciencedirect.com/science/article/pii/S2221169111600907

Lee C-H, Lee K-W, et al. (2011) The use of tobacco-free betel-quid in conjunction with alcohol/tobacco impacts early-onset age and carcinoma distribution for upper aerodigestive tract cancer. Journal of Oral Pathology & Medicine 40, 684-92. http://dx.doi.org/10.1111/j.1600-0714.2011.01022.x

Mukherjee PK, Maity N, Nema NK, Sarkar BK (2011) Bioactive compounds from natural resources against skin aging. Phytomedicine 19, 64-73. http://www.sciencedirect.com/science/article/pii/S0944711311005022

Osman MA, Rashid MM, Aziz MA, Habib MR, karim MR (2011) Inhibition of Ehrlich ascites carcinoma by Manilkara zapota L. stem bark in Swiss albino mice. Asian Pacific Journal of Tropical Biomedicine 1, 448-51. http://www.sciencedirect.com/science/article/pii/S2221169111600981

Rai M, Thilakchand K, Palatty P, Rao P, Rao S, Bhat H, Baliga M (2011) Piper betel Linn (betel vine), the maligned Southeast Asian medicinal plant possesses cancer preventive effects: time to reconsider the wronged opinion. Asian Pac J Cancer Prev 12, 2149-56.

Sahoo NG, Kakran M, Shaal LA, Li L, Müller RH, Pal M, Tan LP (2011) Preparation and characterization of quercetin nanocrystals. Journal of Pharmaceutical Sciences 100, 2379-90. http://dx.doi.org/10.1002/jps.22446

Saravanan G, Ponmurugan P (2011) Ameliorative potential of S-allyl cysteine on oxidative stress in STZ induced diabetic rats. Chemico-Biological Interactions 189, 100-6. http://www.sciencedirect.com/science/article/pii/S0009279710005806

Stanfill SB, Connolly GN, et al. (2011) Global surveillance of oral tobacco products: total nicotine, unionised nicotine and tobacco-specific N-nitrosamines. Tob. Control 20, e2-. http://tobaccocontrol.bmj.com/cgi/content/abstract/20/3/e2

Taur DJ, Patil RY (2011) Some medicinal plants with antiasthmatic potential: a current status. Asian Pacific Journal of Tropical Biomedicine 1, 413-8. http://www.sciencedirect.com/science/article/pii/S2221169111600919

Tirupathi RG, Suresh BK, Kumar JU, Sujana P, Rao AV, Sreedhar AS (2011) Anti–microbial principles of selected remedial plants from Southern India. Asian Pacific Journal of Tropical Biomedicine 1, 298-305. http://www.sciencedirect.com/science/article/pii/S2221169111600476

Chiu C, Chen B, et al. (2010) Betel quid extract promotes oral cancer cell migration by activating a muscarinic M4 receptor-mediated signaling cascade involving SFKs and ERK1/2. Biochem Biophys Res Commun 399, 60-5.

Chung C-S, Lee Y-C, Wang C-P, Ko J-Y, Wang W-L, Wu M-S, Wang H-P (2010) Secondary Prevention of Esophageal Squamous Cell Carcinoma in Areas Where Smoking, Alcohol, and Betel Quid Chewing are Prevalent. Journal of the Formosan Medical Association 109, 408-21. http://www.sciencedirect.com/science/article/pii/S0929664610600721

Feinberg R (2010) Marine resource conservation and prospects for environmental sustainability in Anuta, Solomon Islands. Singapore Journal of Tropical Geography 31, 41-54. http://dx.doi.org/10.1111/j.1467-9493.2010.00384.x

Huang S-H, Lee H-S, Mar K, Ji D-D, Huang M-S, Hsia K-T (2010) Loss expression of O6-methylguanine DNA methyltransferase by promoter hypermethylation and its relationship to betel quid chewing in oral squamous cell carcinoma. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 109, 883-9. http://www.sciencedirect.com/science/article/pii/S1079210409009366

Javed F, Bello Correra FO, Chotai M, Tappuni AR, Almas K (2010) Review Article: Systemic conditions associated with areca nut usage: A literature review. Scand J Public Health 38, 838-44. http://sjp.sagepub.com/cgi/content/abstract/38/8/838

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Khan Z, Bashir O, Hussain JI, Kumar S, Ahmad R Effects of ionic surfactants on the morphology of silver nanoparticles using Paan (Piper betel) leaf petiole extract. Colloids and Surfaces B: Biointerfaces 98, 85-90. http://www.sciencedirect.com/science/article/pii/S0927776512002524

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Lee C-Y, Chang C-S, Shieh T-Y, Chang Y-Y Development and validation of a self-rating scale for betel quid chewers based on a male-prisoner population in Taiwan: The Betel Quid Dependence Scale. Drug and Alcohol Dependence. http://www.sciencedirect.com/science/article/pii/S0376871611003772

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Milton Prabu S, Muthumani M, Shagirtha K Protective effect of Piper betle leaf extract against cadmium-induced oxidative stress and hepatic dysfunction in rats. Saudi Journal of Biological Sciences 19, 229-39. http://www.sciencedirect.com/science/article/pii/S1319562X1200006X

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Mustafa RA, Hamid AA, Mohamed S, Bakar FA Total Phenolic Compounds, Flavonoids, and Radical Scavenging Activity of 21 Selected Tropical Plants. Journal of Food Science 75, C28-C35. http://dx.doi.org/10.1111/j.1750-3841.2009.01401.x

Nithiyanantham S, Selvakumar S, Siddhuraju P Total phenolic content and antioxidant activity of two different solvent extracts from raw and processed legumes, Cicer arietinum L. and Pisum sativum L. Journal of Food Composition and Analysis 27, 52-60. http://www.sciencedirect.com/science/article/pii/S0889157512000749

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Grateful acknowledgment is made to the following: for plant names: Australian Plant Name Index, Australian National Herbarium http://www.anbg.gov.au/cpbr/databases/apni-search-full.html; ; The International Plant Names Index, Royal Botanic Gardens, Kew/Harvard University Herbaria/Australian National Herbarium http://www.ipni.org/index.html; Plants Database, United States Department of Agriculture, National Resources Conservation Service http://plants.usda.gov/;DJ Mabberley (1997) The Plant Book, Cambridge University Press (Second Edition); JH Wiersma and B Leon (1999) World Economic Plants, CRC Press; RJ Hnatiuk (1990) Census of Australian Vascular Plants, Australian Government Publishing Service; for information: Science Direct http://www.sciencedirect.com/; Wiley Online Library http://onlinelibrary.wiley.com/advanced/search; High Wire http://highwire.stanford.edu/cgi/search; Oxford Journals http://services.oxfordjournals.org/search.dtl; USDA National Agricultural Library http://agricola.nal.usda.gov/booleancube/booleancube_search_cit.html; for synonyms: The Plant List http://www.theplantlist.org/; for common names: http://en.wikipedia.org/wiki/Main_Page; etc.


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